IT1207990B - Attivita' analgesica, processo per derivati metil-piperazinici edla loro preparazione e composizioni terapeutiche che li contengono. - Google Patents

Attivita' analgesica, processo per derivati metil-piperazinici edla loro preparazione e composizioni terapeutiche che li contengono.

Info

Publication number
IT1207990B
IT1207990B IT8323720A IT2372083A IT1207990B IT 1207990 B IT1207990 B IT 1207990B IT 8323720 A IT8323720 A IT 8323720A IT 2372083 A IT2372083 A IT 2372083A IT 1207990 B IT1207990 B IT 1207990B
Authority
IT
Italy
Prior art keywords
methyl
contain
preparation
therapeutic compositions
analgesic activity
Prior art date
Application number
IT8323720A
Other languages
English (en)
Other versions
IT8323720A0 (it
Inventor
Diego Furlan
Original Assignee
Euroresearch Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euroresearch Srl filed Critical Euroresearch Srl
Priority to IT8323720A priority Critical patent/IT1207990B/it
Publication of IT8323720A0 publication Critical patent/IT8323720A0/it
Priority to EP84113225A priority patent/EP0142756A3/en
Priority to US06/667,714 priority patent/US4562191A/en
Priority to JP59239579A priority patent/JPS60116671A/ja
Priority to KR1019840007162A priority patent/KR850003725A/ko
Application granted granted Critical
Publication of IT1207990B publication Critical patent/IT1207990B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT8323720A 1983-11-15 1983-11-15 Attivita' analgesica, processo per derivati metil-piperazinici edla loro preparazione e composizioni terapeutiche che li contengono. IT1207990B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT8323720A IT1207990B (it) 1983-11-15 1983-11-15 Attivita' analgesica, processo per derivati metil-piperazinici edla loro preparazione e composizioni terapeutiche che li contengono.
EP84113225A EP0142756A3 (en) 1983-11-15 1984-11-02 Methyl-piperazino derivatives with analgesic activity, a process for their preparation, and therapeutic compounds which contain them
US06/667,714 US4562191A (en) 1983-11-15 1984-11-02 Methyl-piperazino derivatives with analgesic activity
JP59239579A JPS60116671A (ja) 1983-11-15 1984-11-15 鎮痛活性を伴うメチル‐ピペリジン誘導体、その製造方法およびそれ等を含む治療用組成物
KR1019840007162A KR850003725A (ko) 1983-11-15 1984-11-15 메틸-피페라진 유도체의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8323720A IT1207990B (it) 1983-11-15 1983-11-15 Attivita' analgesica, processo per derivati metil-piperazinici edla loro preparazione e composizioni terapeutiche che li contengono.

Publications (2)

Publication Number Publication Date
IT8323720A0 IT8323720A0 (it) 1983-11-15
IT1207990B true IT1207990B (it) 1989-06-01

Family

ID=11209419

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8323720A IT1207990B (it) 1983-11-15 1983-11-15 Attivita' analgesica, processo per derivati metil-piperazinici edla loro preparazione e composizioni terapeutiche che li contengono.

Country Status (5)

Country Link
US (1) US4562191A (it)
EP (1) EP0142756A3 (it)
JP (1) JPS60116671A (it)
KR (1) KR850003725A (it)
IT (1) IT1207990B (it)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2882271A (en) * 1959-04-14 Xcixcxh
US3318876A (en) * 1962-12-11 1967-05-09 Lepetit Spa Substituted piperazines and process for preparing same
FR1397193A (fr) * 1963-12-06 1965-04-30 Lepetit Spa Procédé de préparation de nouveaux dérivés de la pipérazine
FR7170M (it) * 1966-12-28 1969-08-11
JPS4986382A (it) * 1972-12-26 1974-08-19
JPS52286A (en) * 1975-05-27 1977-01-05 Kyorin Pharmaceut Co Ltd Method of preparing 1-(3-phenylpropyl)-4-acylpiperazine derivatives
SE411347B (sv) * 1975-05-27 1979-12-17 Kyorin Seiyaku Kk Forfarande for framstellning av 1-(3-fenylpropyl)-4-(beta-alkoxiakryloyl)-piperazinderivat
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique
US4368199A (en) * 1980-01-21 1983-01-11 Delalande S.A. Novel derivatives of 3,4,5-trimethoxy cinnamoyl piperazine, their salts, the process for preparing the same and their application in therapeutics
ATE10193T1 (de) * 1980-06-16 1984-11-15 Ab Ferrosan Diphenylbutyl-1-acylpiperazine.

Also Published As

Publication number Publication date
US4562191A (en) 1985-12-31
KR850003725A (ko) 1985-06-26
JPS60116671A (ja) 1985-06-24
EP0142756A3 (en) 1986-02-19
IT8323720A0 (it) 1983-11-15
EP0142756A2 (en) 1985-05-29

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