SE445173B - Oral, antihypertensiv komposition innehallande (d-3-merkapto-2-metylpropanoyl)-l-prolin och visst diuretikum - Google Patents

Oral, antihypertensiv komposition innehallande (d-3-merkapto-2-metylpropanoyl)-l-prolin och visst diuretikum

Info

Publication number
SE445173B
SE445173B SE7813277A SE7813277A SE445173B SE 445173 B SE445173 B SE 445173B SE 7813277 A SE7813277 A SE 7813277A SE 7813277 A SE7813277 A SE 7813277A SE 445173 B SE445173 B SE 445173B
Authority
SE
Sweden
Prior art keywords
proline
mercapto
methylpropanoyl
compound
diuretic
Prior art date
Application number
SE7813277A
Other languages
English (en)
Swedish (sv)
Other versions
SE7813277L (sv
Inventor
Z P Horovitz
B Rubin
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25343256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE445173(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of SE7813277L publication Critical patent/SE7813277L/xx
Publication of SE445173B publication Critical patent/SE445173B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE7813277A 1977-12-27 1978-12-22 Oral, antihypertensiv komposition innehallande (d-3-merkapto-2-metylpropanoyl)-l-prolin och visst diuretikum SE445173B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86442877A 1977-12-27 1977-12-27

Publications (2)

Publication Number Publication Date
SE7813277L SE7813277L (sv) 1979-06-28
SE445173B true SE445173B (sv) 1986-06-09

Family

ID=25343256

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7813277A SE445173B (sv) 1977-12-27 1978-12-22 Oral, antihypertensiv komposition innehallande (d-3-merkapto-2-metylpropanoyl)-l-prolin och visst diuretikum

Country Status (30)

Country Link
JP (1) JPS54110333A (nl)
AR (1) AR230378A1 (nl)
AU (1) AU526239B2 (nl)
BE (1) BE873092A (nl)
CA (1) CA1120400A (nl)
CH (1) CH642542A5 (nl)
DE (1) DE2854316C3 (nl)
DK (1) DK578778A (nl)
EG (1) EG14178A (nl)
FI (1) FI783991A (nl)
FR (1) FR2413089A1 (nl)
GB (1) GB2010675B (nl)
GR (1) GR72951B (nl)
HK (1) HK45483A (nl)
HU (1) HU178747B (nl)
IE (1) IE48306B1 (nl)
IL (1) IL56281A (nl)
IT (1) IT1202811B (nl)
KE (1) KE3235A (nl)
LU (1) LU80709A1 (nl)
MY (2) MY8300240A (nl)
NL (2) NL192870C (nl)
NO (1) NO784357L (nl)
NZ (1) NZ189159A (nl)
PH (1) PH22111A (nl)
PL (1) PL212188A1 (nl)
PT (1) PT68983A (nl)
SE (1) SE445173B (nl)
SG (1) SG41482G (nl)
ZA (1) ZA786948B (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829950B2 (ja) * 1978-10-05 1983-06-25 ウェルファイド株式会社 環状イミノカルボン酸誘導体およびその塩類
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4482725A (en) * 1980-04-03 1984-11-13 E. R. Squibb & Sons, Inc. S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4532342A (en) * 1981-02-20 1985-07-30 Warner-Lambert Company N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4552889A (en) * 1983-06-09 1985-11-12 Eli Lilly And Company 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
DE3532036A1 (de) * 1985-09-09 1987-03-26 Hoechst Ag Pharmazeutische zubereitung zur behandlung des bluthochdrucks
DK9200258U4 (da) * 1992-03-11 1993-07-23 Merck & Co Inc Farmaceutisk præparat indeholdende enalapril til brug mod hypertension
WO1996024358A1 (en) * 1995-02-10 1996-08-15 G.D. Searle & Co. Use of low dose amount of spironolactone for treatment of cardiovascular disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
AU526239B2 (en) 1982-12-23
NL192870C (nl) 1998-04-02
DE2854316A1 (de) 1979-07-05
IT1202811B (it) 1989-02-09
IL56281A (en) 1983-05-15
IT7831266A0 (it) 1978-12-22
MY102991A (en) 1993-03-31
NL7812164A (nl) 1979-06-29
GR72951B (nl) 1984-01-17
HK45483A (en) 1983-10-28
BE873092A (fr) 1979-06-27
FR2413089B1 (nl) 1980-12-26
SG41482G (en) 1985-01-11
SE7813277L (sv) 1979-06-28
MY8300240A (en) 1983-12-31
AR230378A1 (es) 1984-04-30
JPS647045B2 (nl) 1989-02-07
NL980017I1 (nl) 1998-07-01
DE2854316C2 (nl) 1989-08-10
PH22111A (en) 1988-06-01
CH642542A5 (de) 1984-04-30
GB2010675A (en) 1979-07-04
LU80709A1 (de) 1979-04-13
IL56281A0 (en) 1979-03-12
CA1120400A (en) 1982-03-23
ZA786948B (en) 1980-04-30
IE48306B1 (en) 1984-12-12
NO784357L (no) 1979-06-28
IE782413L (en) 1979-06-27
DK578778A (da) 1979-06-28
NZ189159A (en) 1984-12-14
DE2854316C3 (de) 1994-12-22
FR2413089A1 (fr) 1979-07-27
FI783991A (fi) 1979-06-28
AU4204178A (en) 1979-07-05
JPS54110333A (en) 1979-08-29
PL212188A1 (nl) 1980-02-11
KE3235A (en) 1982-11-05
HU178747B (en) 1982-06-28
GB2010675B (en) 1982-06-16
NL192870B (nl) 1997-12-01
PT68983A (en) 1979-01-01
EG14178A (en) 1984-06-30

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