IE782413L - Anti-hypertensive composition - Google Patents

Anti-hypertensive composition

Info

Publication number
IE782413L
IE782413L IE782413A IE241378A IE782413L IE 782413 L IE782413 L IE 782413L IE 782413 A IE782413 A IE 782413A IE 241378 A IE241378 A IE 241378A IE 782413 L IE782413 L IE 782413L
Authority
IE
Ireland
Prior art keywords
alkyl
phenyl
compound
hypertensive composition
hypertensive
Prior art date
Application number
IE782413A
Other versions
IE48306B1 (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25343256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE782413(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IE782413L publication Critical patent/IE782413L/en
Publication of IE48306B1 publication Critical patent/IE48306B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method for reducing blood pressure comprises administering a combination of a diuretic compound (specified) and a compound having the general formula <IMAGE> R = OH1 alkoxy or NH2 R1 & R4 = H1 alkyl or phenyl alkyl R2 = H or R5CO R3 = H1 OH or alkyl R5 = alkyl, phenyl, or phenyl alkyl n = 0 - 2.a [GB2010675A]
IE2413/78A 1977-12-27 1978-12-06 Medicaments for treating hypertension IE48306B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86442877A 1977-12-27 1977-12-27

Publications (2)

Publication Number Publication Date
IE782413L true IE782413L (en) 1979-06-27
IE48306B1 IE48306B1 (en) 1984-12-12

Family

ID=25343256

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2413/78A IE48306B1 (en) 1977-12-27 1978-12-06 Medicaments for treating hypertension

Country Status (30)

Country Link
JP (1) JPS54110333A (en)
AR (1) AR230378A1 (en)
AU (1) AU526239B2 (en)
BE (1) BE873092A (en)
CA (1) CA1120400A (en)
CH (1) CH642542A5 (en)
DE (1) DE2854316C3 (en)
DK (1) DK578778A (en)
EG (1) EG14178A (en)
FI (1) FI783991A (en)
FR (1) FR2413089A1 (en)
GB (1) GB2010675B (en)
GR (1) GR72951B (en)
HK (1) HK45483A (en)
HU (1) HU178747B (en)
IE (1) IE48306B1 (en)
IL (1) IL56281A (en)
IT (1) IT1202811B (en)
KE (1) KE3235A (en)
LU (1) LU80709A1 (en)
MY (2) MY8300240A (en)
NL (2) NL192870C (en)
NO (1) NO784357L (en)
NZ (1) NZ189159A (en)
PH (1) PH22111A (en)
PL (1) PL212188A1 (en)
PT (1) PT68983A (en)
SE (1) SE445173B (en)
SG (1) SG41482G (en)
ZA (1) ZA786948B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5829950B2 (en) * 1978-10-05 1983-06-25 ウェルファイド株式会社 Cyclic iminocarboxylic acid derivatives and their salts
US4350704A (en) 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4482725A (en) * 1980-04-03 1984-11-13 E. R. Squibb & Sons, Inc. S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4532342A (en) * 1981-02-20 1985-07-30 Warner-Lambert Company N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4552889A (en) * 1983-06-09 1985-11-12 Eli Lilly And Company 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
DE3532036A1 (en) * 1985-09-09 1987-03-26 Hoechst Ag PHARMACEUTICAL PREPARATION FOR TREATING HIGH PRESSURE
DK9200258U4 (en) * 1992-03-11 1993-07-23 Merck & Co Inc Pharmaceutical preparation containing enalapril for use in hypertension
WO1996024358A1 (en) * 1995-02-10 1996-08-15 G.D. Searle & Co. Use of low dose amount of spironolactone for treatment of cardiovascular disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
GR72951B (en) 1984-01-17
FR2413089B1 (en) 1980-12-26
AU4204178A (en) 1979-07-05
HK45483A (en) 1983-10-28
PL212188A1 (en) 1980-02-11
IL56281A0 (en) 1979-03-12
AU526239B2 (en) 1982-12-23
KE3235A (en) 1982-11-05
LU80709A1 (en) 1979-04-13
MY102991A (en) 1993-03-31
FI783991A (en) 1979-06-28
DE2854316C3 (en) 1994-12-22
IE48306B1 (en) 1984-12-12
CA1120400A (en) 1982-03-23
NL980017I1 (en) 1998-07-01
JPS54110333A (en) 1979-08-29
JPS647045B2 (en) 1989-02-07
DE2854316A1 (en) 1979-07-05
CH642542A5 (en) 1984-04-30
NO784357L (en) 1979-06-28
NL192870C (en) 1998-04-02
GB2010675B (en) 1982-06-16
NZ189159A (en) 1984-12-14
FR2413089A1 (en) 1979-07-27
PT68983A (en) 1979-01-01
NL7812164A (en) 1979-06-29
SE7813277L (en) 1979-06-28
ZA786948B (en) 1980-04-30
IT7831266A0 (en) 1978-12-22
PH22111A (en) 1988-06-01
DE2854316C2 (en) 1989-08-10
HU178747B (en) 1982-06-28
GB2010675A (en) 1979-07-04
MY8300240A (en) 1983-12-31
IL56281A (en) 1983-05-15
SG41482G (en) 1985-01-11
DK578778A (en) 1979-06-28
AR230378A1 (en) 1984-04-30
SE445173B (en) 1986-06-09
BE873092A (en) 1979-06-27
NL192870B (en) 1997-12-01
EG14178A (en) 1984-06-30
IT1202811B (en) 1989-02-09

Similar Documents

Publication Publication Date Title
IE832818L (en) Phenethylamine derivatives
ES8706664A1 (en) Carbostyril compounds, compositions containing same and processes for preparing same.
IE780515L (en) Morphine derivatives
IE782413L (en) Anti-hypertensive composition
CA2149872A1 (en) Diabetes prevention and treatment
IE780145L (en) Meta-sulphonamido-benzamides
AU560607B2 (en) Pyridazinones their preparation and use and medicaments containing pyridazinones
IE800449L (en) Pyrazoline derivatives.
AU3421589A (en) Carbamoyl-2-pyrrolidinone compounds
IE832110L (en) 1-arylcyclobutylmethylamine compounds
AU5057193A (en) The preparation of 7-acyl-3-(substituted carbamoyloxy)cephem compounds
IE780514L (en) Morphine derivatives
JPS6470412A (en) Medicinal composition
IE44830L (en) Benzodiazepine derivatives.
IE791930L (en) Cyclohexadienes.
MY130190A (en) Method for the preparation of 4-halo-2&#39;- nitrobutyrophenone compounds
JPS5424882A (en) Novel heterocyclic compounds and their preparation
IE45096L (en) Thiadiazole derivatives
EP0072508A3 (en) Pyrazolone derivatives, their preparation and use as coupling components
AU1287892A (en) Method of inhibiting the progressive development of diabetes mellitus
JPS53127466A (en) Thiocarbamate type heterocyclic compounds and its preparation
AU579416B2 (en) 3-Amino-2,3-dihydro-1-benzoxepine-compounds and methods for their preparation and pharmaceutical preparations containing these compounds
JPS523081A (en) Preparation of sulfonylpyridazionones
JPS52102247A (en) Novel phenylalanine derivatives
AU564739B2 (en) Acridanone derivatives