SE442201B - 2-/3-/4-(3-kloro-4-fluoro-fenyl-1-piperazinyl/arpayl/-1,2,4-triazolo/4,3-a/pyridin-3(2h)-on, forfarande for framstellning derav och komposition derav - Google Patents

2-/3-/4-(3-kloro-4-fluoro-fenyl-1-piperazinyl/arpayl/-1,2,4-triazolo/4,3-a/pyridin-3(2h)-on, forfarande for framstellning derav och komposition derav

Info

Publication number
SE442201B
SE442201B SE8102093A SE8102093A SE442201B SE 442201 B SE442201 B SE 442201B SE 8102093 A SE8102093 A SE 8102093A SE 8102093 A SE8102093 A SE 8102093A SE 442201 B SE442201 B SE 442201B
Authority
SE
Sweden
Prior art keywords
chloro
triazolo
pharmaceutically acceptable
piperazinyl
pyridin
Prior art date
Application number
SE8102093A
Other languages
English (en)
Swedish (sv)
Other versions
SE8102093L (sv
Inventor
B Silvestrini
L Baiocchi
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of SE8102093L publication Critical patent/SE8102093L/xx
Publication of SE442201B publication Critical patent/SE442201B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE8102093A 1980-04-09 1981-04-01 2-/3-/4-(3-kloro-4-fluoro-fenyl-1-piperazinyl/arpayl/-1,2,4-triazolo/4,3-a/pyridin-3(2h)-on, forfarande for framstellning derav och komposition derav SE442201B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21246/80A IT1147349B (it) 1980-04-09 1980-04-09 2-parentesi quadra aperta 3-parentesi quadra aperta 4-(3-cloro-4-fluorofenil)-1-piperfrazinil parentesi quadra propil parentesi quadra chiusa-1,2,4-triazolo parentesi quadra aperta 4,3 parentesi quadra chiusa piridin-3(2h)-one

Publications (2)

Publication Number Publication Date
SE8102093L SE8102093L (sv) 1981-10-10
SE442201B true SE442201B (sv) 1985-12-09

Family

ID=11178966

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8102093A SE442201B (sv) 1980-04-09 1981-04-01 2-/3-/4-(3-kloro-4-fluoro-fenyl-1-piperazinyl/arpayl/-1,2,4-triazolo/4,3-a/pyridin-3(2h)-on, forfarande for framstellning derav och komposition derav

Country Status (21)

Country Link
US (1) US4402956A (fi)
JP (1) JPS56158784A (fi)
KR (1) KR840002292B1 (fi)
AR (1) AR225076A1 (fi)
AT (1) AT377262B (fi)
AU (1) AU529605B2 (fi)
BE (1) BE887547A (fi)
CA (1) CA1176253A (fi)
CH (1) CH652397A5 (fi)
DE (1) DE3112984A1 (fi)
ES (1) ES8202817A1 (fi)
FI (1) FI69306C (fi)
FR (1) FR2480285A1 (fi)
GB (1) GB2073747B (fi)
GR (1) GR73620B (fi)
IL (1) IL62101A (fi)
IT (1) IT1147349B (fi)
NL (1) NL8100998A (fi)
PT (1) PT72813B (fi)
SE (1) SE442201B (fi)
YU (1) YU83181A (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952502A (en) * 1996-11-12 1999-09-14 Sepracor Inc. 2R,4S,R, S- and 2S,4R,R,S-hydroxyitraconazole
CN1102592C (zh) 1996-11-12 2003-03-05 塞普拉科公司 2r,4s,s,s－和2s,4r,s,s－羟基伊曲康唑
US6147077A (en) * 1999-04-29 2000-11-14 Sepracor Inc. 2R,4S-hydroxyitraconazole isomers
US8686158B2 (en) * 2008-06-05 2014-04-01 President And Fellows Of Harvard College High-valent palladium fluoride complexes and uses thereof
KR20110095898A (ko) 2008-11-20 2011-08-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 유기 화합물의 플루오르화
EP2385944A4 (en) * 2009-01-09 2013-06-19 Harvard College FLUORINATED COMPOUNDS AND METHODS OF USE
US9150516B2 (en) 2011-04-12 2015-10-06 President And Fellows Of Harvard College Fluorination of organic compounds
WO2014052622A1 (en) 2012-09-26 2014-04-03 President And Fellows Of Harvard College Nickel fluorinating complexes and uses thereof
WO2015058047A2 (en) 2013-10-18 2015-04-23 President And Fellows Of Harvard College Fluorination of organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
FR8135M (fi) * 1968-12-31 1970-08-10
US4267179A (en) * 1978-06-23 1981-05-12 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
UST100505I4 (en) 1980-03-17 1981-04-07 Triazolo[4,3-a]pyridin-3(2H)-ones

Also Published As

Publication number Publication date
GB2073747A (en) 1981-10-21
ES501188A0 (es) 1982-02-01
BE887547A (fr) 1981-06-15
PT72813A (en) 1981-05-01
YU83181A (en) 1983-12-31
IT8021246A0 (it) 1980-04-09
KR840002292B1 (ko) 1984-12-15
PT72813B (en) 1982-04-02
NL8100998A (nl) 1981-11-02
FI811000L (fi) 1981-10-10
FR2480285A1 (fr) 1981-10-16
SE8102093L (sv) 1981-10-10
ATA165081A (de) 1984-07-15
AR225076A1 (es) 1982-02-15
GR73620B (fi) 1984-03-26
FR2480285B1 (fi) 1984-02-24
JPS56158784A (en) 1981-12-07
AT377262B (de) 1985-02-25
IL62101A0 (en) 1981-03-31
CH652397A5 (it) 1985-11-15
AU6904381A (en) 1981-10-15
AU529605B2 (en) 1983-06-16
KR830005218A (ko) 1983-08-03
FI69306B (fi) 1985-09-30
IL62101A (en) 1984-01-31
ES8202817A1 (es) 1982-02-01
IT1147349B (it) 1986-11-19
DE3112984A1 (de) 1981-12-24
CA1176253A (en) 1984-10-16
GB2073747B (en) 1983-09-07
FI69306C (fi) 1986-01-10
US4402956A (en) 1983-09-06

Similar Documents

Publication Publication Date Title
US10004701B2 (en) Methods and compositions for treating infection
JP6772272B2 (ja) シクロヘキサン誘導体、又はその立体異性体、又はその塩及びその調製と応用
MX2010012186A (es) Antagonistas del receptor nmda para el tratamiento de transtornos neuropsiquitricos.
AU2008252620B2 (en) (thio) -carbamoyl-cyclohexane derivatives and method for treating schizophrenia
ES2929140T3 (es) Imidazoles sustituidos con fenilo y piridinilo como moduladores de RORgammat
US20120046246A1 (en) Methods for treating osteoclast-related disease, compounds and compositions thereof
FR2513250A1 (fr) Nouvelles cyclobutene-3,4-diones substituees
JP2017538676A (ja) ミトコンドリア透過性遷移孔（ｍｔＰＴＰ）の小分子阻害剤
AU2006301708A1 (en) Glycyrrhetinic acid-30-amide derivatives and the uses thereof
CA3166938A1 (en) Methods of treating erythropoietic protoporphyria, x-linked protoporphyria, or congenital erythropoietic porphyria with glycine transport inhibitors
JP2016185947A (ja) ＩＲＥ−１αインヒビター
SE442201B (sv) 2-/3-/4-(3-kloro-4-fluoro-fenyl-1-piperazinyl/arpayl/-1,2,4-triazolo/4,3-a/pyridin-3(2h)-on, forfarande for framstellning derav och komposition derav
CN113924094A (zh) 酯取代的离子通道阻滞剂及其使用方法
KR100570374B1 (ko) 5-ｈｔ3 및 신경세포의 니코틴작용성 수용체 길항물질로서의 1-아미노-알킬시클로헥산 화합물을 이용한 치료방법 및 이 화합물을 함유하는 약학적 조성물
JP2021512138A (ja) ２−（αヒドロキシペンチル）安息香酸の有機アミンエステル誘導体薬物
KR101455484B1 (ko) 항말라리아제로서 피페라진
WO2013070107A1 (ru) ПРОИЗВОДНЫЕ 5Н-ДИБЕНЗО[b,е] [1,4]ДИАЗЕПИНA И ИХ ПРИМЕНЕНИЕ
CN102603553B (zh) 具有协同抗真菌作用的化合物及其在药学中的用途
TW200306189A (en) Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists
US9932302B1 (en) N-phenyl and N-benzyl enaminones and methods for using same
CN104744451A (zh) 一种1-(3-氨基丙基)取代环状胺类化合物、其制备方法、药物组合物及用途
US20100173903A1 (en) Bicyclic amide derivatives for the treatmet of respiratory disorders
CN116410160B (zh) 一种牛蒡子苷元衍生物及其制备方法与应用
RU2008149076A (ru) Действующее вещество для лечения алкогольной зависимости, фармацевтическая композиция, лекарственное средство, способ получения фармацевтической композиции и лекарственного средства и способ лечения
CA3213395A1 (en) Compositions and methods for treating polycythemia

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8102093-5

Effective date: 19880822

Format of ref document f/p: F