SE435057B - 2-(2-((4-metoxibensoyl)amino)fenyl) etyl-1-(legre alkyl eller bensyl) piperidiniumhalider och forfarande for framstellning av dessa - Google Patents
2-(2-((4-metoxibensoyl)amino)fenyl) etyl-1-(legre alkyl eller bensyl) piperidiniumhalider och forfarande for framstellning av dessaInfo
- Publication number
- SE435057B SE435057B SE8205535A SE8205535A SE435057B SE 435057 B SE435057 B SE 435057B SE 8205535 A SE8205535 A SE 8205535A SE 8205535 A SE8205535 A SE 8205535A SE 435057 B SE435057 B SE 435057B
- Authority
- SE
- Sweden
- Prior art keywords
- phenyl
- ethyl
- amino
- compound
- methoxybenzoyl
- Prior art date
Links
- -1 AMINO Chemical class 0.000 title claims description 5
- 238000000034 method Methods 0.000 title claims description 5
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical class [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 title 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims description 11
- 150000004820 halides Chemical group 0.000 claims description 6
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 5
- PJWPNDMDCLXCOM-UHFFFAOYSA-N encainide Chemical compound C1=CC(OC)=CC=C1C(=O)NC1=CC=CC=C1CCC1N(C)CCCC1 PJWPNDMDCLXCOM-UHFFFAOYSA-N 0.000 claims description 5
- 229960001142 encainide Drugs 0.000 claims description 5
- 239000003416 antiarrhythmic agent Substances 0.000 claims description 4
- 229910052794 bromium Inorganic materials 0.000 claims description 4
- 238000010992 reflux Methods 0.000 claims description 4
- 231100000419 toxicity Toxicity 0.000 claims description 4
- 230000001988 toxicity Effects 0.000 claims description 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 3
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 3
- 229910052801 chlorine Inorganic materials 0.000 claims description 3
- 239000000460 chlorine Substances 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 238000004458 analytical method Methods 0.000 claims description 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims description 2
- 229910052740 iodine Inorganic materials 0.000 claims description 2
- 239000003960 organic solvent Substances 0.000 claims description 2
- XICNVRJHHCHOGI-UHFFFAOYSA-N n-[2-[2-(1-benzyl-1-methylpiperidin-1-ium-2-yl)ethyl]phenyl]-4-methoxybenzamide;bromide;hydrate Chemical compound O.[Br-].C1=CC(OC)=CC=C1C(=O)NC1=CC=CC=C1CCC1[N+](CC=2C=CC=CC=2)(C)CCCC1 XICNVRJHHCHOGI-UHFFFAOYSA-N 0.000 claims 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- AGEZXYOZHKGVCM-UHFFFAOYSA-N benzyl bromide Chemical compound BrCC1=CC=CC=C1 AGEZXYOZHKGVCM-UHFFFAOYSA-N 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 239000012467 final product Substances 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- VOGFBLDDNZRUDZ-UHFFFAOYSA-N n-[2-[2-(1,1-dimethylpiperidin-1-ium-2-yl)ethyl]phenyl]-4-methoxybenzamide;iodide Chemical compound [I-].C1=CC(OC)=CC=C1C(=O)NC1=CC=CC=C1CCC1[N+](C)(C)CCCC1 VOGFBLDDNZRUDZ-UHFFFAOYSA-N 0.000 claims 1
- PARNNBHKHKKNQF-UHFFFAOYSA-N n-[2-[2-(1-benzyl-1-methylpiperidin-1-ium-2-yl)ethyl]phenyl]-4-methoxybenzamide;bromide Chemical compound [Br-].C1=CC(OC)=CC=C1C(=O)NC1=CC=CC=C1CCC1[N+](CC=2C=CC=CC=2)(C)CCCC1 PARNNBHKHKKNQF-UHFFFAOYSA-N 0.000 claims 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 15
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 6
- 241000699670 Mus sp. Species 0.000 description 5
- 238000005481 NMR spectroscopy Methods 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 206010003119 arrhythmia Diseases 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 description 2
- LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 description 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 208000012902 Nervous system disease Diseases 0.000 description 1
- 208000025966 Neurological disease Diseases 0.000 description 1
- 241000906446 Theraps Species 0.000 description 1
- 206010047281 Ventricular arrhythmia Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003288 anthiarrhythmic effect Effects 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 description 1
- 231100001231 less toxic Toxicity 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 229960001404 quinidine Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000012265 solid product Substances 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/229,244 US4321386A (en) | 1981-01-28 | 1981-01-28 | Quaternary piperidinium halides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8205535D0 SE8205535D0 (sv) | 1982-09-28 |
| SE8205535L SE8205535L (sv) | 1982-09-28 |
| SE435057B true SE435057B (sv) | 1984-09-03 |
Family
ID=22860396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8205535A SE435057B (sv) | 1981-01-28 | 1982-09-28 | 2-(2-((4-metoxibensoyl)amino)fenyl) etyl-1-(legre alkyl eller bensyl) piperidiniumhalider och forfarande for framstellning av dessa |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4321386A (da) |
| JP (1) | JPH0348904B2 (da) |
| AR (1) | AR230266A1 (da) |
| AT (1) | AT378183B (da) |
| AU (1) | AU551523B2 (da) |
| BE (1) | BE891938A (da) |
| CA (1) | CA1184917A (da) |
| CH (1) | CH651021A5 (da) |
| DE (1) | DE3223499T1 (da) |
| DK (1) | DK156649C (da) |
| FI (1) | FI65239C (da) |
| GB (1) | GB2100736B (da) |
| GR (1) | GR74720B (da) |
| IE (1) | IE52420B1 (da) |
| IT (1) | IT1147809B (da) |
| NL (1) | NL8220049A (da) |
| SE (1) | SE435057B (da) |
| WO (1) | WO1982002551A1 (da) |
| YU (1) | YU43063B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG176772A1 (en) * | 2009-04-09 | 2012-01-30 | Cognition Therapeutics Inc | Inhibitors of cognitive decline |
| ES2547730T3 (es) | 2009-07-31 | 2015-10-08 | Cognition Therapeutics, Inc. | Inhibidores del deterioro cognitivo |
| AU2012212219B2 (en) | 2011-02-02 | 2017-03-23 | Cognition Therapeutics, Inc. | Isolated compounds from turmeric oil and methods of use |
| AU2015210852B2 (en) | 2014-01-31 | 2019-01-24 | Cognition Therapeutics, Inc. | Isoindoline compositions and methods for treating neurodegenerative disease |
| CA3061787A1 (en) | 2017-05-15 | 2018-11-22 | Cognition Therapeutics, Inc. | Compositions for treating neurodegenerative diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3037910A (en) * | 1958-04-18 | 1962-06-05 | Burroughs Wellcome Co | Process for treatment of hypertension |
| US3931195A (en) * | 1971-03-03 | 1976-01-06 | Mead Johnson & Company | Substituted piperidines |
| US3917679A (en) * | 1974-04-12 | 1975-11-04 | Lilly Co Eli | Quaternary ammonium salts of N-dialkylaminoalkyl-N-(2-indanyl)anilines |
-
1981
- 1981-01-28 US US06/229,244 patent/US4321386A/en not_active Expired - Lifetime
-
1982
- 1982-01-27 GB GB08220076A patent/GB2100736B/en not_active Expired
- 1982-01-27 WO PCT/US1982/000108 patent/WO1982002551A1/en active IP Right Grant
- 1982-01-27 CH CH5828/82A patent/CH651021A5/de not_active IP Right Cessation
- 1982-01-27 AU AU81485/82A patent/AU551523B2/en not_active Ceased
- 1982-01-27 AT AT0900782A patent/AT378183B/de active
- 1982-01-27 JP JP57500784A patent/JPH0348904B2/ja not_active Expired - Lifetime
- 1982-01-27 DE DE823223499T patent/DE3223499T1/de active Granted
- 1982-01-28 CA CA000395068A patent/CA1184917A/en not_active Expired
- 1982-01-28 YU YU197/82A patent/YU43063B/xx unknown
- 1982-01-28 IT IT47667/82A patent/IT1147809B/it active
- 1982-01-28 NL NL8220049A patent/NL8220049A/nl unknown
- 1982-01-28 GR GR67146A patent/GR74720B/el unknown
- 1982-01-28 IE IE191/82A patent/IE52420B1/en unknown
- 1982-01-28 AR AR288281A patent/AR230266A1/es active
- 1982-01-28 BE BE0/207171A patent/BE891938A/fr not_active IP Right Cessation
- 1982-07-08 FI FI822443A patent/FI65239C/fi not_active IP Right Cessation
- 1982-09-27 DK DK429382A patent/DK156649C/da not_active IP Right Cessation
- 1982-09-28 SE SE8205535A patent/SE435057B/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IT1147809B (it) | 1986-11-26 |
| AU8148582A (en) | 1982-08-16 |
| DK156649B (da) | 1989-09-18 |
| DK429382A (da) | 1982-09-27 |
| IE52420B1 (en) | 1987-10-28 |
| IE820191L (en) | 1982-07-28 |
| SE8205535D0 (sv) | 1982-09-28 |
| DE3223499C2 (da) | 1989-11-23 |
| ATA900782A (de) | 1984-11-15 |
| FI822443L (fi) | 1982-07-08 |
| CA1184917A (en) | 1985-04-02 |
| CH651021A5 (de) | 1985-08-30 |
| BE891938A (fr) | 1982-07-28 |
| GB2100736A (en) | 1983-01-06 |
| YU43063B (en) | 1989-02-28 |
| FI65239B (fi) | 1983-12-30 |
| AR230266A1 (es) | 1984-03-01 |
| SE8205535L (sv) | 1982-09-28 |
| WO1982002551A1 (en) | 1982-08-05 |
| US4321386A (en) | 1982-03-23 |
| YU19782A (en) | 1985-04-30 |
| DE3223499T1 (de) | 1983-01-13 |
| DK156649C (da) | 1990-02-05 |
| IT8247667A0 (it) | 1982-01-28 |
| FI65239C (fi) | 1984-04-10 |
| GB2100736B (en) | 1985-01-30 |
| NL8220049A (nl) | 1982-11-01 |
| AT378183B (de) | 1985-06-25 |
| JPH0348904B2 (da) | 1991-07-25 |
| AU551523B2 (en) | 1986-05-01 |
| JPS57502216A (da) | 1982-12-16 |
| FI822443A0 (fi) | 1982-07-08 |
| GR74720B (da) | 1984-07-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2558600C (en) | A substituted-trialkyl amine compound with anti-viral activity based on antagonism against a chemokine receptor cxcr4 | |
| US5110933A (en) | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | |
| US8536183B2 (en) | 3-pyridylcarbonyl-piperazinylsulfonyl derivatives | |
| US3396224A (en) | Controlling phytopathogenic fungi on plants with 3-pyridyl methane derivatives | |
| Thomas et al. | Synthesis of acylguanidine analogs: inhibitors of ADP-induced platelet aggregation | |
| SE435057B (sv) | 2-(2-((4-metoxibensoyl)amino)fenyl) etyl-1-(legre alkyl eller bensyl) piperidiniumhalider och forfarande for framstellning av dessa | |
| Burke Jr et al. | Resolution, absolute configuration, and antiarrhythmic properties of the enantiomers of disopyramide, 4-(diisopropylamino)-2-(2-pyridyl)-2-phenylbutyramide | |
| Leeson et al. | Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel | |
| Hodgkinson et al. | Formation of complexes between aza derivatives of crown ethers and primary alkylammonium salts. Part 4. Diaza-18-crown-6 derivatives | |
| DE69020868T2 (de) | Heterozyklische Verbindungen. | |
| DK166776B1 (da) | 2,2,5,5-tetramethyl(pyrrolin eller pyrrolidin)-3-yl-carbonylaminoderivater, fremgangsmaade til deres fremstilling og farmaceutiske praeparater indeholdende dem | |
| US2746966A (en) | Esters of bis-(nu-substituted-3-hydroxypiperidinium) alkanes | |
| PT92324A (pt) | Processo para a preparacao de oxadiaminobutanos substituidos | |
| US2914533A (en) | Tertiary-aminoalkyl n-(pyridyl)carbamates and their preparation | |
| JPS6069089A (ja) | ジヒドロピリジン−５−ホスホネ−ト誘導体およびその製造法 | |
| Lampe et al. | Cardiotonic agents. 6. Histamine analogs as potential cardiovascular selective H2 agonists | |
| US3071613A (en) | N-(2, 2-dialkoxyethyl)-(halogenated-phenyl) alkylamines | |
| US2746967A (en) | Derivatives of bis-(nu-substituted-3-hydroxypiperidinium) alkanes | |
| US2553994A (en) | Pyridine therapeutic compounds | |
| US3117127A (en) | 3-and 4-acetamidopiperidinium halides | |
| Yoneyama et al. | Herbicidal activity of N-(2, 3-epoxypropyl) benzenesulfonamide derivatives | |
| FR2521137A1 (fr) | Halogenures de piperidinium quaternaire | |
| Kametani et al. | Synthesis of heterocyclic compounds. CCLXXXXV. Syntheses of benzomorphan and related compounds. II. The debenzylation of quaternary ammonium salts with thiophenol | |
| SE435058B (sv) | 4-metoxi-n-(2-(2-(1-metyl-2-piperidinyl)-etyl) fenyl) bensamid-n-oxid och forfarande for framstellning av denna | |
| JPS6016414B2 (ja) | エナミン類およびその製造方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 8205535-1 Effective date: 19930810 Format of ref document f/p: F |