SE422057B - Forfarande for framstellning av vissa omega-substituerade omega-nor-13,14-dehydro-prostaglandiner - Google Patents

Forfarande for framstellning av vissa omega-substituerade omega-nor-13,14-dehydro-prostaglandiner

Info

Publication number
SE422057B
SE422057B SE7509764A SE7509764A SE422057B SE 422057 B SE422057 B SE 422057B SE 7509764 A SE7509764 A SE 7509764A SE 7509764 A SE7509764 A SE 7509764A SE 422057 B SE422057 B SE 422057B
Authority
SE
Sweden
Prior art keywords
omega
prostaglandines
dehydro
procedure
substituted
Prior art date
Application number
SE7509764A
Other languages
English (en)
Swedish (sv)
Other versions
SE7509764L (sv
Inventor
C Gandolfi
R Pellegata
R Ceserani
M M Usardi
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of SE7509764L publication Critical patent/SE7509764L/xx
Publication of SE422057B publication Critical patent/SE422057B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018—Esters of cycloaliphatic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/564—Three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
SE7509764A 1974-09-25 1975-09-03 Forfarande for framstellning av vissa omega-substituerade omega-nor-13,14-dehydro-prostaglandiner SE422057B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT27654/74A IT1053781B (it) 1974-09-25 1974-09-25 Omega nor cicloalcil 13.14 deidro prostaglandine

Publications (2)

Publication Number Publication Date
SE7509764L SE7509764L (sv) 1976-03-26
SE422057B true SE422057B (sv) 1982-02-15

Family

ID=11222055

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7509764A SE422057B (sv) 1974-09-25 1975-09-03 Forfarande for framstellning av vissa omega-substituerade omega-nor-13,14-dehydro-prostaglandiner

Country Status (24)

Country Link
US (2) US4035415A (OSRAM)
JP (2) JPS5839156B2 (OSRAM)
AT (1) AT351184B (OSRAM)
BE (1) BE832983A (OSRAM)
CA (1) CA1083569A (OSRAM)
CH (1) CH617186A5 (OSRAM)
CS (1) CS191276B2 (OSRAM)
CY (1) CY954A (OSRAM)
DE (1) DE2539116C2 (OSRAM)
DK (1) DK155316C (OSRAM)
FI (1) FI63932C (OSRAM)
FR (2) FR2285866A1 (OSRAM)
GB (1) GB1483880A (OSRAM)
HK (1) HK42478A (OSRAM)
HU (1) HU174287B (OSRAM)
IL (1) IL48043A (OSRAM)
IT (1) IT1053781B (OSRAM)
KE (1) KE2851A (OSRAM)
MY (1) MY7800321A (OSRAM)
NL (1) NL187354C (OSRAM)
NO (1) NO146357C (OSRAM)
SE (1) SE422057B (OSRAM)
SU (1) SU652889A3 (OSRAM)
ZA (1) ZA755420B (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU501803B2 (en) * 1975-03-21 1979-06-28 Farmitalia Carlo Erba S.P.A. Fluoro-prostaglandins
DE2655004C3 (de) * 1976-12-02 1980-06-19 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von bicyclischen Laktonen
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
CH656877A5 (de) * 1981-11-27 1986-07-31 Erba Farmitalia Optisch aktive oder racemische prostaglandinderivate.
EP1348437A3 (en) * 1988-09-06 2003-11-19 Pharmacia Aktiebolag Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
DE4024347A1 (de) * 1990-07-27 1992-01-30 Schering Ag Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
US5741810A (en) * 1996-02-29 1998-04-21 Allergan Cyclopentane heptan(ene)oic acid, 2- heteroarylalkenyl derivatives as therapeutic agents
CZ305221B6 (cs) * 2013-12-10 2015-06-17 Univerzita Pardubice Způsob přípravy (3aR,4S,5R,6aS)-4-[(3S)-5-cyklohexyl-3-hydroxypent-1-yn-1-yl]-5-(ethoxymethoxy)-hexahydro-2H-cyklopenta[b]furan-2-onu

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843713A (en) * 1972-04-05 1974-10-22 Ciba Geigy Corp 16-lower alkoxy lower alkyl,-16-20 w-pentano,pge
GB1425961A (en) * 1972-04-13 1976-02-25 Erba Carlo Spa Prostanoic acid derivatives
US3876690A (en) * 1973-05-11 1975-04-08 American Cyanamid Co 1-alkoxy-9-keto-prostenoic acid derivatives
US3884909A (en) * 1973-09-24 1975-05-20 Standard Brands Inc Gelatinizable crosslinked cationic starch and method for its manufacture
HU176654B (en) * 1974-09-06 1981-04-28 Erba Farmitalia Process for producing pgf beta-prostaglandines
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner

Also Published As

Publication number Publication date
NL187354C (nl) 1991-09-02
AT351184B (de) 1979-07-10
FR2285866A1 (fr) 1976-04-23
KE2851A (en) 1978-07-21
US4361577A (en) 1982-11-30
FI63932C (fi) 1983-09-12
FI63932B (fi) 1983-05-31
IL48043A0 (en) 1975-11-25
DK390975A (da) 1976-03-26
DE2539116A1 (de) 1976-04-08
NO753028L (OSRAM) 1976-03-26
CH617186A5 (OSRAM) 1980-05-14
SU652889A3 (ru) 1979-03-15
ATA656075A (de) 1978-12-15
IL48043A (en) 1979-12-30
FR2378757A1 (fr) 1978-08-25
HU174287B (hu) 1979-12-28
FR2378757B1 (OSRAM) 1980-07-04
NO146357C (no) 1982-09-15
GB1483880A (en) 1977-08-24
NO146357B (no) 1982-06-07
CS191276B2 (en) 1979-06-29
JPS5918391B2 (ja) 1984-04-26
CY954A (en) 1978-12-22
IT1053781B (it) 1981-10-10
DK155316C (da) 1989-08-14
JPS51125044A (en) 1976-11-01
BE832983A (fr) 1976-03-02
FR2285866B1 (OSRAM) 1978-12-22
FI752491A7 (OSRAM) 1976-03-26
NL7510452A (nl) 1976-03-29
JPS5839156B2 (ja) 1983-08-27
DE2539116C2 (de) 1984-08-02
ZA755420B (en) 1977-04-27
JPS58135858A (ja) 1983-08-12
HK42478A (en) 1978-08-11
CA1083569A (en) 1980-08-12
DK155316B (da) 1989-03-28
SE7509764L (sv) 1976-03-26
MY7800321A (en) 1978-12-31
AU8381075A (en) 1977-02-10
US4035415A (en) 1977-07-12

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