SE411212B - Forfarande for framstellning av 3-halogen-cefalosporiner - Google Patents

Forfarande for framstellning av 3-halogen-cefalosporiner

Info

Publication number
SE411212B
SE411212B SE7402413A SE7402413A SE411212B SE 411212 B SE411212 B SE 411212B SE 7402413 A SE7402413 A SE 7402413A SE 7402413 A SE7402413 A SE 7402413A SE 411212 B SE411212 B SE 411212B
Authority
SE
Sweden
Prior art keywords
cephalosporine
halogen
procedure
preparation
Prior art date
Application number
SE7402413A
Other languages
English (en)
Swedish (sv)
Inventor
R R Chauvette
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE411212B publication Critical patent/SE411212B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE7402413A 1973-02-23 1974-02-22 Forfarande for framstellning av 3-halogen-cefalosporiner SE411212B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33538173A 1973-02-23 1973-02-23

Publications (1)

Publication Number Publication Date
SE411212B true SE411212B (sv) 1979-12-10

Family

ID=23311540

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7402413A SE411212B (sv) 1973-02-23 1974-02-22 Forfarande for framstellning av 3-halogen-cefalosporiner

Country Status (37)

Country Link
JP (4) JPS6139313B2 (ro)
AR (1) AR199510A1 (ro)
AT (1) AT333953B (ro)
BE (1) BE811495A (ro)
BR (1) BR7401384D0 (ro)
CA (1) CA1016537A (ro)
CH (1) CH593988A5 (ro)
CS (1) CS187409B2 (ro)
CY (1) CY1043A (ro)
DD (1) DD110278A5 (ro)
DE (1) DE2408698C2 (ro)
DK (1) DK153157C (ro)
EG (1) EG11104A (ro)
ES (1) ES423531A1 (ro)
FI (1) FI63035C (ro)
FR (1) FR2218877B1 (ro)
GB (1) GB1461323A (ro)
GT (1) GT197432133A (ro)
HK (1) HK20080A (ro)
HU (1) HU166849B (ro)
IE (1) IE39046B1 (ro)
IL (1) IL44262A (ro)
IN (1) IN139620B (ro)
KE (1) KE3027A (ro)
MW (1) MW674A1 (ro)
MY (1) MY8100024A (ro)
NL (1) NL179057C (ro)
NO (2) NO148375C (ro)
OA (1) OA04809A (ro)
PH (1) PH9616A (ro)
PL (1) PL88702B1 (ro)
RO (1) RO64663A (ro)
SE (1) SE411212B (ro)
SU (1) SU676166A3 (ro)
YU (1) YU36970B (ro)
ZA (1) ZA741191B (ro)
ZM (1) ZM3574A1 (ro)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
CH619233A5 (ro) * 1975-07-31 1980-09-15 Ciba Geigy Ag
CH622802A5 (ro) * 1975-08-20 1981-04-30 Ciba Geigy Ag
IE45158B1 (en) * 1976-08-16 1982-06-30 Lilly Co Eli 3-chloro-cephem synthesis
DE3508258A1 (de) * 1985-03-08 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zur herstellung und ihre verwendung als und in arzneimitteln
DE3509618A1 (de) 1985-03-16 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactam-antibiotika, verfahren zur herstellung und ihre verwendung als arzneimittel
JPS6436445U (ro) * 1987-08-28 1989-03-06
DE3803169A1 (de) 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln
ES2010075A6 (es) * 1989-01-10 1989-10-16 Antibioticos Sa Un procedimiento para la preparacion de compuestos de 3-cloro-cefem.
JP2539459Y2 (ja) * 1991-12-18 1997-06-25 三重ホーロー株式会社 組立式塵芥焼却器
IT1255458B (it) * 1992-05-11 1995-11-02 Col Marco Da Procedimento per la preparazione di derivati beta-lattamici alogenati
ES2079327B1 (es) 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
CN101805357B (zh) * 2010-04-28 2012-01-11 陶灵刚 一种头孢克洛化合物及其制法
CN103588790A (zh) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法
CN106632400A (zh) * 2016-12-16 2017-05-10 石家庄柏奇化工有限公司 Pd‑C催化氢化脱除4‑硝基苄基制备7‑ACCA的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
DE2265798C2 (de) * 1971-06-24 1985-09-26 Fujisawa Pharmaceutical Co., Ltd., Osaka Verfahren zur Herstellung von Oxoazetidin-Derivaten
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos

Also Published As

Publication number Publication date
NO148377B (no) 1983-06-20
JPS6140237B2 (ro) 1986-09-08
CA1016537A (en) 1977-08-30
AT333953B (de) 1976-12-27
PH9616A (en) 1976-01-20
FI63035B (fi) 1982-12-31
CS187409B2 (en) 1979-01-31
NO148377C (no) 1983-09-28
JPS6140235B2 (ro) 1986-09-08
YU36970B (en) 1984-08-31
IN139620B (ro) 1976-07-10
EG11104A (en) 1976-12-31
PL88702B1 (ro) 1976-09-30
SU676166A3 (ru) 1979-07-25
DE2408698A1 (de) 1974-09-05
IL44262A0 (en) 1974-05-16
JPS56138190A (en) 1981-10-28
CY1043A (en) 1980-08-01
CH593988A5 (ro) 1977-12-30
IE39046B1 (en) 1978-07-19
FR2218877B1 (ro) 1977-03-11
JPS56138192A (en) 1981-10-28
ATA142574A (de) 1976-04-15
JPS56138191A (en) 1981-10-28
JPS6139313B2 (ro) 1986-09-03
OA04809A (fr) 1980-08-31
IE39046L (en) 1974-08-23
JPS49110689A (ro) 1974-10-22
AU6591674A (en) 1975-08-28
NO148375C (no) 1983-09-28
AR199510A1 (es) 1974-09-09
MY8100024A (en) 1981-12-31
NL179057B (nl) 1986-02-03
NO740606L (no) 1974-08-26
RO64663A (fr) 1979-02-15
HU166849B (ro) 1975-06-28
DK153157C (da) 1988-10-31
FR2218877A1 (ro) 1974-09-20
ZA741191B (en) 1975-10-29
KE3027A (en) 1980-03-14
MW674A1 (en) 1975-04-09
DK153157B (da) 1988-06-20
ZM3574A1 (en) 1975-11-21
FI63035C (fi) 1983-04-11
DE2408698C2 (de) 1983-11-10
NO792681L (no) 1974-08-26
ES423531A1 (es) 1976-05-16
HK20080A (en) 1980-04-25
JPS6140236B2 (ro) 1986-09-08
GT197432133A (es) 1975-08-16
GB1461323A (en) 1977-01-13
NL179057C (nl) 1986-07-01
NO148375B (no) 1983-06-20
IL44262A (en) 1977-08-31
YU39974A (en) 1982-06-18
BE811495A (fr) 1974-08-22
NL7402489A (ro) 1974-08-27
BR7401384D0 (pt) 1974-11-05
DD110278A5 (ro) 1974-12-12

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