SE407571B - Nya kromogena enzymsubstrat for serinproteaser - Google Patents
Nya kromogena enzymsubstrat for serinproteaserInfo
- Publication number
- SE407571B SE407571B SE7507974A SE7507974A SE407571B SE 407571 B SE407571 B SE 407571B SE 7507974 A SE7507974 A SE 7507974A SE 7507974 A SE7507974 A SE 7507974A SE 407571 B SE407571 B SE 407571B
- Authority
- SE
- Sweden
- Prior art keywords
- substrates
- group
- omm
- reaction
- pna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/10—Anilides
- C12Q2337/12—Para-Nitroanilides p-NA
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7507974A SE407571B (sv) | 1975-07-11 | 1975-07-11 | Nya kromogena enzymsubstrat for serinproteaser |
ZA763585A ZA763585B (en) | 1975-07-11 | 1976-06-16 | Novel chromogenic enzyme substrates |
IL49830A IL49830A (en) | 1975-07-11 | 1976-06-17 | Chromogenic enzyme substrates |
GB25411/76A GB1510925A (en) | 1975-07-11 | 1976-06-18 | Chromogenic enzyme substrates |
AT464076A AT349648B (de) | 1975-07-11 | 1976-06-25 | Verfahren zur bestimmung von enzymen des typus serinproteasen, bei dem aminosaeurereste ent- haltende chromogene substrate durch diese enzyme gespalten werden |
AU15304/76A AU497546B2 (en) | 1975-07-11 | 1976-06-25 | Chromogenic enzyme substrate |
DE19762629067 DE2629067A1 (de) | 1975-07-11 | 1976-06-29 | Chromogene enzymsubstrate |
NLAANVRAGE7607433,A NL187693C (nl) | 1975-07-11 | 1976-07-06 | Werkwijze ter bereiding van een diagnostisch actief chromogeen substraat. |
CS764543A CS199631B2 (en) | 1975-07-11 | 1976-07-08 | Method of producing new chromogen enzyme substrate |
PL1976191067A PL103098B1 (pl) | 1975-07-11 | 1976-07-09 | Sposob wytwarzania nowych chromogennych odczynnikow diagnostycznych do oznaczania enzymow |
FI762009A FI56524C (fi) | 1975-07-11 | 1976-07-09 | Nya komogena substrat foer serinproteaser |
IT50363/76A IT1062604B (it) | 1975-07-11 | 1976-07-09 | Substrato enzimatico cromogeno |
DK312776A DK146937C (da) | 1975-07-11 | 1976-07-09 | Tripeptider eller salte deraf til anvendelse som diagnostisk kromogent substrat for serinproteaser |
FR7621195A FR2317278A1 (fr) | 1975-07-11 | 1976-07-09 | Nouveaux substrats enzymatiques chromogenes |
CH887176A CH622285A5 (no) | 1975-07-11 | 1976-07-09 | |
CA256,705A CA1081212A (en) | 1975-07-11 | 1976-07-09 | Chromogenic enzyme substrates |
NO762406A NO142812C (no) | 1975-07-11 | 1976-07-09 | Nye diagnostisk aktive kromogene enzymsubstrater |
BE168773A BE843969A (fr) | 1975-07-11 | 1976-07-09 | Nouveaux substrats chromogenes d'enzymes |
SU762379653A SU700060A3 (ru) | 1975-07-11 | 1976-07-09 | Способ получени пептидов или их солей |
DD193794A DD127320A5 (no) | 1975-07-11 | 1976-07-09 | |
ES449738A ES449738A1 (es) | 1975-07-11 | 1976-07-09 | Procedimiento de obtencion de nuevos sustratos de enzimas cromogenicas. |
JP51082441A JPS5224581A (en) | 1975-07-11 | 1976-07-10 | Novel colorrproducing enzymatic substrate |
US05/888,586 US4137225A (en) | 1975-07-11 | 1978-03-20 | Novel chromogenic enzyme substrates |
US05/955,441 US4214049A (en) | 1975-07-11 | 1978-10-27 | Assay of serine proteases using novel chromogenic enzyme substrates |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7507974A SE407571B (sv) | 1975-07-11 | 1975-07-11 | Nya kromogena enzymsubstrat for serinproteaser |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7507974L SE7507974L (sv) | 1977-01-12 |
SE407571B true SE407571B (sv) | 1979-04-02 |
Family
ID=20325115
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7507974A SE407571B (sv) | 1975-07-11 | 1975-07-11 | Nya kromogena enzymsubstrat for serinproteaser |
Country Status (23)
Country | Link |
---|---|
US (1) | US4214049A (no) |
JP (1) | JPS5224581A (no) |
AT (1) | AT349648B (no) |
AU (1) | AU497546B2 (no) |
BE (1) | BE843969A (no) |
CA (1) | CA1081212A (no) |
CH (1) | CH622285A5 (no) |
CS (1) | CS199631B2 (no) |
DD (1) | DD127320A5 (no) |
DE (1) | DE2629067A1 (no) |
DK (1) | DK146937C (no) |
ES (1) | ES449738A1 (no) |
FI (1) | FI56524C (no) |
FR (1) | FR2317278A1 (no) |
GB (1) | GB1510925A (no) |
IL (1) | IL49830A (no) |
IT (1) | IT1062604B (no) |
NL (1) | NL187693C (no) |
NO (1) | NO142812C (no) |
PL (1) | PL103098B1 (no) |
SE (1) | SE407571B (no) |
SU (1) | SU700060A3 (no) |
ZA (1) | ZA763585B (no) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1980000252A1 (en) * | 1978-07-18 | 1980-02-21 | Kabi Ab | Bradykinin-inhibiting tripeptide derivatives |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH634662A5 (de) * | 1976-05-28 | 1983-02-15 | Pentapharm Ag | Verwendung von tripeptidderivaten zur quantitativen bestimmung von plasminogen-aktivatoren. |
SE7801373L (sv) * | 1978-02-07 | 1979-08-08 | Kabi Ab | Lett spjelkbara substrat for kvantifiering av proteaser |
US4275153A (en) * | 1978-08-03 | 1981-06-23 | American Hospital Supply Corporation | Analytical fluorogenic substrates for proteolytic enzymes |
JPS5537120A (en) * | 1978-09-06 | 1980-03-15 | Kanji Tsuchiya | Method and device for preparation of food from oilseed |
JPS5559149A (en) * | 1978-10-30 | 1980-05-02 | Torii Yakuhin Kk | Aminoacid derivative |
JPS59499B2 (ja) * | 1978-11-02 | 1984-01-07 | 味の素株式会社 | ペプチド誘導体 |
US4327178A (en) | 1979-05-01 | 1982-04-27 | University Of Miami | Urinary kallikrein assay: specific substrates and assay method |
CA1161431A (en) * | 1979-05-11 | 1984-01-31 | Lars G. Svendsen | Tripeptide derivatives |
DE2936543A1 (de) * | 1979-09-10 | 1981-04-09 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen |
CA1161432A (en) * | 1980-02-12 | 1984-01-31 | Lars G. Svendsen | Tripeptide derivatives and their application in assaying enzymes |
DE3108322A1 (de) | 1980-03-18 | 1981-12-24 | Immuno Aktiengesellschaft für chemisch-medizinische Produkte, 1220 Wien | Chromogenes enzymsubstrat |
DK155051C (da) * | 1980-05-06 | 1989-07-03 | Pentapharm Ag | Tripeptidderivater samt fremgangsmaade til kvantitativ analyse for proteolytiske enzymer under anvendelse deraf |
US4568636A (en) * | 1981-03-25 | 1986-02-04 | Pentapharm Ag | Tripeptide derivatives |
JPS57177985U (no) * | 1981-04-30 | 1982-11-11 | ||
US4510241A (en) * | 1981-09-03 | 1985-04-09 | Mallinckrodt, Inc. | Peptide-type substrates useful in the quantitative determination of endotoxin |
US4406832A (en) * | 1981-09-03 | 1983-09-27 | Mallinckrodt, Inc. | Peptide-type substrates useful in the quantitative determination of endotoxin |
JPS5863399A (ja) * | 1981-10-14 | 1983-04-15 | Nitto Boseki Co Ltd | 新規なプラスミン測定用基質 |
DE3268329D1 (en) * | 1981-11-02 | 1986-02-13 | Pentapharm Ag | Process for the quantitative determination of the blood clotting factor xii in human plasma |
US4448715A (en) * | 1981-11-02 | 1984-05-15 | University Of Miami | Tagged pyroglu-L-Phe-L-Arg derivatives, substrates and assays for kallikrein |
NL8201987A (nl) * | 1982-05-13 | 1983-12-01 | Tno | Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type. |
DE3244030A1 (de) * | 1982-11-27 | 1984-05-30 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung |
DK201084A (da) * | 1983-04-28 | 1984-10-29 | Kimberly Clark Co | Fremgangsmaade til bestemmelse af cathepsin b i naervaerelse af andre proteolytiske enzymer, og forbindelser til anvendelse ved fremgangsmaaden |
EP0182929A1 (de) * | 1984-11-26 | 1986-06-04 | American Hospital Supply Corporation | Koaktivator zur Aktivierung von Protein C |
DE3536903A1 (de) * | 1985-10-16 | 1987-04-16 | Boehringer Mannheim Gmbh | Verfahren zur photometrischen bestimmung von protein c |
JPS62126196A (ja) * | 1985-11-26 | 1987-06-08 | Nitto Boseki Co Ltd | 新規なα1−アンチトリプシン測定用化合物 |
DE3710937A1 (de) * | 1987-04-01 | 1988-10-13 | Boehringer Mannheim Gmbh | Chromogene verbindungen, ihre herstellung und verwendung als enzymsubstrate |
JPH01112157A (ja) * | 1987-07-10 | 1989-04-28 | Yamanouchi Pharmaceut Co Ltd | 組織プラスミノーゲンアクチベーター活性の測定法,測定具及び測定用キット |
JPH0383093U (no) * | 1989-12-09 | 1991-08-23 | ||
EP0802986B1 (en) | 1995-01-10 | 2001-09-19 | Hendrik Coenraad Hemker | Methods of determining endogenous thrombin potential (etp) and thrombin substrates for use in said methods |
CN114341154B (zh) * | 2019-09-05 | 2024-07-30 | 国立大学法人东京农工大学 | 类胰蛋白酶活性测定用底物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE380258B (sv) * | 1972-05-02 | 1975-11-03 | Bofors Ab | Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser |
SE380257B (sv) * | 1972-05-02 | 1975-11-03 | Bofors Ab | Nya diagnostiskt verksamma substrat med hog specificitet till trombin och andra proteolytiska enzymer av typen peptidyl-peptid-hydrolaser |
DE2527932C2 (de) * | 1974-07-02 | 1983-04-21 | Pentapharm AG, 4052 Basel | Säureadditionssalze von Tripeptidderivaten und deren Verwendung als Substrate zur Bestimmung von Plasmakallikrein |
SE407058B (sv) * | 1974-12-05 | 1979-03-12 | Kabi Ab | Nya kromogena enzymsubstrat for serinproteaser |
CH622286A5 (no) * | 1975-06-23 | 1981-03-31 | Pentapharm Ag |
-
1975
- 1975-07-11 SE SE7507974A patent/SE407571B/sv not_active IP Right Cessation
-
1976
- 1976-06-16 ZA ZA763585A patent/ZA763585B/xx unknown
- 1976-06-17 IL IL49830A patent/IL49830A/xx unknown
- 1976-06-18 GB GB25411/76A patent/GB1510925A/en not_active Expired
- 1976-06-25 AU AU15304/76A patent/AU497546B2/en not_active Expired
- 1976-06-25 AT AT464076A patent/AT349648B/de not_active IP Right Cessation
- 1976-06-29 DE DE19762629067 patent/DE2629067A1/de active Granted
- 1976-07-06 NL NLAANVRAGE7607433,A patent/NL187693C/xx not_active IP Right Cessation
- 1976-07-08 CS CS764543A patent/CS199631B2/cs unknown
- 1976-07-09 DK DK312776A patent/DK146937C/da not_active IP Right Cessation
- 1976-07-09 DD DD193794A patent/DD127320A5/xx unknown
- 1976-07-09 NO NO762406A patent/NO142812C/no unknown
- 1976-07-09 CA CA256,705A patent/CA1081212A/en not_active Expired
- 1976-07-09 ES ES449738A patent/ES449738A1/es not_active Expired
- 1976-07-09 BE BE168773A patent/BE843969A/xx not_active IP Right Cessation
- 1976-07-09 CH CH887176A patent/CH622285A5/de not_active IP Right Cessation
- 1976-07-09 SU SU762379653A patent/SU700060A3/ru active
- 1976-07-09 PL PL1976191067A patent/PL103098B1/pl unknown
- 1976-07-09 FI FI762009A patent/FI56524C/fi not_active IP Right Cessation
- 1976-07-09 IT IT50363/76A patent/IT1062604B/it active
- 1976-07-09 FR FR7621195A patent/FR2317278A1/fr active Granted
- 1976-07-10 JP JP51082441A patent/JPS5224581A/ja active Granted
-
1978
- 1978-10-27 US US05/955,441 patent/US4214049A/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1980000252A1 (en) * | 1978-07-18 | 1980-02-21 | Kabi Ab | Bradykinin-inhibiting tripeptide derivatives |
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