SE390414B - 14,15-dioxo-e-homo-eburnaner som mellanprodukt for framstellning av vinkamin - Google Patents

14,15-dioxo-e-homo-eburnaner som mellanprodukt for framstellning av vinkamin

Info

Publication number
SE390414B
SE390414B SE7405749A SE574974A SE390414B SE 390414 B SE390414 B SE 390414B SE 7405749 A SE7405749 A SE 7405749A SE 574974 A SE574974 A SE 574974A SE 390414 B SE390414 B SE 390414B
Authority
SE
Sweden
Prior art keywords
vinkamine
eburnanes
dioxo
homo
intermediate production
Prior art date
Application number
SE7405749A
Other languages
English (en)
Swedish (sv)
Inventor
J Warnant
A Farcilli
E Toromanoff
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7011406A external-priority patent/FR2081593A1/fr
Priority claimed from FR7032889A external-priority patent/FR2104959A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of SE390414B publication Critical patent/SE390414B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
SE7405749A 1970-03-31 1971-03-31 14,15-dioxo-e-homo-eburnaner som mellanprodukt for framstellning av vinkamin SE390414B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7011406A FR2081593A1 (en) 1970-03-31 1970-03-31 Vincamine process
FR7032889A FR2104959A2 (en) 1970-09-10 1970-09-10 Vincamine process

Publications (1)

Publication Number Publication Date
SE390414B true SE390414B (sv) 1976-12-20

Family

ID=26215644

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7405749A SE390414B (sv) 1970-03-31 1971-03-31 14,15-dioxo-e-homo-eburnaner som mellanprodukt for framstellning av vinkamin
SE7104214A SE386179B (sv) 1970-03-31 1971-03-31 Sett att framstella vinkamin.

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7104214A SE386179B (sv) 1970-03-31 1971-03-31 Sett att framstella vinkamin.

Country Status (16)

Country Link
US (1) US3770724A (xx)
JP (3) JPS5144960B1 (xx)
AT (1) AT309699B (xx)
BE (1) BE765006A (xx)
CA (1) CA937570A (xx)
CH (1) CH546777A (xx)
DE (3) DE2167043A1 (xx)
DK (1) DK149345C (xx)
GB (3) GB1351262A (xx)
HU (1) HU163769B (xx)
IL (1) IL36474A (xx)
IT (1) IT8048032A0 (xx)
NL (1) NL158497B (xx)
PL (1) PL83152B1 (xx)
SE (2) SE390414B (xx)
SU (1) SU505365A3 (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL153199B (nl) * 1971-10-25 1977-05-16 Omnium Chimique Sa Werkwijze voor de bereiding van esters van vincaminezuur, alsmede werkwijze voor de bereiding van een geneesmiddel dat een dergelijke ester bevat en gevormd geneesmiddel dat aldus is verkregen.
CH578001A5 (xx) * 1972-04-14 1976-07-30 Sandoz Ag
FR2179620B1 (xx) * 1972-04-14 1975-12-26 Roussel Uclaf
US4033969A (en) * 1972-06-19 1977-07-05 Agence Nationale De Valorisation De La Recherche (Anvar) Vincamine derivatives
FR2259612B1 (xx) * 1974-01-31 1977-09-09 Synthelabo
CH625239A5 (xx) * 1974-08-09 1981-09-15 Buskine Sa
JPS536264U (xx) * 1976-06-30 1978-01-20
HU174502B (hu) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina
FR2445328A1 (fr) * 1978-07-12 1980-07-25 Richter Gedeon Vegyeszet Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
US4428877A (en) 1978-07-12 1984-01-31 Richter Gedeon Vegyeszeti Gyar Rt. Cis-10-bromo-E-homoeburnanes
US4316028A (en) * 1978-11-20 1982-02-16 Sumitomo Chemical Company, Limited Process for producing eburnane derivatives
AU532001B2 (en) * 1978-11-20 1983-09-15 Sumitomo Chemical Company, Limited Polycyclic indole derivatives
HU179292B (en) * 1978-12-01 1982-09-28 Richter Gedeon Vegyeszet Process for preparing ester derivatives of apovincaminic acid
HU180928B (en) * 1979-08-06 1983-05-30 Richter Gedeon Vegyeszet Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives
HU181496B (en) * 1979-08-13 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes
JPS5689589U (xx) * 1979-12-13 1981-07-17
JPS5693693U (xx) * 1979-12-14 1981-07-25
HU185305B (en) * 1981-08-23 1985-01-28 Richter Gedeon Vegyeszet Process for preparing vincine and apovincine
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
JPS59258U (ja) * 1982-06-24 1984-01-05 日本ピラ−工業株式会社 平板形電子管式表示装置
HU187733B (en) * 1982-06-30 1986-02-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing apovincaminic acid derivatives
HU187139B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new eburnan derivatives
HU187140B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new aburnan-oxima ethers
JPS59105767U (ja) * 1983-01-06 1984-07-16 日本ピラ−工業株式会社 平板形電子管式表示装置
JPS6032240A (ja) * 1983-07-30 1985-02-19 Sony Corp 螢光表示装置
GEP20074134B (en) 2002-08-19 2007-06-25 Pfizer Prod Inc Combination therapy for hyperproliferative diseases
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها
CN111205288B (zh) * 2020-02-19 2021-03-30 四川大学 一种(1S,12bS)内酰胺酯化合物的合成方法

Also Published As

Publication number Publication date
BE765006A (fr) 1971-09-30
CH546777A (fr) 1974-03-15
DE2167043A1 (de) 1977-10-13
IT8048032A0 (it) 1980-02-28
DK149345C (da) 1986-10-13
JPS5337360B2 (xx) 1978-10-07
DE2167044C2 (de) 1983-07-14
US3770724A (en) 1973-11-06
DE2167044A1 (de) 1977-11-10
DE2115718A1 (de) 1971-10-14
CA937570A (en) 1973-11-27
JPS5227160B2 (xx) 1977-07-19
NL7104275A (xx) 1971-10-04
DE2115718B2 (de) 1978-11-02
GB1351263A (en) 1974-04-24
NL158497B (nl) 1978-11-15
IL36474A (en) 1975-08-31
GB1351261A (en) 1974-04-24
JPS5144960B1 (xx) 1976-12-01
SE386179B (sv) 1976-08-02
PL83152B1 (en) 1975-12-31
GB1351262A (en) 1974-04-24
JPS5163197A (xx) 1976-06-01
SU505365A3 (ru) 1976-02-28
IL36474A0 (en) 1971-05-26
DE2115718C3 (de) 1979-07-19
JPS5163198A (xx) 1976-06-01
DK149345B (da) 1986-05-12
AT309699B (de) 1973-07-15
HU163769B (xx) 1973-10-27

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