IL36474A - Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes - Google Patents
Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanesInfo
- Publication number
- IL36474A IL36474A IL36474A IL3647471A IL36474A IL 36474 A IL36474 A IL 36474A IL 36474 A IL36474 A IL 36474A IL 3647471 A IL3647471 A IL 3647471A IL 36474 A IL36474 A IL 36474A
- Authority
- IL
- Israel
- Prior art keywords
- homoeburnanes
- eburnamonine
- vincamine
- preparing
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7011406A FR2081593A1 (en) | 1970-03-31 | 1970-03-31 | Vincamine process |
FR7032889A FR2104959A2 (en) | 1970-09-10 | 1970-09-10 | Vincamine process |
Publications (2)
Publication Number | Publication Date |
---|---|
IL36474A0 IL36474A0 (en) | 1971-05-26 |
IL36474A true IL36474A (en) | 1975-08-31 |
Family
ID=26215644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL36474A IL36474A (en) | 1970-03-31 | 1971-03-23 | Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes |
Country Status (16)
Country | Link |
---|---|
US (1) | US3770724A (en) |
JP (3) | JPS5144960B1 (en) |
AT (1) | AT309699B (en) |
BE (1) | BE765006A (en) |
CA (1) | CA937570A (en) |
CH (1) | CH546777A (en) |
DE (3) | DE2115718C3 (en) |
DK (1) | DK149345C (en) |
GB (3) | GB1351262A (en) |
HU (1) | HU163769B (en) |
IL (1) | IL36474A (en) |
IT (1) | IT8048032A0 (en) |
NL (1) | NL158497B (en) |
PL (1) | PL83152B1 (en) |
SE (2) | SE390414B (en) |
SU (1) | SU505365A3 (en) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL153199B (en) * | 1971-10-25 | 1977-05-16 | Omnium Chimique Sa | PROCESS FOR THE PREPARATION OF VINCAMIC ACID ESTERS AND PROCEDURE FOR THE PREPARATION OF A MEDICINAL PRODUCT CONTAINING SUCH ESTER AND FORMED MEDICINAL PRODUCT THEREFORE OBTAINED. |
CH578001A5 (en) * | 1972-04-14 | 1976-07-30 | Sandoz Ag | |
FR2179620B1 (en) * | 1972-04-14 | 1975-12-26 | Roussel Uclaf | |
US4033969A (en) * | 1972-06-19 | 1977-07-05 | Agence Nationale De Valorisation De La Recherche (Anvar) | Vincamine derivatives |
FR2259612B1 (en) * | 1974-01-31 | 1977-09-09 | Synthelabo | |
CH625239A5 (en) * | 1974-08-09 | 1981-09-15 | Buskine Sa | |
JPS536264U (en) * | 1976-06-30 | 1978-01-20 | ||
HU174502B (en) * | 1976-12-30 | 1980-01-28 | Richter Gedeon Vegyeszet | Process for preparing new octahydro-indolo/2,3-a/quinolizine derivatives |
US4315011A (en) * | 1978-07-12 | 1982-02-09 | Richter Gedeon Vegyeszeti Gyar Rt. | 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow |
US4428877A (en) | 1978-07-12 | 1984-01-31 | Richter Gedeon Vegyeszeti Gyar Rt. | Cis-10-bromo-E-homoeburnanes |
FR2445328A1 (en) * | 1978-07-12 | 1980-07-25 | Richter Gedeon Vegyeszet | DERIVATIVES OF 14-OXO-E-HOMO-EBURNANE, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENT |
US4316028A (en) * | 1978-11-20 | 1982-02-16 | Sumitomo Chemical Company, Limited | Process for producing eburnane derivatives |
AU532001B2 (en) * | 1978-11-20 | 1983-09-15 | Sumitomo Chemical Company, Limited | Polycyclic indole derivatives |
HU179292B (en) * | 1978-12-01 | 1982-09-28 | Richter Gedeon Vegyeszet | Process for preparing ester derivatives of apovincaminic acid |
HU180928B (en) * | 1979-08-06 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives |
HU181496B (en) * | 1979-08-13 | 1983-07-28 | Richter Gedeon Vegyeszet | Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes |
JPS5689589U (en) * | 1979-12-13 | 1981-07-17 | ||
JPS5693693U (en) * | 1979-12-14 | 1981-07-25 | ||
HU185305B (en) * | 1981-08-23 | 1985-01-28 | Richter Gedeon Vegyeszet | Process for preparing vincine and apovincine |
HU183234B (en) * | 1980-10-17 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan |
HU182411B (en) * | 1981-11-03 | 1984-01-30 | Richter Gedeon Vegyeszet | Process for preparing eburnamonine derivatives |
HU186891B (en) * | 1981-06-12 | 1985-10-28 | Richter Gedeon Vegyeszet | Process for producing esters of apovincaminic acid |
HU182380B (en) * | 1981-09-30 | 1983-12-28 | Richter Gedeon Vegyeszet | Process for producing esters of vincaminic acid |
JPS59258U (en) * | 1982-06-24 | 1984-01-05 | 日本ピラ−工業株式会社 | Flat type electron tube display device |
HU187140B (en) * | 1982-06-30 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for preparing new aburnan-oxima ethers |
HU187139B (en) * | 1982-06-30 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for preparing new eburnan derivatives |
HU187733B (en) * | 1982-06-30 | 1986-02-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing apovincaminic acid derivatives |
JPS59105767U (en) * | 1983-01-06 | 1984-07-16 | 日本ピラ−工業株式会社 | Flat type electron tube display device |
JPS6032240A (en) * | 1983-07-30 | 1985-02-19 | Sony Corp | Phosphor display device |
MXPA05001958A (en) | 2002-08-19 | 2005-04-28 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
CN101663262B (en) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
CN105143203A (en) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055B (en) | 2019-01-18 | 2024-07-23 | 阿斯利康(瑞典)有限公司 | PCSK9 inhibitors and methods of use thereof |
CN111205288B (en) * | 2020-02-19 | 2021-03-30 | 四川大学 | Synthesis method of (1S,12bS) lactam ester compound |
-
1971
- 1971-03-22 US US00126929A patent/US3770724A/en not_active Expired - Lifetime
- 1971-03-23 CH CH422071A patent/CH546777A/en not_active IP Right Cessation
- 1971-03-23 PL PL1971147087A patent/PL83152B1/en unknown
- 1971-03-23 IL IL36474A patent/IL36474A/en unknown
- 1971-03-25 HU HURO609A patent/HU163769B/hu unknown
- 1971-03-30 BE BE765006A patent/BE765006A/en not_active IP Right Cessation
- 1971-03-30 CA CA109157A patent/CA937570A/en not_active Expired
- 1971-03-30 SU SU711633905A patent/SU505365A3/en active
- 1971-03-31 DE DE2115718A patent/DE2115718C3/en not_active Expired
- 1971-03-31 NL NL7104275.A patent/NL158497B/en not_active IP Right Cessation
- 1971-03-31 AT ATA2739/71A patent/AT309699B/en not_active IP Right Cessation
- 1971-03-31 DK DK153171A patent/DK149345C/en not_active IP Right Cessation
- 1971-03-31 DE DE19712167043 patent/DE2167043A1/en not_active Ceased
- 1971-03-31 SE SE7405749A patent/SE390414B/en not_active IP Right Cessation
- 1971-03-31 JP JP46018828A patent/JPS5144960B1/ja active Pending
- 1971-03-31 DE DE2167044A patent/DE2167044C2/en not_active Expired
- 1971-03-31 SE SE7104214A patent/SE386179B/en unknown
- 1971-04-19 GB GB2578671*A patent/GB1351262A/en not_active Expired
- 1971-04-19 GB GB2578671*A patent/GB1351261A/en not_active Expired
- 1971-04-19 GB GB2578671*A patent/GB1351263A/en not_active Expired
-
1975
- 1975-10-15 JP JP50123333A patent/JPS5227160B2/ja not_active Expired
- 1975-10-15 JP JP12333275A patent/JPS5337360B2/ja not_active Expired
-
1980
- 1980-02-28 IT IT8048032A patent/IT8048032A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
SE390414B (en) | 1976-12-20 |
US3770724A (en) | 1973-11-06 |
HU163769B (en) | 1973-10-27 |
CA937570A (en) | 1973-11-27 |
DE2167044A1 (en) | 1977-11-10 |
DE2115718C3 (en) | 1979-07-19 |
DE2115718A1 (en) | 1971-10-14 |
JPS5163197A (en) | 1976-06-01 |
DK149345C (en) | 1986-10-13 |
JPS5227160B2 (en) | 1977-07-19 |
IL36474A0 (en) | 1971-05-26 |
DK149345B (en) | 1986-05-12 |
BE765006A (en) | 1971-09-30 |
NL158497B (en) | 1978-11-15 |
IT8048032A0 (en) | 1980-02-28 |
AT309699B (en) | 1973-07-15 |
SE386179B (en) | 1976-08-02 |
JPS5163198A (en) | 1976-06-01 |
JPS5337360B2 (en) | 1978-10-07 |
CH546777A (en) | 1974-03-15 |
NL7104275A (en) | 1971-10-04 |
GB1351263A (en) | 1974-04-24 |
GB1351262A (en) | 1974-04-24 |
DE2115718B2 (en) | 1978-11-02 |
SU505365A3 (en) | 1976-02-28 |
GB1351261A (en) | 1974-04-24 |
JPS5144960B1 (en) | 1976-12-01 |
DE2167043A1 (en) | 1977-10-13 |
PL83152B1 (en) | 1975-12-31 |
DE2167044C2 (en) | 1983-07-14 |
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