IL36474A - Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes - Google Patents

Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes

Info

Publication number
IL36474A
IL36474A IL36474A IL3647471A IL36474A IL 36474 A IL36474 A IL 36474A IL 36474 A IL36474 A IL 36474A IL 3647471 A IL3647471 A IL 3647471A IL 36474 A IL36474 A IL 36474A
Authority
IL
Israel
Prior art keywords
homoeburnanes
eburnamonine
vincamine
preparing
novel
Prior art date
Application number
IL36474A
Other versions
IL36474A0 (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7011406A external-priority patent/FR2081593A1/en
Priority claimed from FR7032889A external-priority patent/FR2104959A2/en
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IL36474A0 publication Critical patent/IL36474A0/en
Publication of IL36474A publication Critical patent/IL36474A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL36474A 1970-03-31 1971-03-23 Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes IL36474A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7011406A FR2081593A1 (en) 1970-03-31 1970-03-31 Vincamine process
FR7032889A FR2104959A2 (en) 1970-09-10 1970-09-10 Vincamine process

Publications (2)

Publication Number Publication Date
IL36474A0 IL36474A0 (en) 1971-05-26
IL36474A true IL36474A (en) 1975-08-31

Family

ID=26215644

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36474A IL36474A (en) 1970-03-31 1971-03-23 Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes

Country Status (16)

Country Link
US (1) US3770724A (en)
JP (3) JPS5144960B1 (en)
AT (1) AT309699B (en)
BE (1) BE765006A (en)
CA (1) CA937570A (en)
CH (1) CH546777A (en)
DE (3) DE2115718C3 (en)
DK (1) DK149345C (en)
GB (3) GB1351262A (en)
HU (1) HU163769B (en)
IL (1) IL36474A (en)
IT (1) IT8048032A0 (en)
NL (1) NL158497B (en)
PL (1) PL83152B1 (en)
SE (2) SE390414B (en)
SU (1) SU505365A3 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL153199B (en) * 1971-10-25 1977-05-16 Omnium Chimique Sa PROCESS FOR THE PREPARATION OF VINCAMIC ACID ESTERS AND PROCEDURE FOR THE PREPARATION OF A MEDICINAL PRODUCT CONTAINING SUCH ESTER AND FORMED MEDICINAL PRODUCT THEREFORE OBTAINED.
CH578001A5 (en) * 1972-04-14 1976-07-30 Sandoz Ag
FR2179620B1 (en) * 1972-04-14 1975-12-26 Roussel Uclaf
US4033969A (en) * 1972-06-19 1977-07-05 Agence Nationale De Valorisation De La Recherche (Anvar) Vincamine derivatives
FR2259612B1 (en) * 1974-01-31 1977-09-09 Synthelabo
CH625239A5 (en) * 1974-08-09 1981-09-15 Buskine Sa
JPS536264U (en) * 1976-06-30 1978-01-20
HU174502B (en) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Process for preparing new octahydro-indolo/2,3-a/quinolizine derivatives
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
US4428877A (en) 1978-07-12 1984-01-31 Richter Gedeon Vegyeszeti Gyar Rt. Cis-10-bromo-E-homoeburnanes
FR2445328A1 (en) * 1978-07-12 1980-07-25 Richter Gedeon Vegyeszet DERIVATIVES OF 14-OXO-E-HOMO-EBURNANE, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENT
US4316028A (en) * 1978-11-20 1982-02-16 Sumitomo Chemical Company, Limited Process for producing eburnane derivatives
AU532001B2 (en) * 1978-11-20 1983-09-15 Sumitomo Chemical Company, Limited Polycyclic indole derivatives
HU179292B (en) * 1978-12-01 1982-09-28 Richter Gedeon Vegyeszet Process for preparing ester derivatives of apovincaminic acid
HU180928B (en) * 1979-08-06 1983-05-30 Richter Gedeon Vegyeszet Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives
HU181496B (en) * 1979-08-13 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes
JPS5689589U (en) * 1979-12-13 1981-07-17
JPS5693693U (en) * 1979-12-14 1981-07-25
HU185305B (en) * 1981-08-23 1985-01-28 Richter Gedeon Vegyeszet Process for preparing vincine and apovincine
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
JPS59258U (en) * 1982-06-24 1984-01-05 日本ピラ−工業株式会社 Flat type electron tube display device
HU187140B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new aburnan-oxima ethers
HU187139B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new eburnan derivatives
HU187733B (en) * 1982-06-30 1986-02-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing apovincaminic acid derivatives
JPS59105767U (en) * 1983-01-06 1984-07-16 日本ピラ−工業株式会社 Flat type electron tube display device
JPS6032240A (en) * 1983-07-30 1985-02-19 Sony Corp Phosphor display device
MXPA05001958A (en) 2002-08-19 2005-04-28 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
CN101663262B (en) 2006-12-01 2014-03-26 百时美施贵宝公司 N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
CN105143203A (en) 2013-04-17 2015-12-09 辉瑞大药厂 N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN113574055B (en) 2019-01-18 2024-07-23 阿斯利康(瑞典)有限公司 PCSK9 inhibitors and methods of use thereof
CN111205288B (en) * 2020-02-19 2021-03-30 四川大学 Synthesis method of (1S,12bS) lactam ester compound

Also Published As

Publication number Publication date
SE390414B (en) 1976-12-20
US3770724A (en) 1973-11-06
HU163769B (en) 1973-10-27
CA937570A (en) 1973-11-27
DE2167044A1 (en) 1977-11-10
DE2115718C3 (en) 1979-07-19
DE2115718A1 (en) 1971-10-14
JPS5163197A (en) 1976-06-01
DK149345C (en) 1986-10-13
JPS5227160B2 (en) 1977-07-19
IL36474A0 (en) 1971-05-26
DK149345B (en) 1986-05-12
BE765006A (en) 1971-09-30
NL158497B (en) 1978-11-15
IT8048032A0 (en) 1980-02-28
AT309699B (en) 1973-07-15
SE386179B (en) 1976-08-02
JPS5163198A (en) 1976-06-01
JPS5337360B2 (en) 1978-10-07
CH546777A (en) 1974-03-15
NL7104275A (en) 1971-10-04
GB1351263A (en) 1974-04-24
GB1351262A (en) 1974-04-24
DE2115718B2 (en) 1978-11-02
SU505365A3 (en) 1976-02-28
GB1351261A (en) 1974-04-24
JPS5144960B1 (en) 1976-12-01
DE2167043A1 (en) 1977-10-13
PL83152B1 (en) 1975-12-31
DE2167044C2 (en) 1983-07-14

Similar Documents

Publication Publication Date Title
IL36474A (en) Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes
ZA712045B (en) Process for preparing pentacyclic alkaloids
ZA715124B (en) Process for the preparation of 4-oxocapronitrile
IL37210A (en) Amino-s-triazolylbenzene-sulfonamide derivatives and methods for their production
IL40907A0 (en) Pyrazinoindole derivatives and processes for their preparation
ZA713618B (en) Benzenesulfonyl-urea derivatives and process for their manufacture
PH9228A (en) Process for the preparation of 3-phenyl-5-t-butyl-2-oxadiazolones
ZA715261B (en) Tricyclic compounds and process for the preparation thereof
ZA712180B (en) Aminopropionanilides and process for the preparation thereof
ZA718575B (en) Substituted dioxypiperidines and process for the preparation thereof
IL35257A (en) Microbiological process for preparing 10-hydroxylated pentacyclic alkaloids of the yohimbane family
ZA717875B (en) Synthetic penicillin and process for the preparation thereof
EG10440A (en) Process for the preparation of des-phenylalamin b1-insuli
PH9676A (en) Benzodiazepine derivatives and process of preparing the same
IL35791A (en) Process for the preparation of steroids
HK13576A (en) Novel 1-polyfluoroalkyl-benzodiazepines and methods for their production
IL39545A0 (en) Novel benzimidazoles and process for their preparation
ZA728200B (en) Pyrazinoindole derivatives and processes for their preparation
ZA717892B (en) New 11-alkoxy steroids and process for preparing them
IL37371A0 (en) Novel 6-azido-21-oxygenated steroids and methods for their production
CA948156A (en) Process for the preparation of polychlorcyclopentane and hexachlorcyclopentadiene
IL38029A (en) Process for the preparation of 14-anhydrobufaline
IL36802A0 (en) New carbamyloxyquinoline and process for its preparation
PH12438A (en) Improved process in the preparation of 6-methylene-5-oxytetracycline
PH10379A (en) Thioallophanimidate derivatives and process for the preparation thereof