IL36474A - Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes - Google Patents

Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes

Info

Publication number
IL36474A
IL36474A IL36474A IL3647471A IL36474A IL 36474 A IL36474 A IL 36474A IL 36474 A IL36474 A IL 36474A IL 3647471 A IL3647471 A IL 3647471A IL 36474 A IL36474 A IL 36474A
Authority
IL
Israel
Prior art keywords
homoeburnanes
eburnamonine
vincamine
preparing
novel
Prior art date
Application number
IL36474A
Other languages
English (en)
Other versions
IL36474A0 (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7011406A external-priority patent/FR2081593A1/fr
Priority claimed from FR7032889A external-priority patent/FR2104959A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IL36474A0 publication Critical patent/IL36474A0/xx
Publication of IL36474A publication Critical patent/IL36474A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL36474A 1970-03-31 1971-03-23 Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes IL36474A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7011406A FR2081593A1 (en) 1970-03-31 1970-03-31 Vincamine process
FR7032889A FR2104959A2 (en) 1970-09-10 1970-09-10 Vincamine process

Publications (2)

Publication Number Publication Date
IL36474A0 IL36474A0 (en) 1971-05-26
IL36474A true IL36474A (en) 1975-08-31

Family

ID=26215644

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36474A IL36474A (en) 1970-03-31 1971-03-23 Process for preparing pentacyclic alkaloids of the eburnamonine-vincamine series and novel e-homoeburnanes

Country Status (16)

Country Link
US (1) US3770724A (xx)
JP (3) JPS5144960B1 (xx)
AT (1) AT309699B (xx)
BE (1) BE765006A (xx)
CA (1) CA937570A (xx)
CH (1) CH546777A (xx)
DE (3) DE2115718C3 (xx)
DK (1) DK149345C (xx)
GB (3) GB1351262A (xx)
HU (1) HU163769B (xx)
IL (1) IL36474A (xx)
IT (1) IT8048032A0 (xx)
NL (1) NL158497B (xx)
PL (1) PL83152B1 (xx)
SE (2) SE390414B (xx)
SU (1) SU505365A3 (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL153199B (nl) * 1971-10-25 1977-05-16 Omnium Chimique Sa Werkwijze voor de bereiding van esters van vincaminezuur, alsmede werkwijze voor de bereiding van een geneesmiddel dat een dergelijke ester bevat en gevormd geneesmiddel dat aldus is verkregen.
CH578001A5 (xx) * 1972-04-14 1976-07-30 Sandoz Ag
FR2179620B1 (xx) * 1972-04-14 1975-12-26 Roussel Uclaf
US4033969A (en) * 1972-06-19 1977-07-05 Agence Nationale De Valorisation De La Recherche (Anvar) Vincamine derivatives
FR2259612B1 (xx) * 1974-01-31 1977-09-09 Synthelabo
CH625239A5 (xx) * 1974-08-09 1981-09-15 Buskine Sa
JPS536264U (xx) * 1976-06-30 1978-01-20
HU174502B (hu) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
FR2445328A1 (fr) * 1978-07-12 1980-07-25 Richter Gedeon Vegyeszet Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament
US4428877A (en) 1978-07-12 1984-01-31 Richter Gedeon Vegyeszeti Gyar Rt. Cis-10-bromo-E-homoeburnanes
US4316028A (en) * 1978-11-20 1982-02-16 Sumitomo Chemical Company, Limited Process for producing eburnane derivatives
AU532001B2 (en) * 1978-11-20 1983-09-15 Sumitomo Chemical Company, Limited Polycyclic indole derivatives
HU179292B (en) * 1978-12-01 1982-09-28 Richter Gedeon Vegyeszet Process for preparing ester derivatives of apovincaminic acid
HU180928B (en) * 1979-08-06 1983-05-30 Richter Gedeon Vegyeszet Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives
HU181496B (en) * 1979-08-13 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes
JPS5689589U (xx) * 1979-12-13 1981-07-17
JPS5693693U (xx) * 1979-12-14 1981-07-25
HU185305B (en) * 1981-08-23 1985-01-28 Richter Gedeon Vegyeszet Process for preparing vincine and apovincine
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
JPS59258U (ja) * 1982-06-24 1984-01-05 日本ピラ−工業株式会社 平板形電子管式表示装置
HU187139B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new eburnan derivatives
HU187733B (en) * 1982-06-30 1986-02-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing apovincaminic acid derivatives
HU187140B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new aburnan-oxima ethers
JPS59105767U (ja) * 1983-01-06 1984-07-16 日本ピラ−工業株式会社 平板形電子管式表示装置
JPS6032240A (ja) * 1983-07-30 1985-02-19 Sony Corp 螢光表示装置
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof
CN111205288B (zh) * 2020-02-19 2021-03-30 四川大学 一种(1S,12bS)内酰胺酯化合物的合成方法

Also Published As

Publication number Publication date
AT309699B (de) 1973-07-15
US3770724A (en) 1973-11-06
JPS5144960B1 (xx) 1976-12-01
DE2115718B2 (de) 1978-11-02
NL7104275A (xx) 1971-10-04
JPS5337360B2 (xx) 1978-10-07
DE2115718A1 (de) 1971-10-14
BE765006A (fr) 1971-09-30
JPS5163197A (xx) 1976-06-01
JPS5163198A (xx) 1976-06-01
CH546777A (fr) 1974-03-15
CA937570A (en) 1973-11-27
DE2167043A1 (de) 1977-10-13
DK149345C (da) 1986-10-13
SE386179B (sv) 1976-08-02
DK149345B (da) 1986-05-12
PL83152B1 (en) 1975-12-31
DE2167044A1 (de) 1977-11-10
IL36474A0 (en) 1971-05-26
NL158497B (nl) 1978-11-15
GB1351261A (en) 1974-04-24
JPS5227160B2 (xx) 1977-07-19
IT8048032A0 (it) 1980-02-28
GB1351263A (en) 1974-04-24
DE2115718C3 (de) 1979-07-19
DE2167044C2 (de) 1983-07-14
SE390414B (sv) 1976-12-20
HU163769B (xx) 1973-10-27
GB1351262A (en) 1974-04-24
SU505365A3 (ru) 1976-02-28

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