SE0302811D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0302811D0
SE0302811D0 SE0302811A SE0302811A SE0302811D0 SE 0302811 D0 SE0302811 D0 SE 0302811D0 SE 0302811 A SE0302811 A SE 0302811A SE 0302811 A SE0302811 A SE 0302811A SE 0302811 D0 SE0302811 D0 SE 0302811D0
Authority
SE
Sweden
Prior art keywords
novel compounds
therapy
processes
preparation
general formula
Prior art date
Application number
SE0302811A
Other languages
English (en)
Swedish (sv)
Inventor
Haakan Bladh
Annea Lisius
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29546627&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE0302811(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0302811A priority Critical patent/SE0302811D0/xx
Publication of SE0302811D0 publication Critical patent/SE0302811D0/xx
Priority to UY28572A priority patent/UY28572A1/es
Priority to PCT/SE2004/001522 priority patent/WO2005040167A1/en
Priority to JP2006536485A priority patent/JP2007509141A/ja
Priority to MXPA06004300A priority patent/MXPA06004300A/es
Priority to CNA200480038668XA priority patent/CN1898239A/zh
Priority to US10/575,525 priority patent/US20070249648A1/en
Priority to EP04793824A priority patent/EP1678178A1/en
Priority to KR1020067007682A priority patent/KR20060088557A/ko
Priority to BRPI0415613-7A priority patent/BRPI0415613A/pt
Priority to CA002542226A priority patent/CA2542226A1/en
Priority to AU2004284028A priority patent/AU2004284028B2/en
Priority to TW093132291A priority patent/TW200528451A/zh
Priority to ARP040103863A priority patent/AR046600A1/es
Priority to IL174698A priority patent/IL174698A0/en
Priority to ZA200603174A priority patent/ZA200603174B/xx
Priority to NO20062335A priority patent/NO20062335L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
SE0302811A 2003-10-23 2003-10-23 Novel compounds SE0302811D0 (sv)

Priority Applications (17)

Application Number Priority Date Filing Date Title
SE0302811A SE0302811D0 (sv) 2003-10-23 2003-10-23 Novel compounds
CA002542226A CA2542226A1 (en) 2003-10-23 2004-10-21 Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases
AU2004284028A AU2004284028B2 (en) 2003-10-23 2004-10-21 Novel diazaspiroalkanes and their use for treatment of CCR8 mediated diseases
EP04793824A EP1678178A1 (en) 2003-10-23 2004-10-21 Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases
KR1020067007682A KR20060088557A (ko) 2003-10-23 2004-10-21 신규 디아자스피로알칸 및 ｃｃｒ8 매개 질환의 치료를위한 이의 용도
JP2006536485A JP2007509141A (ja) 2003-10-23 2004-10-21 新規ジアザスピロアルカンおよびｃｃｒ８介在疾患処置のためのその使用
MXPA06004300A MXPA06004300A (es) 2003-10-23 2004-10-21 Nuevos diazaespiroalcanos y su uso para tratamiento de enfermedades mediadas por ccr8.
CNA200480038668XA CN1898239A (zh) 2003-10-23 2004-10-21 新的二氮杂螺烷及其在治疗ccr8介导的疾病中的用途
US10/575,525 US20070249648A1 (en) 2003-10-23 2004-10-21 Novel Diazaspiroalkanes and Their Use for Treatment of Ccr8 Mediated Diseases
UY28572A UY28572A1 (es) 2003-10-23 2004-10-21 Compuestos novedosos
PCT/SE2004/001522 WO2005040167A1 (en) 2003-10-23 2004-10-21 Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases
BRPI0415613-7A BRPI0415613A (pt) 2003-10-23 2004-10-21 novos compostos de diazaspiroalcanos e seu uso no tratamento de doenças mediadas por ccr8
ARP040103863A AR046600A1 (es) 2003-10-23 2004-10-22 Diazaespiroalcanos y su uso como tratamiento para enfermedades mediadas por ccr8
TW093132291A TW200528451A (en) 2003-10-23 2004-10-22 Novel compounds
IL174698A IL174698A0 (en) 2003-10-23 2006-03-30 Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases
ZA200603174A ZA200603174B (en) 2003-10-23 2006-04-20 Novel diazaspiroalkanes and their use for treatment of CCR8 mediated diseases
NO20062335A NO20062335L (no) 2003-10-23 2006-05-23 Nye diazaspiroalkaner og deres anvendelse i behandlingen av CCR8 medierte sykdommer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0302811A SE0302811D0 (sv) 2003-10-23 2003-10-23 Novel compounds

Publications (1)

Publication Number Publication Date
SE0302811D0 true SE0302811D0 (sv) 2003-10-23

Family

ID=29546627

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0302811A SE0302811D0 (sv) 2003-10-23 2003-10-23 Novel compounds

Country Status (17)

Country Link
US (1) US20070249648A1 (enExample)
EP (1) EP1678178A1 (enExample)
JP (1) JP2007509141A (enExample)
KR (1) KR20060088557A (enExample)
CN (1) CN1898239A (enExample)
AR (1) AR046600A1 (enExample)
AU (1) AU2004284028B2 (enExample)
BR (1) BRPI0415613A (enExample)
CA (1) CA2542226A1 (enExample)
IL (1) IL174698A0 (enExample)
MX (1) MXPA06004300A (enExample)
NO (1) NO20062335L (enExample)
SE (1) SE0302811D0 (enExample)
TW (1) TW200528451A (enExample)
UY (1) UY28572A1 (enExample)
WO (1) WO2005040167A1 (enExample)
ZA (1) ZA200603174B (enExample)

Families Citing this family (70)

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SE0202133D0 (sv) 2002-07-08 2002-07-08 Astrazeneca Ab Novel compounds
SE0303090D0 (sv) 2003-11-20 2003-11-20 Astrazeneca Ab Novel compounds
SE0303541D0 (sv) 2003-12-22 2003-12-22 Astrazeneca Ab New compounds
JP4845873B2 (ja) * 2004-03-03 2011-12-28 ケモセントリックス インコーポレーティッド 二環式および架橋した窒素複素環
EP1869044A1 (en) * 2005-04-04 2007-12-26 AstraZeneca AB Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases
JP2008534679A (ja) * 2005-04-04 2008-08-28 アストラゼネカ・アクチエボラーグ 新規ジアザスピロアルカン類およびｃｃｒ８介在疾患の処置のためのそれらの使用
EP1869046A1 (en) * 2005-04-04 2007-12-26 AstraZeneca AB Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases
GB0514018D0 (en) * 2005-07-07 2005-08-17 Ionix Pharmaceuticals Ltd Chemical compounds
TW200800999A (en) * 2005-09-06 2008-01-01 Astrazeneca Ab Novel compounds
US8629147B2 (en) 2005-11-03 2014-01-14 Chembridge Corporation Heterocyclic compounds useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders
US20080247964A1 (en) * 2006-05-08 2008-10-09 Yuelian Xu Substituted azaspiro derivatives
AU2007256597A1 (en) * 2006-06-09 2007-12-13 Icos Corporation Substituted phenyl acetic acids as DP-2 antagonists
KR20090030347A (ko) * 2006-07-19 2009-03-24 아스트라제네카 아베 신규 트리시클릭 스피로피페리딘 화합물, 이들의 합성 및 이들의 케모킨 수용체 활성의 조절제로서의 용도
CN101541795A (zh) * 2006-09-15 2009-09-23 先灵公司 用于治疗疼痛、糖尿病和脂类代谢紊乱的螺-稠合氮杂环丁烷衍生物
WO2008033460A2 (en) * 2006-09-15 2008-03-20 Schering Corporation Treating pain, diabetes, and lipid metabolism disorders
EP2061796A2 (en) 2006-09-15 2009-05-27 Schering Corporation Azetidine and azetidinone derivatives useful in treating pain and disorders of lipid metabolism
WO2008099165A1 (en) * 2007-02-15 2008-08-21 Astrazeneca Ab Piperidine derivatives and their use for treatment of ccr8 mediated diseases
US8278313B2 (en) 2008-03-11 2012-10-02 Abbott Laboratories Macrocyclic spiro pyrimidine derivatives
US8436005B2 (en) 2008-04-03 2013-05-07 Abbott Laboratories Macrocyclic pyrimidine derivatives
WO2009151910A2 (en) * 2008-05-25 2009-12-17 Wyeth Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
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GB201122113D0 (en) * 2011-12-22 2012-02-01 Convergence Pharmaceuticals Novel compounds
AU2013272288B2 (en) * 2012-06-08 2018-01-18 The United States Government As Represented By The Department Of Veterans Affairs FBXO3 inhibitors
PT2861566T (pt) * 2012-06-13 2017-02-08 Hoffmann La Roche Novos diazaspirocicloalcanos e azaspirocicloalcanos
AU2013322838B2 (en) 2012-09-25 2018-02-01 F. Hoffmann-La Roche Ag New bicyclic derivatives
AR095079A1 (es) 2013-03-12 2015-09-16 Hoffmann La Roche Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
US9227978B2 (en) 2013-03-15 2016-01-05 Araxes Pharma Llc Covalent inhibitors of Kras G12C
US10196369B2 (en) * 2013-09-26 2019-02-05 Sanford Burnham Prebys Medical Discovery Institute Spirocyclic EBI2 modulators
JO3805B1 (ar) 2013-10-10 2021-01-31 Araxes Pharma Llc مثبطات كراس جي12سي
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