SE0100764D0 - New assymetric process - Google Patents

New assymetric process

Info

Publication number
SE0100764D0
SE0100764D0 SE0100764A SE0100764A SE0100764D0 SE 0100764 D0 SE0100764 D0 SE 0100764D0 SE 0100764 A SE0100764 A SE 0100764A SE 0100764 A SE0100764 A SE 0100764A SE 0100764 D0 SE0100764 D0 SE 0100764D0
Authority
SE
Sweden
Prior art keywords
assymetric
new
synthesis
chiral
asymmetric
Prior art date
Application number
SE0100764A
Other languages
English (en)
Swedish (sv)
Inventor
William Brown
Niklas Plobeck
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0100764A priority Critical patent/SE0100764D0/xx
Publication of SE0100764D0 publication Critical patent/SE0100764D0/xx
Priority to DE60228548T priority patent/DE60228548D1/de
Priority to PT02701852T priority patent/PT1368325E/pt
Priority to NZ527656A priority patent/NZ527656A/en
Priority to DK02701852T priority patent/DK1368325T3/da
Priority to KR1020037011675A priority patent/KR100856996B1/ko
Priority to PCT/SE2002/000376 priority patent/WO2002070492A1/en
Priority to CNB2005100879382A priority patent/CN1295217C/zh
Priority to JP2002569812A priority patent/JP2004522793A/ja
Priority to ES02701852T priority patent/ES2311050T3/es
Priority to CNB028060326A priority patent/CN1244565C/zh
Priority to AT02701852T priority patent/ATE406354T1/de
Priority to US10/468,989 priority patent/US7045625B2/en
Priority to IL15746002A priority patent/IL157460A0/xx
Priority to BR0207817-1A priority patent/BR0207817A/pt
Priority to CA002440104A priority patent/CA2440104A1/en
Priority to MXPA03007889A priority patent/MXPA03007889A/es
Priority to SI200230739T priority patent/SI1368325T1/sl
Priority to EP02701852A priority patent/EP1368325B1/en
Priority to ZA200306448A priority patent/ZA200306448B/en
Priority to NO20033944A priority patent/NO325156B1/no
Priority to HK04102254.3A priority patent/HK1059436A1/xx
Priority to US11/285,672 priority patent/US7423154B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Quinoline Compounds (AREA)
SE0100764A 2001-03-07 2001-03-07 New assymetric process SE0100764D0 (sv)

Priority Applications (23)

Application Number Priority Date Filing Date Title
SE0100764A SE0100764D0 (sv) 2001-03-07 2001-03-07 New assymetric process
EP02701852A EP1368325B1 (en) 2001-03-07 2002-03-05 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates
CNB028060326A CN1244565C (zh) 2001-03-07 2002-03-05 对于制备二芳基甲基哌嗪衍生物的新不对称方法和新不对称二芳基甲胺中间体
US10/468,989 US7045625B2 (en) 2001-03-07 2002-03-05 Asymmetric process for the preparation of diarylethylpiperazines derivatives and novel asymmetric diarylmethylamines as intermediates
NZ527656A NZ527656A (en) 2001-03-07 2002-03-05 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates
DK02701852T DK1368325T3 (da) 2001-03-07 2002-03-05 Ny asymmetrisk fremgangsmåde til fremstilling af diarylmethylpiperazinderivater og hidtil ukendte asymmetriske diarylmethylaminer som mellemprodukter
KR1020037011675A KR100856996B1 (ko) 2001-03-07 2002-03-05 디아릴메틸피페라진 유도체의 신규한 비대칭 제조 방법 및중간체로서의 신규한 비대칭 디아릴메틸아민
PCT/SE2002/000376 WO2002070492A1 (en) 2001-03-07 2002-03-05 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates
CNB2005100879382A CN1295217C (zh) 2001-03-07 2002-03-05 用于制备二芳基甲基哌嗪衍生物的新不对称二芳基甲胺中间体
JP2002569812A JP2004522793A (ja) 2001-03-07 2002-03-05 ジアリールメチルピペラジン誘導体の新規な不斉製造方法および中間体としての新規なジアリールメチルアミン
ES02701852T ES2311050T3 (es) 2001-03-07 2002-03-05 Nuevo procedimiento asimetrico para la preparacion de derivados de diarilmetilpiperazinas y nuevas diarilmetilaminas asimetricas como intermedios.
DE60228548T DE60228548D1 (de) 2001-03-07 2002-03-05 Neues asymmetrisches verfahren zur herstellung von diarylmethylpiperazinderivaten und neue asymmetrische diarylmethylamine als zwischenprodukte
AT02701852T ATE406354T1 (de) 2001-03-07 2002-03-05 Neues asymmetrisches verfahren zur herstellung von diarylmethylpiperazinderivaten und neue asymmetrische diarylmethylamine als zwischenprodukte
PT02701852T PT1368325E (pt) 2001-03-07 2002-03-05 Novo processo assimétrico para a preparação de derivados de diarilmetilpiperazinas e novas diarilmetilaminas assimétricas como intermediários
IL15746002A IL157460A0 (en) 2001-03-07 2002-03-05 New asymmetric process for the preparation of diarylmethylpiperazine derivatives and novel asymmetric diarylmetylamines as intermediates
BR0207817-1A BR0207817A (pt) 2001-03-07 2002-03-05 Processo para preparar um composto, e, composto
CA002440104A CA2440104A1 (en) 2001-03-07 2002-03-05 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates
MXPA03007889A MXPA03007889A (es) 2001-03-07 2002-03-05 Nuevo proceso asimetrico para preparacion de derivados de diarilmetilpiperazinas y nuevas diarilmetilaminas asimetricas como intermediarios.
SI200230739T SI1368325T1 (sl) 2001-03-07 2002-03-05 Novi asimetrični postopek za pripravo diarilmetilpiperazinskih derivatov in novi asimetrični diarilmetilamini kot intermediati
ZA200306448A ZA200306448B (en) 2001-03-07 2003-08-19 New asymmetric process for the preparation of diaryl-methylpiperazines derivatives and novel asymmetric diarylmethylamines as intermediates.
NO20033944A NO325156B1 (no) 2001-03-07 2003-09-05 Ny asymetrisk fremgangsmate for fremstilling av diarylmetylpiperazinderivater og nye asymetriske diarylmetylaminer som mellomprodukter
HK04102254.3A HK1059436A1 (en) 2001-03-07 2004-03-26 New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates
US11/285,672 US7423154B2 (en) 2001-03-07 2005-11-22 Asymmetric process for the preparation of diarylethylpiperazines derivatives and novel asymmetric diarylmethylamines as intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0100764A SE0100764D0 (sv) 2001-03-07 2001-03-07 New assymetric process

Publications (1)

Publication Number Publication Date
SE0100764D0 true SE0100764D0 (sv) 2001-03-07

Family

ID=20283236

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0100764A SE0100764D0 (sv) 2001-03-07 2001-03-07 New assymetric process

Country Status (21)

Country Link
US (2) US7045625B2 (pt)
EP (1) EP1368325B1 (pt)
JP (1) JP2004522793A (pt)
KR (1) KR100856996B1 (pt)
CN (2) CN1244565C (pt)
AT (1) ATE406354T1 (pt)
BR (1) BR0207817A (pt)
CA (1) CA2440104A1 (pt)
DE (1) DE60228548D1 (pt)
DK (1) DK1368325T3 (pt)
ES (1) ES2311050T3 (pt)
HK (1) HK1059436A1 (pt)
IL (1) IL157460A0 (pt)
MX (1) MXPA03007889A (pt)
NO (1) NO325156B1 (pt)
NZ (1) NZ527656A (pt)
PT (1) PT1368325E (pt)
SE (1) SE0100764D0 (pt)
SI (1) SI1368325T1 (pt)
WO (1) WO2002070492A1 (pt)
ZA (1) ZA200306448B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114560781A (zh) * 2022-03-01 2022-05-31 无锡捷化医药科技有限公司 一种n,n-二(2-氯乙基)-4-硝基苯基丙氨酸甲酯的制备方法
CN114702457A (zh) * 2022-03-30 2022-07-05 青岛科技大学 一种二芳基甲胺类化合物的绿色合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
DK0711289T3 (da) * 1993-07-30 2000-11-06 Delta Pharmaceuticals Inc Piperazinforbindelser til anvendelse i terapi
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) * 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

Also Published As

Publication number Publication date
CN1721407A (zh) 2006-01-18
HK1059436A1 (en) 2004-07-02
JP2004522793A (ja) 2004-07-29
NO325156B1 (no) 2008-02-11
PT1368325E (pt) 2008-10-27
NO20033944D0 (no) 2003-09-05
US7423154B2 (en) 2008-09-09
DK1368325T3 (da) 2008-11-24
CN1494532A (zh) 2004-05-05
NO20033944L (no) 2003-10-31
US7045625B2 (en) 2006-05-16
KR20030080075A (ko) 2003-10-10
ZA200306448B (en) 2004-09-08
DE60228548D1 (de) 2008-10-09
CA2440104A1 (en) 2002-09-12
NZ527656A (en) 2005-04-29
MXPA03007889A (es) 2003-12-04
CN1295217C (zh) 2007-01-17
IL157460A0 (en) 2004-03-28
ES2311050T3 (es) 2009-02-01
ATE406354T1 (de) 2008-09-15
EP1368325B1 (en) 2008-08-27
EP1368325A1 (en) 2003-12-10
SI1368325T1 (sl) 2008-12-31
WO2002070492A1 (en) 2002-09-12
BR0207817A (pt) 2004-03-09
US20060074238A1 (en) 2006-04-06
KR100856996B1 (ko) 2008-09-04
US20040077861A1 (en) 2004-04-22
CN1244565C (zh) 2006-03-08

Similar Documents

Publication Publication Date Title
EA200701738A1 (ru) Способ получения транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина
DE602004019187D1 (de) Verfahren zur herstellung verbesserter angedickter getränke gegen dysphagie
EA200400491A1 (ru) Полиморфная форма римонабанта, способ её получения и содержащие её фармацевтические композиции
ATE486850T1 (de) Synthese von enantiomerenreinen, aminosubstituierten kondensierten bicyclischen ringen
HUP0000777A2 (hu) Ritalinsav só rezolválása
DE60001657D1 (de) Verfahren zur herstellung von n-(4-cyan-3-trifluormethylphenyl)-3-(4-flurophenylsulfonyl)-2-hydroxy-2-methylpropionamid
BRPI0407282A (pt) Processo para preparação de inibidores de pirrolotriazina cinase
EA200600485A1 (ru) Способ получения производных 2-оксо-1-пирролидина
DE60228724D1 (de) Verfahren zur herstellung von beraprost und dessen salzen
SE0100764D0 (sv) New assymetric process
DE60324607D1 (de) Pyrrolo(2,1-c)(1,4)benzodiazepin-dimere als antitumormittel und verfahren dafür
HK1099759A1 (en) A process for the resolution of nefopam
EA200600656A1 (ru) Способ получения (s)- или (r)-4-галоген-3-гидроксибутиратов
HUP9701364A2 (hu) Eljárás {1-metil-2-[3-(trifluor-metil)-fenil]-etil}-amin (R)- és (S)-izomereinek előállítására, és az izomerek és sóik
ATE280769T1 (de) Verfahren zur herstellung von vitronectin- rezeptorantagonisten
ATE370950T1 (de) Verfahren zur herstellung von (1s,4r)-cis-4-(2- amino-6-chlor-9h-purin-9-yl)-2-cyclopenten-1- methanol
ECSP034515A (es) Proceso para producir compuestos quirales
ATE399757T1 (de) Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol
ATE318815T1 (de) Verfahren zur herstellung von enantiomeren von indol-2,3-dion-3-oximderivaten
UA91153C2 (ru) Способ получения формы и венлафаксина гидрохлорида
DE50312447D1 (de) Verfahren zur herstellung von 4,6-dichlor-5-fluorpyrimidin
ATE399876T1 (de) Chemoenzymatisches verfahren zur stereoselektiven herstellung von optisch-angereicherten phenylglycidate
DE602004027401D1 (de) Verfahren zur herstellung von polymorphen von sertralin hydrochlorid
ATE440098T1 (de) Enantiomerenreine hexahydropyrrolocyclopentapyridin-derivate
IT1317886B1 (it) Procedimento per la preparazione di 9,10-diidro-pirrolo (2,1-b)(1,3)benzotiazepine 9-ammino sostituite.