DK1368325T3 - Ny asymmetrisk fremgangsmåde til fremstilling af diarylmethylpiperazinderivater og hidtil ukendte asymmetriske diarylmethylaminer som mellemprodukter - Google Patents
Ny asymmetrisk fremgangsmåde til fremstilling af diarylmethylpiperazinderivater og hidtil ukendte asymmetriske diarylmethylaminer som mellemprodukterInfo
- Publication number
- DK1368325T3 DK1368325T3 DK02701852T DK02701852T DK1368325T3 DK 1368325 T3 DK1368325 T3 DK 1368325T3 DK 02701852 T DK02701852 T DK 02701852T DK 02701852 T DK02701852 T DK 02701852T DK 1368325 T3 DK1368325 T3 DK 1368325T3
- Authority
- DK
- Denmark
- Prior art keywords
- asymmetric
- preparation
- diarylmethylamines
- diarylmethylpiperazine
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Furan Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0100764A SE0100764D0 (sv) | 2001-03-07 | 2001-03-07 | New assymetric process |
| PCT/SE2002/000376 WO2002070492A1 (en) | 2001-03-07 | 2002-03-05 | New asymmetric process for the preparation of diarylmethylpiperazines derivatives and novel asymmetric diarylmetylamines as intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1368325T3 true DK1368325T3 (da) | 2008-11-24 |
Family
ID=20283236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02701852T DK1368325T3 (da) | 2001-03-07 | 2002-03-05 | Ny asymmetrisk fremgangsmåde til fremstilling af diarylmethylpiperazinderivater og hidtil ukendte asymmetriske diarylmethylaminer som mellemprodukter |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7045625B2 (pt) |
| EP (1) | EP1368325B1 (pt) |
| JP (1) | JP2004522793A (pt) |
| KR (1) | KR100856996B1 (pt) |
| CN (2) | CN1244565C (pt) |
| AT (1) | ATE406354T1 (pt) |
| BR (1) | BR0207817A (pt) |
| CA (1) | CA2440104A1 (pt) |
| DE (1) | DE60228548D1 (pt) |
| DK (1) | DK1368325T3 (pt) |
| ES (1) | ES2311050T3 (pt) |
| HK (1) | HK1059436A1 (pt) |
| IL (1) | IL157460A0 (pt) |
| MX (1) | MXPA03007889A (pt) |
| NO (1) | NO325156B1 (pt) |
| NZ (1) | NZ527656A (pt) |
| PT (1) | PT1368325E (pt) |
| SE (1) | SE0100764D0 (pt) |
| SI (1) | SI1368325T1 (pt) |
| WO (1) | WO2002070492A1 (pt) |
| ZA (1) | ZA200306448B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114560781A (zh) * | 2022-03-01 | 2022-05-31 | 无锡捷化医药科技有限公司 | 一种n,n-二(2-氯乙基)-4-硝基苯基丙氨酸甲酯的制备方法 |
| CN114702457A (zh) * | 2022-03-30 | 2022-07-05 | 青岛科技大学 | 一种二芳基甲胺类化合物的绿色合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9202238D0 (en) * | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| DK0711289T3 (da) * | 1993-07-30 | 2000-11-06 | Delta Pharmaceuticals Inc | Piperazinforbindelser til anvendelse i terapi |
| SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| SE9904673D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE0001209D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-03-07 SE SE0100764A patent/SE0100764D0/xx unknown
-
2002
- 2002-03-05 EP EP02701852A patent/EP1368325B1/en not_active Expired - Lifetime
- 2002-03-05 PT PT02701852T patent/PT1368325E/pt unknown
- 2002-03-05 SI SI200230739T patent/SI1368325T1/sl unknown
- 2002-03-05 MX MXPA03007889A patent/MXPA03007889A/es active IP Right Grant
- 2002-03-05 KR KR1020037011675A patent/KR100856996B1/ko not_active IP Right Cessation
- 2002-03-05 BR BR0207817-1A patent/BR0207817A/pt not_active IP Right Cessation
- 2002-03-05 DK DK02701852T patent/DK1368325T3/da active
- 2002-03-05 CN CNB028060326A patent/CN1244565C/zh not_active Expired - Fee Related
- 2002-03-05 JP JP2002569812A patent/JP2004522793A/ja active Pending
- 2002-03-05 WO PCT/SE2002/000376 patent/WO2002070492A1/en active IP Right Grant
- 2002-03-05 CN CNB2005100879382A patent/CN1295217C/zh not_active Expired - Fee Related
- 2002-03-05 IL IL15746002A patent/IL157460A0/xx unknown
- 2002-03-05 DE DE60228548T patent/DE60228548D1/de not_active Expired - Fee Related
- 2002-03-05 CA CA002440104A patent/CA2440104A1/en not_active Abandoned
- 2002-03-05 AT AT02701852T patent/ATE406354T1/de not_active IP Right Cessation
- 2002-03-05 US US10/468,989 patent/US7045625B2/en not_active Expired - Fee Related
- 2002-03-05 NZ NZ527656A patent/NZ527656A/en unknown
- 2002-03-05 ES ES02701852T patent/ES2311050T3/es not_active Expired - Lifetime
-
2003
- 2003-08-19 ZA ZA200306448A patent/ZA200306448B/en unknown
- 2003-09-05 NO NO20033944A patent/NO325156B1/no not_active IP Right Cessation
-
2004
- 2004-03-26 HK HK04102254.3A patent/HK1059436A1/xx not_active IP Right Cessation
-
2005
- 2005-11-22 US US11/285,672 patent/US7423154B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SE0100764D0 (sv) | 2001-03-07 |
| CN1721407A (zh) | 2006-01-18 |
| HK1059436A1 (en) | 2004-07-02 |
| JP2004522793A (ja) | 2004-07-29 |
| NO325156B1 (no) | 2008-02-11 |
| PT1368325E (pt) | 2008-10-27 |
| NO20033944D0 (no) | 2003-09-05 |
| US7423154B2 (en) | 2008-09-09 |
| CN1494532A (zh) | 2004-05-05 |
| NO20033944L (no) | 2003-10-31 |
| US7045625B2 (en) | 2006-05-16 |
| KR20030080075A (ko) | 2003-10-10 |
| ZA200306448B (en) | 2004-09-08 |
| DE60228548D1 (de) | 2008-10-09 |
| CA2440104A1 (en) | 2002-09-12 |
| NZ527656A (en) | 2005-04-29 |
| MXPA03007889A (es) | 2003-12-04 |
| CN1295217C (zh) | 2007-01-17 |
| IL157460A0 (en) | 2004-03-28 |
| ES2311050T3 (es) | 2009-02-01 |
| ATE406354T1 (de) | 2008-09-15 |
| EP1368325B1 (en) | 2008-08-27 |
| EP1368325A1 (en) | 2003-12-10 |
| SI1368325T1 (sl) | 2008-12-31 |
| WO2002070492A1 (en) | 2002-09-12 |
| BR0207817A (pt) | 2004-03-09 |
| US20060074238A1 (en) | 2006-04-06 |
| KR100856996B1 (ko) | 2008-09-04 |
| US20040077861A1 (en) | 2004-04-22 |
| CN1244565C (zh) | 2006-03-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200400491A1 (ru) | Полиморфная форма римонабанта, способ её получения и содержащие её фармацевтические композиции | |
| DK1940789T3 (da) | Fremgangsmåder og forbindelser til fremstilling af CC-1065-analoger | |
| CO5550472A2 (es) | Piperazinas heterociclicas sustituidas para el tratamiento de la esquizofrenia | |
| ATE486850T1 (de) | Synthese von enantiomerenreinen, aminosubstituierten kondensierten bicyclischen ringen | |
| UA106191C2 (ru) | Способ получения транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина | |
| ATE234294T1 (de) | Verfahren zur herstellung von n-(4-cyan-3- trifluormethylphenyl)-3-(4-flurophenylsulfonyl) 2-hydroxy-2-methylpropionamid | |
| HUP0000777A2 (hu) | Ritalinsav só rezolválása | |
| AR072336A1 (es) | Derivados de la 3-carboxipropil-aminotetralina, composiciones farmaceuticas que los contienen, procedimiento para su preparacion, intermediarios y su procedimiento de preparacion | |
| DE60228724D1 (de) | Verfahren zur herstellung von beraprost und dessen salzen | |
| IL195385A0 (en) | A process for preparing arylamine derivatives | |
| DK1368325T3 (da) | Ny asymmetrisk fremgangsmåde til fremstilling af diarylmethylpiperazinderivater og hidtil ukendte asymmetriske diarylmethylaminer som mellemprodukter | |
| DE60324607D1 (de) | Pyrrolo(2,1-c)(1,4)benzodiazepin-dimere als antitumormittel und verfahren dafür | |
| AR056805A1 (es) | Un proceso para oxidacion para la preparcion de n- (3- amino-1- ( ciclobutilmetil) -2,3- dioxopropil ) -3-(n-(( ter-butilamino) carbonil )-3- metil- l- valil) -6,6- dimetil-3- azabiciclo (3.1.0) hexano -2- carboxamida y compuestos ralacionados | |
| AR038931A1 (es) | Proceso para la preparacion de piperazinas quirales 1,4-disustituidas | |
| AR044670A1 (es) | Procedimiento para la sintesis del acido (2s, 3as, 7as) - perhidroindol - 2 carboxilico y aplicacion en la sintesis de perindopril | |
| ECSP034515A (es) | Proceso para producir compuestos quirales | |
| DE602004006021D1 (de) | Verfahren zur racematspaltung von nefopam | |
| DK1532146T3 (da) | Fremgangsmåde til fremstilling af enantiomerer af indol-2,3-dion-3-oximderivater | |
| DE602004014822D1 (de) | Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol | |
| DE602004008486D1 (de) | Verfahren zur herstellung von (1s,4r)-cis-4-ä2-amino-6-chlor-9h-purin-9-ylü-2-cyclopenten-1-methanol | |
| BRPI0409511A (pt) | composto, composição farmacêutica, e, uso do composto | |
| AR062481A1 (es) | Proceso para preparar derivados de indolinona fenilaminopropanol | |
| AR056543A1 (es) | Metodo de preparacion de (3-cloro-4-fluorofenil)-(4-fluoro-4[[(5-metil-pirimidin-2-ilmetil)-amino]-metil]-piperidin-1-il)-metanona y compuestos intermediarios derivados de pirimidina | |
| DK1692084T3 (da) | Fremgangsmåde til fremstilling af enantiomert berigende aminosyrer | |
| BRPI0410125A (pt) | intermediários úteis para a sìntese de inibidores de protease de hiv, e métodos para os preparar |