SA517381471B1 - وحدة عقار- جهاز تحتوي على كيناجولايد - Google Patents

وحدة عقار- جهاز تحتوي على كيناجولايد

Info

Publication number
SA517381471B1
SA517381471B1 SA517381471A SA517381471A SA517381471B1 SA 517381471 B1 SA517381471 B1 SA 517381471B1 SA 517381471 A SA517381471 A SA 517381471A SA 517381471 A SA517381471 A SA 517381471A SA 517381471 B1 SA517381471 B1 SA 517381471B1
Authority
SA
Saudi Arabia
Prior art keywords
drug
device unit
poly
quinagolide
alkylene oxide
Prior art date
Application number
SA517381471A
Other languages
English (en)
Inventor
نيكلاس بتري أكسيل
روس اليستاير
مكدونالد بول
هاليداي جانيت
كارليس أرس سايز جوان
راباني جوهير
كار دينيس
كوتشراني روبرت
ينج كلايري
قدير محمد
Original Assignee
فيرينج بي في
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51951583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SA517381471(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by فيرينج بي في filed Critical فيرينج بي في
Publication of SA517381471B1 publication Critical patent/SA517381471B1/ar

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/001—Combinations of extrusion moulding with other shaping operations
    • B29C48/0021—Combinations of extrusion moulding with other shaping operations combined with joining, lining or laminating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2033/00—Use of polymers of unsaturated acids or derivatives thereof as moulding material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
    • B29K2105/0035—Medical or pharmaceutical agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/754—Pessaries

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)

Abstract

يتعلق الاختراع الحالي بتحديد مجموعة من البوليمرات المشتركة الكتلية block copolymers للبولي يوريثان polyurethane والمعدة خصيصًا للاستخدام في وحدات جهاز العقار البوليمري الصيدلاني pharmaceutical polymeric drug-device units والتي تقدم تحكمًا أفضل في إطلاق العقار. وعلى وجه التحديد، يتم توفير وحدة عقار-جهاز بوليمري polymeric drug-device unit تشتمل على مجموعة من البوليمرات المشتركة الكتلية block copolymer للبولي يوريثان polyurethane التي يتم الحصول عليها من التفاعل مع بولي (ألكيلين أكسيد) poly(alkylene oxide)؛ مركب ثنائي الوظيفة؛ أيزو سيانات ثنائي الوظيفة difunctional isocyanate ؛ واختيارياً مجموعات من بوليمر كتلي مشترك يشتمل على بولي (ألكيلين أكسيد) poly(alkylene oxide) blocks ؛ وكيناجولايد quinagolide كعامل نشط صيدلانياً. يمكن استخدام وحدات العقار- الجهاز في علاج و/ أو الوقاية من الانتباذ البطاني الرحمي prevention of endometriosis. شكل 1.
SA517381471A 2014-11-07 2017-05-06 وحدة عقار- جهاز تحتوي على كيناجولايد SA517381471B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14192372.2A EP3017809A1 (en) 2014-11-07 2014-11-07 Drug-device unit containing quinagolide
PCT/EP2015/075849 WO2016071466A1 (en) 2014-11-07 2015-11-05 Drug-device unit containing quinagolide

Publications (1)

Publication Number Publication Date
SA517381471B1 true SA517381471B1 (ar) 2022-03-06

Family

ID=51951583

Family Applications (1)

Application Number Title Priority Date Filing Date
SA517381471A SA517381471B1 (ar) 2014-11-07 2017-05-06 وحدة عقار- جهاز تحتوي على كيناجولايد

Country Status (33)

Country Link
US (2) US20180008535A1 (ar)
EP (3) EP3017809A1 (ar)
JP (2) JP6907120B2 (ar)
KR (1) KR102612852B1 (ar)
CN (2) CN116212032A (ar)
AR (1) AR102571A1 (ar)
AU (2) AU2015341734C1 (ar)
CA (1) CA2966473A1 (ar)
CL (1) CL2017001119A1 (ar)
CO (1) CO2017005578A2 (ar)
DK (1) DK3215118T3 (ar)
EA (2) EA201991882A2 (ar)
ES (1) ES2877973T3 (ar)
HR (1) HRP20210961T1 (ar)
HU (1) HUE054951T2 (ar)
IL (1) IL252088B (ar)
JO (1) JO3561B1 (ar)
LT (1) LT3215118T (ar)
MA (2) MA56414A (ar)
MD (1) MD3215118T2 (ar)
MX (1) MX2017005828A (ar)
MY (1) MY193638A (ar)
PH (1) PH12017550005A1 (ar)
PL (1) PL3215118T3 (ar)
PT (1) PT3215118T (ar)
RS (1) RS62018B1 (ar)
SA (1) SA517381471B1 (ar)
SG (1) SG11201703596SA (ar)
SI (1) SI3215118T1 (ar)
TN (1) TN2017000175A1 (ar)
TW (1) TWI685339B (ar)
UA (1) UA122329C2 (ar)
WO (1) WO2016071466A1 (ar)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020091456A1 (ko) 2018-10-31 2020-05-07 ㈜아모레퍼시픽 바이오 폴리머를 포함하는 코어-쉘 네트워크 구조체 및 이를 포함하는 조성물
KR20210069344A (ko) 2019-12-03 2021-06-11 (주)아모레퍼시픽 바이오 폴리머를 포함하는 효능물질 전달체
WO2023031218A1 (en) 2021-08-31 2023-03-09 Ferring B.V. Diagnosis and treatment of ectopic endometriosis

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235988A (en) 1976-12-13 1980-11-25 Imperial Chemical Industries Limited Delivery means for biologically active agents
AU2004233997C1 (en) 2003-04-29 2014-01-30 Massachusetts Institiute Of Technology Methods and devices for the sustained release of multiple drugs
US20070043332A1 (en) 2003-07-10 2007-02-22 Galen (Chemiclas) Liimited Intravaginal drug delivery devices
WO2005025549A2 (en) * 2003-09-10 2005-03-24 Noven Pharmaceuticals, Inc. Multi-layer transdermal drug delivery device
ATE475420T1 (de) 2005-04-29 2010-08-15 Ferring Int Ct Sa Behandlung oder vorbeugung des ovariellen überstimulationssyndroms (ohss) mit einem dopaminagonisten
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
SA08290041B1 (ar) 2007-02-01 2012-06-05 فيرينج انترناشونال سنتر اس آيه أدوية من أجل معالجة بطانة الرحم
US20110045076A1 (en) 2008-01-25 2011-02-24 Kiser Patrick F Linear order release polymer
US8383152B2 (en) * 2008-01-25 2013-02-26 Gruenenthal Gmbh Pharmaceutical dosage form
US20100040671A1 (en) 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US20100210600A1 (en) * 2009-02-19 2010-08-19 Prelief Inc. Methods and Compositions for Treating Urogenital Disorders
CA2765997A1 (en) 2009-06-26 2010-12-29 Ferring B.V. Treatment of endometriosis
JP2013525285A (ja) * 2010-04-08 2013-06-20 サンフォード−バーナム メディカル リサーチ インスティテュート 化合物の送達を増強するための方法および組成物
ES2728975T3 (es) 2010-11-15 2019-10-29 Dsm Ip Assets Bv Dispositivo intravaginal de aporte de fármacos que comprende un copolímero de poliuretano
KR20140074281A (ko) 2011-07-20 2014-06-17 패트릭 에프. 카이저 약물 전달용 질내 장치
US10137199B2 (en) * 2013-05-14 2018-11-27 Biotime, Inc. Thiolated hyaluronan-based hydrogels cross-linked using oxidized glutathione
US10413504B2 (en) * 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system

Also Published As

Publication number Publication date
EP3215118A1 (en) 2017-09-13
EA033806B1 (ru) 2019-11-27
TN2017000175A1 (en) 2018-10-19
EP3215118B1 (en) 2021-03-17
JP6907120B2 (ja) 2021-07-21
IL252088A0 (en) 2017-07-31
JP2017533272A (ja) 2017-11-09
CN106999422A (zh) 2017-08-01
EA201991882A2 (ru) 2020-01-31
TWI685339B (zh) 2020-02-21
EP3017809A1 (en) 2016-05-11
MX2017005828A (es) 2017-11-13
WO2016071466A1 (en) 2016-05-12
JO3561B1 (ar) 2020-07-05
AU2020270480A1 (en) 2020-12-17
SG11201703596SA (en) 2017-06-29
HUE054951T2 (hu) 2021-10-28
CO2017005578A2 (es) 2017-08-31
IL252088B (en) 2022-04-01
MA56414A (fr) 2022-05-04
BR112017009476A2 (pt) 2018-01-02
CL2017001119A1 (es) 2018-01-05
MY193638A (en) 2022-10-21
EA201790898A8 (ru) 2018-01-31
PT3215118T (pt) 2021-05-31
ES2877973T3 (es) 2021-11-17
AU2015341734A1 (en) 2017-06-01
KR102612852B1 (ko) 2023-12-11
MA40897B1 (fr) 2021-04-30
LT3215118T (lt) 2021-06-10
SI3215118T1 (sl) 2021-08-31
US20220040094A1 (en) 2022-02-10
PH12017550005A1 (en) 2017-10-18
UA122329C2 (uk) 2020-10-26
EP3892261A1 (en) 2021-10-13
MD3215118T2 (ro) 2021-08-31
AU2015341734B2 (en) 2020-08-20
CN116212032A (zh) 2023-06-06
DK3215118T3 (da) 2021-06-21
HRP20210961T1 (hr) 2021-09-17
MA40897A (fr) 2017-09-13
TW201625245A (zh) 2016-07-16
US20180008535A1 (en) 2018-01-11
PL3215118T3 (pl) 2021-07-26
EA033806B9 (ru) 2019-12-19
AR102571A1 (es) 2017-03-08
KR20170080671A (ko) 2017-07-10
RS62018B1 (sr) 2021-07-30
AU2015341734C1 (en) 2020-12-17
JP2021155444A (ja) 2021-10-07
EA201790898A1 (ru) 2017-11-30
CA2966473A1 (en) 2016-05-12

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