UA122329C2 - Комплекс лікарський засіб-пристрій з вмістом хінаголіду - Google Patents

Комплекс лікарський засіб-пристрій з вмістом хінаголіду

Info

Publication number
UA122329C2
UA122329C2 UAA201705500A UAA201705500A UA122329C2 UA 122329 C2 UA122329 C2 UA 122329C2 UA A201705500 A UAA201705500 A UA A201705500A UA A201705500 A UAA201705500 A UA A201705500A UA 122329 C2 UA122329 C2 UA 122329C2
Authority
UA
Ukraine
Prior art keywords
drug
device unit
poly
quinagolide
alkylene oxide
Prior art date
Application number
UAA201705500A
Other languages
English (en)
Inventor
Дженет Холлідей
Дженет Холлидэй
Деніс Карр
Денис Карр
Алістер Росс
Алистер Росс
Клер Янг
Пол МакДональд
Мохаммад Кадир
Роберт Кокрейн
Гоухер Рабані
Гоухер Рабани
Саес Хоан Карлес Арсе
Аксель Ніклас Петри
Аксель Никлас ПЕТРИ
Original Assignee
Феррінг Б.В.
Ферринг Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51951583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA122329(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Феррінг Б.В., Ферринг Б.В. filed Critical Феррінг Б.В.
Publication of UA122329C2 publication Critical patent/UA122329C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/001—Combinations of extrusion moulding with other shaping operations
    • B29C48/0021—Combinations of extrusion moulding with other shaping operations combined with joining, lining or laminating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2033/00—Use of polymers of unsaturated acids or derivatives thereof as moulding material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
    • B29K2105/0035—Medical or pharmaceutical agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/754—Pessaries

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Даний винахід ґрунтується на виявленні групи поліуретанових блок-співполімерів, які особливо підходять для застосування в полімерних засобах доставки лікарських препаратів і які здійснюють кращий контроль вивільнення лікарських препаратів. Зокрема, пропонується засіб доставки лікарського препарату, що включає в себе поліуретановий блок-співполімер, який отримують шляхом спільної реакції полі(алкіленоксиду); біфункціональної сполуки; біфункціонального ізоціанату; і необов'язково блок-співполімеру з вмістом блоків полі(алкіленоксиду); і хінаголіду як фармацевтично активного агента. Засіб доставки лікарського засобу може знайти застосування у лікуванні і/або профілактиці ендометріозу.
UAA201705500A 2014-11-07 2015-11-05 Комплекс лікарський засіб-пристрій з вмістом хінаголіду UA122329C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14192372.2A EP3017809A1 (en) 2014-11-07 2014-11-07 Drug-device unit containing quinagolide
PCT/EP2015/075849 WO2016071466A1 (en) 2014-11-07 2015-11-05 Drug-device unit containing quinagolide

Publications (1)

Publication Number Publication Date
UA122329C2 true UA122329C2 (uk) 2020-10-26

Family

ID=51951583

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201705500A UA122329C2 (uk) 2014-11-07 2015-11-05 Комплекс лікарський засіб-пристрій з вмістом хінаголіду

Country Status (34)

Country Link
US (2) US20180008535A1 (uk)
EP (3) EP3017809A1 (uk)
JP (2) JP6907120B2 (uk)
KR (1) KR102612852B1 (uk)
CN (2) CN116212032A (uk)
AR (1) AR102571A1 (uk)
AU (2) AU2015341734C1 (uk)
CA (1) CA2966473A1 (uk)
CL (1) CL2017001119A1 (uk)
CO (1) CO2017005578A2 (uk)
DK (1) DK3215118T3 (uk)
EA (2) EA201991882A2 (uk)
ES (1) ES2877973T3 (uk)
HR (1) HRP20210961T1 (uk)
HU (1) HUE054951T2 (uk)
IL (1) IL252088B (uk)
JO (1) JO3561B1 (uk)
LT (1) LT3215118T (uk)
MA (2) MA40897B1 (uk)
MD (1) MD3215118T2 (uk)
MX (1) MX2017005828A (uk)
MY (1) MY193638A (uk)
NZ (1) NZ731763A (uk)
PH (1) PH12017550005A1 (uk)
PL (1) PL3215118T3 (uk)
PT (1) PT3215118T (uk)
RS (1) RS62018B1 (uk)
SA (1) SA517381471B1 (uk)
SG (1) SG11201703596SA (uk)
SI (1) SI3215118T1 (uk)
TN (1) TN2017000175A1 (uk)
TW (1) TWI685339B (uk)
UA (1) UA122329C2 (uk)
WO (1) WO2016071466A1 (uk)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11896685B2 (en) 2018-10-31 2024-02-13 Amorepacific Corporation Core-shell network structure comprising biopolymer and composition comprising same
KR20210069344A (ko) 2019-12-03 2021-06-11 (주)아모레퍼시픽 바이오 폴리머를 포함하는 효능물질 전달체
EP4395751A1 (en) 2021-08-31 2024-07-10 Ferring B.V. Diagnosis and treatment of ectopic endometriosis
WO2024153752A1 (en) 2023-01-20 2024-07-25 Ferring B.V. Stereoselective synthesis of intermediates and synthesis of quinagolids

Family Cites Families (17)

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US4235988A (en) 1976-12-13 1980-11-25 Imperial Chemical Industries Limited Delivery means for biologically active agents
EP1620060B1 (en) 2003-04-29 2010-03-24 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
US20070043332A1 (en) 2003-07-10 2007-02-22 Galen (Chemiclas) Liimited Intravaginal drug delivery devices
WO2005025549A2 (en) * 2003-09-10 2005-03-24 Noven Pharmaceuticals, Inc. Multi-layer transdermal drug delivery device
CA2605972C (en) 2005-04-29 2011-08-02 Ferring International Center S.A. Treatment or prevention of ovarian hyperstimulation syndrome (ohss) using a dopamine agonist
GB0613638D0 (en) * 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
SA08290041B1 (ar) 2007-02-01 2012-06-05 فيرينج انترناشونال سنتر اس آيه أدوية من أجل معالجة بطانة الرحم
BRPI0906467C1 (pt) * 2008-01-25 2021-05-25 Gruenenthal Gmbh forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada
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US20100040671A1 (en) 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
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JP2013525285A (ja) * 2010-04-08 2013-06-20 サンフォード−バーナム メディカル リサーチ インスティテュート 化合物の送達を増強するための方法および組成物
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BR112014001450A2 (pt) * 2011-07-20 2017-07-18 F Kiser Patrick dispositivos intravaginais para distribuição de droga
US10137199B2 (en) * 2013-05-14 2018-11-27 Biotime, Inc. Thiolated hyaluronan-based hydrogels cross-linked using oxidized glutathione
US10413504B2 (en) * 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system

Also Published As

Publication number Publication date
AU2015341734C1 (en) 2020-12-17
SA517381471B1 (ar) 2022-03-06
EA201991882A2 (ru) 2020-01-31
EP3215118B1 (en) 2021-03-17
CN116212032A (zh) 2023-06-06
PL3215118T3 (pl) 2021-07-26
MA40897B1 (fr) 2021-04-30
HUE054951T2 (hu) 2021-10-28
RS62018B1 (sr) 2021-07-30
IL252088A0 (en) 2017-07-31
US20180008535A1 (en) 2018-01-11
MY193638A (en) 2022-10-21
MD3215118T2 (ro) 2021-08-31
US20220040094A1 (en) 2022-02-10
WO2016071466A1 (en) 2016-05-12
NZ731763A (en) 2024-04-26
EP3017809A1 (en) 2016-05-11
DK3215118T3 (da) 2021-06-21
EP3215118A1 (en) 2017-09-13
BR112017009476A2 (pt) 2018-01-02
LT3215118T (lt) 2021-06-10
EA033806B9 (ru) 2019-12-19
JP2021155444A (ja) 2021-10-07
JP6907120B2 (ja) 2021-07-21
PT3215118T (pt) 2021-05-31
AU2020270480A1 (en) 2020-12-17
MX2017005828A (es) 2017-11-13
SG11201703596SA (en) 2017-06-29
EA201790898A1 (ru) 2017-11-30
EA201790898A8 (ru) 2018-01-31
MA40897A (fr) 2017-09-13
TW201625245A (zh) 2016-07-16
CN106999422A (zh) 2017-08-01
CO2017005578A2 (es) 2017-08-31
IL252088B (en) 2022-04-01
PH12017550005A1 (en) 2017-10-18
TWI685339B (zh) 2020-02-21
EP3892261A1 (en) 2021-10-13
CL2017001119A1 (es) 2018-01-05
JO3561B1 (ar) 2020-07-05
SI3215118T1 (sl) 2021-08-31
KR102612852B1 (ko) 2023-12-11
ES2877973T3 (es) 2021-11-17
AR102571A1 (es) 2017-03-08
EA033806B1 (ru) 2019-11-27
TN2017000175A1 (en) 2018-10-19
HRP20210961T1 (hr) 2021-09-17
AU2015341734A1 (en) 2017-06-01
JP2017533272A (ja) 2017-11-09
AU2015341734B2 (en) 2020-08-20
CA2966473A1 (en) 2016-05-12
KR20170080671A (ko) 2017-07-10
MA56414A (fr) 2022-05-04

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