MD3215118T2 - Unitate de dispozitiv medical conţinând quinagolidă - Google Patents
Unitate de dispozitiv medical conţinând quinagolidăInfo
- Publication number
- MD3215118T2 MD3215118T2 MDE20170069T MDE20170069T MD3215118T2 MD 3215118 T2 MD3215118 T2 MD 3215118T2 MD E20170069 T MDE20170069 T MD E20170069T MD E20170069 T MDE20170069 T MD E20170069T MD 3215118 T2 MD3215118 T2 MD 3215118T2
- Authority
- MD
- Moldova
- Prior art keywords
- drug
- device unit
- quinagolide
- poly
- unit containing
- Prior art date
Links
- GDFGTRDCCWFXTG-SCTDSRPQSA-N (3r,4ar,10as)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2h-benzo[g]quinoline Chemical compound C1=CC=C2C[C@@H]3N(CCC)C[C@H](NS(=O)(=O)N(CC)CC)C[C@H]3CC2=C1O GDFGTRDCCWFXTG-SCTDSRPQSA-N 0.000 title abstract 2
- 229960000924 quinagolide Drugs 0.000 title abstract 2
- 229920001400 block copolymer Polymers 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229920000233 poly(alkylene oxides) Polymers 0.000 abstract 2
- 229920002635 polyurethane Polymers 0.000 abstract 2
- 239000004814 polyurethane Substances 0.000 abstract 2
- 201000009273 Endometriosis Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/001—Combinations of extrusion moulding with other shaping operations
- B29C48/0021—Combinations of extrusion moulding with other shaping operations combined with joining, lining or laminating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2033/00—Use of polymers of unsaturated acids or derivatives thereof as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/754—Pessaries
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Inorganic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Mechanical Engineering (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Materials For Medical Uses (AREA)
Abstract
Prezenta invenţie se bazează pe identificarea unei cohorte de copolimeri bloc poliuretanici care sunt deosebit de adecvaţi pentru utilizare în unităţi de medicamente polimerice farmaceutice şi care oferă un control îmbunătăţit al eliberării medicamentului. În particular, este prevăzută o unitate polimerică de medicament-dispozitiv care cuprinde un copolimer bloc poliuretanic care poate fi obţinut prin reacţia împreună a unui poli (alchilen oxid); un compus difuncţional; un izocianat difuncţional; şi opţional un copolimer bloc care cuprinde blocuri poli (oxid de alchilen); şi chinagolida ca agent farmaceutic activ. Unităţile de medicamente pot găsi aplicaţii în tratamentul şi / sau prevenirea endometriozei.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14192372.2A EP3017809A1 (en) | 2014-11-07 | 2014-11-07 | Drug-device unit containing quinagolide |
PCT/EP2015/075849 WO2016071466A1 (en) | 2014-11-07 | 2015-11-05 | Drug-device unit containing quinagolide |
Publications (1)
Publication Number | Publication Date |
---|---|
MD3215118T2 true MD3215118T2 (ro) | 2021-08-31 |
Family
ID=51951583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDE20170069T MD3215118T2 (ro) | 2014-11-07 | 2015-11-05 | Unitate de dispozitiv medical conţinând quinagolidă |
Country Status (33)
Country | Link |
---|---|
US (2) | US20180008535A1 (ro) |
EP (3) | EP3017809A1 (ro) |
JP (2) | JP6907120B2 (ro) |
KR (1) | KR102612852B1 (ro) |
CN (2) | CN116212032A (ro) |
AR (1) | AR102571A1 (ro) |
AU (2) | AU2015341734C1 (ro) |
CA (1) | CA2966473A1 (ro) |
CL (1) | CL2017001119A1 (ro) |
CO (1) | CO2017005578A2 (ro) |
DK (1) | DK3215118T3 (ro) |
EA (2) | EA033806B9 (ro) |
ES (1) | ES2877973T3 (ro) |
HR (1) | HRP20210961T1 (ro) |
HU (1) | HUE054951T2 (ro) |
IL (1) | IL252088B (ro) |
JO (1) | JO3561B1 (ro) |
LT (1) | LT3215118T (ro) |
MA (2) | MA40897B1 (ro) |
MD (1) | MD3215118T2 (ro) |
MX (1) | MX2017005828A (ro) |
MY (1) | MY193638A (ro) |
PH (1) | PH12017550005A1 (ro) |
PL (1) | PL3215118T3 (ro) |
PT (1) | PT3215118T (ro) |
RS (1) | RS62018B1 (ro) |
SA (1) | SA517381471B1 (ro) |
SG (1) | SG11201703596SA (ro) |
SI (1) | SI3215118T1 (ro) |
TN (1) | TN2017000175A1 (ro) |
TW (1) | TWI685339B (ro) |
UA (1) | UA122329C2 (ro) |
WO (1) | WO2016071466A1 (ro) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11896685B2 (en) | 2018-10-31 | 2024-02-13 | Amorepacific Corporation | Core-shell network structure comprising biopolymer and composition comprising same |
KR20210069344A (ko) | 2019-12-03 | 2021-06-11 | (주)아모레퍼시픽 | 바이오 폴리머를 포함하는 효능물질 전달체 |
WO2023031218A1 (en) | 2021-08-31 | 2023-03-09 | Ferring B.V. | Diagnosis and treatment of ectopic endometriosis |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235988A (en) | 1976-12-13 | 1980-11-25 | Imperial Chemical Industries Limited | Delivery means for biologically active agents |
JP4898431B2 (ja) | 2003-04-29 | 2012-03-14 | ザ ジェネラル ホスピタル コーポレイション | 複数薬物の持続放出のための方法およびデバイス |
WO2005004837A1 (en) | 2003-07-10 | 2005-01-20 | Galen (Chemicals) Limited | Intravaginal drug delivery devices |
EP1682102A2 (en) * | 2003-09-10 | 2006-07-26 | Noven Pharmaceuticals, Inc. | Multi-layer transdermal drug delivery device |
CA2605972C (en) | 2005-04-29 | 2011-08-02 | Ferring International Center S.A. | Treatment or prevention of ovarian hyperstimulation syndrome (ohss) using a dopamine agonist |
GB0613638D0 (en) * | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
SA08290041B1 (ar) | 2007-02-01 | 2012-06-05 | فيرينج انترناشونال سنتر اس آيه | أدوية من أجل معالجة بطانة الرحم |
EP2249811A1 (en) * | 2008-01-25 | 2010-11-17 | Grünenthal GmbH | Pharmaceutical dosage form |
WO2009094573A2 (en) | 2008-01-25 | 2009-07-30 | The University Of Utah Research Foundation | Linear order release polymer |
US20100040671A1 (en) | 2008-08-12 | 2010-02-18 | Ahmed Salah U | Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof |
US20100210600A1 (en) * | 2009-02-19 | 2010-08-19 | Prelief Inc. | Methods and Compositions for Treating Urogenital Disorders |
TW201102066A (en) * | 2009-06-26 | 2011-01-16 | Ferring Int Ct Sa | Treatment of endometriosis |
CA2795289A1 (en) * | 2010-04-08 | 2011-10-13 | Sanford-Burnham Medical Research Institute | Methods and compositions for enhanced delivery of compounds |
US9393311B2 (en) | 2010-11-15 | 2016-07-19 | Dsm Ip Assets B.V. | Intravaginal ring comprising polyurethane composition for drug delivery |
EP2734262B1 (en) * | 2011-07-20 | 2018-02-28 | Patrick F. Kiser | Intravaginal rings for drug delivery |
US10137199B2 (en) * | 2013-05-14 | 2018-11-27 | Biotime, Inc. | Thiolated hyaluronan-based hydrogels cross-linked using oxidized glutathione |
US10413504B2 (en) * | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
-
2014
- 2014-11-07 EP EP14192372.2A patent/EP3017809A1/en not_active Withdrawn
-
2015
- 2015-11-05 SI SI201531573T patent/SI3215118T1/sl unknown
- 2015-11-05 JP JP2017542330A patent/JP6907120B2/ja active Active
- 2015-11-05 AU AU2015341734A patent/AU2015341734C1/en active Active
- 2015-11-05 PL PL15790568T patent/PL3215118T3/pl unknown
- 2015-11-05 MX MX2017005828A patent/MX2017005828A/es unknown
- 2015-11-05 MY MYPI2017000673A patent/MY193638A/en unknown
- 2015-11-05 HU HUE15790568A patent/HUE054951T2/hu unknown
- 2015-11-05 MD MDE20170069T patent/MD3215118T2/ro unknown
- 2015-11-05 UA UAA201705500A patent/UA122329C2/uk unknown
- 2015-11-05 CN CN202310079847.2A patent/CN116212032A/zh active Pending
- 2015-11-05 PT PT157905688T patent/PT3215118T/pt unknown
- 2015-11-05 US US15/524,792 patent/US20180008535A1/en not_active Abandoned
- 2015-11-05 EP EP21162634.6A patent/EP3892261A1/en active Pending
- 2015-11-05 EA EA201790898A patent/EA033806B9/ru not_active IP Right Cessation
- 2015-11-05 SG SG11201703596SA patent/SG11201703596SA/en unknown
- 2015-11-05 EA EA201991882A patent/EA201991882A2/ru unknown
- 2015-11-05 CN CN201580067303.8A patent/CN106999422A/zh active Pending
- 2015-11-05 TN TN2017000175A patent/TN2017000175A1/en unknown
- 2015-11-05 RS RS20210767A patent/RS62018B1/sr unknown
- 2015-11-05 KR KR1020177015238A patent/KR102612852B1/ko active IP Right Grant
- 2015-11-05 JO JOP/2015/0276A patent/JO3561B1/ar active
- 2015-11-05 DK DK15790568.8T patent/DK3215118T3/da active
- 2015-11-05 MA MA40897A patent/MA40897B1/fr unknown
- 2015-11-05 WO PCT/EP2015/075849 patent/WO2016071466A1/en active Application Filing
- 2015-11-05 ES ES15790568T patent/ES2877973T3/es active Active
- 2015-11-05 CA CA2966473A patent/CA2966473A1/en active Pending
- 2015-11-05 LT LTEP15790568.8T patent/LT3215118T/lt unknown
- 2015-11-05 MA MA056414A patent/MA56414A/fr unknown
- 2015-11-05 EP EP15790568.8A patent/EP3215118B1/en active Active
- 2015-11-06 AR ARP150103620A patent/AR102571A1/es unknown
- 2015-11-06 TW TW104136694A patent/TWI685339B/zh active
-
2017
- 2017-05-03 IL IL252088A patent/IL252088B/en unknown
- 2017-05-05 PH PH12017550005A patent/PH12017550005A1/en unknown
- 2017-05-05 CL CL2017001119A patent/CL2017001119A1/es unknown
- 2017-05-06 SA SA517381471A patent/SA517381471B1/ar unknown
- 2017-06-05 CO CONC2017/0005578A patent/CO2017005578A2/es unknown
-
2020
- 2020-11-17 AU AU2020270480A patent/AU2020270480A1/en not_active Abandoned
-
2021
- 2021-05-10 US US17/316,208 patent/US20220040094A1/en not_active Abandoned
- 2021-06-16 HR HRP20210961TT patent/HRP20210961T1/hr unknown
- 2021-06-30 JP JP2021108386A patent/JP2021155444A/ja active Pending
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