RU93053493A - Сульфатная соль (2:1)-3-[2-(диметиламино)этил]-n-метил-1н-индол-5-метансульфонамида и ее фармацевтически приемлемые сольваты, способ их получения, фармацевтические композиции на их основе, их применение в терапии, способ лечения головной боли - Google Patents

Сульфатная соль (2:1)-3-[2-(диметиламино)этил]-n-метил-1н-индол-5-метансульфонамида и ее фармацевтически приемлемые сольваты, способ их получения, фармацевтические композиции на их основе, их применение в терапии, способ лечения головной боли

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Publication number
RU93053493A
RU93053493A RU93053493/04A RU93053493A RU93053493A RU 93053493 A RU93053493 A RU 93053493A RU 93053493/04 A RU93053493/04 A RU 93053493/04A RU 93053493 A RU93053493 A RU 93053493A RU 93053493 A RU93053493 A RU 93053493A
Authority
RU
Russia
Prior art keywords
current
methesulphonamide
inclusters
centuries
indol
Prior art date
Application number
RU93053493/04A
Other languages
English (en)
Other versions
RU2108328C1 (ru
Inventor
Крейг Джоанн
Лесли Крукс Дерек
Джон Скитролл Стивен
Original Assignee
Глэксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909026998A external-priority patent/GB9026998D0/en
Application filed by Глэксо Груп Лимитед filed Critical Глэксо Груп Лимитед
Publication of RU93053493A publication Critical patent/RU93053493A/ru
Application granted granted Critical
Publication of RU2108328C1 publication Critical patent/RU2108328C1/ru

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Claims (1)

  1. Соединение используют для получения фармацевтических композиций, в частности для интраназальных средств, для лечения состояний, связанных с головной болью, в частности мигрени.
RU93053493A 1990-12-12 1991-12-10 Сульфатная соль (2:1) 3-[2-(диметиламино)этил]-n-метил-1н-индол-5-метансульфонамида или ее фармацевтически приемлемые сольваты, способ их получения, фармацевтические композиции на их основе, способ лечения головной боли RU2108328C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9026998.6 1990-12-12
GB909026998A GB9026998D0 (en) 1990-12-12 1990-12-12 Medicaments
PCT/EP1991/002362 WO1992010477A1 (en) 1990-12-12 1991-12-10 Medicaments

Publications (2)

Publication Number Publication Date
RU93053493A true RU93053493A (ru) 1996-04-20
RU2108328C1 RU2108328C1 (ru) 1998-04-10

Family

ID=10686904

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93053493A RU2108328C1 (ru) 1990-12-12 1991-12-10 Сульфатная соль (2:1) 3-[2-(диметиламино)этил]-n-метил-1н-индол-5-метансульфонамида или ее фармацевтически приемлемые сольваты, способ их получения, фармацевтические композиции на их основе, способ лечения головной боли

Country Status (36)

Country Link
US (2) US5554639A (ru)
EP (1) EP0490689B1 (ru)
JP (1) JP2994037B2 (ru)
KR (1) KR100211479B1 (ru)
CN (2) CN1030890C (ru)
AP (1) AP230A (ru)
AT (1) ATE119881T1 (ru)
AU (1) AU650706B2 (ru)
BE (1) BE1005085A3 (ru)
CA (1) CA2098302C (ru)
CH (1) CH684192A5 (ru)
CY (1) CY2005A (ru)
CZ (1) CZ281931B6 (ru)
DE (1) DE69108200T2 (ru)
DK (1) DK0490689T3 (ru)
EG (1) EG20219A (ru)
ES (1) ES2069836T3 (ru)
FR (1) FR2670487B1 (ru)
GB (2) GB9026998D0 (ru)
GR (1) GR3015430T3 (ru)
HK (1) HK82697A (ru)
HU (1) HU211937A9 (ru)
IE (1) IE62894B1 (ru)
IL (1) IL100330A (ru)
IS (1) IS1706B (ru)
IT (1) IT1252868B (ru)
MX (1) MX9102501A (ru)
MY (1) MY109265A (ru)
NL (1) NL9102071A (ru)
NZ (1) NZ240942A (ru)
PT (1) PT99757B (ru)
RU (1) RU2108328C1 (ru)
TW (2) TW300886B (ru)
WO (1) WO1992010477A1 (ru)
YU (1) YU48926B (ru)
ZA (1) ZA919750B (ru)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0573221T3 (da) * 1992-06-05 1998-10-07 Merck Sharp & Dohme Sulfatsaltet af en substitueret triazol, farmaceutiske præparater deraf og deres anvendelse i terapi
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US8022095B2 (en) * 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6106837A (en) * 1997-05-15 2000-08-22 Hirsch; Alan R. Method of treating headaches, and article of manufacture therefor
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US6426084B1 (en) * 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6132757A (en) * 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
GB9926250D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Chemical process
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
US20030096748A1 (en) * 2001-06-04 2003-05-22 The Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US20030013753A1 (en) * 2001-06-05 2003-01-16 Ronald Aung-Din Transdermal migraine therapy
US8329734B2 (en) * 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US7208628B2 (en) * 2002-05-13 2007-04-24 Kansas State University Research Foundation Compositions and methods for the treatment of hepatitis C virus infection
US7074893B2 (en) * 2002-06-03 2006-07-11 Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
AU2003303631B2 (en) * 2002-12-26 2008-05-29 Nuvo Pharmaceuticals (Ireland) Designated Activity Company Multilayer Dosage Forms Containing NSAIDs and Triptans
US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
WO2004076403A1 (en) * 2003-02-24 2004-09-10 Transform Pharmaceuticals, Inc. Sumatriptan crystalline forms, pharmaceutical compositions and methods
CA2529528A1 (en) 2003-06-20 2004-12-29 Ronald Aung-Din Topical therapy for the treatment of migraines, muscle sprains, muscle spasm, spasticity and related conditions
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
WO2005119607A2 (en) * 2004-06-03 2005-12-15 Tyfone, Inc. System and method for securing financial transactions
EP1765300A2 (en) * 2004-06-10 2007-03-28 Duramed Pharmaceuticals, Inc. Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
JP2008545650A (ja) 2005-05-20 2008-12-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ スルファミド誘導体の製造方法
WO2007070504A2 (en) * 2005-12-13 2007-06-21 Morton Grove Pharmaceuticals, Inc. Stable and palatable oral liquid sumatriptan compositions
US8492431B2 (en) 2005-12-19 2013-07-23 Janssen Pharmaceutica, N.V. Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US20070191461A1 (en) * 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of migraine
EA200870556A1 (ru) 2006-05-19 2009-06-30 Янссен Фармацевтика Н.В. Комбинированная терапия в лечении эпилепсии и родственных расстройств
JP2010522135A (ja) 2006-10-09 2010-07-01 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
EP2081893B1 (en) * 2006-10-19 2011-03-23 Auspex Pharmaceuticals, Inc. Substituted indoles
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
GB2448183A (en) * 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
JP5714910B2 (ja) 2008-01-09 2015-05-07 チャールストン ラボラトリーズ，インコーポレイテッド 薬学的組成物
US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
KR20110019759A (ko) 2008-05-27 2011-02-28 비오타 사이언티픽 매니지먼트 피티와이 엘티디 항바이러스 염
AU2009260166B2 (en) * 2008-06-20 2014-10-09 Alphapharm Pty Ltd Pharmaceutical formulation
NZ590682A (en) 2008-06-23 2012-09-28 Janssen Pharmaceutica Nv Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide
JP2011526889A (ja) * 2008-06-30 2011-10-20 アフギン ファーマ，エルエルシー 局所局部的神経作用療法
US8815939B2 (en) 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
DK2480197T3 (en) * 2009-09-25 2016-01-25 Reddys Lab Ltd Dr Compositions containing triptanforbindelser
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
CA2978605A1 (en) 2015-03-02 2016-09-09 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoids
WO2016187013A1 (en) 2015-05-15 2016-11-24 The Regents Of The University Of Michigan Methods and compositions for the treatment of arthritis
US10179109B2 (en) 2016-03-04 2019-01-15 Charleston Laboratories, Inc. Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene
CA3079848A1 (en) 2017-11-07 2019-05-16 The Regents Of The University Of Michigan Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use
US20220096438A1 (en) 2018-09-07 2022-03-31 Upsher-Smith Laboratories, Llc Methods of treating migraine
US11364225B2 (en) * 2019-08-21 2022-06-21 Bn Intellectual Properties, Inc. Pharmaceutical formulation for treating symptoms of migraine and cluster headaches, and method of using the same
AU2021227937A1 (en) * 2020-02-27 2022-09-08 Biohaven Pharmaceutical Holding Company Ltd. Oral fast-dispersing dosage form of rimegepant

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
GB8928208D0 (en) * 1989-12-13 1990-02-14 Glaxo Group Ltd Medicaments

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