RU2680096C2 - Липосомальные препараты - Google Patents

Липосомальные препараты Download PDF

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RU2680096C2
RU2680096C2 RU2015107317A RU2015107317A RU2680096C2 RU 2680096 C2 RU2680096 C2 RU 2680096C2 RU 2015107317 A RU2015107317 A RU 2015107317A RU 2015107317 A RU2015107317 A RU 2015107317A RU 2680096 C2 RU2680096 C2 RU 2680096C2
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Russia
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peg
eye
self
liposome
thermodynamically stable
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RU2015107317A
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English (en)
Russian (ru)
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RU2015107317A (ru
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Артуро Сантос
Филлип ФРОСТ
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ОПКО ФАРМАСЬЮТИКАЛС, Эл Эл Си
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50150466&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2680096(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ОПКО ФАРМАСЬЮТИКАЛС, Эл Эл Си filed Critical ОПКО ФАРМАСЬЮТИКАЛС, Эл Эл Си
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
RU2015107317A 2012-08-21 2013-08-15 Липосомальные препараты RU2680096C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261691455P 2012-08-21 2012-08-21
US61/691,455 2012-08-21
US201361791693P 2013-03-15 2013-03-15
US61/791,693 2013-03-15
US201361862300P 2013-08-05 2013-08-05
US61/862,300 2013-08-05
PCT/US2013/055084 WO2014031429A2 (en) 2012-08-21 2013-08-15 Liposome formulations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2019103521A Division RU2817350C2 (ru) 2012-08-21 2013-08-15 Липосомальные препараты

Publications (2)

Publication Number Publication Date
RU2015107317A RU2015107317A (ru) 2016-10-10
RU2680096C2 true RU2680096C2 (ru) 2019-02-15

Family

ID=50150466

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015107317A RU2680096C2 (ru) 2012-08-21 2013-08-15 Липосомальные препараты

Country Status (16)

Country Link
US (2) US10548841B2 (enExample)
EP (1) EP2887958B1 (enExample)
JP (3) JP6336448B2 (enExample)
KR (2) KR102177437B1 (enExample)
CN (1) CN104582728A (enExample)
AR (1) AR092372A1 (enExample)
BR (1) BR112015003658B1 (enExample)
CA (2) CA3098856C (enExample)
CL (1) CL2015000418A1 (enExample)
ES (1) ES2881671T3 (enExample)
HU (1) HUE058912T2 (enExample)
MX (2) MX363822B (enExample)
PL (1) PL2887958T3 (enExample)
RU (1) RU2680096C2 (enExample)
TW (2) TWI608848B (enExample)
WO (1) WO2014031429A2 (enExample)

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RU2676303C2 (ru) * 2013-07-11 2018-12-27 Новартис Аг Использование антагониста vegf для лечения ретролентальной фиброплазии
RU2016127357A (ru) * 2013-12-19 2018-01-24 Ф. Хоффманн-Ля Рош Аг Модулятор сетр для применения в лечении заболеваний глаз
EP3145532A4 (en) * 2014-05-02 2018-02-21 Mayo Foundation for Medical Education and Research Individualized treatment of eye disease
KR101778004B1 (ko) 2015-06-22 2017-09-15 (주) 에빅스젠 이마티닙을 유효성분으로 포함하는 안구 건조 질환 예방 및 치료용 약학 조성물
AR106690A1 (es) * 2015-11-13 2018-02-07 Ohr Pharmaceutical Inc Método para administrar escualamina o una sal farmacéuticamente aceptable a la esclerótica posterior y a la coroides del ojo
CN119770646A (zh) * 2018-02-06 2025-04-08 豪夫迈·罗氏有限公司 眼科疾病的治疗
KR20210096592A (ko) * 2018-08-23 2021-08-05 번스타인, 에릭, 에프 피부 질환을 치료하기 위해 항-vegf 화합물을 도포하고 이러한 화합물을 이용하기 위한 시스템, 장치, 및 방법
CN109180798B (zh) * 2018-09-04 2020-10-27 武汉原生药谷生物医药科技有限公司 一种增强型治疗性抗体及其应用
KR102467349B1 (ko) 2018-10-29 2022-11-16 에프. 호프만-라 로슈 아게 항체 제형
US20200323882A1 (en) * 2019-03-15 2020-10-15 University Of Rhode Island Board Of Trustees Phlip®-mediated targeting of corticosteroids to diseased tissue
EP3968949A1 (en) 2019-05-16 2022-03-23 OPKO Pharmaceuticals, LLC Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations for prevention of macular thickening and its associated visual outcomes after lens surgery
KR20250051157A (ko) 2019-06-05 2025-04-16 리제너론 파아마슈티컬스, 인크. 정밀 투여량 전달을 위한 디바이스 및 방법
CN113546172A (zh) * 2020-04-24 2021-10-26 山东大学齐鲁医院 Vegf抑制剂在制备治疗缺氧相关疾病药物中的应用
MX2022015656A (es) * 2020-06-15 2023-03-22 Opko Pharmaceuticals Llc Formulaciones oftalmaticas topicas de liposomas cargados con acetonido de triamcinolona como terapia primaria para el edema macular secundario a la oclusion de la vena retiniana de rama.
CN116585304B (zh) * 2023-04-25 2024-04-05 四川大学华西医院 一种急性肝损伤保护药物及其制备方法
WO2025146683A1 (en) 2024-01-03 2025-07-10 Lyotropic Delivery Systems Ltd. Topical formulations for delivery of an active compound to the back of the eye
CN119701010B (zh) * 2024-12-25 2025-10-28 山东第一医科大学附属眼科医院(山东省眼科医院) 一种基于中性粒细胞纳米囊泡的抗炎和抗血管双向诱捕联合自发光动力的复合物及其制备方法和应用

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US6958160B1 (en) * 2000-12-20 2005-10-25 Biozone Technologies, Inc. Self forming, thermodynamically stable liposomes and their applications
US20060165744A1 (en) * 2003-05-22 2006-07-27 Neopharm, Inc Combination liposomal formulations
US20110097340A1 (en) * 2007-10-22 2011-04-28 Sumant Ramachandra Fully human anti-vegf antibodies and methods of using
US20120009185A1 (en) * 2006-11-10 2012-01-12 Genentech, Inc. Method for treating age-related macular degeneration

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