RU2669921C2 - Композиция, содержащая ингибиторы котранспортеров натрия-глюкозы 1 и 2, и способы их применения - Google Patents

Композиция, содержащая ингибиторы котранспортеров натрия-глюкозы 1 и 2, и способы их применения Download PDF

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RU2669921C2
RU2669921C2 RU2013136384A RU2013136384A RU2669921C2 RU 2669921 C2 RU2669921 C2 RU 2669921C2 RU 2013136384 A RU2013136384 A RU 2013136384A RU 2013136384 A RU2013136384 A RU 2013136384A RU 2669921 C2 RU2669921 C2 RU 2669921C2
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chloro
phenyl
ethoxybenzyl
triol
compounds
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RU2013136384A
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Russian (ru)
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RU2013136384A (ru
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Цзиньлин ЧЭНЬ
Нассер Н. НИАМВЕИА
Кеннет К. Х. ОНГ
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Лексикон Фармасьютикалз, Инк.
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    • A61K31/13—Amines
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RU2013136384A 2011-01-05 2012-01-03 Композиция, содержащая ингибиторы котранспортеров натрия-глюкозы 1 и 2, и способы их применения RU2669921C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161430027P 2011-01-05 2011-01-05
US61/430,027 2011-01-05
PCT/US2012/020042 WO2012094293A1 (en) 2011-01-05 2012-01-03 Compositions comprising and methods of using inhibitors of sodium-glucose cotransporters 1 and 2

Publications (2)

Publication Number Publication Date
RU2013136384A RU2013136384A (ru) 2015-02-10
RU2669921C2 true RU2669921C2 (ru) 2018-10-17

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RU2013136384A RU2669921C2 (ru) 2011-01-05 2012-01-03 Композиция, содержащая ингибиторы котранспортеров натрия-глюкозы 1 и 2, и способы их применения

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US (6) US20120172320A1 (enExample)
EP (1) EP2661256B1 (enExample)
JP (3) JP2014501780A (enExample)
KR (1) KR102024204B1 (enExample)
CN (1) CN103458875A (enExample)
AR (1) AR084781A1 (enExample)
AU (1) AU2012204567B9 (enExample)
BR (1) BR112013017314B1 (enExample)
CA (1) CA2823736C (enExample)
DK (1) DK2661256T3 (enExample)
ES (1) ES2710341T3 (enExample)
HU (1) HUE041364T2 (enExample)
IL (1) IL295438B2 (enExample)
MX (1) MX360554B (enExample)
PL (1) PL2661256T3 (enExample)
PT (1) PT2661256T (enExample)
RU (1) RU2669921C2 (enExample)
SG (2) SG10201602670QA (enExample)
TR (1) TR201901262T4 (enExample)
TW (1) TWI631963B (enExample)
WO (1) WO2012094293A1 (enExample)
ZA (1) ZA201304694B (enExample)

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TR201908247T4 (tr) * 2012-11-20 2019-06-21 Lexicon Pharmaceuticals Inc Sodyum glikoz birlikte taşıyıcı 1 inhibitörleri.
JP6727419B2 (ja) * 2016-05-25 2020-07-22 クリスタル ファーマシューティカル（スーチョウ）カンパニー，リミテッド ナトリウム−グルコース共輸送体阻害薬の新規な結晶形及びその製造方法並びに用途
US11723929B2 (en) 2017-06-13 2023-08-15 The Regents Of The University Of California Methods of improving cell-based therapy
CN107540685B (zh) * 2017-09-04 2020-05-05 杭州科巢生物科技有限公司 一种Sotagliflozin的制备方法及其中间体
EP3456320A1 (de) * 2017-09-15 2019-03-20 Stada Arzneimittel Ag Dpp-4-inhibitor-mono-zusammensetzung
FI3712147T3 (fi) * 2018-01-05 2023-04-04 Shangdong Danhong Pharmaceutical Co Ltd Sglts-estäjä ja sen käyttö
CN110117304A (zh) * 2018-04-23 2019-08-13 中国科学院成都生物研究所 一种钠-葡萄糖协同转运蛋白1和2抑制剂的药物用途
CN110818722B (zh) * 2018-08-14 2022-12-02 苏州鹏旭医药科技有限公司 三种化合物及其制备方法和在合成索格列净中的用途
CN113993865B (zh) 2019-07-05 2023-09-22 山东丹红制药有限公司 一种SGLTs抑制剂的晶型及其应用
CA3145678C (en) * 2019-07-26 2022-08-23 Medshine Discovery Inc. Sglt2/dpp4 inhibitor and application thereof
CN114585358B (zh) 2019-07-26 2023-11-10 东宝紫星(杭州)生物医药有限公司 一种SGLTs/DPP4抑制剂及其应用
EP3771480A1 (en) * 2019-08-01 2021-02-03 Lexicon Pharmaceuticals, Inc. Continuous process for preparing the crystalline form ii of sotagliflozin
EP4054556A4 (en) * 2019-11-07 2023-11-29 Increvet, Inc. SODIUM-GLUCOSE-LINKED TRANSPORTER INHIBITORS FOR THE MANAGEMENT OF CHRONIC KIDNEY DISEASE, HYPERTENSION AND HEART FAILURE IN PETS
US20240100013A1 (en) 2021-01-04 2024-03-28 Lexicon Pharmaceuticals, Inc. Sotagliflozin for improving left atrial function
WO2022155303A1 (en) 2021-01-14 2022-07-21 Lexicon Pharmaceuticals, Inc. Sotagliflozin for treating or preventing cardiovascular diseases
KR20260083316A (ko) 2023-09-28 2026-06-05 렉시컨 파마슈티컬스 인코퍼레이티드 제1형 당뇨병 및 신장 질환을 치료하는 방법
US20250114323A1 (en) 2023-10-06 2025-04-10 Lexicon Pharmaceuticals, Inc. Methods of reducing the risk of cardiovascular events in patients with left ventricular hypertrophy

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