TR201901262T4 - (2S,3R,4R,5S,6R)-2-(4-Kloro-3-(4-Etoksibenzil)Fenil)-6-(Metiltiyo)Tetrahidro-2H-Piran-3,4,5-Triol İçeren Bileşimler - Google Patents

(2S,3R,4R,5S,6R)-2-(4-Kloro-3-(4-Etoksibenzil)Fenil)-6-(Metiltiyo)Tetrahidro-2H-Piran-3,4,5-Triol İçeren Bileşimler Download PDF

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Publication number
TR201901262T4
TR201901262T4 TR2019/01262T TR201901262T TR201901262T4 TR 201901262 T4 TR201901262 T4 TR 201901262T4 TR 2019/01262 T TR2019/01262 T TR 2019/01262T TR 201901262 T TR201901262 T TR 201901262T TR 201901262 T4 TR201901262 T4 TR 201901262T4
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Turkey
Prior art keywords
ethoxybenzyl
triol
pyran
methylthio
tetrahydro
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TR2019/01262T
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English (en)
Inventor
Chen Jinling
N Nyamweya Nasser
K H Ong Kenneth
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Lexicon Pharmaceuticals Inc
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Application filed by Lexicon Pharmaceuticals Inc filed Critical Lexicon Pharmaceuticals Inc
Publication of TR201901262T4 publication Critical patent/TR201901262T4/tr

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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Hastaların, özellikle tip 2 diyabetli hastaların kardiyovasküler ve/veya metabolik sağlığının iyileştirilmesi için yararlı farmasötik dozaj formlarının yanı sıra bunların üretim usulleri açıklanmaktadır.
TR2019/01262T 2011-01-05 2012-01-03 (2S,3R,4R,5S,6R)-2-(4-Kloro-3-(4-Etoksibenzil)Fenil)-6-(Metiltiyo)Tetrahidro-2H-Piran-3,4,5-Triol İçeren Bileşimler TR201901262T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161430027P 2011-01-05 2011-01-05

Publications (1)

Publication Number Publication Date
TR201901262T4 true TR201901262T4 (tr) 2019-02-21

Family

ID=45507917

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TR2019/01262T TR201901262T4 (tr) 2011-01-05 2012-01-03 (2S,3R,4R,5S,6R)-2-(4-Kloro-3-(4-Etoksibenzil)Fenil)-6-(Metiltiyo)Tetrahidro-2H-Piran-3,4,5-Triol İçeren Bileşimler

Country Status (22)

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US (6) US20120172320A1 (tr)
EP (1) EP2661256B1 (tr)
JP (3) JP2014501780A (tr)
KR (1) KR102024204B1 (tr)
CN (1) CN103458875A (tr)
AR (1) AR084781A1 (tr)
AU (1) AU2012204567B9 (tr)
BR (1) BR112013017314B1 (tr)
CA (1) CA2823736C (tr)
DK (1) DK2661256T3 (tr)
ES (1) ES2710341T3 (tr)
HU (1) HUE041364T2 (tr)
IL (1) IL295438A (tr)
MX (1) MX360554B (tr)
PL (1) PL2661256T3 (tr)
PT (1) PT2661256T (tr)
RU (1) RU2669921C2 (tr)
SG (2) SG191865A1 (tr)
TR (1) TR201901262T4 (tr)
TW (1) TWI631963B (tr)
WO (1) WO2012094293A1 (tr)
ZA (1) ZA201304694B (tr)

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US11723929B2 (en) 2017-06-13 2023-08-15 The Regents Of The University Of California Methods of improving cell-based therapy
CN107540685B (zh) * 2017-09-04 2020-05-05 杭州科巢生物科技有限公司 一种Sotagliflozin的制备方法及其中间体
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FI3712147T3 (fi) * 2018-01-05 2023-04-04 Shangdong Danhong Pharmaceutical Co Ltd Sglts-estäjä ja sen käyttö
CN110117304A (zh) * 2018-04-23 2019-08-13 中国科学院成都生物研究所 一种钠-葡萄糖协同转运蛋白1和2抑制剂的药物用途
CN110818722B (zh) * 2018-08-14 2022-12-02 苏州鹏旭医药科技有限公司 三种化合物及其制备方法和在合成索格列净中的用途
US20220324897A1 (en) 2019-07-05 2022-10-13 Shandong Danhong Pharmaceutical Co., Ltd. Crystal form of sglt inhibitor and application thereof
MX2022001029A (es) 2019-07-26 2022-05-24 Dongbao Purple Star Hangzhou Biopharmaceutical Co Ltd Inhibidor de sglts/dpp4 y aplicación del mismo.
JP2022554344A (ja) * 2019-11-07 2022-12-28 インクレベット，インコーポレイティド コンパニオンアニマルにおける慢性腎疾患、高血圧、及び心不全の管理のためのナトリウム－グルコース共輸送体阻害剤
US20240100013A1 (en) 2021-01-04 2024-03-28 Lexicon Pharmaceuticals, Inc. Sotagliflozin for improving left atrial function
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