RU2662810C2 - Хиназолины в качестве ингибиторов киназы - Google Patents

Хиназолины в качестве ингибиторов киназы Download PDF

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RU2662810C2
RU2662810C2 RU2015139758A RU2015139758A RU2662810C2 RU 2662810 C2 RU2662810 C2 RU 2662810C2 RU 2015139758 A RU2015139758 A RU 2015139758A RU 2015139758 A RU2015139758 A RU 2015139758A RU 2662810 C2 RU2662810 C2 RU 2662810C2
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disease
compound
pharmaceutically acceptable
acceptable salt
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RU2015139758A (ru
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Линда Н. Касиллас
Адам Кеннет Чарнли
Сяоян Дун
Памела А. Хейл
Майкл П. Демартино
Джон Ф. Мелманн
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Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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RU2015139758A 2013-02-21 2014-02-19 Хиназолины в качестве ингибиторов киназы RU2662810C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361767423P 2013-02-21 2013-02-21
US61/767,423 2013-02-21
PCT/IB2014/059094 WO2014128622A1 (en) 2013-02-21 2014-02-19 Quinazolines as kinase inhibitors

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Publication Number Publication Date
RU2015139758A RU2015139758A (ru) 2017-03-24
RU2662810C2 true RU2662810C2 (ru) 2018-07-31

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US (1) US9650364B2 (enExample)
EP (1) EP2958911B1 (enExample)
JP (1) JP6301374B2 (enExample)
KR (1) KR20150118152A (enExample)
CN (1) CN105143208B (enExample)
AR (1) AR094707A1 (enExample)
AU (1) AU2014220300B2 (enExample)
BR (1) BR112015019624A2 (enExample)
CA (1) CA2902132C (enExample)
ES (1) ES2654100T3 (enExample)
RU (1) RU2662810C2 (enExample)
TW (1) TWI630203B (enExample)
WO (1) WO2014128622A1 (enExample)

Families Citing this family (10)

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KR101940340B1 (ko) 2011-03-04 2019-01-18 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 키나제 억제제로서의 아미노-퀴놀린
TWI547494B (zh) 2011-08-18 2016-09-01 葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之胺基喹唑啉類
AR092529A1 (es) 2012-09-13 2015-04-22 Glaxosmithkline Llc Compuesto de aminoquinazolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
AR092530A1 (es) 2012-09-13 2015-04-22 Glaxosmithkline Llc Compuesto de amino-quinolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
BR112015019624A2 (pt) 2013-02-21 2017-07-18 Glaxosmithkline Ip Dev Ltd quinazolinas como inibidores de quinase
GB201506872D0 (en) 2015-04-22 2015-06-03 Ge Oil & Gas Uk Ltd Novel compounds
GB201516243D0 (en) 2015-09-14 2015-10-28 Glaxosmithkline Ip Dev Ltd Novel compounds
JP2019514878A (ja) 2016-04-20 2019-06-06 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Ripk2阻害剤を含むコンジュゲート
WO2020043122A1 (zh) * 2018-08-28 2020-03-05 南京明德新药研发有限公司 作为rip2激酶抑制剂的喹唑啉类衍生物
WO2025092821A1 (zh) * 2023-11-01 2025-05-08 成都赜灵生物医药科技有限公司 喹唑啉衍生物类ripk2抑制剂及其用途

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