CA2902132C - Quinazolines as kinase inhibitors - Google Patents
Quinazolines as kinase inhibitors Download PDFInfo
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- CA2902132C CA2902132C CA2902132A CA2902132A CA2902132C CA 2902132 C CA2902132 C CA 2902132C CA 2902132 A CA2902132 A CA 2902132A CA 2902132 A CA2902132 A CA 2902132A CA 2902132 C CA2902132 C CA 2902132C
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- disease
- compound
- pharmaceutically acceptable
- sarcoidosis
- tert
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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Landscapes
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| US201361767423P | 2013-02-21 | 2013-02-21 | |
| US61/767,423 | 2013-02-21 | ||
| PCT/IB2014/059094 WO2014128622A1 (en) | 2013-02-21 | 2014-02-19 | Quinazolines as kinase inhibitors |
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| CA2902132A1 CA2902132A1 (en) | 2014-08-28 |
| CA2902132C true CA2902132C (en) | 2020-09-22 |
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| JP (1) | JP6301374B2 (enExample) |
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| EA023998B1 (ru) | 2011-03-04 | 2016-08-31 | Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Аминохинолины в качестве ингибиторов киназ |
| TWI547494B (zh) | 2011-08-18 | 2016-09-01 | 葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之胺基喹唑啉類 |
| TWI592417B (zh) | 2012-09-13 | 2017-07-21 | 葛蘭素史克智慧財產發展有限公司 | 胺基喹唑啉激酶抑制劑之前藥 |
| AR092530A1 (es) | 2012-09-13 | 2015-04-22 | Glaxosmithkline Llc | Compuesto de amino-quinolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento |
| TWI630203B (zh) | 2013-02-21 | 2018-07-21 | 葛蘭素史克智慧財產發展有限公司 | 做為激酶抑制劑的喹唑啉類 |
| GB201506872D0 (en) | 2015-04-22 | 2015-06-03 | Ge Oil & Gas Uk Ltd | Novel compounds |
| GB201516243D0 (en) | 2015-09-14 | 2015-10-28 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| US10781205B2 (en) * | 2016-04-20 | 2020-09-22 | Glaxosmithkline Intellectual Property Development Limited | Conjugates comprising RIPK2 inhibitors |
| WO2020043122A1 (zh) * | 2018-08-28 | 2020-03-05 | 南京明德新药研发有限公司 | 作为rip2激酶抑制剂的喹唑啉类衍生物 |
| WO2025092821A1 (zh) * | 2023-11-01 | 2025-05-08 | 成都赜灵生物医药科技有限公司 | 喹唑啉衍生物类ripk2抑制剂及其用途 |
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| US4916135A (en) | 1989-05-08 | 1990-04-10 | Hoechst Roussel Pharmaceuticals Inc. | N-heteroaryl-4-quinolinamines |
| US5710158A (en) * | 1991-05-10 | 1998-01-20 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| PT100905A (pt) | 1991-09-30 | 1994-02-28 | Eisai Co Ltd | Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem |
| AU661533B2 (en) | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
| GB9510757D0 (en) | 1994-09-19 | 1995-07-19 | Wellcome Found | Therapeuticaly active compounds |
| US5747498A (en) | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
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- 2014-02-19 CN CN201480009917.6A patent/CN105143208B/zh not_active Expired - Fee Related
- 2014-02-19 CA CA2902132A patent/CA2902132C/en not_active Expired - Fee Related
- 2014-02-19 ES ES14708681.3T patent/ES2654100T3/es active Active
- 2014-02-19 EP EP14708681.3A patent/EP2958911B1/en active Active
- 2014-02-19 AR ARP140100520A patent/AR094707A1/es unknown
- 2014-02-19 US US14/762,905 patent/US9650364B2/en not_active Expired - Fee Related
- 2014-02-19 JP JP2015558582A patent/JP6301374B2/ja not_active Expired - Fee Related
- 2014-02-19 BR BR112015019624A patent/BR112015019624A2/pt not_active Application Discontinuation
- 2014-02-19 AU AU2014220300A patent/AU2014220300B2/en not_active Ceased
- 2014-02-19 WO PCT/IB2014/059094 patent/WO2014128622A1/en not_active Ceased
- 2014-02-19 KR KR1020157022263A patent/KR20150118152A/ko not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| CN105143208A (zh) | 2015-12-09 |
| AU2014220300A1 (en) | 2015-08-06 |
| AR094707A1 (es) | 2015-08-19 |
| US20150361069A1 (en) | 2015-12-17 |
| TWI630203B (zh) | 2018-07-21 |
| WO2014128622A1 (en) | 2014-08-28 |
| EP2958911B1 (en) | 2017-10-18 |
| ES2654100T3 (es) | 2018-02-12 |
| RU2015139758A (ru) | 2017-03-24 |
| TW201444824A (zh) | 2014-12-01 |
| RU2662810C2 (ru) | 2018-07-31 |
| JP2016509051A (ja) | 2016-03-24 |
| CA2902132A1 (en) | 2014-08-28 |
| CN105143208B (zh) | 2017-09-26 |
| AU2014220300B2 (en) | 2016-10-13 |
| JP6301374B2 (ja) | 2018-03-28 |
| EP2958911A1 (en) | 2015-12-30 |
| KR20150118152A (ko) | 2015-10-21 |
| US9650364B2 (en) | 2017-05-16 |
| BR112015019624A2 (pt) | 2017-07-18 |
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