RU2643138C2 - Система и способ аддитивного производства трехмерных структур - Google Patents

Система и способ аддитивного производства трехмерных структур Download PDF

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RU2643138C2
RU2643138C2 RU2016100442A RU2016100442A RU2643138C2 RU 2643138 C2 RU2643138 C2 RU 2643138C2 RU 2016100442 A RU2016100442 A RU 2016100442A RU 2016100442 A RU2016100442 A RU 2016100442A RU 2643138 C2 RU2643138 C2 RU 2643138C2
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print head
channels
materials
receiving surface
hydrogel
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RU2016100442A
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Russian (ru)
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RU2016100442A (ru
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Симон Травис БЕЙЕР
Конрад ВАЛУС
Тамер МОХАМЕД
Анас Амхад Мохаммад БСОУЛ
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Аспект Биосистемс Лтд.
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/112—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/015—Ink jet characterised by the jet generation process
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B29C64/205—Means for applying layers
    • B29C64/209—Heads; Nozzles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30—Auxiliary operations or equipment
    • B29C64/386—Data acquisition or data processing for additive manufacturing
    • B29C64/393—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058—Liquid or visquous
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058—Liquid or visquous
    • B29K2105/0061—Gel or sol
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00—Data acquisition or data processing for additive manufacturing
    • B33Y50/02—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Sustainable Development (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Composite Materials (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Coating Apparatus (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
RU2016100442A 2013-06-13 2014-06-13 Система и способ аддитивного производства трехмерных структур RU2643138C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361834420P 2013-06-13 2013-06-13
US61/834,420 2013-06-13
PCT/CA2014/050556 WO2014197999A1 (en) 2013-06-13 2014-06-13 System for additive manufacturing of three-dimensional structures and method for same

Publications (2)

Publication Number Publication Date
RU2016100442A RU2016100442A (ru) 2017-07-18
RU2643138C2 true RU2643138C2 (ru) 2018-01-30

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RU2016100442A RU2643138C2 (ru) 2013-06-13 2014-06-13 Система и способ аддитивного производства трехмерных структур

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US (3) US11046930B2 (enExample)
EP (3) EP3007882B1 (enExample)
JP (5) JP6550379B2 (enExample)
KR (2) KR102284531B1 (enExample)
CN (1) CN105579219B (enExample)
AU (1) AU2014280825B2 (enExample)
BR (1) BR112015031320B1 (enExample)
CA (1) CA2915737C (enExample)
DK (2) DK3007882T3 (enExample)
ES (2) ES3035595T3 (enExample)
FI (1) FI3670155T3 (enExample)
IL (1) IL243014B (enExample)
PL (2) PL3670155T3 (enExample)
PT (2) PT3007882T (enExample)
RU (1) RU2643138C2 (enExample)
SG (1) SG11201510138RA (enExample)
WO (1) WO2014197999A1 (enExample)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140039662A1 (en) * 2012-07-31 2014-02-06 Makerbot Industries, Llc Augmented three-dimensional printing
FI3670155T3 (fi) 2013-06-13 2025-07-17 Aspect Biosystems Ltd Tulostuspää, järjestelmä kolmiulotteisten rakenteiden lisävalmistusta varten ja menetelmä siihen
WO2015066705A1 (en) * 2013-11-04 2015-05-07 University Of Iowa Research Foundation Bioprinter and methods of using same
EP3536377A1 (en) 2014-02-26 2019-09-11 Luma Therapeutics, Inc. Ultraviolet phototherapy apparatus
US20160318260A1 (en) * 2015-04-30 2016-11-03 Elwha Llc Printing systems and related methods
DE102015206813A1 (de) * 2015-04-15 2016-10-20 Robert Bosch Gmbh Vorrichtung und Verfahren zum Auftragen eines Fluids auf einen Werkstückträger zum Erzeugen eines Werkstücks und System zum Erzeugen eines Werkstücks
US10961492B2 (en) * 2015-04-29 2021-03-30 Politecnico Di Milano Microfluidic devices and related methods for generation and/or culture and/or maturation of three-dimensional cells and/or tissue constructs
EP3302442B1 (en) 2015-06-03 2024-10-16 Triastek, Inc. Dosage forms and use thereof
WO2016201577A1 (en) 2015-06-16 2016-12-22 Aspect Biosystems Ltd. Continuously bioprinted multilayer tissue structure
WO2017048861A1 (en) 2015-09-16 2017-03-23 Applied Materials, Inc. Printhead module for additive manufacturing system
JP2018530672A (ja) * 2015-09-16 2018-10-18 アプライド マテリアルズ インコーポレイテッドＡｐｐｌｉｅｄ Ｍａｔｅｒｉａｌｓ，Ｉｎｃｏｒｐｏｒａｔｅｄ 付加製造システムのためのプリントヘッドモジュールのアレイ
EP3383997A4 (en) 2015-12-04 2019-11-27 Emulate, Inc. TOP OPEN MICROFLUIDIC DEVICE WITH STRUCTURAL ANCHOR
US10026674B2 (en) 2015-12-22 2018-07-17 Raytheon Company Cooling structure for integrated circuits and methods for forming such structure
WO2017113161A1 (zh) * 2015-12-30 2017-07-06 四川蓝光英诺生物科技股份有限公司 生物打印机喷头组件及生物打印机
WO2017130739A1 (ja) * 2016-01-25 2017-08-03 株式会社リコー 立体造形物、立体造形物の製造方法、立体造形物の製造装置、立体造形用材料セット、及びハイドロゲル前駆体液
AU2017217839A1 (en) 2016-02-09 2018-08-23 Luma Therapeutics, Inc. Methods, compositions and apparatuses for treating psoriasis by phototherapy
WO2017192004A1 (ko) * 2016-05-03 2017-11-09 주식회사 티앤알바이오팹 삼차원 프린팅용 잉크를 공급하는 방법 및 이를 이용한 삼차원 프린팅 방법
JP6898353B2 (ja) 2016-05-03 2021-07-07 ティーアンドアール バイオファブ カンパニー リミテッドＴ ＆ Ｒ Ｂｉｏｆａｂ Ｃｏ．， Ｌｔｄ． 三次元プリンティング用インクを供給する方法およびこれを用いた三次元印刷方法
US10926454B2 (en) * 2016-05-20 2021-02-23 Sartorius Stedim Biotech Gmbh Dispensing device and system for biological products
GB201609764D0 (en) 2016-06-03 2016-07-20 Isis Innovation 3D printing of gel networks
SG11201811226PA (en) 2016-06-16 2019-01-30 Aspect Biosystems Ltd Bioprinted meniscus implant and methods of using same
WO2018009943A2 (en) 2016-07-08 2018-01-11 Cypre, Inc. Apparatus for patterning hydrogels into multi-well plates
WO2018013727A1 (en) 2016-07-12 2018-01-18 Deka Products Limited Partnership System and method for applying force to a device
USD812766S1 (en) * 2016-07-12 2018-03-13 EMULATE, Inc. Microfluidic chip for use with a fluid perfusion module
US11254901B2 (en) 2016-07-12 2022-02-22 Deka Products Limited Partnership System and method for printing tissue
CN109890619B (zh) 2016-07-27 2021-01-26 哈佛学院院长及董事 用于声泳打印的设备和方法
US20180056586A1 (en) * 2016-08-26 2018-03-01 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Tailored Multi-Material Delivery for Direct-Write Manufacturing
USD816861S1 (en) * 2016-09-07 2018-05-01 EMULATE, Inc. Transparent microfluidic chip without pressure features for use with a fluid perfusion module
USD842493S1 (en) * 2016-09-07 2019-03-05 EMULATE, Inc. Microfluidic chip without pressure features for use with a fluid perfusion module
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
WO2018106707A1 (en) * 2016-12-07 2018-06-14 President And Fellows Of Harvard College Valved nozzle with a compensator and massively parallel 3d printing system
DE102016225227B4 (de) * 2016-12-16 2025-04-30 Robert Bosch Gmbh Verfahren zum additiven Fertigen eines dreidimensionalen Objekts
CN106510898A (zh) * 2016-12-21 2017-03-22 中国人民大学 一种基于多通道喷嘴的多组分三维生物打印装置和方法
JP6861408B2 (ja) 2016-12-27 2021-04-21 東京応化工業株式会社 細胞培養用チップの製造方法
CN110891764B (zh) * 2017-03-15 2022-04-26 安斯百克特生物系统公司 用于打印纤维结构的系统和方法
CN106926456B (zh) * 2017-04-22 2018-12-28 广东工业大学 一种支架充液辅助成型系统
SG11201910173YA (en) * 2017-05-11 2019-11-28 Univ King Abdullah Sci & Tech Device and method for microfluidics-based 3d bioprinting
US11472839B2 (en) 2017-05-11 2022-10-18 King Abdullah University Of Science And Technology Peptide capable of forming a gel for use in tissue engineering and bioprinting
US12329820B2 (en) 2017-05-12 2025-06-17 Corning Incorporated Cross-linked shear thinning fluid with tunable rheology for 3D bioprinting and drug delivery
AU2018268713B2 (en) 2017-05-16 2024-04-18 Embody Inc. Biopolymer compositions, scaffolds and devices
CA3066421A1 (en) * 2017-06-06 2018-12-13 Organofab Technologies, Inc. Method and apparatus for a tissue engineering system
GB201710834D0 (en) 2017-07-05 2017-08-16 Univ Newcastle Printing apparatus and method
US12297416B2 (en) 2017-07-12 2025-05-13 Deka Products Limited Partneship System and method for transferring tissue
US10570362B2 (en) 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
FR3069806B1 (fr) * 2017-08-03 2019-08-23 Centre National De La Recherche Scientifique Tete d'impression d'une imprimante, imprimante et procede d'impression
JP7529567B2 (ja) 2017-10-24 2024-08-06 エムボディ インコーポレイテッド 生体高分子足場移植片およびその生成のための方法
US10967576B2 (en) 2017-11-10 2021-04-06 Local Motors IP, LLC Additive manufactured structure having a plurality of layers in a stacking direction and method for making the same
EP3720712A4 (en) 2017-12-08 2021-09-15 Inventia Life Science Pty Ltd. BIOPRINTER FOR THE PRODUCTION OF 3D CELL CONSTRUCTS
JP7420721B2 (ja) 2017-12-20 2024-01-23 アスペクト バイオシステムズ リミティド バイオ印刷された半月板インプラント及びその使用方法
US10350822B1 (en) * 2018-01-09 2019-07-16 Triastek Inc. Dosage forms with desired release profiles and methods of designing and making thereof
SE1850073A1 (en) * 2018-01-24 2019-07-25 Cellink Ab 3D bioprinters
CN110339469A (zh) * 2018-04-08 2019-10-18 上海叁钛生物科技有限公司 皮肤原位打印用打印头装置
CA3096488A1 (en) 2018-04-23 2019-10-31 Local Motors IP, LLC Method and apparatus for additive manufacturing
US11731342B2 (en) 2018-04-23 2023-08-22 Rapidflight Holdings, Llc Additively manufactured structure and method for making the same
DE102018111751A1 (de) * 2018-05-16 2019-11-21 Cellbricks Gmbh Verfahren zur Herstellung eines Zellkultureinsatzes mit mindestens einer Membran
GB201810447D0 (en) 2018-06-26 2018-08-08 Univ Leuven Kath Photopolymerised cell culture devices
US12186982B2 (en) * 2018-09-19 2025-01-07 Aspect Biosystems Ltd. Systems and methods for printing a core fiber
KR20210099013A (ko) * 2018-12-06 2021-08-11 인벤티아 라이프 사이언스 피티와이 엘티디 3d 바이오 프린터용 프린트 헤드 어셈블리
JP7686561B2 (ja) 2019-02-01 2025-06-02 エンボディ，インコーポレイテッド マイクロフルイディック押出
US11699272B2 (en) 2019-03-29 2023-07-11 Hewlett-Packard Development Company, L.P. Generating fluidic components
WO2020247313A1 (en) * 2019-06-01 2020-12-10 Northeastern University Microfluidic device for high-throughput screening of tumor cell adhesion and motility
WO2021029868A1 (en) * 2019-08-12 2021-02-18 Local Motors IP, LLC Additively manufactured structure and method for making the same
US11813790B2 (en) 2019-08-12 2023-11-14 Rapidflight Holdings, Llc Additively manufactured structure and method for making the same
US11083830B2 (en) 2019-10-14 2021-08-10 Fresenius Medical Care Holdings, Inc. Implantable fluid conduit
CN115087537B (zh) * 2019-11-01 2025-09-05 安斯百克特生物系统公司 用于打印芯壳纤维的系统和方法
KR102210626B1 (ko) * 2020-02-28 2021-02-02 (주)케이랩스 공기압을 이용한 3d 프린팅 장치
US20240327766A9 (en) * 2020-06-25 2024-10-03 Dloc Biosystems, Inc. Duct organoid-on-chip
AT523819B1 (de) * 2020-07-03 2021-12-15 Charlotte Ohonin Kultivierungsvorrichtung für ein Kulitivieren von Zellkulturen
US11673324B2 (en) 2020-08-20 2023-06-13 King Abdullah University Of Science And Technology Nozzle for 3D bioprinting
US12109327B2 (en) 2020-08-20 2024-10-08 King Abdullah University Of Science And Technology Scaffolds from self-assembling tetrapeptides support 3D spreading, osteogenic differentiation and angiogenesis of mesenchymal stem cells
WO2022038552A1 (en) * 2020-08-20 2022-02-24 King Adbullah University Of Science And Technology Nozzle for 3d bioprinting
US12116421B2 (en) 2020-09-02 2024-10-15 King Abdullah University Of Science And Technology Peptide-based Dopa containing adhesive gels
US20230382948A1 (en) * 2020-10-21 2023-11-30 King Abdullah University Of Science And Technology Delivery of endothelial cell-laden microgel elicits angiogenesis in self-assembling ultrashort peptide hydrogels
US11994520B2 (en) 2020-11-23 2024-05-28 King Abdullah University Of Science And Technology Developing lateral flow immunochromatography (LFIA) peptide-based test strips for rapid detection of antigens and antibodies against specific antigens
CN112549532A (zh) * 2020-12-08 2021-03-26 南通大学 一种基于3d打印装置的微流控芯片制备方法
WO2022134912A1 (zh) * 2020-12-25 2022-06-30 湖州艾先特电子科技有限公司 一种适用于3d生物打印机上料的搅拌机构
US11628600B2 (en) 2021-05-21 2023-04-18 Saudi Arabian Oil Company Fabrication method of transparent 3D polydimethylsiloxane devices with polycaprolactone molds
CN113500773B (zh) * 2021-07-08 2022-04-01 吉林大学 仿龙虾眼聚焦脉冲强光原位成型4d打印装置及方法
KR102742210B1 (ko) * 2021-08-31 2024-12-16 고려대학교 세종산학협력단 3차원 공압 액추에이터가 통합된 오리피스 가변형 마이크로 액적 생성기 및 그의 제조 방법
US20250058522A1 (en) * 2021-12-16 2025-02-20 Aspect Biosystems Ltd. Radial pump assembly and methods of using same
EP4558272A2 (en) * 2022-07-21 2025-05-28 ABS Global, Inc. Systems, methods, and apparatus for a microfluidic chip having a microchannel design which asymmetrically focuses particles
WO2025160474A1 (en) * 2024-01-25 2025-07-31 Carnegie Mellon University 3d bioprinted hydrogel microfluidic systems and perfusion bioreactors for engineering vascularized tissue constructs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080070304A1 (en) * 2004-02-24 2008-03-20 The Curators Of The Univeristy Of Missouri Self-Assembling Cell Aggregates and Methods of Making Engineered Tissue Using the Same
WO2012054195A2 (en) * 2010-10-21 2012-04-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
WO2013158508A1 (en) * 2012-04-20 2013-10-24 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing uv cross-linking

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292472A (en) 1992-12-18 1994-03-08 Bridgestone Corporation Coextrusion apparatus and method with rotating cord guidance
US7033603B2 (en) 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
US7051654B2 (en) * 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
CA2545941A1 (en) 2003-11-14 2005-06-23 Drexel University Method and apparatus for computer-aided tissue engineering for modeling, design and freeform fabrication of tissue scaffolds, constructs, and devices
WO2006020685A2 (en) 2004-08-11 2006-02-23 Cornell Research Foundation, Inc. Modular fabrication systems and methods
US9427496B2 (en) * 2005-02-18 2016-08-30 Drexel University Method for creating an internal transport system within tissue scaffolds using computer-aided tissue engineering
US8398935B2 (en) 2005-06-09 2013-03-19 The United States Of America, As Represented By The Secretary Of The Navy Sheath flow device and method
EP1790861A1 (en) 2005-11-25 2007-05-30 Bonsens AB Microfluidic system
JP2008017798A (ja) 2006-07-14 2008-01-31 Olympus Corp 生体組織製造装置および生体組織製造方法
US8047235B2 (en) * 2006-11-30 2011-11-01 Alcatel Lucent Fluid-permeable body having a superhydrophobic surface
US7771183B2 (en) * 2007-01-17 2010-08-10 3D Systems, Inc. Solid imaging system with removal of excess uncured build material
WO2009043052A1 (en) * 2007-09-27 2009-04-02 Columbia University Methods and systems for forming biocompatible materials
GB0722092D0 (en) 2007-11-09 2007-12-19 Q Chip Ltd Microfluidic device and method for producing sheathed flow
SG188832A1 (en) * 2008-02-29 2013-04-30 Agency Science Tech & Res Hydrodynamic spinning of polymer fiber in coaxial laminar flows
KR101004769B1 (ko) * 2008-09-09 2011-01-04 서울대학교산학협력단 광유체적 리소그래피 시스템 및 마이크로구조물 제조방법
EP2373782A1 (en) 2008-12-02 2011-10-12 Koninklijke Philips Electronics N.V. Coaxially encapsulated cell suspensions and microtissues
US20110136162A1 (en) 2009-08-31 2011-06-09 Drexel University Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers
JP5633077B2 (ja) 2009-10-14 2014-12-03 国立大学法人 東京大学 被覆されたマイクロゲルファイバ
CN107028886A (zh) 2009-11-04 2017-08-11 不列颠哥伦比亚大学 含有核酸的脂质粒子及相关的方法
WO2011082152A1 (en) * 2009-12-30 2011-07-07 Synthes Usa, Llc Intergrated multi-material implants and methods of manufacture
US9090868B2 (en) 2010-07-12 2015-07-28 President And Fellows Of Harvard College Alginate hydrogel fibers and related materials
US20120089238A1 (en) * 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
KR101222890B1 (ko) 2010-11-24 2013-01-17 고려대학교 산학협력단 표면 장력을 이용한 마이크로 밸브 및 이를 포함하는 미세유체칩, 및 이의 제조방법
AU2011340790A1 (en) 2010-12-06 2013-07-25 University Of South Australia High throughput microfluidic device
US9126366B2 (en) * 2011-06-15 2015-09-08 Korea Institute Of Machinery & Materials Apparatus and method for manufacturing cell culture scaffold
CN102309782B (zh) * 2011-09-02 2013-10-16 西安交通大学 一种基于活细胞的复杂三维微通道多孔支架的制备方法
US20140232035A1 (en) * 2013-02-19 2014-08-21 Hemant Bheda Reinforced fused-deposition modeling
US9579851B2 (en) * 2013-03-22 2017-02-28 Markforged, Inc. Apparatus for fiber reinforced additive manufacturing
FI3670155T3 (fi) 2013-06-13 2025-07-17 Aspect Biosystems Ltd Tulostuspää, järjestelmä kolmiulotteisten rakenteiden lisävalmistusta varten ja menetelmä siihen
WO2015066705A1 (en) 2013-11-04 2015-05-07 University Of Iowa Research Foundation Bioprinter and methods of using same
US20160297104A1 (en) * 2013-11-19 2016-10-13 Guill Tool & Engineering Coextruded, multilayer and multicomponent 3d printing inputs field

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080070304A1 (en) * 2004-02-24 2008-03-20 The Curators Of The Univeristy Of Missouri Self-Assembling Cell Aggregates and Methods of Making Engineered Tissue Using the Same
WO2012054195A2 (en) * 2010-10-21 2012-04-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
WO2013158508A1 (en) * 2012-04-20 2013-10-24 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing uv cross-linking

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