RU2642287C2 - Химерная частица hpv - Google Patents

Химерная частица hpv Download PDF

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RU2642287C2
RU2642287C2 RU2014126587A RU2014126587A RU2642287C2 RU 2642287 C2 RU2642287 C2 RU 2642287C2 RU 2014126587 A RU2014126587 A RU 2014126587A RU 2014126587 A RU2014126587 A RU 2014126587A RU 2642287 C2 RU2642287 C2 RU 2642287C2
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hpv
chimeric
polypeptide
seq
plant
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RU2014126587A
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Russian (ru)
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RU2014126587A (ru
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Эдвард Питер РЫБИЦКИ
Инга Изабель ХИТЦЕРОТ
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Юниверсити Оф Кейп Таун
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/295Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K14/01DNA viruses
    • C07K14/025Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • C12N7/045Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
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    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2710/00011Details
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    • C12N2710/20023Virus like particles [VLP]
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    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU2014126587A 2011-12-01 2012-12-03 Химерная частица hpv RU2642287C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA2011/08841 2011-12-01
ZA201108841 2011-12-01
PCT/IB2012/056912 WO2013080187A1 (en) 2011-12-01 2012-12-03 Hpv chimaeric particle

Publications (2)

Publication Number Publication Date
RU2014126587A RU2014126587A (ru) 2016-01-27
RU2642287C2 true RU2642287C2 (ru) 2018-01-24

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US (1) US9771397B2 (OSRAM)
EP (1) EP2785842A4 (OSRAM)
JP (1) JP6228922B2 (OSRAM)
KR (1) KR102013801B1 (OSRAM)
CN (1) CN103890177B (OSRAM)
AU (1) AU2012345443B2 (OSRAM)
BR (1) BR112014012491A2 (OSRAM)
CA (1) CA2850293C (OSRAM)
HK (1) HK1198703A1 (OSRAM)
IL (1) IL232584B (OSRAM)
IN (1) IN2014DN03054A (OSRAM)
MX (1) MX355352B (OSRAM)
MY (1) MY184076A (OSRAM)
PH (1) PH12014500466A1 (OSRAM)
RU (1) RU2642287C2 (OSRAM)
SG (1) SG11201401579UA (OSRAM)
WO (1) WO2013080187A1 (OSRAM)
ZA (1) ZA201403557B (OSRAM)

Cited By (1)

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RU2806424C2 (ru) * 2019-07-19 2023-10-31 Синоселлтех Лтд. Поливалентная иммуногенная композиция против папилломавируса человека

Families Citing this family (14)

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ES2845212T3 (es) 2009-04-13 2021-07-26 Inst Nat Sante Rech Med Partículas de HPV y usos de las mismas
WO2013119877A1 (en) 2012-02-07 2013-08-15 Aura Biosciences, Inc. Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
EP3046583B1 (en) * 2013-09-18 2019-02-13 Aura Biosciences, Inc. Virus-like particle conjugates for treatment of tumors
CN104531741B (zh) * 2014-08-22 2016-08-24 天津康希诺生物技术有限公司 增强hpv抗原表位肽免疫原性的方法及类病毒颗粒、颗粒制备方法与应用
CN105801704B (zh) * 2014-12-31 2020-06-02 艾托金生物医药(苏州)有限公司 一种具有抗宫颈癌细胞活性的重组疫苗构建方法及应用
CN108136039A (zh) 2015-08-18 2018-06-08 阿斯皮利安治疗学股份有限公司 用于光免疫疗法的组合物、联用及相关方法
CN114699525A (zh) 2015-08-18 2022-07-05 乐天医药生技股份有限公司 酞菁染料偶联物的制造方法及稳定偶联物
CN108473950A (zh) 2015-10-30 2018-08-31 美国政府卫生与公众服务部 靶向癌症治疗
BR112019020853A2 (pt) * 2017-04-04 2020-05-12 Avidea Technologies, Inc. Vacinas à base de peptídeo, métodos de fabricação e usos das mesmas para induzir uma resposta imune
CA3068012A1 (en) 2017-06-23 2018-12-27 Pathovax Llc Chimeric virus-like particles and uses thereof as antigen-specific redirectors of immune responses
AU2019414934A1 (en) 2018-12-27 2021-06-24 Verimmune Llc Conjugated virus-like particles and uses thereof as anti-tumor immune redirectors
WO2021161179A1 (en) * 2020-02-10 2021-08-19 University Of Cape Town Plant produced bovine papillomavirus virus-like particles and pseudovirions
AU2021364548A1 (en) 2020-10-19 2023-06-08 Verimmune Inc. Virus-inspired compositions and methods of redirecting preexisting immune responses using the same for treatment of cancer
KR102821363B1 (ko) 2023-02-06 2025-06-13 영산대학교산학협력단 드론에 장착된 라이다 센서를 기초로 하는 수심 측량 시스템

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US20020016372A1 (en) * 2000-07-31 2002-02-07 Allison Anthony Clifford Method for preventing and treating alzheimer's disease and brain damage associated with cardiov ascular disease and head injury
RU2206608C2 (ru) * 1994-05-16 2003-06-20 Мерк Энд Ко., Инк. Папилломавирусные вакцины
CA2486450A1 (en) * 2002-05-17 2003-11-27 University Of Cape Town Chimaeric human papillomavirus 16 l1 virus-like particles and method for preparing the particles
WO2010118424A2 (en) * 2009-04-10 2010-10-14 The Johns Hopkins University Papillomavirus-like particles (vlp) as broad spectrum human papillomavirus (hpv) vaccines
WO2010149752A2 (en) * 2009-06-25 2010-12-29 Glaxosmithline Biologicals S.A. Novel compositions

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IL141130A0 (en) 1998-08-14 2002-02-10 Merck & Co Inc Process for purifying human papilloma virus-like particles
US20040063188A1 (en) 2002-02-14 2004-04-01 Novavax, Inc. Kit for treating gastrointestinal tract
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CN102215861B (zh) 2009-06-19 2014-10-08 艾金株式会社 宫颈癌疫苗
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RU2206608C2 (ru) * 1994-05-16 2003-06-20 Мерк Энд Ко., Инк. Папилломавирусные вакцины
US20020016372A1 (en) * 2000-07-31 2002-02-07 Allison Anthony Clifford Method for preventing and treating alzheimer's disease and brain damage associated with cardiov ascular disease and head injury
CA2486450A1 (en) * 2002-05-17 2003-11-27 University Of Cape Town Chimaeric human papillomavirus 16 l1 virus-like particles and method for preparing the particles
WO2010118424A2 (en) * 2009-04-10 2010-10-14 The Johns Hopkins University Papillomavirus-like particles (vlp) as broad spectrum human papillomavirus (hpv) vaccines
WO2010149752A2 (en) * 2009-06-25 2010-12-29 Glaxosmithline Biologicals S.A. Novel compositions

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KIRNBAUER R. et al. Efficient Self-Assembly of Human Papillomavirus Type 16 LI and L1-L2 into Virus-Like Particles. JOURNAL OF VIROLOGY. 1993. V.67. No.12. P. 6929-6936. *
SCHELLENBACHER C. et al. Chimeric L1-L2 Virus-Like Particles as Potential Broad-Spectrum Human Papillomavirus Vaccines. JOURNAL OF VIROLOGY. 2009. V.83. No.19. P. 10085-10095;. *
VARSANI A. et al. Chimeric Human Papillomavirus Type 16 (HPV-16) L1 Particles Presenting the Common Neutralizing Epitope for the L2 Minor Capsid Protein of HPV-6 and HPV-16. JOURNAL OF VIROLOGY. 2003. V.77. No.15. P. 8386-8393;. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2806424C2 (ru) * 2019-07-19 2023-10-31 Синоселлтех Лтд. Поливалентная иммуногенная композиция против папилломавируса человека

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EP2785842A1 (en) 2014-10-08
HK1198703A1 (en) 2015-05-29
CA2850293C (en) 2019-10-08
AU2012345443B2 (en) 2017-10-26
KR102013801B1 (ko) 2019-08-23
MX2014006520A (es) 2014-11-21
RU2014126587A (ru) 2016-01-27
MY184076A (en) 2021-03-17
BR112014012491A2 (pt) 2017-06-06
EP2785842A4 (en) 2015-11-25
JP6228922B2 (ja) 2017-11-08
US9771397B2 (en) 2017-09-26
KR20140098061A (ko) 2014-08-07
NZ622595A (en) 2016-04-29
PH12014500466A1 (en) 2022-05-11
AU2012345443A1 (en) 2014-04-17
WO2013080187A1 (en) 2013-06-06
IL232584A0 (en) 2014-06-30
IN2014DN03054A (OSRAM) 2015-05-15
CN103890177A (zh) 2014-06-25
CA2850293A1 (en) 2013-06-06
SG11201401579UA (en) 2014-07-30
ZA201403557B (en) 2020-10-28
IL232584B (en) 2018-10-31
JP2015500229A (ja) 2015-01-05
MX355352B (es) 2018-04-17
CN103890177B (zh) 2016-03-09
US20140377367A1 (en) 2014-12-25

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