RU2598273C2 - Производные инсулина, содержащие дополнительные дисульфидные связи - Google Patents
Производные инсулина, содержащие дополнительные дисульфидные связи Download PDFInfo
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- RU2598273C2 RU2598273C2 RU2012157683/10A RU2012157683A RU2598273C2 RU 2598273 C2 RU2598273 C2 RU 2598273C2 RU 2012157683/10 A RU2012157683/10 A RU 2012157683/10A RU 2012157683 A RU2012157683 A RU 2012157683A RU 2598273 C2 RU2598273 C2 RU 2598273C2
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- human insulin
- insulin
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
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- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
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| PCT/EP2011/060383 WO2011161125A1 (en) | 2010-06-23 | 2011-06-21 | Insulin derivatives containing additional disulfide bonds |
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|---|---|---|---|---|
| RU2758367C2 (ru) * | 2016-12-16 | 2021-10-28 | Ново Нордиск А/С | Фармацевтические композиции, содержащие инсулин |
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| US9187547B2 (en) * | 2011-03-15 | 2015-11-17 | Novo Nordisk A/S | Human insulin analogues and derivatives comprising cysteine substitutions |
| CN104364262A (zh) * | 2011-12-21 | 2015-02-18 | 诺沃—诺迪斯克有限公司 | N末端修饰的胰岛素衍生物 |
| CN104364260B (zh) | 2012-04-11 | 2017-02-22 | 诺和诺德股份有限公司 | 胰岛素制剂 |
| US20150111820A1 (en) | 2012-07-09 | 2015-04-23 | Novo Nordisk A/S | Novel use of insulin derivatives |
| US9896496B2 (en) * | 2013-10-07 | 2018-02-20 | Novo Nordisk A/S | Derivative of an insulin analogue |
| AR099569A1 (es) * | 2014-02-28 | 2016-08-03 | Novo Nordisk As | Derivados de insulina y los usos médicos de estos |
| EP3250225A1 (en) * | 2015-01-29 | 2017-12-06 | Novo Nordisk A/S | Pharmaceutical composition for oral insulin administration comprising a tablet core and a polyvinyl alcohol coating |
| US11583572B2 (en) * | 2015-12-23 | 2023-02-21 | Case Western Reserve University | Encapsulation of ultra-stable insulin analogues with polymer melts |
| CN107436311B (zh) * | 2016-05-25 | 2021-11-19 | 正大天晴药业集团股份有限公司 | 一种鉴别胰岛素单体或胰岛素多聚体的方法 |
| KR102666154B1 (ko) | 2018-08-08 | 2024-05-20 | 주식회사 대웅제약 | 지속형 인슐린 아날로그 및 그 복합체 |
| CN113121649B (zh) * | 2019-12-26 | 2022-10-04 | 李瑛� | 一种新型两亲性蛋白、其制备方法及用途 |
| CN116789801B (zh) * | 2023-08-21 | 2023-11-14 | 南京赛诺生物技术有限公司 | 新型胰岛素衍生物及其用途 |
| WO2025104600A1 (en) * | 2023-11-15 | 2025-05-22 | Ambio, Inc. | Insulin analogs for the treatment of human metabolic disorder and disease |
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- 2011-06-21 KR KR1020137001441A patent/KR20130036290A/ko not_active Withdrawn
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2758367C2 (ru) * | 2016-12-16 | 2021-10-28 | Ново Нордиск А/С | Фармацевтические композиции, содержащие инсулин |
Also Published As
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|---|---|
| CA2802510A1 (en) | 2011-12-29 |
| EP2585485A1 (en) | 2013-05-01 |
| JP5931857B2 (ja) | 2016-06-08 |
| US8853155B2 (en) | 2014-10-07 |
| AU2011269000B2 (en) | 2015-04-23 |
| JP2013530974A (ja) | 2013-08-01 |
| US9512195B2 (en) | 2016-12-06 |
| US20140371140A1 (en) | 2014-12-18 |
| MX337549B (es) | 2016-03-10 |
| WO2011161125A1 (en) | 2011-12-29 |
| CN102985440B (zh) | 2016-10-26 |
| RU2012157683A (ru) | 2014-07-27 |
| BR112012033107A2 (pt) | 2016-10-11 |
| CN102985440A (zh) | 2013-03-20 |
| ZA201209345B (en) | 2013-08-28 |
| AU2011269000C1 (en) | 2015-10-08 |
| CN104693302A (zh) | 2015-06-10 |
| KR20130036290A (ko) | 2013-04-11 |
| AU2011269000A1 (en) | 2012-12-13 |
| US20130157938A1 (en) | 2013-06-20 |
| MX2012014641A (es) | 2013-02-07 |
| IL223288A0 (en) | 2013-02-03 |
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