RU2571284C2 - Фармацевтическая композиция и способ лечения гипертензии - Google Patents

Фармацевтическая композиция и способ лечения гипертензии Download PDF

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Publication number
RU2571284C2
RU2571284C2 RU2012151051/15A RU2012151051A RU2571284C2 RU 2571284 C2 RU2571284 C2 RU 2571284C2 RU 2012151051/15 A RU2012151051/15 A RU 2012151051/15A RU 2012151051 A RU2012151051 A RU 2012151051A RU 2571284 C2 RU2571284 C2 RU 2571284C2
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RU
Russia
Prior art keywords
amlodipine
dextromethorphan
hypertension
pharmaceutical composition
treatment
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RU2012151051/15A
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English (en)
Russian (ru)
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RU2012151051A (ru
Inventor
Чжао-Вэнь ЧЭНЬ
Си-Це ВАН
Синь-И ЧЖУАН
Original Assignee
Тсх Биофарм Корпорейшн, Лимитед
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2012151051/15A 2010-05-03 2011-04-29 Фармацевтическая композиция и способ лечения гипертензии RU2571284C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33054010P 2010-05-03 2010-05-03
US61/330,540 2010-05-03
PCT/CN2011/073560 WO2011137734A1 (en) 2010-05-03 2011-04-29 Pharmaceutical composition and method for treating hypertension

Publications (2)

Publication Number Publication Date
RU2012151051A RU2012151051A (ru) 2014-06-10
RU2571284C2 true RU2571284C2 (ru) 2015-12-20

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RU2012151051/15A RU2571284C2 (ru) 2010-05-03 2011-04-29 Фармацевтическая композиция и способ лечения гипертензии

Country Status (11)

Country Link
US (2) US20130053411A1 (https=)
EP (1) EP2566478A4 (https=)
JP (1) JP5847162B2 (https=)
KR (1) KR20130061148A (https=)
CN (1) CN102869360B (https=)
AU (1) AU2011250485B2 (https=)
BR (1) BR112012028153A2 (https=)
MY (1) MY161853A (https=)
RU (1) RU2571284C2 (https=)
TW (1) TWI583383B (https=)
WO (1) WO2011137734A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11491160B2 (en) 2016-12-14 2022-11-08 Respira Therapeutics, Inc. Methods and compositions for treatment of pulmonary hypertension and other lung disorders
US11806314B2 (en) 2013-12-09 2023-11-07 Respira Therapeutics, Inc. PDE5 inhibitor powder formulations and methods relating thereto

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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US9102635B2 (en) * 2013-02-14 2015-08-11 Novartis Ag Substituted bisphenyl butanoic acid derivatives as NEP inhibitors with improved in vivo efficacy
WO2017028814A1 (en) * 2015-08-20 2017-02-23 Tsh Biopharm Corporation Ltd. Pharmaceutical composition comprising amlodipine and dextromethorphan
KR20240096848A (ko) 2017-01-25 2024-06-26 더 조지 인스티튜트 포 글로벌 헬스 고혈압의 치료를 위한 조성물
US12521380B2 (en) 2017-01-25 2026-01-13 The George Institute for Global Health Compositions for the treatment of hypertension

Citations (3)

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RU2005104418A (ru) * 2002-07-17 2005-10-27 Аванир Фармасьютикалс (Us) Фармацевтические композиции для лечения неврологических расстройств, содержащие декстрометорфан и квинидин
WO2007097765A1 (en) * 2006-02-24 2007-08-30 Blue Blood Biotech Corp. Methods and compositions for bactericide, bacteriostatic and anti-inflammation
RU2322262C2 (ru) * 2002-12-18 2008-04-20 Уайт Композиции нестероидных противовоспалительных лекарственных средств, противозастойных средств и антигистаминов

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RU2005104418A (ru) * 2002-07-17 2005-10-27 Аванир Фармасьютикалс (Us) Фармацевтические композиции для лечения неврологических расстройств, содержащие декстрометорфан и квинидин
RU2322262C2 (ru) * 2002-12-18 2008-04-20 Уайт Композиции нестероидных противовоспалительных лекарственных средств, противозастойных средств и антигистаминов
WO2007097765A1 (en) * 2006-02-24 2007-08-30 Blue Blood Biotech Corp. Methods and compositions for bactericide, bacteriostatic and anti-inflammation

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ШТРЫГОЛЬ С.Ю. "Блокаторы кальциевых каналов в кардиологии". Провизор, 2004, вып.6, найдено из Интернет:http://www.provisor.com.ua/archive/2004/#6/art_12.php. GOJANOVIC B et al. "Concomitant calcium entry blockade and inhibition of the rennin-angiotensin system: a rational and effective means for treating hypertendion". Journal of the Renin-Angiotensin-Aldosterone System, 2008, 9(1):1-9, doi:10:10.3317/jraas.2008.007. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11806314B2 (en) 2013-12-09 2023-11-07 Respira Therapeutics, Inc. PDE5 inhibitor powder formulations and methods relating thereto
US11491160B2 (en) 2016-12-14 2022-11-08 Respira Therapeutics, Inc. Methods and compositions for treatment of pulmonary hypertension and other lung disorders
US11491161B2 (en) 2016-12-14 2022-11-08 Respira Therapeutics, Inc. Methods and compositions for treatment of pulmonary hypertension and other lung disorders
US12263174B2 (en) 2016-12-14 2025-04-01 Respira Therapeutics, Inc. Methods and compositions for treatment of pulmonary hypertension and other lung disorders

Also Published As

Publication number Publication date
KR20130061148A (ko) 2013-06-10
TW201206437A (en) 2012-02-16
US20130053411A1 (en) 2013-02-28
CN102869360B (zh) 2015-03-25
EP2566478A1 (en) 2013-03-13
JP5847162B2 (ja) 2016-01-20
US9744165B2 (en) 2017-08-29
MY161853A (en) 2017-05-15
AU2011250485B2 (en) 2016-07-07
AU2011250485A1 (en) 2012-12-06
EP2566478A4 (en) 2014-04-30
BR112012028153A2 (pt) 2018-08-07
CN102869360A (zh) 2013-01-09
WO2011137734A1 (en) 2011-11-10
TWI583383B (zh) 2017-05-21
RU2012151051A (ru) 2014-06-10
US20160235741A1 (en) 2016-08-18
JP2013525460A (ja) 2013-06-20

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Effective date: 20200430