RU2543348C2 - Способ лечения путем применения комбинированной терапии - Google Patents
Способ лечения путем применения комбинированной терапии Download PDFInfo
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- RU2543348C2 RU2543348C2 RU2011142750/15A RU2011142750A RU2543348C2 RU 2543348 C2 RU2543348 C2 RU 2543348C2 RU 2011142750/15 A RU2011142750/15 A RU 2011142750/15A RU 2011142750 A RU2011142750 A RU 2011142750A RU 2543348 C2 RU2543348 C2 RU 2543348C2
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| WO2010111172A1 (en) * | 2009-03-23 | 2010-09-30 | Ambit Biosciences Corporation | Methods of treatment using combination therapy |
| SMT202000092T1 (it) | 2009-05-14 | 2020-05-08 | Ambit Biosciences Corp | Formulazione essiccata a spruzzo o liofilizzata di ac220 |
| US9358233B2 (en) | 2010-11-29 | 2016-06-07 | Boehringer Ingelheim International Gmbh | Method for treating acute myeloid leukemia |
| US9370535B2 (en) | 2011-05-17 | 2016-06-21 | Boehringer Ingelheim International Gmbh | Method for treatment of advanced solid tumors |
| AU2012321106C1 (en) * | 2011-11-03 | 2016-11-24 | Takeda Pharmaceutical Company Limited | Administration of NEDD8-activating enzyme inhibitor and hypomethylating agent |
| CN103172648B (zh) * | 2011-12-20 | 2016-05-25 | 上海迪诺医药科技有限公司 | 三杂环衍生物、制备方法及应用 |
| JP6116847B2 (ja) | 2012-10-01 | 2017-04-19 | アムビト バイオサイエンシス コーポレーションＡｍｂｉｔ Ｂｉｏｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ | シクロデキストリンとの混合体を含有する錠剤 |
| EP2928456B1 (en) * | 2012-12-07 | 2021-02-03 | Onconova Therapeutics, Inc. | Treatment of hematological cancer refractory to an anti-cancer agent |
| US20150031699A1 (en) | 2013-07-26 | 2015-01-29 | Boehringer Ingelheim International Gmbh | Treatment of myelodysplastic syndrome |
| JP6529138B2 (ja) * | 2013-09-13 | 2019-06-12 | ウェスタン ユニバーシティ オブ ヘルス サイエンス | 化学療法耐性を克服するためのウィルホルリドａの使用 |
| US9867831B2 (en) | 2014-10-01 | 2018-01-16 | Boehringer Ingelheim International Gmbh | Combination treatment of acute myeloid leukemia and myelodysplastic syndrome |
| EP3260119B1 (en) * | 2015-02-20 | 2023-11-15 | Daiichi Sankyo Company, Limited | Combination method for treating cancer |
| WO2017010382A1 (ja) * | 2015-07-14 | 2017-01-19 | 国立大学法人大阪大学 | 筋強直性ジストロフィー治療薬 |
| CN116196426A (zh) | 2015-07-16 | 2023-06-02 | 百欧肯治疗有限公司 | 治疗癌症的组合物及方法 |
| CA3014530A1 (en) | 2016-02-23 | 2017-08-31 | Biolinerx Ltd. | Methods of treating acute myeloid leukemia |
| JP6856657B2 (ja) * | 2016-02-26 | 2021-04-07 | アジオス ファーマシューティカルズ， インコーポレイテッド | 血液学的悪性疾患および固形腫瘍の処置のためのｉｄｈ１阻害剤 |
| JP7082263B2 (ja) | 2016-03-15 | 2022-06-08 | オリソン ヘノミクス エセ． アー． | 造血器悪性腫瘍の治療のための、ｌｓｄ１阻害剤の組合せ |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| US20210292410A1 (en) | 2017-12-07 | 2021-09-23 | Morphosys Ag | Treatment paradigm for an anti-cd19 antibody and venetoclax combination treatment |
| KR101954370B1 (ko) | 2018-07-25 | 2019-03-05 | 한미약품 주식회사 | 피리미딘 화합물 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 |
| WO2020171646A1 (ko) | 2019-02-22 | 2020-08-27 | 한미약품 주식회사 | Flt3 저해제 및 저메틸화제를 포함하는 급성 골수성 백혈병의 치료를 위한 약학적 조성물 |
| TW202045174A (zh) | 2019-02-28 | 2020-12-16 | 日商富士軟片股份有限公司 | 組合醫藥 |
| JP2022538817A (ja) * | 2019-06-27 | 2022-09-06 | ハンミ ファーマシューティカル カンパニー リミテッド | Ｆｌｔ３阻害剤および化学療法剤を含む急性骨髄白血病を治療するための薬学的組成物 |
| KR102694140B1 (ko) * | 2020-12-31 | 2024-08-12 | 울산대학교 산학협력단 | 소라페닙의 간암에 대한 활성 증진용 조성물 |
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| EP0816366A1 (en) * | 1995-03-13 | 1998-01-07 | Nikken Chemicals Company, Limited | Imidazothiazole compounds |
| WO2007109120A2 (en) * | 2006-03-17 | 2007-09-27 | Ambit Biosciences Corporation | Imidazolothiazole compounds for the treatment of disease |
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| GB1050899A (enExample) | 1963-12-22 | |||
| DE2012888C3 (de) | 1970-03-14 | 1981-04-02 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden |
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| US4328245A (en) | 1981-02-13 | 1982-05-04 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4409239A (en) | 1982-01-21 | 1983-10-11 | Syntex (U.S.A.) Inc. | Propylene glycol diester solutions of PGE-type compounds |
| US4751221A (en) | 1985-10-18 | 1988-06-14 | Sloan-Kettering Institute For Cancer Research | 2-fluoro-arabinofuranosyl purine nucleosides |
| US5033252A (en) | 1987-12-23 | 1991-07-23 | Entravision, Inc. | Method of packaging and sterilizing a pharmaceutical product |
| US5052558A (en) | 1987-12-23 | 1991-10-01 | Entravision, Inc. | Packaged pharmaceutical product |
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| US5323907A (en) | 1992-06-23 | 1994-06-28 | Multi-Comp, Inc. | Child resistant package assembly for dispensing pharmaceutical medications |
| WO2002076439A2 (en) * | 2001-03-23 | 2002-10-03 | The Board Of Trustees Of The University Of Illinois | Compounds capable of modulating the activity of multidrug transporters and therapeutic use of the same |
| EP1412369B1 (en) | 2001-08-02 | 2008-05-07 | Ilex Oncology, Inc. | Process for preparing purine nucleosides |
| US6887855B2 (en) | 2003-03-17 | 2005-05-03 | Pharmion Corporation | Forms of 5-azacytidine |
| US7038038B2 (en) | 2003-03-17 | 2006-05-02 | Pharmion Corporation | Synthesis of 5-azacytidine |
| US7192781B2 (en) | 2004-04-13 | 2007-03-20 | Pharmion Corporation | Methods for stabilizing 5-azacytidine in plasma |
| US20070006613A1 (en) | 2005-06-20 | 2007-01-11 | Hirsch Victoria H | Coil beaded fashion accessory with attached key ring |
| WO2008028193A2 (en) | 2006-09-01 | 2008-03-06 | Pharmion Corporation | Colon-targeted oral formulations of cytidine analogs |
| CN101868465B (zh) | 2007-09-19 | 2013-12-25 | 埃姆比特生物科学公司 | 包含N-(5-叔丁基-异噁唑-3-基)-N’-{4-[7-(2-吗啉-4-基-乙氧基)咪唑并[2，1-b][1，3]苯并噻唑-2-基]苯基}脲的固体形式、其组合物及其应用 |
| AU2008325141B2 (en) | 2007-11-08 | 2014-03-20 | Ambit Biosciences Corp. | Methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea to treat proliferative disease |
| WO2010054058A1 (en) | 2008-11-06 | 2010-05-14 | Ambit Bioscience Corporation | Imidazolothiazole compounds as modulators of protein kinase |
| WO2010111172A1 (en) * | 2009-03-23 | 2010-09-30 | Ambit Biosciences Corporation | Methods of treatment using combination therapy |
| SMT202000092T1 (it) | 2009-05-14 | 2020-05-08 | Ambit Biosciences Corp | Formulazione essiccata a spruzzo o liofilizzata di ac220 |
| CN102639539B (zh) | 2009-11-05 | 2014-12-10 | 埃姆比特生物科学公司 | 用于制备咪唑并[2，1-b][1，3]苯并噻唑衍生物的方法 |
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| EP0816366A1 (en) * | 1995-03-13 | 1998-01-07 | Nikken Chemicals Company, Limited | Imidazothiazole compounds |
| WO2007109120A2 (en) * | 2006-03-17 | 2007-09-27 | Ambit Biosciences Corporation | Imidazolothiazole compounds for the treatment of disease |
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| WO2010111172A1 (en) | 2010-09-30 |
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| US8357690B2 (en) | 2013-01-22 |
| EP2410987B1 (en) | 2018-05-16 |
| FR24C1013I1 (fr) | 2024-05-24 |
| KR101755725B1 (ko) | 2017-07-07 |
| RU2011142750A (ru) | 2013-04-27 |
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| ZA201106730B (en) | 2012-11-28 |
| IL215131A (en) | 2015-08-31 |
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| CN102438588B (zh) | 2015-04-01 |
| JP2012521435A (ja) | 2012-09-13 |
| AU2010228982B2 (en) | 2015-05-14 |
| US20100292177A1 (en) | 2010-11-18 |
| JP6033678B2 (ja) | 2016-11-30 |
| NZ595382A (en) | 2014-02-28 |
| FR24C1013I2 (fr) | 2025-03-28 |
| AU2010228982A1 (en) | 2011-10-20 |
| KR20120000567A (ko) | 2012-01-02 |
| CN102438588A (zh) | 2012-05-02 |
| ES2681529T3 (es) | 2018-09-13 |
| US8836218B2 (en) | 2014-09-16 |
| US20130137650A1 (en) | 2013-05-30 |
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