RU2542500C2 - Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1) - Google Patents

Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1) Download PDF

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Publication number
RU2542500C2
RU2542500C2 RU2010137392/15A RU2010137392A RU2542500C2 RU 2542500 C2 RU2542500 C2 RU 2542500C2 RU 2010137392/15 A RU2010137392/15 A RU 2010137392/15A RU 2010137392 A RU2010137392 A RU 2010137392A RU 2542500 C2 RU2542500 C2 RU 2542500C2
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Russia
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glp
fdkp
diketopiperazine
dose
peptide
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RU2010137392/15A
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English (en)
Russian (ru)
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RU2010137392A (ru
Inventor
Стефани ГРИН
Дэвид БРАНДТ
Кохава ГЕЛЬБЕР
Марк КИНГ
Вэйман Вэнделл ЧИЗАМ
Кит ОБЕРГ
Андреа ЛЕОНЕ-БЭЙ
Марк Дж. ХОУКЕНСОН
Мэри Фейрис
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Маннкайнд Корпорейшн
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
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RU2010137392/15A 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1) RU2542500C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74488206P 2006-04-14 2006-04-14
US60/744,882 2006-04-14

Related Parent Applications (1)

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RU2008144965/15A Division RU2409349C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1)

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RU2010137392A RU2010137392A (ru) 2012-03-20
RU2542500C2 true RU2542500C2 (ru) 2015-02-20

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RU2010137392/15A RU2542500C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)
RU2008144965/15A RU2409349C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1)
RU2014152320A RU2014152320A (ru) 2006-04-14 2014-12-23 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)

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RU2008144965/15A RU2409349C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1)
RU2014152320A RU2014152320A (ru) 2006-04-14 2014-12-23 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)

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Country Link
EP (1) EP2010155A2 (cg-RX-API-DMAC7.html)
JP (3) JP5415938B2 (cg-RX-API-DMAC7.html)
KR (3) KR20150042304A (cg-RX-API-DMAC7.html)
CN (2) CN104288756A (cg-RX-API-DMAC7.html)
AU (1) AU2007238000B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0709964A2 (cg-RX-API-DMAC7.html)
CA (1) CA2646400A1 (cg-RX-API-DMAC7.html)
HK (1) HK1206241A1 (cg-RX-API-DMAC7.html)
MX (1) MX2008013216A (cg-RX-API-DMAC7.html)
RU (3) RU2542500C2 (cg-RX-API-DMAC7.html)
WO (1) WO2007121411A2 (cg-RX-API-DMAC7.html)

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