RU2472539C2 - Способы и устройства для доставки препарата десмопрессина - Google Patents

Способы и устройства для доставки препарата десмопрессина Download PDF

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Publication number
RU2472539C2
RU2472539C2 RU2010108304/14A RU2010108304A RU2472539C2 RU 2472539 C2 RU2472539 C2 RU 2472539C2 RU 2010108304/14 A RU2010108304/14 A RU 2010108304/14A RU 2010108304 A RU2010108304 A RU 2010108304A RU 2472539 C2 RU2472539 C2 RU 2472539C2
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RU
Russia
Prior art keywords
desmopressin
patient
skin
flow rate
concentration
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RU2010108304/14A
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English (en)
Russian (ru)
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RU2010108304A (ru
Inventor
Самьюэл ХЕРШКОВИТЦ
Сеймор Файн
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Аллерган, Инк.
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Publication of RU2010108304A publication Critical patent/RU2010108304A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/482—Varying injection pressure, e.g. by varying speed of injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
RU2010108304/14A 2007-08-06 2008-08-06 Способы и устройства для доставки препарата десмопрессина RU2472539C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95415907P 2007-08-06 2007-08-06
US60/954,159 2007-08-06
PCT/US2008/072290 WO2009021007A1 (en) 2007-08-06 2008-08-06 Methods and devices for desmopressin drug delivery

Publications (2)

Publication Number Publication Date
RU2010108304A RU2010108304A (ru) 2011-09-20
RU2472539C2 true RU2472539C2 (ru) 2013-01-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2010108304/14A RU2472539C2 (ru) 2007-08-06 2008-08-06 Способы и устройства для доставки препарата десмопрессина

Country Status (10)

Country Link
US (3) US8399410B2 (cg-RX-API-DMAC7.html)
EP (1) EP2197532A1 (cg-RX-API-DMAC7.html)
JP (3) JP5451613B2 (cg-RX-API-DMAC7.html)
KR (2) KR20140143461A (cg-RX-API-DMAC7.html)
CN (1) CN101801452B (cg-RX-API-DMAC7.html)
AU (1) AU2008283929B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0814986A2 (cg-RX-API-DMAC7.html)
CA (2) CA2988753A1 (cg-RX-API-DMAC7.html)
RU (1) RU2472539C2 (cg-RX-API-DMAC7.html)
WO (1) WO2009021007A1 (cg-RX-API-DMAC7.html)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6445933A (en) * 1987-08-12 1989-02-20 Nissan Motor Control device in internal combustion engine with automatic gear
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
WO2008079440A2 (en) 2006-07-10 2008-07-03 Medipacs, Inc. Super elastic epoxy hydrogel
CA2988753A1 (en) 2007-08-06 2009-02-12 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
WO2009073734A2 (en) 2007-12-03 2009-06-11 Medipacs, Inc. Fluid metering device
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
LT3085381T (lt) 2008-05-21 2018-06-11 Ferring B.V. Burnoje disperguojamas desmopresinas, skirtas naktinio šlapinimosi netrikdomo miego periodo pailginimui
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
PT4104848T (pt) 2009-06-18 2024-01-04 Acerus Pharmaceuticals Usa Llc Administração segura de desmopressina
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172645A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
US20110172637A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
RU2014102493A (ru) 2011-06-29 2015-08-10 Аллерган, Инк. Алкафтадин для применения при лечении уртикарии
US9474685B2 (en) * 2011-09-28 2016-10-25 Sure-Shot Medical Device Inc. Apparatus for localized dermatological treatment
US10278925B2 (en) 2012-01-04 2019-05-07 Wellesley Pharmaceuticals, Llc Delayed-release formulations, methods of making and use thereof
JP2015506359A (ja) 2012-01-04 2015-03-02 ウェルズリー ファーマスーティカルズ、エルエルシー 排尿頻度を減少させるための遅延放出製剤およびその使用の方法
JP6277953B2 (ja) * 2012-02-29 2018-02-14 凸版印刷株式会社 針状体の製造方法
HK1206374A1 (en) 2012-03-14 2016-01-08 麦德医像公司 Smart polymer materials with excess reactive molecules
CA2879640A1 (en) * 2012-07-27 2014-01-03 Wellesley Pharmaceuticals, Llc Pharmaceutical formulation for reducing frequency of urination and method of use thereof
AU2014222308B2 (en) * 2013-02-28 2018-11-08 Vivasor, Inc. Transdermal drug delivery device
JP2016525147A (ja) 2013-07-23 2016-08-22 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ ５−α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物
CN105579057A (zh) 2013-07-23 2016-05-11 阿勒根公司 包含与β-3-肾上腺素能受体激动剂组合的去氨加压素的方法和组合物
WO2016006409A1 (ja) * 2014-07-09 2016-01-14 凸版印刷株式会社 液剤注入装置
WO2016039418A1 (ja) * 2014-09-11 2016-03-17 久光製薬株式会社 マイクロニードルデバイス
KR20170097045A (ko) * 2014-11-20 2017-08-25 알레간 인코포레이티드 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물
KR101708767B1 (ko) 2016-09-07 2017-02-21 주식회사 파마리서치프로덕트 인공피부용 약물충전장치
CN110300612B (zh) 2016-12-16 2022-04-22 索伦托治疗有限公司 具有控制器组件的流体递送装置及其使用方法
USD836774S1 (en) 2016-12-16 2018-12-25 Sorrento Therapeutics, Inc. Cartridge for a fluid delivery apparatus
USD819197S1 (en) 2016-12-16 2018-05-29 Kimberly-Clark Worldwide, Inc. Fluid delivery apparatus
CN116271481A (zh) 2016-12-16 2023-06-23 索伦托治疗有限公司 用于给予适合治疗偏头痛或丛集性头痛的药物的方法
JP6977258B2 (ja) * 2016-12-20 2021-12-08 株式会社リコー 中空構造体
KR101858394B1 (ko) * 2017-03-31 2018-05-15 부산대학교 산학협력단 경피형 약물 전달 패치, 경피형 약물 전달 시스템 및 약물 투여량을 모니터링하는 방법
JP6884037B2 (ja) * 2017-05-29 2021-06-09 株式会社ジェイメック パルス電圧治療装置
CN107260245A (zh) * 2017-07-08 2017-10-20 徐欣欣 一种凝血功能障碍患者的紧急辅助止血装置
JP7291632B2 (ja) * 2017-12-21 2023-06-15 杏林製薬株式会社 夜間頻尿治療剤
KR101891465B1 (ko) * 2018-03-16 2018-08-23 부산대학교 산학협력단 경피형 약물 전달 패치, 경피형 약물 전달 시스템 및 약물 투여량을 모니터링하는 방법
CN108939284B (zh) * 2018-08-16 2023-08-08 厦门薇针医药科技有限公司 可溶解微针注射装置
DE102019105694A1 (de) * 2019-03-06 2020-09-10 Lts Lohmann Therapie-Systeme Ag Mikronadelarray aufweisend ein wärmeerzeugendes Element
CN111939454A (zh) * 2019-05-16 2020-11-17 (株)我丽美业有限公司 一种用于诱导药物吸收的皮肤刺激仪
US20230321419A1 (en) * 2020-01-10 2023-10-12 The Regents Of The University Of California Gelatin-based microneedle patch for minimally-invasive extraction of bodily fluids
KR102720559B1 (ko) * 2023-04-04 2024-10-24 (주)이지템 에너지 기반 디바이스

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0278474A1 (en) * 1987-02-10 1988-08-17 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
US5848991A (en) * 1990-12-13 1998-12-15 Elan Medical Technologies Limited Athlone, Co. Intradermal drug delivery device and method for intradermal delivery of drugs
US20020016562A1 (en) * 1996-06-18 2002-02-07 Michel J. N. Cormier Device and method for enhancing transdermal flux of agents being delivered or sampled
WO2004041153A2 (en) * 2002-05-07 2004-05-21 Fein Seymour H Pharmaceutical composition including low dosages of desmopressin
WO2005041871A2 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin
RU2282468C2 (ru) * 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3989816A (en) 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4316893A (en) 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4405616A (en) 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4285858A (en) 1979-10-30 1981-08-25 Mt. Sinai School Of Medicine Of The City University Of N.Y. Vasopressin analogs
US4263283A (en) 1980-05-16 1981-04-21 Ferring Pharmaceuticals, Inc. Method for prophylaxis and/or treatment of sickle cell disease
US4557934A (en) 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
SE8306367L (sv) 1983-11-18 1985-05-19 Ferring Ab Antidiuretiskt verkande farmaceutiskt preparat
US4863737A (en) 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US4588580B2 (en) 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US4698062A (en) * 1985-10-30 1987-10-06 Alza Corporation Medical device for pulsatile transdermal delivery of biologically active agents
IE60941B1 (en) 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US5032109A (en) * 1987-02-10 1991-07-16 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US4783450A (en) 1987-04-13 1988-11-08 Warner-Lambert Company Use of commercial lecithin as skin penetration enhancer
US5091186A (en) 1989-08-15 1992-02-25 Cygnus Therapeutic Systems Biphasic transdermal drug delivery device
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
SE9101022D0 (sv) 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US6746678B1 (en) 1991-02-22 2004-06-08 Howard K. Shapiro Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments
US5464387A (en) 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
US5298256A (en) 1992-04-28 1994-03-29 Corint, Ltd. Desmopressin buccal patch composition
US5534496A (en) 1992-07-07 1996-07-09 University Of Southern California Methods and compositions to enhance epithelial drug transport
CA2090738C (en) 1993-02-24 1996-05-21 Hema-Quebec Use of paf
SE9300937L (sv) 1993-03-19 1994-09-20 Anne Fjellestad Paulsen Komposition för oral administrering av peptider
SE501677C2 (sv) 1993-06-18 1995-04-10 Ferring Bv Biologiskt aktiva vasopressinanaloger, farmaceutiska preparat innehållande dem samt deras användning för framställning av läkemedel
ES2149880T3 (es) 1993-06-29 2000-11-16 Ferring Bv Sintesis de peptidos ciclicos.
US5482931A (en) 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
ES2158898T3 (es) 1993-06-29 2001-09-16 Ferring Bv Composiciones para la administracion de desmopresina por via nasal.
US5674850A (en) 1993-12-23 1997-10-07 Ferring Ab High purity desmopressin produced in large single batches
US5985835A (en) 1993-12-23 1999-11-16 Ferring B.V. Desmopressin for nocturia, incontinence and enuresis
US5500413A (en) 1993-06-29 1996-03-19 Ferring Ab Process for manufacture of 1-deamino-8-D-arginine vasopressin
WO1995014037A1 (en) 1993-11-17 1995-05-26 Ibah, Inc. Transparent liquid for encapsulated drug delivery
SE9400918L (sv) 1994-03-18 1995-09-19 Anne Fjellstad Paulsen Stabiliserad komposition för oral administrering av peptider
JP2551742B2 (ja) 1994-05-23 1996-11-06 三星電機株式会社 医薬品投与用皮膚傷形成装置
KR0134152B1 (ko) 1994-05-23 1998-04-14 이형도 의약품 투여용 피부흠집 형성장치
GB9410388D0 (en) 1994-05-24 1994-07-13 Erba Carlo Spa Method for the preparation of 9-amino camptothecin
SE518619C2 (sv) 1994-12-09 2002-10-29 Gs Dev Ab Komposition för reglerad frisättning innehållande monokaproin
GB9502879D0 (en) 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
IL113459A (en) 1995-04-23 2000-07-16 Electromagnetic Bracing System Electrophoretic cuff apparatus
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
US5843016A (en) 1996-03-18 1998-12-01 Physion S.R.L. Electromotive drug administration for treatment of acute urinary outflow obstruction
TW411277B (en) 1996-05-13 2000-11-11 Hisamitsu Pharmaceutical Co Percutaneous tape preparation containing fentanyl
US5763398A (en) 1996-06-20 1998-06-09 Ferring B.V. Nasal administration of desmopressin
US5922680A (en) 1996-10-23 1999-07-13 Ferring, B.V. Stabilized composition for oral administration of peptides
SE9604341D0 (sv) 1996-11-26 1996-11-26 Ferring Bv Hepta-peptide oxytocin analogue
FR2758195B1 (fr) 1997-01-09 1999-02-26 Sgs Thomson Microelectronics Coprocesseur d'arithmetique modulaire comprenant deux circuits de multiplication operant en parallele
US5985385A (en) 1997-05-23 1999-11-16 No Fire Technologies, Inc. Fire and heat protection wrap for conduits, cable trays, other electrical transmission lines and gas and oil pipelines
US6511974B1 (en) 1997-07-30 2003-01-28 Wyeth Tricyclic vasopressin agonists
US5932745A (en) 1997-07-30 1999-08-03 American Home Products Corporation Process for converting propargylic amine-N-oxides to enaminones
US6194407B1 (en) 1997-07-30 2001-02-27 American Home Products Corporation Tricyclic pyrido vasopressin agonists
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US7153845B2 (en) 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US20040018241A1 (en) 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
US6322532B1 (en) 1998-06-24 2001-11-27 3M Innovative Properties Company Sonophoresis method and apparatus
US6090803A (en) 1998-07-24 2000-07-18 American Home Products Corporation Tricyclic vasopressin agonists
US7138393B2 (en) 1998-07-24 2006-11-21 Wyeth Biologically active vasopressin agonist metabolites
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
US20060025387A1 (en) 1998-12-23 2006-02-02 Cytoscan Sciences Llc Compositions and methods for the treatment of disorders of the central and peripheral nervous systems
US6297234B1 (en) 1999-02-04 2001-10-02 American Home Products Corporation Arylthiophene vasopressin agonists
US6620807B1 (en) 1999-02-04 2003-09-16 Wyeth Pyridobenzodiazepine and pyridobenzoxazepine carboxyamide vasopressin agonists
US6344451B1 (en) 1999-02-04 2002-02-05 American Home Products Pyrrolobenzodiazepine carboxyamide vasopressin agonists
US6235900B1 (en) 1999-02-04 2001-05-22 American Home Products Corporation Tricyclic pyridine N-oxides vasopressin agonists
US6314317B1 (en) 1999-02-18 2001-11-06 Biovalve Technologies, Inc. Electroactive pore
AR014640A1 (es) 1999-02-23 2001-03-28 Univ Nac Quilmes UNA COMPOSICíoN FARMACÉUTICA INHIBIDORA DE LA DISEMINACIoN METASTÁSICA DURANTE LA CIRUGíA DE UN TUMOR CANCEROSO, UN PROCEDIMENTO DE PREPARACIoN Y UN KIT PARA UNA FORMULACIoN INYECTABLE.
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US7060708B2 (en) 1999-03-10 2006-06-13 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients
GB2355454A (en) 1999-10-20 2001-04-25 Ferring Bv Antidiuretic agents
US6558695B2 (en) 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
GB0000079D0 (en) 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
ATE501751T1 (de) 2000-01-07 2011-04-15 Valeritas Inc Injektionsvorrichtung
US20070032410A1 (en) 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
AT409081B (de) 2000-02-16 2002-05-27 Gebro Pharma Gmbh Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung
GB0015601D0 (en) 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
TWI287984B (en) 2000-10-17 2007-10-11 Wyeth Corp Pharmaceutical composition for modulating bladder function
WO2002051470A2 (en) 2000-11-30 2002-07-04 Biovalve Technologies, Inc. Injection systems
ES2717656T3 (es) 2000-11-30 2019-06-24 Valeritas Inc Dispositivo con microsonda amovible sustancialmente libre sobre el alojamiento
WO2002064193A2 (en) 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
US7027478B2 (en) 2000-12-21 2006-04-11 Biovalve Technologies, Inc. Microneedle array systems
JP5354763B2 (ja) 2001-03-16 2013-11-27 アルザ・コーポレーシヨン フェンタニルを投与するための経皮的張り付け剤
DK1381608T3 (da) 2001-04-12 2008-02-04 Wyeth Corp Cyclohexylphenylvasopressinagonister
EP1381370B1 (en) 2001-04-12 2007-03-07 Wyeth N-biphenylcarbonyl- and n-phenylpyridylcarbonyl substituted bi- and tricyclic azepines and diazepines as vasopressing agonists
US7022699B2 (en) 2001-04-12 2006-04-04 Wyeth Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators
US7615234B2 (en) 2001-09-11 2009-11-10 Glide Pharmaceutical Technologies Limited Drug delivery technology
BR0212494A (pt) 2001-09-13 2004-08-24 Kissei Pharmaceutical Cristais de derivados de hidróxinorefedrina
US6723077B2 (en) 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
US6893655B2 (en) 2001-10-09 2005-05-17 3M Innovative Properties Co. Transdermal delivery devices
ES2327620T3 (es) 2001-11-16 2009-11-02 Astellas Pharma Inc. Derivado de 4,4-difluoro-1,2,3,4-tetraidro-5h-1-benzacepina o sales del mismo.
NZ535861A (en) 2002-05-07 2006-11-30 Ferring Bv Desmopressin acetate in an orodispersible dosage form that disintegrates in the mouth within 10 seconds
US6945952B2 (en) 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
JP2006500974A (ja) * 2002-06-28 2006-01-12 アルザ・コーポレーシヨン 被覆され微細突起物を有する経皮的薬物送達装置
GB2421689B (en) 2002-08-05 2007-03-07 Caretek Medical Ltd Drug delivery system
EP1590033A2 (en) 2002-09-30 2005-11-02 Alza Corporation Drug delivery device having coated microprojections incorporating vasoconstrictors
CA2501389C (en) 2002-10-09 2013-01-08 Toray Industries, Inc. Remedies or preventives for frequent urination or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group
US7383084B2 (en) 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
DE10259934B3 (de) 2002-12-20 2004-10-14 H.C. Starck Gmbh Verfahren zur Herstellung von Formteilen aus Niob oder Tantal durch elektrochemisches Ätzen und so erhältliche Formteile
AR042815A1 (es) 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US7385801B2 (en) 2003-03-31 2008-06-10 Fuji Jukogyo Kabushiki Kaisha Organic electrolyte capacitor
NZ542815A (en) 2003-04-28 2009-01-31 Astellas Pharma Inc 4,4-Difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof
US20060193825A1 (en) 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US7094545B2 (en) 2003-04-30 2006-08-22 Ferring Bv Pharmaceutical composition as solid dosage form and method for manufacturing thereof
EP1638468B1 (en) 2003-06-30 2007-08-15 Alza Corporation Method for coating skin piercing microprojections
ATE301990T1 (de) 2003-07-25 2005-09-15 Ferring Bv Pharmazeutische desmopressin-zubereitung als feste darreichungsform und methode zu ihrer herstellung
CN1826099B (zh) 2003-07-25 2010-06-09 凡林有限公司 固体剂型药物组合物及其制造方法
BRPI0413354A (pt) * 2003-08-04 2006-10-10 Alza Corp método e dispositivo para intensificar fluxo de agente transdérmico
US6930932B2 (en) 2003-08-27 2005-08-16 Hewlett-Packard Development Company, L.P. Data signal reception latch control using clock aligned relative to strobe signal
WO2005042054A2 (en) 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
WO2005044333A2 (en) 2003-10-31 2005-05-19 Alza Corporation Self-actuating applicator for microprojection array
CA2866501A1 (en) * 2003-11-10 2005-05-26 Allergan, Inc. Pharmaceutical compositions including low dosages of desmopressin
JP2005152180A (ja) * 2003-11-25 2005-06-16 Nano Device & System Research Inc インスリン投与用マイクロニードル
US7018653B2 (en) 2003-12-29 2006-03-28 Ferring B.V. Method for preparing solid dosage form of desmopressin
CN1946452A (zh) 2004-01-09 2007-04-11 阿尔扎公司 频率促进的药物透皮释放方法和系统
JP4556113B2 (ja) 2004-09-09 2010-10-06 株式会社ダイフク スタッカークレーン
HRP20160455T1 (hr) 2004-09-09 2016-07-15 Yeda Research And Development Co., Ltd. Smjese polipeptida, sastavi koji ih sadrže i postupci za njihovu pripremu, te njihove primjene
US7097776B2 (en) 2004-10-22 2006-08-29 Hewlett-Packard Development Company, L.P. Method of fabricating microneedles
US20080009801A1 (en) 2004-12-02 2008-01-10 Nickel Janice H Method for dispensing material into a drug delivery device
FR2879273A1 (fr) 2004-12-09 2006-06-16 Hutchinson Sa Dispositif anti-vibratoire hydraulique a entretoise
US7180274B2 (en) 2004-12-10 2007-02-20 Aimtron Technology Corp. Switching voltage regulator operating without a discontinuous mode
US20080262444A1 (en) * 2005-01-31 2008-10-23 Bioserentach Co., Ltd. Percutaneously Absorbable Preparation, Percutaneously Absorbable Preparation Holding Sheet, and Percutaneously Absorbable Preparation Holding Equipment
EP1845946A2 (en) 2005-02-10 2007-10-24 Orexo AB Pharmaceutical compositions useful in the transmucosal administration of drugs
US7856263B2 (en) 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
MX2007012883A (es) 2005-04-22 2007-12-10 Wyeth Corp Derivados de dihidrobenzofurano y usos de los mismos.
GT200600159A (es) 2005-04-22 2007-03-14 Derivados benzodioxano y benzodioxolano y usos de los mismos
AR056320A1 (es) 2005-04-22 2007-10-03 Wyeth Corp Derivados de cromano y cromeno, procesos de obtencion, composiciones farmaceuticas y usos de los mismos
US7368477B2 (en) 2005-04-22 2008-05-06 Wyeth Benzofuranyl alkanamine derivatives and uses thereof
MX2007012936A (es) 2005-04-22 2008-01-11 Wyeth Corp Derivados de dihidrobenzofurano y usos de los mismos.
TW200716106A (en) 2005-04-24 2007-05-01 Wyeth Corp Methods for modulating bladder function
WO2006138719A2 (en) 2005-06-17 2006-12-28 Georgia Tech Research Corporation Coated microstructures and method of manufacture thereof
EP1904158B1 (en) 2005-06-24 2013-07-24 3M Innovative Properties Company Collapsible patch with microneedle array
JP2007152745A (ja) 2005-12-05 2007-06-21 Tombow Pencil Co Ltd 加圧ペン
WO2007083323A2 (en) 2006-01-23 2007-07-26 Panacea Biotec Limited. Modified release oral dosage form comprising desmopressin
WO2007127976A2 (en) 2006-05-01 2007-11-08 Georgia Tech Research Corporation Particle based molding
CA2988753A1 (en) 2007-08-06 2009-02-12 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
WO2010075327A1 (en) 2008-12-22 2010-07-01 Serenity Pharmaceuticals Corporation Desmopressin composition
BRPI0923557A2 (pt) 2008-12-22 2016-01-26 Allergan Inc administração de desmopressina intranasal
PT4104848T (pt) 2009-06-18 2024-01-04 Acerus Pharmaceuticals Usa Llc Administração segura de desmopressina

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0278474A1 (en) * 1987-02-10 1988-08-17 Drug Delivery Systems Inc. Electrolytic transdermal delivery of polypeptides
US5848991A (en) * 1990-12-13 1998-12-15 Elan Medical Technologies Limited Athlone, Co. Intradermal drug delivery device and method for intradermal delivery of drugs
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
US20020016562A1 (en) * 1996-06-18 2002-02-07 Michel J. N. Cormier Device and method for enhancing transdermal flux of agents being delivered or sampled
RU2282468C2 (ru) * 2000-10-26 2006-08-27 Алза Корпорейшн Устройство для трансдермальной доставки лекарственных средств, имеющее микровыступы с покрытием
WO2004041153A2 (en) * 2002-05-07 2004-05-21 Fein Seymour H Pharmaceutical composition including low dosages of desmopressin
WO2005041871A2 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
US20060093658A1 (en) * 2004-10-26 2006-05-04 Gayatri Sathyan Apparatus and method for transdermal delivery of desmopressin

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MICHEL CORMIER et al., Transdermaldelivery of desmopressin using a coated microneedle array patch system., Journal of Controlled Release Volume 97, Issue 3, 7 July 2004, Pages 503-511, реферат, найдено из Интернет на сайте: http://www.sciencedirect.com/science/article/pii/S0168365904001713. *
MICHEL CORMIER et al., Transdermaldelivery of desmopressin using a coated microneedle array patch system., Journal of Controlled Release Volume 97, Issue 3, 7 July 2004, Pages 503-511, реферат, найдено из Интернет на сайте: http://www.sciencedirect.com/science/article/pii/S0168365904001713. NAKAKURA M, et al., Prolongation of antidiuretic response to desmopressin acetate by iontophoretic transdermal delivery in rats., Biol Pharm Bull. 1997 May; 20(5):537-40., реферат, найдено из Интернет на сайте: http://www.ncbi.nlm.nih.gov/pubmed/9178935. *
NAKAKURA M, et al., Prolongation of antidiuretic response to desmopressin acetate by iontophoretic transdermal delivery in rats., Biol Pharm Bull. 1997 May; 20(5):537-40., реферат, найдено из Интернет на сайте: http://www.ncbi.nlm.nih.gov/pubmed/9178935. *

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