RU2379033C2 - Комбинации, содержащие антимускариновые средства и бета-адренергические агонисты - Google Patents

Комбинации, содержащие антимускариновые средства и бета-адренергические агонисты Download PDF

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Publication number
RU2379033C2
RU2379033C2 RU2006146673/15A RU2006146673A RU2379033C2 RU 2379033 C2 RU2379033 C2 RU 2379033C2 RU 2006146673/15 A RU2006146673/15 A RU 2006146673/15A RU 2006146673 A RU2006146673 A RU 2006146673A RU 2379033 C2 RU2379033 C2 RU 2379033C2
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Prior art keywords
agonist
combination
antagonist
treatment
respiratory disease
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RU2006146673/15A
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Russian (ru)
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RU2006146673A (ru
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ЭСКАРДО Хорди ГРАС (ES)
Эскардо Хорди Грас
КАЛЬВО Хесус ЛЬЕНАС (ES)
КАЛЬВО Хесус ЛЬЕНАС
Хамиш РАЙДЕР (ES)
Хамиш РАЙДЕР
ДИАС Пио ОРВИС (ES)
Диас Пио Орвис
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Лабораториос Альмираль, С.А.
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Priority claimed from ES200401312A external-priority patent/ES2257152B1/es
Application filed by Лабораториос Альмираль, С.А. filed Critical Лабораториос Альмираль, С.А.
Publication of RU2006146673A publication Critical patent/RU2006146673A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2006146673/15A 2004-05-31 2005-05-31 Комбинации, содержащие антимускариновые средства и бета-адренергические агонисты RU2379033C2 (ru)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
ESP200401312 2004-05-31
ES200401312A ES2257152B1 (es) 2004-05-31 2004-05-31 Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
EPPCT/EP2005/001969 2005-02-24
EP2005001969 2005-02-24
GB2005000740 2005-02-25
GBPCT/GB2005/000740 2005-02-25
GBPCT/GB2005/000722 2005-02-25
GB2005000722 2005-02-25

Publications (2)

Publication Number Publication Date
RU2006146673A RU2006146673A (ru) 2008-07-20
RU2379033C2 true RU2379033C2 (ru) 2010-01-20

Family

ID=34968792

Family Applications (3)

Application Number Title Priority Date Filing Date
RU2006146813/15A RU2385156C2 (ru) 2004-05-31 2005-05-31 Комбинации, содержащие антимускариновые средства и кортикостероиды
RU2006147269/15A RU2404772C2 (ru) 2004-05-31 2005-05-31 Комбинации, содержащие противомускариновые средства и ингибиторы pde4
RU2006146673/15A RU2379033C2 (ru) 2004-05-31 2005-05-31 Комбинации, содержащие антимускариновые средства и бета-адренергические агонисты

Family Applications Before (2)

Application Number Title Priority Date Filing Date
RU2006146813/15A RU2385156C2 (ru) 2004-05-31 2005-05-31 Комбинации, содержащие антимускариновые средства и кортикостероиды
RU2006147269/15A RU2404772C2 (ru) 2004-05-31 2005-05-31 Комбинации, содержащие противомускариновые средства и ингибиторы pde4

Country Status (21)

Country Link
US (2) US20110224177A1 (OSRAM)
EP (5) EP1765405A1 (OSRAM)
JP (1) JP2012211183A (OSRAM)
AT (3) ATE419011T1 (OSRAM)
AU (3) AU2005247105B2 (OSRAM)
BE (1) BE2015C012I2 (OSRAM)
CA (3) CA2568568C (OSRAM)
CY (1) CY1110829T1 (OSRAM)
DE (3) DE602005022499D1 (OSRAM)
DK (2) DK1891974T3 (OSRAM)
ES (2) ES2317245T3 (OSRAM)
HR (3) HRP20090106T3 (OSRAM)
IL (3) IL179685A (OSRAM)
MX (3) MXPA06013850A (OSRAM)
NZ (3) NZ551670A (OSRAM)
PL (2) PL1905451T3 (OSRAM)
PT (3) PT1765404E (OSRAM)
RS (3) RS51422B (OSRAM)
RU (3) RU2385156C2 (OSRAM)
SI (3) SI1891974T1 (OSRAM)
WO (3) WO2005115463A1 (OSRAM)

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GB0921075D0 (en) * 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
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TR201802725T4 (tr) * 2013-03-15 2018-03-21 Verona Pharma Plc İlaç kombinasyonu.
GB201308933D0 (en) * 2013-05-17 2013-07-03 Diurnal Ltd Paediatric composition
EP3018209B1 (en) * 2013-07-05 2019-10-16 Bioneer Corporation Respiratory disease-related gene specific sirna, double-helical oligo rna structure containing sirna, compositon containing same for preventing or treating respiratory disease
TW201542207A (zh) * 2013-10-03 2015-11-16 Otsuka Pharma Co Ltd 嚴重氣喘治療劑

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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001004118A2 (en) * 1999-07-14 2001-01-18 Almirall Prodesfarma S.A. Quinuclidine derivatives and their use as muscarinic m3 receptor ligands
WO2002053564A2 (en) * 2000-12-28 2002-07-11 Almirall Prodesfarma Ag Quinuclidine derivatives and their use as m3 antagonists
WO2003000241A2 (de) * 2001-06-23 2003-01-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue arzneimittelkompositionen auf der basis von anticholinergika; corticosteroiden und betamimetika zur behandlung von entzündlichen und/oder obstruktiven atemwegserkrankungen
WO2003087094A2 (en) * 2002-04-16 2003-10-23 Almirall Prodesfarma Ag Pyrrolidinium derivatives as antagonists of m3 muscarinic receptors

Also Published As

Publication number Publication date
RS51206B (sr) 2010-12-31
RS51422B (en) 2011-02-28
WO2005115465A1 (en) 2005-12-08
CA2569074A1 (en) 2005-12-08
US20110224177A1 (en) 2011-09-15
EP1905451B1 (en) 2010-01-13
PL1905451T3 (pl) 2010-05-31
PT1891974E (pt) 2010-09-27
PT1905451E (pt) 2010-03-31
CA2568568C (en) 2012-12-18
MXPA06013849A (es) 2007-03-01
CA2569074C (en) 2012-12-18
RU2006146813A (ru) 2008-07-20
CA2568568A1 (en) 2005-12-08
MXPA06013846A (es) 2007-03-01
PL1891974T3 (pl) 2010-12-31
RU2385156C2 (ru) 2010-03-27
WO2005115464A1 (en) 2005-12-08
NZ551670A (en) 2010-07-30
EP2210614A1 (en) 2010-07-28
EP1765405A1 (en) 2007-03-28
CA2568571C (en) 2012-12-18
RS50786B (sr) 2010-08-31
HRP20100104T1 (hr) 2010-04-30
EP1891974A1 (en) 2008-02-27
EP1761279A1 (en) 2007-03-14
DK1891974T3 (da) 2010-11-08
AU2005247106B2 (en) 2010-11-11
ATE419011T1 (de) 2009-01-15
SI1765404T1 (sl) 2009-04-30
RU2404772C2 (ru) 2010-11-27
AU2005247105B2 (en) 2010-11-11
AU2005247104B2 (en) 2010-11-11
RU2006146673A (ru) 2008-07-20
NZ551669A (en) 2010-07-30
EP1905451A1 (en) 2008-04-02
MXPA06013850A (es) 2007-03-02
CA2568571A1 (en) 2005-12-08
EP1891974B1 (en) 2010-07-21
DE602005012102D1 (de) 2009-02-12
SI1905451T1 (sl) 2010-05-31
WO2005115463A1 (en) 2005-12-08
AU2005247105A1 (en) 2005-12-08
ES2317245T3 (es) 2009-04-16
DK1905451T3 (da) 2010-05-10
HK1096605A1 (en) 2007-06-08
AU2005247104A1 (en) 2005-12-08
IL179690A0 (en) 2007-05-15
IL179686A0 (en) 2007-05-15
IL179685A (en) 2012-01-31
ATE454904T1 (de) 2010-01-15
CY1110829T1 (el) 2015-06-10
SI1891974T1 (sl) 2010-11-30
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