RU2353356C2 - Применение производных ациламиноалкениленамида для лечения нарушений функциональной подвижности внутренних органов - Google Patents

Применение производных ациламиноалкениленамида для лечения нарушений функциональной подвижности внутренних органов Download PDF

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Publication number
RU2353356C2
RU2353356C2 RU2004127132/15A RU2004127132A RU2353356C2 RU 2353356 C2 RU2353356 C2 RU 2353356C2 RU 2004127132/15 A RU2004127132/15 A RU 2004127132/15A RU 2004127132 A RU2004127132 A RU 2004127132A RU 2353356 C2 RU2353356 C2 RU 2353356C2
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RU
Russia
Prior art keywords
methyl
amino
bis
trifluoromethylbenzoyl
caprolactam
Prior art date
Application number
RU2004127132/15A
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English (en)
Russian (ru)
Other versions
RU2004127132A (ru
Inventor
Джон Р. ФОЗАРД (FR)
Джон Р. ФОЗАРД
Эккхард ВЕБЕР (CH)
Эккхард ВЕБЕР
Ханс-Юрген ПФАННКУХЕ (DE)
Ханс-Юрген ПФАННКУХЕ
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Новартис Аг
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Application filed by Новартис Аг filed Critical Новартис Аг
Publication of RU2004127132A publication Critical patent/RU2004127132A/ru
Application granted granted Critical
Publication of RU2353356C2 publication Critical patent/RU2353356C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
RU2004127132/15A 2002-02-08 2003-02-07 Применение производных ациламиноалкениленамида для лечения нарушений функциональной подвижности внутренних органов RU2353356C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0203061.7 2002-02-08
GBGB0203061.7A GB0203061D0 (en) 2002-02-08 2002-02-08 Organic compounds

Publications (2)

Publication Number Publication Date
RU2004127132A RU2004127132A (ru) 2005-06-10
RU2353356C2 true RU2353356C2 (ru) 2009-04-27

Family

ID=9930743

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004127132/15A RU2353356C2 (ru) 2002-02-08 2003-02-07 Применение производных ациламиноалкениленамида для лечения нарушений функциональной подвижности внутренних органов

Country Status (18)

Country Link
US (2) US20050203164A1 (enExample)
EP (2) EP1476167A1 (enExample)
JP (2) JP2005516994A (enExample)
KR (2) KR20040081492A (enExample)
CN (1) CN1301714C (enExample)
AU (1) AU2003244446B2 (enExample)
BR (1) BR0307479A (enExample)
CA (1) CA2471964A1 (enExample)
GB (1) GB0203061D0 (enExample)
IL (2) IL162816A0 (enExample)
MX (1) MXPA04007640A (enExample)
NO (1) NO20043735L (enExample)
NZ (1) NZ534231A (enExample)
PL (1) PL370255A1 (enExample)
RU (1) RU2353356C2 (enExample)
TW (1) TWI330177B (enExample)
WO (1) WO2003066062A1 (enExample)
ZA (1) ZA200404960B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203061D0 (en) * 2002-02-08 2002-03-27 Novartis Ag Organic compounds
CA2543552A1 (en) * 2003-10-27 2005-05-06 Novartis Ag Use of neurokinin antagonists in the treatment of urinary incontinence
CN101568331A (zh) 2006-09-08 2009-10-28 奥尔制药有限公司 减少或缓解消化道炎症的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5929067A (en) * 1995-02-22 1999-07-27 Novartis Ag 1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists
RU2161894C1 (ru) * 1999-08-10 2001-01-20 НИФ "Ультрасан" Лечебно-профилактическая композиция
US6319917B1 (en) * 1996-08-22 2001-11-20 Novartis Ag Acylaminoalkenylene-amide derivatives as NK1 and NK2 antagonists

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217996A (en) * 1992-01-22 1993-06-08 Ciba-Geigy Corporation Biaryl substituted 4-amino-butyric acid amides
US5457101A (en) * 1994-06-03 1995-10-10 Eli Lilly And Company Thieno[1,5]benzoidiazepine use
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
GB9525296D0 (en) * 1995-12-11 1996-02-07 Merck Sharp & Dohme Therapeutic agents
GB9708484D0 (en) * 1997-04-25 1997-06-18 Merck Sharp & Dohme Therapeutic agents
TR199903299T2 (xx) * 1997-07-02 2000-07-21 Merck & Co., Inc. Ta�ikinin resept�r antagonisti 2-(R)-(1-(R)- (3,5-Bis(triflorometil) Fenil)Etoksi-3-(S)- (4-Floro)Fenil-4- (3-5(-okso-1H,4H-1,2,4-Triazolo) metilmorfolin'in polimorfik formu.
TW520370B (en) * 1998-11-20 2003-02-11 Meiji Seika Kaisha Benzooxazole derivatives and a pharmaceutical composition containing the derivatives as an active ingredient
GB0010958D0 (en) 2000-05-05 2000-06-28 Novartis Ag Organic compounds
CA2432543A1 (en) * 2000-12-22 2002-07-04 Takeda Chemical Industries, Ltd. Combination drugs
GB0203061D0 (en) * 2002-02-08 2002-03-27 Novartis Ag Organic compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5929067A (en) * 1995-02-22 1999-07-27 Novartis Ag 1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists
US6319917B1 (en) * 1996-08-22 2001-11-20 Novartis Ag Acylaminoalkenylene-amide derivatives as NK1 and NK2 antagonists
RU2161894C1 (ru) * 1999-08-10 2001-01-20 НИФ "Ультрасан" Лечебно-профилактическая композиция

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Беликов В.Г. Фармацевтическая химия. - М.: Высшая школа, 1993, т.1, с.43-47. *

Also Published As

Publication number Publication date
AU2003244446A1 (en) 2003-09-02
NO20043735L (no) 2004-09-07
US20050203164A1 (en) 2005-09-15
JP2005516994A (ja) 2005-06-09
PL370255A1 (en) 2005-05-16
AU2003244446B2 (en) 2006-08-10
TWI330177B (en) 2010-09-11
CN1301714C (zh) 2007-02-28
EP2216025A3 (en) 2010-11-10
HK1077749A1 (en) 2006-02-24
KR20100100994A (ko) 2010-09-15
BR0307479A (pt) 2004-12-07
CA2471964A1 (en) 2003-08-14
US20070293473A1 (en) 2007-12-20
TW200302818A (en) 2003-08-16
KR20040081492A (ko) 2004-09-21
GB0203061D0 (en) 2002-03-27
CN1627947A (zh) 2005-06-15
EP2216025A2 (en) 2010-08-11
JP2010241835A (ja) 2010-10-28
IL162816A (en) 2010-11-30
IL162816A0 (en) 2005-11-20
RU2004127132A (ru) 2005-06-10
MXPA04007640A (es) 2004-11-10
NZ534231A (en) 2007-02-23
ZA200404960B (en) 2006-05-31
EP1476167A1 (en) 2004-11-17
WO2003066062A1 (en) 2003-08-14

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20090208

MM4A The patent is invalid due to non-payment of fees

Effective date: 20120208