RU2323218C2 - Новые производные 1,4-диазабициклоалкана и фармацевтическая композиция на их основе - Google Patents

Info

Publication number

RU2323218C2

RU2323218C2 RU2005105048/04A RU2005105048A RU2323218C2 RU 2323218 C2 RU2323218 C2 RU 2323218C2 RU 2005105048/04 A RU2005105048/04 A RU 2005105048/04A RU 2005105048 A RU2005105048 A RU 2005105048A RU 2323218 C2 RU2323218 C2 RU 2323218C2

Authority

RU

Russia

Prior art keywords

diazabicyclo

nonane

oxadiazol

compound

group

Prior art date

2002-09-30

Links

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• 150000001875 compounds Chemical class 0.000 claims abstract description 183
• 150000003839 salts Chemical class 0.000 claims abstract description 42
• 125000003118 aryl group Chemical group 0.000 claims abstract description 17
• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 12
• 125000001072 heteroaryl group Chemical group 0.000 claims abstract description 8
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 8
• NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 6
• 125000006615 aromatic heterocyclic group Chemical group 0.000 claims abstract description 6
• 125000005842 heteroatom Chemical group 0.000 claims abstract description 6
• 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 6
• 125000004430 oxygen atom Chemical group O* 0.000 claims abstract description 6
• 229910052717 sulfur Inorganic materials 0.000 claims abstract description 6
• 239000011593 sulfur Substances 0.000 claims abstract description 6
• 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims abstract description 4
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• 229910052736 halogen Inorganic materials 0.000 claims description 8
• 150000002367 halogens Chemical class 0.000 claims description 8
• 229910052799 carbon Inorganic materials 0.000 claims description 7
• NFQNAHNFWFCCMJ-UHFFFAOYSA-N 2-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-5-phenyl-1,3,4-oxadiazole Chemical compound C1CN(CC2)CCC1N2C(O1)=NN=C1C1=CC=CC=C1 NFQNAHNFWFCCMJ-UHFFFAOYSA-N 0.000 claims description 6
• DZQAGBGRTLEXOZ-UHFFFAOYSA-N 2-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-5-thiophen-2-yl-1,3,4-oxadiazole Chemical compound C1CN(CC2)CCC1N2C(O1)=NN=C1C1=CC=CS1 DZQAGBGRTLEXOZ-UHFFFAOYSA-N 0.000 claims description 5
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• HEOSAVOMNPCPTH-UHFFFAOYSA-N 2-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole Chemical compound C1=CC(OC)=CC=C1C1=NN=C(N2C3CCN(CC3)CC2)O1 HEOSAVOMNPCPTH-UHFFFAOYSA-N 0.000 claims description 4
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• DFHCJJQBWFESQY-UHFFFAOYSA-N 2-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-5-pyridin-2-yl-1,3,4-oxadiazole Chemical compound C1CN(CC2)CCC1N2C(O1)=NN=C1C1=CC=CC=N1 DFHCJJQBWFESQY-UHFFFAOYSA-N 0.000 claims description 4
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