RU2300373C2 - Карбаматы для предотвращения или лечения нейродегенеративных нарушений - Google Patents
Карбаматы для предотвращения или лечения нейродегенеративных нарушений Download PDFInfo
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- RU2300373C2 RU2300373C2 RU2003128982/14A RU2003128982A RU2300373C2 RU 2300373 C2 RU2300373 C2 RU 2300373C2 RU 2003128982/14 A RU2003128982/14 A RU 2003128982/14A RU 2003128982 A RU2003128982 A RU 2003128982A RU 2300373 C2 RU2300373 C2 RU 2300373C2
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27168201P | 2001-02-27 | 2001-02-27 | |
| US60/271,682 | 2001-02-27 | ||
| US10/081,764 | 2002-02-21 | ||
| US10/081,764 US20020165273A1 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating neurodegenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2003128982A RU2003128982A (ru) | 2005-03-10 |
| RU2300373C2 true RU2300373C2 (ru) | 2007-06-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2003128982/14A RU2300373C2 (ru) | 2001-02-27 | 2002-02-21 | Карбаматы для предотвращения или лечения нейродегенеративных нарушений |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US20020165273A1 (https=) |
| EP (1) | EP1383489B1 (https=) |
| JP (1) | JP4276840B2 (https=) |
| KR (1) | KR100910928B1 (https=) |
| CN (1) | CN1235579C (https=) |
| AR (1) | AR035756A1 (https=) |
| AT (1) | ATE361745T1 (https=) |
| BR (1) | BR0207645A (https=) |
| CA (1) | CA2439295C (https=) |
| CY (1) | CY1106753T1 (https=) |
| CZ (1) | CZ301203B6 (https=) |
| DE (1) | DE60220043T2 (https=) |
| DK (1) | DK1383489T3 (https=) |
| ES (1) | ES2284845T3 (https=) |
| HU (1) | HUP0303264A3 (https=) |
| IL (2) | IL157591A0 (https=) |
| MX (1) | MXPA03007718A (https=) |
| MY (1) | MY138156A (https=) |
| NO (1) | NO20033798L (https=) |
| NZ (1) | NZ527990A (https=) |
| PL (1) | PL364680A1 (https=) |
| PT (1) | PT1383489E (https=) |
| RS (1) | RS51055B (https=) |
| RU (1) | RU2300373C2 (https=) |
| TW (1) | TWI312679B (https=) |
| WO (1) | WO2002067925A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005033092A1 (en) * | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | Chroman derivatives |
| DK1809273T3 (da) * | 2004-09-16 | 2010-08-02 | Janssen Pharmaceutica Nv | Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese |
| BRPI0516112A (pt) * | 2004-10-15 | 2008-08-26 | Janssen Pharmaceutica Nv | métodos para neuroproteção |
| US20070021500A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods for neuroprotection |
| ES2385087T3 (es) * | 2005-07-26 | 2012-07-18 | Sk Biopharmaceuticals Co., Ltd | Procedimientos para tratar trastornos relacionados con sustancias |
| JP2010505856A (ja) * | 2006-10-06 | 2010-02-25 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | （ｓ）−（＋）−２−（２−クロロフェニル）−２−ヒドロキシ−エチルカルバメートの新規結晶 |
| EP2081648A2 (en) * | 2006-10-30 | 2009-07-29 | Janssen Pharmaceutica, N.V. | Carbamate compounds for use in treating depression |
| BRPI0718323A2 (pt) * | 2006-10-31 | 2013-11-26 | Janssen Pharmaceutica Nv | Tratamento de transtornos invasivos do desenvolvimento. |
| CN104628603B (zh) * | 2010-07-02 | 2017-08-15 | 比皮艾思药物研发有限公司 | 苯基氨基甲酸酯化合物及含有苯基氨基甲酸酯化合物的肌肉松弛剂 |
| US9018253B2 (en) | 2010-07-02 | 2015-04-28 | Bio-Pharm Solutions Co., Ltd. | Phenylcarbamate compound and muscle relaxant containing the same |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| US20130060024A1 (en) * | 2011-09-07 | 2013-03-07 | Satori Pharmaceuticals, Inc. | Compounds useful for treating neurodegenerative disorders |
| MX353024B (es) | 2011-12-27 | 2017-12-18 | Bio Pharm Solutions Co Ltd | Compuestos de fenil carbamato para uso en la prevencion o tratamiento de epilepsia. |
| CN105189451A (zh) * | 2013-03-12 | 2015-12-23 | 比皮艾思药物研发有限公司 | 氨基甲酸苯酯化合物和包含该化合物的用于预防或治疗神经性毒气引起的疾病的组合物 |
| CN109939092B (zh) | 2013-03-12 | 2022-03-22 | 比皮艾思药物研发有限公司 | 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物 |
| WO2017150903A1 (en) | 2016-02-29 | 2017-09-08 | Bio-Pharm Solutions Co., Ltd. | Sulfamate derivative compounds, processes for preparing them and their uses |
| EP3556365B1 (en) * | 2016-12-14 | 2025-07-02 | SK Biopharmaceuticals Co., Ltd. | Use of carbamate compound for prevention, alleviation, or treatment of demyelinating disease |
| ES2978226T3 (es) * | 2018-09-21 | 2024-09-09 | Sk Biopharmaceuticals Co Ltd | Compuesto de carbamato y uso de la formulación que lo comprende para prevenir, aliviar o tratar el trastorno de estrés agudo o el trastorno de estrés postraumático |
| KR20230044274A (ko) * | 2020-08-31 | 2023-04-03 | (주)바이오팜솔루션즈 | 신경퇴행성 질환의 예방 또는 치료용 페닐 알킬 카바메이트 화합물 |
| KR20230051206A (ko) | 2020-09-10 | 2023-04-17 | (주)바이오팜솔루션즈 | 정신질환 치료 또는 완화용 설파메이트 유도체 화합물 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3278380A (en) * | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
| RU2136670C1 (ru) * | 1994-02-03 | 1999-09-10 | Синтелябо | Производные 3-(2-аминоэтил)-4-[3-(трифторметил)бензоил]-3,4-дигидро-2h-1,4- бензоксазина, способ их получения и содержащий их фармацевтический состав |
| US6103759A (en) * | 1996-01-16 | 2000-08-15 | Sk Corporation | Halogen substituted carbamate compounds from 2-phenyl-1, 2-ethanediol |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US5474990A (en) * | 1989-10-20 | 1995-12-12 | Olney; John W. | Barbiturates as safening agents in conjunction with NMDA antagonists |
| US5492930A (en) * | 1994-04-25 | 1996-02-20 | Schering Corporation | Method and formulation for treating CNS disorders |
| US5728728A (en) * | 1996-04-10 | 1998-03-17 | Kozachuk; Walter E. | Methods of providing neuroprotection |
| US6232434B1 (en) * | 1996-08-02 | 2001-05-15 | Duke University Medical Center | Polymers for delivering nitric oxide in vivo |
| KR100886578B1 (ko) * | 2001-02-27 | 2009-03-05 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 카바메이트 화합물을 포함하는 정신증 장애 예방용 또는 치료용 약제학적 조성물 |
| ES2262801T3 (es) * | 2001-02-27 | 2006-12-01 | Ortho-Mcneil Pharmaceutical, Inc. | Uso de un compuesto de carbamato para la prevencion o el tratamiento de trastorno bipolar. |
| PT1411917E (pt) * | 2001-02-27 | 2007-09-17 | Ortho Mcneil Pharm Inc | ''compostos carbamatos para utilização na prevenção ou tratamento de distúrbios do movimento'' |
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2002
- 2002-02-21 EP EP02714977A patent/EP1383489B1/en not_active Expired - Lifetime
- 2002-02-21 DK DK02714977T patent/DK1383489T3/da active
- 2002-02-21 WO PCT/US2002/005541 patent/WO2002067925A1/en not_active Ceased
- 2002-02-21 BR BR0207645-4A patent/BR0207645A/pt not_active Application Discontinuation
- 2002-02-21 DE DE60220043T patent/DE60220043T2/de not_active Expired - Lifetime
- 2002-02-21 AT AT02714977T patent/ATE361745T1/de active
- 2002-02-21 PL PL02364680A patent/PL364680A1/xx unknown
- 2002-02-21 JP JP2002567292A patent/JP4276840B2/ja not_active Expired - Fee Related
- 2002-02-21 IL IL15759102A patent/IL157591A0/xx unknown
- 2002-02-21 MX MXPA03007718A patent/MXPA03007718A/es active IP Right Grant
- 2002-02-21 CA CA2439295A patent/CA2439295C/en not_active Expired - Fee Related
- 2002-02-21 CZ CZ20032313A patent/CZ301203B6/cs not_active IP Right Cessation
- 2002-02-21 RS YUP-674/03A patent/RS51055B/sr unknown
- 2002-02-21 KR KR1020037011302A patent/KR100910928B1/ko not_active Expired - Fee Related
- 2002-02-21 CN CNB028087178A patent/CN1235579C/zh not_active Expired - Fee Related
- 2002-02-21 US US10/081,764 patent/US20020165273A1/en not_active Abandoned
- 2002-02-21 PT PT02714977T patent/PT1383489E/pt unknown
- 2002-02-21 NZ NZ527990A patent/NZ527990A/en unknown
- 2002-02-21 RU RU2003128982/14A patent/RU2300373C2/ru not_active IP Right Cessation
- 2002-02-21 HU HU0303264A patent/HUP0303264A3/hu unknown
- 2002-02-21 ES ES02714977T patent/ES2284845T3/es not_active Expired - Lifetime
- 2002-02-27 TW TW091103504A patent/TWI312679B/zh active
- 2002-02-27 AR ARP020100697A patent/AR035756A1/es unknown
- 2002-02-27 MY MYPI20020697A patent/MY138156A/en unknown
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2003
- 2003-08-26 IL IL157591A patent/IL157591A/en not_active IP Right Cessation
- 2003-08-26 NO NO20033798A patent/NO20033798L/no not_active Application Discontinuation
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2004
- 2004-03-10 US US10/797,795 patent/US20040171679A1/en not_active Abandoned
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2007
- 2007-07-24 CY CY20071100982T patent/CY1106753T1/el unknown
-
2008
- 2008-09-10 US US12/207,816 patent/US20090005442A1/en not_active Abandoned
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| US3278380A (en) * | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
| RU2136670C1 (ru) * | 1994-02-03 | 1999-09-10 | Синтелябо | Производные 3-(2-аминоэтил)-4-[3-(трифторметил)бензоил]-3,4-дигидро-2h-1,4- бензоксазина, способ их получения и содержащий их фармацевтический состав |
| US6103759A (en) * | 1996-01-16 | 2000-08-15 | Sk Corporation | Halogen substituted carbamate compounds from 2-phenyl-1, 2-ethanediol |
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| АЛЬТШУЛЕР В.Б. и др. Стандарты (модели протоколов) диагностики и лечения наркологических больных. Приказ №140 МЗ РФ от 28.04.1998 Найдено из Интернет: <URL: http://medi.net.ru/pract/standart/s01_a.shtml. CHEN D.M. Effects of sodium diethyldithiocarbamate on ischemia-reperfusion-induced brain injury in Mongolian gerbil. Zhongguo Yao Li Xue Bao. 1994 Sep; 15(5): 469-72. * |
| МАНЕЕЛОВ Л.С.Начальные проявления недостаточности кровоснабжения мозга (лечение, профилактика, трудоспособность). «Лечащий врач», 2000, №5-6. Найдено из Интернет: <URL: http://hghltd.yandex.com/. * |
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