KR100910928B1 - 신경퇴행성 질환의 예방 또는 치료용의 카바메이트 화합물 함유 약제학적 조성물 - Google Patents

신경퇴행성 질환의 예방 또는 치료용의 카바메이트 화합물 함유 약제학적 조성물 Download PDF

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KR100910928B1
KR100910928B1 KR1020037011302A KR20037011302A KR100910928B1 KR 100910928 B1 KR100910928 B1 KR 100910928B1 KR 1020037011302 A KR1020037011302 A KR 1020037011302A KR 20037011302 A KR20037011302 A KR 20037011302A KR 100910928 B1 KR100910928 B1 KR 100910928B1
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disease
formula
compound
delete delete
dementia
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KR20030076714A (ko
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플라타-살라만카를로스알
자오보유
트와이만로이이
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오르토-맥네일 파마슈티칼, 인코퍼레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
KR1020037011302A 2001-02-27 2002-02-21 신경퇴행성 질환의 예방 또는 치료용의 카바메이트 화합물 함유 약제학적 조성물 Expired - Fee Related KR100910928B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27168201P 2001-02-27 2001-02-27
US60/271,682 2001-02-27
US10/081,764 2002-02-21
US10/081,764 US20020165273A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating neurodegenerative disorders
PCT/US2002/005541 WO2002067925A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating neurodegenerative disorders

Publications (2)

Publication Number Publication Date
KR20030076714A KR20030076714A (ko) 2003-09-26
KR100910928B1 true KR100910928B1 (ko) 2009-08-06

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KR1020037011302A Expired - Fee Related KR100910928B1 (ko) 2001-02-27 2002-02-21 신경퇴행성 질환의 예방 또는 치료용의 카바메이트 화합물 함유 약제학적 조성물

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US (3) US20020165273A1 (https=)
EP (1) EP1383489B1 (https=)
JP (1) JP4276840B2 (https=)
KR (1) KR100910928B1 (https=)
CN (1) CN1235579C (https=)
AR (1) AR035756A1 (https=)
AT (1) ATE361745T1 (https=)
BR (1) BR0207645A (https=)
CA (1) CA2439295C (https=)
CY (1) CY1106753T1 (https=)
CZ (1) CZ301203B6 (https=)
DE (1) DE60220043T2 (https=)
DK (1) DK1383489T3 (https=)
ES (1) ES2284845T3 (https=)
HU (1) HUP0303264A3 (https=)
IL (2) IL157591A0 (https=)
MX (1) MXPA03007718A (https=)
MY (1) MY138156A (https=)
NO (1) NO20033798L (https=)
NZ (1) NZ527990A (https=)
PL (1) PL364680A1 (https=)
PT (1) PT1383489E (https=)
RS (1) RS51055B (https=)
RU (1) RU2300373C2 (https=)
TW (1) TWI312679B (https=)
WO (1) WO2002067925A1 (https=)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
WO2014142550A1 (en) * 2013-03-12 2014-09-18 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a psychiatric disorder comprising the same
US9682059B2 (en) 2013-03-12 2017-06-20 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compounds for use in preventing or treating epilepsy or epilepsy-related syndrome

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WO2005033092A1 (en) * 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. Chroman derivatives
DK1809273T3 (da) * 2004-09-16 2010-08-02 Janssen Pharmaceutica Nv Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese
BRPI0516112A (pt) * 2004-10-15 2008-08-26 Janssen Pharmaceutica Nv métodos para neuroproteção
US20070021500A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods for neuroprotection
ES2385087T3 (es) * 2005-07-26 2012-07-18 Sk Biopharmaceuticals Co., Ltd Procedimientos para tratar trastornos relacionados con sustancias
JP2010505856A (ja) * 2006-10-06 2010-02-25 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ （ｓ）−（＋）−２−（２−クロロフェニル）−２−ヒドロキシ−エチルカルバメートの新規結晶
EP2081648A2 (en) * 2006-10-30 2009-07-29 Janssen Pharmaceutica, N.V. Carbamate compounds for use in treating depression
BRPI0718323A2 (pt) * 2006-10-31 2013-11-26 Janssen Pharmaceutica Nv Tratamento de transtornos invasivos do desenvolvimento.
CN104628603B (zh) * 2010-07-02 2017-08-15 比皮艾思药物研发有限公司 苯基氨基甲酸酯化合物及含有苯基氨基甲酸酯化合物的肌肉松弛剂
US9018253B2 (en) 2010-07-02 2015-04-28 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
US20130060024A1 (en) * 2011-09-07 2013-03-07 Satori Pharmaceuticals, Inc. Compounds useful for treating neurodegenerative disorders
MX353024B (es) 2011-12-27 2017-12-18 Bio Pharm Solutions Co Ltd Compuestos de fenil carbamato para uso en la prevencion o tratamiento de epilepsia.
WO2017150903A1 (en) 2016-02-29 2017-09-08 Bio-Pharm Solutions Co., Ltd. Sulfamate derivative compounds, processes for preparing them and their uses
EP3556365B1 (en) * 2016-12-14 2025-07-02 SK Biopharmaceuticals Co., Ltd. Use of carbamate compound for prevention, alleviation, or treatment of demyelinating disease
ES2978226T3 (es) * 2018-09-21 2024-09-09 Sk Biopharmaceuticals Co Ltd Compuesto de carbamato y uso de la formulación que lo comprende para prevenir, aliviar o tratar el trastorno de estrés agudo o el trastorno de estrés postraumático
KR20230044274A (ko) * 2020-08-31 2023-04-03 (주)바이오팜솔루션즈 신경퇴행성 질환의 예방 또는 치료용 페닐 알킬 카바메이트 화합물
KR20230051206A (ko) 2020-09-10 2023-04-17 (주)바이오팜솔루션즈 정신질환 치료 또는 완화용 설파메이트 유도체 화합물

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US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US6403759B2 (en) * 1996-08-02 2002-06-11 Duke University Polymers for delivering nitric oxide in vivo

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US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US5474990A (en) * 1989-10-20 1995-12-12 Olney; John W. Barbiturates as safening agents in conjunction with NMDA antagonists
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
US5492930A (en) * 1994-04-25 1996-02-20 Schering Corporation Method and formulation for treating CNS disorders
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US5728728A (en) * 1996-04-10 1998-03-17 Kozachuk; Walter E. Methods of providing neuroprotection
KR100886578B1 (ko) * 2001-02-27 2009-03-05 오르토-맥네일 파마슈티칼, 인코퍼레이티드 카바메이트 화합물을 포함하는 정신증 장애 예방용 또는 치료용 약제학적 조성물
ES2262801T3 (es) * 2001-02-27 2006-12-01 Ortho-Mcneil Pharmaceutical, Inc. Uso de un compuesto de carbamato para la prevencion o el tratamiento de trastorno bipolar.
PT1411917E (pt) * 2001-02-27 2007-09-17 Ortho Mcneil Pharm Inc ''compostos carbamatos para utilização na prevenção ou tratamento de distúrbios do movimento''

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US6403759B2 (en) * 1996-08-02 2002-06-11 Duke University Polymers for delivering nitric oxide in vivo

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014142550A1 (en) * 2013-03-12 2014-09-18 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a psychiatric disorder comprising the same
WO2014142547A1 (en) * 2013-03-12 2014-09-18 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for neuroprotection comprising the same
WO2014142548A1 (en) * 2013-03-12 2014-09-18 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a nerve gas-induced disease comprising the same
WO2014142549A1 (en) * 2013-03-12 2014-09-18 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same
US9457003B2 (en) 2013-03-12 2016-10-04 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a nerve gas-induced disease comprising the same
US9566261B2 (en) 2013-03-12 2017-02-14 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same
KR20170058447A (ko) * 2013-03-12 2017-05-26 (주)바이오팜솔루션즈 페닐카바메이트 화합물 및 이를 포함하는 신경보호용 조성물
US9682059B2 (en) 2013-03-12 2017-06-20 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compounds for use in preventing or treating epilepsy or epilepsy-related syndrome
US9872847B2 (en) 2013-03-12 2018-01-23 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compounds for use in preventing or treating a movement disorder
US9907776B2 (en) 2013-03-12 2018-03-06 Bio-Pharm Solutions, Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a psychiatric disorder comprising the same
KR102014615B1 (ko) * 2013-03-12 2019-08-27 (주)바이오팜솔루션즈 페닐카바메이트 화합물 및 이를 포함하는 신경보호용 조성물
US10525030B2 (en) 2013-03-12 2020-01-07 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for neuroprotection comprising the same

Also Published As

Publication number Publication date
EP1383489B1 (en) 2007-05-09
ES2284845T3 (es) 2007-11-16
US20040171679A1 (en) 2004-09-02
US20090005442A1 (en) 2009-01-01
CZ301203B6 (cs) 2009-12-09
JP2004523555A (ja) 2004-08-05
NO20033798L (no) 2003-09-26
HUP0303264A2 (hu) 2004-01-28
PT1383489E (pt) 2007-06-21
RU2300373C2 (ru) 2007-06-10
JP4276840B2 (ja) 2009-06-10
RS51055B (sr) 2010-10-31
BR0207645A (pt) 2004-12-28
MXPA03007718A (es) 2004-11-12
CN1235579C (zh) 2006-01-11
TWI312679B (en) 2009-08-01
WO2002067925A1 (en) 2002-09-06
DK1383489T3 (da) 2007-08-06
NO20033798D0 (no) 2003-08-26
US20020165273A1 (en) 2002-11-07
ATE361745T1 (de) 2007-06-15
CN1503667A (zh) 2004-06-09
PL364680A1 (en) 2004-12-13
EP1383489A1 (en) 2004-01-28
IL157591A0 (en) 2004-03-28
DE60220043T2 (de) 2008-01-10
HK1060516A1 (en) 2004-08-13
CA2439295C (en) 2010-05-25
NZ527990A (en) 2006-01-27
RU2003128982A (ru) 2005-03-10
HUP0303264A3 (en) 2012-07-30
IL157591A (en) 2009-12-24
AR035756A1 (es) 2004-07-07
CY1106753T1 (el) 2012-05-23
CZ20032313A3 (cs) 2004-08-18
RS67403A (sr) 2006-12-15
DE60220043D1 (de) 2007-06-21
MY138156A (en) 2009-04-30
HK1065486A1 (en) 2005-02-25
CA2439295A1 (en) 2002-09-06
KR20030076714A (ko) 2003-09-26

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