ATE361745T1 - Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen - Google Patents

Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen

Info

Publication number
ATE361745T1
ATE361745T1 AT02714977T AT02714977T ATE361745T1 AT E361745 T1 ATE361745 T1 AT E361745T1 AT 02714977 T AT02714977 T AT 02714977T AT 02714977 T AT02714977 T AT 02714977T AT E361745 T1 ATE361745 T1 AT E361745T1
Authority
AT
Austria
Prior art keywords
carbamat
compounds
preventing
neurodegenerative disorders
treating neurodegenerative
Prior art date
Application number
AT02714977T
Other languages
English (en)
Inventor
Carlos R Plata-Salaman
Boyu Zhao
Roy E Twyman
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of ATE361745T1 publication Critical patent/ATE361745T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02714977T 2001-02-27 2002-02-21 Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen ATE361745T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27168201P 2001-02-27 2001-02-27
US10/081,764 US20020165273A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating neurodegenerative disorders

Publications (1)

Publication Number Publication Date
ATE361745T1 true ATE361745T1 (de) 2007-06-15

Family

ID=26765943

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02714977T ATE361745T1 (de) 2001-02-27 2002-02-21 Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen

Country Status (27)

Country Link
US (3) US20020165273A1 (de)
EP (1) EP1383489B1 (de)
JP (1) JP4276840B2 (de)
KR (1) KR100910928B1 (de)
CN (1) CN1235579C (de)
AR (1) AR035756A1 (de)
AT (1) ATE361745T1 (de)
BR (1) BR0207645A (de)
CA (1) CA2439295C (de)
CY (1) CY1106753T1 (de)
CZ (1) CZ301203B6 (de)
DE (1) DE60220043T2 (de)
DK (1) DK1383489T3 (de)
ES (1) ES2284845T3 (de)
HK (2) HK1060516A1 (de)
HU (1) HUP0303264A3 (de)
IL (2) IL157591A0 (de)
MX (1) MXPA03007718A (de)
MY (1) MY138156A (de)
NO (1) NO20033798L (de)
NZ (1) NZ527990A (de)
PL (1) PL364680A1 (de)
PT (1) PT1383489E (de)
RS (1) RS51055B (de)
RU (1) RU2300373C2 (de)
TW (1) TWI312679B (de)
WO (1) WO2002067925A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005033093A1 (en) * 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
RS51269B (sr) * 2004-09-16 2010-12-31 Janssen Pharmaceutica N.V. Upotreba 2-fenil-1,2-etandiol-(di)karbamata za tretiranje epileptogeneze
KR20110049901A (ko) * 2004-10-15 2011-05-12 얀센 파마슈티카 엔.브이. 신경변성 질환 치료에 사용하는 카바메이트 화합물
US20070021500A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods for neuroprotection
KR101199499B1 (ko) * 2005-07-26 2012-11-09 얀센 파마슈티카 엔.브이. 물질 관련 장애를 치료하는 방법
EA200970355A1 (ru) * 2006-10-06 2009-12-30 Янссен Фармацевтика Нв Новый кристалл (s)-(+)-2-(2-хлорфенил)-2-гидроксиэтилкарбамата
CN101568362A (zh) * 2006-10-30 2009-10-28 詹森药业有限公司 治疗抑郁症的方法
EP2089011A1 (de) * 2006-10-31 2009-08-19 Janssen Pharmaceutica N.V. Behandlung pervasiver entwicklungsstörungen
CA2803825C (en) * 2010-07-02 2015-12-29 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
US9018253B2 (en) 2010-07-02 2015-04-28 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
US20130060024A1 (en) * 2011-09-07 2013-03-07 Satori Pharmaceuticals, Inc. Compounds useful for treating neurodegenerative disorders
JP6298766B2 (ja) * 2011-12-27 2018-03-20 バイオ−ファーム ソリューションズ カンパニー リミテッド てんかんの予防または治療に使用するためのフェニルカルバメート化合物
KR101717872B1 (ko) * 2013-03-12 2017-03-17 (주)바이오팜솔루션즈 소아 간질 및 간질-관련 증후군의 예방 또는 치료용 페닐카바메이트 화합물
JP6096329B2 (ja) * 2013-03-12 2017-03-15 バイオ−ファーム ソリューションズ カンパニー リミテッド フェニルカルバメート化合物及び記憶損失−関連疾患の予防又は治療用組成物
WO2017150903A1 (en) 2016-02-29 2017-09-08 Bio-Pharm Solutions Co., Ltd. Sulfamate derivative compounds, processes for preparing them and their uses
US11147798B2 (en) 2016-12-14 2021-10-19 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for prevention, alleviation, or treatment of demyelinating disease
CA3112166A1 (en) * 2018-09-21 2020-03-26 Sk Biopharmaceuticals Co., Ltd. Carbamate compound and use of formulation comprising same in preventing, alleviating, or treating acute stress disorder or post-traumatic stress disorder
WO2022045824A1 (en) * 2020-08-31 2022-03-03 Bio-Pharm Solutions Co., Ltd. Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease
CN116234798A (zh) 2020-09-10 2023-06-06 生物药品解决方案有限公司 用于治疗或缓解精神疾病的氨基磺酸酯衍生物化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5474990A (en) * 1989-10-20 1995-12-12 Olney; John W. Barbiturates as safening agents in conjunction with NMDA antagonists
US5492930A (en) * 1994-04-25 1996-02-20 Schering Corporation Method and formulation for treating CNS disorders
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US5728728A (en) * 1996-04-10 1998-03-17 Kozachuk; Walter E. Methods of providing neuroprotection
US6232434B1 (en) * 1996-08-02 2001-05-15 Duke University Medical Center Polymers for delivering nitric oxide in vivo
HUP0303342A3 (en) * 2001-02-27 2012-07-30 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing and treating psychotic disorders
KR100946944B1 (ko) * 2001-02-27 2010-03-15 오르토-맥네일 파마슈티칼, 인코퍼레이티드 양극성 장애의 예방 또는 치료용 카바메이트 화합물
CZ20032299A3 (cs) * 2001-02-27 2004-08-18 Ortho@Mcneilápharmaceuticalźáinc Léčivo pro prevenci nebo léčbu motorických poruch

Also Published As

Publication number Publication date
KR100910928B1 (ko) 2009-08-06
IL157591A (en) 2009-12-24
DE60220043D1 (de) 2007-06-21
CZ301203B6 (cs) 2009-12-09
KR20030076714A (ko) 2003-09-26
AR035756A1 (es) 2004-07-07
CY1106753T1 (el) 2012-05-23
BR0207645A (pt) 2004-12-28
PL364680A1 (en) 2004-12-13
EP1383489B1 (de) 2007-05-09
RU2300373C2 (ru) 2007-06-10
DK1383489T3 (da) 2007-08-06
CZ20032313A3 (cs) 2004-08-18
NO20033798L (no) 2003-09-26
DE60220043T2 (de) 2008-01-10
RS67403A (en) 2006-12-15
RS51055B (sr) 2010-10-31
ES2284845T3 (es) 2007-11-16
HUP0303264A2 (hu) 2004-01-28
CA2439295A1 (en) 2002-09-06
HK1065486A1 (en) 2005-02-25
HK1060516A1 (en) 2004-08-13
IL157591A0 (en) 2004-03-28
TWI312679B (en) 2009-08-01
NZ527990A (en) 2006-01-27
JP4276840B2 (ja) 2009-06-10
CN1235579C (zh) 2006-01-11
HUP0303264A3 (en) 2012-07-30
WO2002067925A1 (en) 2002-09-06
US20040171679A1 (en) 2004-09-02
MY138156A (en) 2009-04-30
US20090005442A1 (en) 2009-01-01
EP1383489A1 (de) 2004-01-28
NO20033798D0 (no) 2003-08-26
CN1503667A (zh) 2004-06-09
US20020165273A1 (en) 2002-11-07
PT1383489E (pt) 2007-06-21
JP2004523555A (ja) 2004-08-05
RU2003128982A (ru) 2005-03-10
MXPA03007718A (es) 2004-11-12
CA2439295C (en) 2010-05-25

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