RU2268880C2 - Кристаллическая форма (s)-2-этокси-3-[4-(2-{4-метансульфонилоксифенил}этокси)фенил]пропановой кислоты - Google Patents

Кристаллическая форма (s)-2-этокси-3-[4-(2-{4-метансульфонилоксифенил}этокси)фенил]пропановой кислоты Download PDF

Info

Publication number
RU2268880C2
RU2268880C2 RU2002113450/04A RU2002113450A RU2268880C2 RU 2268880 C2 RU2268880 C2 RU 2268880C2 RU 2002113450/04 A RU2002113450/04 A RU 2002113450/04A RU 2002113450 A RU2002113450 A RU 2002113450A RU 2268880 C2 RU2268880 C2 RU 2268880C2
Authority
RU
Russia
Prior art keywords
ethoxy
compound
crystalline form
solution
formula
Prior art date
Application number
RU2002113450/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2002113450A (ru
Inventor
Мари БОЙЕ (SE)
Мария БОЙЕ
Кароль ХОРВАТ (SE)
Кароль ХОРВАТ
Торд ИНГХАРДТ (SE)
Торд ИНГХАРДТ
Original Assignee
Астразенека Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9904416A external-priority patent/SE9904416D0/xx
Priority claimed from SE0001187A external-priority patent/SE0001187D0/xx
Application filed by Астразенека Аб filed Critical Астразенека Аб
Publication of RU2002113450A publication Critical patent/RU2002113450A/ru
Application granted granted Critical
Publication of RU2268880C2 publication Critical patent/RU2268880C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
RU2002113450/04A 1999-12-03 2000-11-29 Кристаллическая форма (s)-2-этокси-3-[4-(2-{4-метансульфонилоксифенил}этокси)фенил]пропановой кислоты RU2268880C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9904416-6 1999-12-03
SE9904416A SE9904416D0 (sv) 1999-12-03 1999-12-03 Crystalline form
SE0001187A SE0001187D0 (sv) 2000-04-03 2000-04-03 Crystalline form
SE0001187-4 2000-04-03

Publications (2)

Publication Number Publication Date
RU2002113450A RU2002113450A (ru) 2004-01-10
RU2268880C2 true RU2268880C2 (ru) 2006-01-27

Family

ID=26655058

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002113450/04A RU2268880C2 (ru) 1999-12-03 2000-11-29 Кристаллическая форма (s)-2-этокси-3-[4-(2-{4-метансульфонилоксифенил}этокси)фенил]пропановой кислоты

Country Status (30)

Country Link
US (1) US6531622B1 (de)
EP (1) EP1237855B1 (de)
JP (1) JP2003515582A (de)
KR (1) KR20030029040A (de)
CN (1) CN1198799C (de)
AR (1) AR029412A1 (de)
AT (1) ATE261431T1 (de)
AU (1) AU773777B2 (de)
BR (1) BR0016131A (de)
CA (1) CA2392038A1 (de)
CO (1) CO5271735A1 (de)
CZ (1) CZ20021902A3 (de)
DE (1) DE60008921T2 (de)
DK (1) DK1237855T3 (de)
EE (1) EE200200278A (de)
ES (1) ES2215769T3 (de)
HK (1) HK1048980A1 (de)
HU (1) HUP0203444A3 (de)
IL (1) IL149577A0 (de)
IS (1) IS6400A (de)
MX (1) MXPA02005327A (de)
MY (1) MY135954A (de)
NO (1) NO20022598L (de)
NZ (1) NZ518925A (de)
PL (1) PL357118A1 (de)
PT (1) PT1237855E (de)
RU (1) RU2268880C2 (de)
SK (1) SK7652002A3 (de)
TR (1) TR200401333T4 (de)
WO (1) WO2001040171A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9812772A (pt) 1997-10-27 2000-10-10 Reddy Research Foundation "compostos tricìclicos inéditos e o seu emprego na medicina;processo para a sua preparação e composições farmacêuticas contendo os mesmos"
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
CN1280574A (zh) 1997-10-27 2001-01-17 雷迪研究基金会 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物
RU2247722C2 (ru) 1997-10-27 2005-03-10 Др. Редди`З Лабораториз Лимитед Производные арилкарбоновых кислот, способы их получения, фармацевтическая композиция на их основе, способы лечения и предупреждения различных заболеваний, промежуточные соединения и способы их получения
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
WO2000026200A1 (en) 1998-10-29 2000-05-11 Dr. Reddy's Research Foundation An improved process for the preparation of new antidiabetic agents
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
US7084177B2 (en) * 1999-12-03 2006-08-01 Astrazeneca Ab Comminuted form of(S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl}ethoxy)phenyl] propanoic acid
US6897199B2 (en) 2001-02-05 2005-05-24 Dr. Reddy's Laboratories Ltd. Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds
DE10308355A1 (de) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10308353A1 (de) 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308351A1 (de) 2003-02-27 2004-11-25 Aventis Pharma Deutschland Gmbh 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7148246B2 (en) 2003-02-27 2006-12-12 Sanofi-Aventis Deutschland Gmbh Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
DE10308352A1 (de) 2003-02-27 2004-09-09 Aventis Pharma Deutschland Gmbh Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
WO2005051298A2 (en) 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
EP1586573B1 (de) 2004-04-01 2007-02-07 Sanofi-Aventis Deutschland GmbH Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
DE102004035034A1 (de) * 2004-07-20 2006-02-16 Degussa Ag Racematspaltung von p-Hydroxyphenyl-2-alkoxy-propionsäuren
DE102005026762A1 (de) 2005-06-09 2006-12-21 Sanofi-Aventis Deutschland Gmbh Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801990D0 (sv) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
SE9801992D0 (sv) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
MA26634A1 (fr) * 1998-06-04 2004-12-20 Astra Ab Nouveaux derives de l'acide 3-aryl propionique et analogues

Also Published As

Publication number Publication date
DE60008921T2 (de) 2005-01-20
ATE261431T1 (de) 2004-03-15
TR200401333T4 (tr) 2004-08-23
RU2002113450A (ru) 2004-01-10
AU773777B2 (en) 2004-06-03
IL149577A0 (en) 2002-11-10
CN1409701A (zh) 2003-04-09
BR0016131A (pt) 2002-08-20
EE200200278A (et) 2003-06-16
MXPA02005327A (es) 2002-12-06
EP1237855B1 (de) 2004-03-10
SK7652002A3 (en) 2002-11-06
PT1237855E (pt) 2004-06-30
WO2001040171A1 (en) 2001-06-07
MY135954A (en) 2008-07-31
US6531622B1 (en) 2003-03-11
AU2035001A (en) 2001-06-12
PL357118A1 (en) 2004-07-12
DE60008921D1 (en) 2004-04-15
NZ518925A (en) 2004-06-25
HUP0203444A3 (en) 2003-05-28
ES2215769T3 (es) 2004-10-16
AR029412A1 (es) 2003-06-25
CZ20021902A3 (cs) 2002-11-13
HK1048980A1 (en) 2003-04-25
NO20022598D0 (no) 2002-05-31
EP1237855A1 (de) 2002-09-11
CA2392038A1 (en) 2001-06-07
DK1237855T3 (da) 2004-06-14
CO5271735A1 (es) 2003-04-30
JP2003515582A (ja) 2003-05-07
HUP0203444A2 (hu) 2003-02-28
KR20030029040A (ko) 2003-04-11
IS6400A (is) 2002-05-28
CN1198799C (zh) 2005-04-27
NO20022598L (no) 2002-05-31

Similar Documents

Publication Publication Date Title
RU2268880C2 (ru) Кристаллическая форма (s)-2-этокси-3-[4-(2-{4-метансульфонилоксифенил}этокси)фенил]пропановой кислоты
JP3493341B2 (ja) ＥｔＯ２Ｃ−ＣＨ２−（Ｒ）Ｃｇｌ−Ａｚｅ−Ｐａｂ−ＯＨの結晶形
TWI718104B (zh) AHU-377結晶型游離酸、半鈣鹽、α-苯乙胺鹽及其製備方法和應用
UA73974C2 (en) Hydrochloride 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, a process of preparing thereof and a pharmaceutical composition based thereon
SI9720038A (sl) Polimorfi donepezil hidroklorida in postopek izdelave
RU2248966C2 (ru) Измельченная форма (s)-2-этокси-3-[4-(2-{4-метансульфонилоксифенил}этокси)фенил]пропановой кислоты
US11787828B2 (en) Crystalline forms and methods of producing crystalline forms of a compound
ZA200510199B (en) Pharmaceutically useful salts of carboxylic acid derivatives
KR102442536B1 (ko) 리나글립틴 결정형 및 이의 제조방법
KR100419404B1 (ko) 공지된 브라디키닌 길항제의 유리질 형태
WO2001040165A1 (en) Crystalline form of 3-{4-[2-(4-tert-butoxycarbonylaminophenyl)ethoxy]phenyl}-(s)-2-ethoxy propanoic acid
BR112020010803A2 (pt) sal, (r)-3-(1-(2,3-dicloro-4-(pirazin-2-il)fenil)-2,2,2-trifluoroetil)-1-metil-1-(1-metilpiperidin-4-il) uréia cristalino, produto de medicamento, composição, método para preparar o sal e usos do sal
US7649008B2 (en) Crystal of benzimidazole derivative and process for producing the same
ZA200203706B (en) Crystalline form of (S)-2ethoxy-3-[4-(2-4-methanesulfonyloxyphenyl} ethoxy)phenyl] propanoic acid.
US20240043459A1 (en) Crystalline forms and methods of producing crystalline forms of a compound
US20230382921A1 (en) Amorphous Form of Isoquinoline Derivative
US20220380288A1 (en) Solid state forms of fezagepras and process for preparation thereof
WO2021211938A1 (en) Solid forms of inhibitors of plasma kallikrein
JP2010518011A (ja) 化学化合物、医薬組成物および方法

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20061130