DK1237855T3 - Krystallinsk form af (S)-2-ethoxy-3-[4-(2-(4-methansulfonyloxyphenyl)ethoxy)phenyl]propansyre - Google Patents

Krystallinsk form af (S)-2-ethoxy-3-[4-(2-(4-methansulfonyloxyphenyl)ethoxy)phenyl]propansyre

Info

Publication number
DK1237855T3
DK1237855T3 DK00983618T DK00983618T DK1237855T3 DK 1237855 T3 DK1237855 T3 DK 1237855T3 DK 00983618 T DK00983618 T DK 00983618T DK 00983618 T DK00983618 T DK 00983618T DK 1237855 T3 DK1237855 T3 DK 1237855T3
Authority
DK
Denmark
Prior art keywords
ethoxy
methanesulfonyloxyphenyl
phenyl
crystalline form
propanoic acid
Prior art date
Application number
DK00983618T
Other languages
Danish (da)
English (en)
Inventor
Maria Boije
Karol Horvath
Tord Inghardt
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9904416A external-priority patent/SE9904416D0/xx
Priority claimed from SE0001187A external-priority patent/SE0001187D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1237855T3 publication Critical patent/DK1237855T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66Methanesulfonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
DK00983618T 1999-12-03 2000-11-29 Krystallinsk form af (S)-2-ethoxy-3-[4-(2-(4-methansulfonyloxyphenyl)ethoxy)phenyl]propansyre DK1237855T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9904416A SE9904416D0 (sv) 1999-12-03 1999-12-03 Crystalline form
SE0001187A SE0001187D0 (sv) 2000-04-03 2000-04-03 Crystalline form
PCT/SE2000/002384 WO2001040171A1 (en) 1999-12-03 2000-11-29 Crystalline form of (s)-2 ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl} ethoxy) phenyl] propanoic acid

Publications (1)

Publication Number Publication Date
DK1237855T3 true DK1237855T3 (da) 2004-06-14

Family

ID=26655058

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00983618T DK1237855T3 (da) 1999-12-03 2000-11-29 Krystallinsk form af (S)-2-ethoxy-3-[4-(2-(4-methansulfonyloxyphenyl)ethoxy)phenyl]propansyre

Country Status (30)

Country Link
US (1) US6531622B1 (de)
EP (1) EP1237855B1 (de)
JP (1) JP2003515582A (de)
KR (1) KR20030029040A (de)
CN (1) CN1198799C (de)
AR (1) AR029412A1 (de)
AT (1) ATE261431T1 (de)
AU (1) AU773777B2 (de)
BR (1) BR0016131A (de)
CA (1) CA2392038A1 (de)
CO (1) CO5271735A1 (de)
CZ (1) CZ20021902A3 (de)
DE (1) DE60008921T2 (de)
DK (1) DK1237855T3 (de)
EE (1) EE200200278A (de)
ES (1) ES2215769T3 (de)
HK (1) HK1048980A1 (de)
HU (1) HUP0203444A3 (de)
IL (1) IL149577A0 (de)
IS (1) IS6400A (de)
MX (1) MXPA02005327A (de)
MY (1) MY135954A (de)
NO (1) NO20022598L (de)
NZ (1) NZ518925A (de)
PL (1) PL357118A1 (de)
PT (1) PT1237855E (de)
RU (1) RU2268880C2 (de)
SK (1) SK7652002A3 (de)
TR (1) TR200401333T4 (de)
WO (1) WO2001040171A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9812772A (pt) 1997-10-27 2000-10-10 Reddy Research Foundation "compostos tricìclicos inéditos e o seu emprego na medicina;processo para a sua preparação e composições farmacêuticas contendo os mesmos"
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
CN1280574A (zh) 1997-10-27 2001-01-17 雷迪研究基金会 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物
RU2247722C2 (ru) 1997-10-27 2005-03-10 Др. Редди`З Лабораториз Лимитед Производные арилкарбоновых кислот, способы их получения, фармацевтическая композиция на их основе, способы лечения и предупреждения различных заболеваний, промежуточные соединения и способы их получения
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
WO2000026200A1 (en) 1998-10-29 2000-05-11 Dr. Reddy's Research Foundation An improved process for the preparation of new antidiabetic agents
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
US7084177B2 (en) * 1999-12-03 2006-08-01 Astrazeneca Ab Comminuted form of(S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl}ethoxy)phenyl] propanoic acid
US6897199B2 (en) 2001-02-05 2005-05-24 Dr. Reddy's Laboratories Ltd. Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds
DE10308355A1 (de) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10308353A1 (de) 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308351A1 (de) 2003-02-27 2004-11-25 Aventis Pharma Deutschland Gmbh 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7148246B2 (en) 2003-02-27 2006-12-12 Sanofi-Aventis Deutschland Gmbh Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
DE10308352A1 (de) 2003-02-27 2004-09-09 Aventis Pharma Deutschland Gmbh Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
WO2005051298A2 (en) 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
EP1586573B1 (de) 2004-04-01 2007-02-07 Sanofi-Aventis Deutschland GmbH Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika
DE102004035034A1 (de) * 2004-07-20 2006-02-16 Degussa Ag Racematspaltung von p-Hydroxyphenyl-2-alkoxy-propionsäuren
DE102005026762A1 (de) 2005-06-09 2006-12-21 Sanofi-Aventis Deutschland Gmbh Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801990D0 (sv) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
SE9801992D0 (sv) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
MA26634A1 (fr) * 1998-06-04 2004-12-20 Astra Ab Nouveaux derives de l'acide 3-aryl propionique et analogues

Also Published As

Publication number Publication date
DE60008921T2 (de) 2005-01-20
ATE261431T1 (de) 2004-03-15
TR200401333T4 (tr) 2004-08-23
RU2002113450A (ru) 2004-01-10
AU773777B2 (en) 2004-06-03
IL149577A0 (en) 2002-11-10
CN1409701A (zh) 2003-04-09
BR0016131A (pt) 2002-08-20
EE200200278A (et) 2003-06-16
MXPA02005327A (es) 2002-12-06
EP1237855B1 (de) 2004-03-10
SK7652002A3 (en) 2002-11-06
PT1237855E (pt) 2004-06-30
WO2001040171A1 (en) 2001-06-07
MY135954A (en) 2008-07-31
US6531622B1 (en) 2003-03-11
AU2035001A (en) 2001-06-12
PL357118A1 (en) 2004-07-12
DE60008921D1 (en) 2004-04-15
NZ518925A (en) 2004-06-25
HUP0203444A3 (en) 2003-05-28
ES2215769T3 (es) 2004-10-16
AR029412A1 (es) 2003-06-25
CZ20021902A3 (cs) 2002-11-13
HK1048980A1 (en) 2003-04-25
NO20022598D0 (no) 2002-05-31
RU2268880C2 (ru) 2006-01-27
EP1237855A1 (de) 2002-09-11
CA2392038A1 (en) 2001-06-07
CO5271735A1 (es) 2003-04-30
JP2003515582A (ja) 2003-05-07
HUP0203444A2 (hu) 2003-02-28
KR20030029040A (ko) 2003-04-11
IS6400A (is) 2002-05-28
CN1198799C (zh) 2005-04-27
NO20022598L (no) 2002-05-31

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