RU2263673C2 - Алкоксизамещенные бензимидазольные соединения, содержащие их фармацевтические препараты и способ их применения - Google Patents

Алкоксизамещенные бензимидазольные соединения, содержащие их фармацевтические препараты и способ их применения Download PDF

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Publication number
RU2263673C2
RU2263673C2 RU2002107421/04A RU2002107421A RU2263673C2 RU 2263673 C2 RU2263673 C2 RU 2263673C2 RU 2002107421/04 A RU2002107421/04 A RU 2002107421/04A RU 2002107421 A RU2002107421 A RU 2002107421A RU 2263673 C2 RU2263673 C2 RU 2263673C2
Authority
RU
Russia
Prior art keywords
methoxy
benzimidazole
methyl
pyridinyl
sulfinyl
Prior art date
Application number
RU2002107421/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2002107421A (ru
Inventor
Роберт Р. УИТТЛ (US)
Роберт Р. УИТТЛ
Фредерик Д. САНЧИЛИО (US)
Фредерик Д. САНЧИЛИО
Грэйсон Уокер СТОУЭЛЛ (US)
Грэйсон Уокер СТОУЭЛЛ
Дуглас Джон ДЖЕНКИНС (US)
Дуглас Джон ДЖЕНКИНС
Линда УИТТОЛ (US)
Линда УИТТОЛ
Гленн Алан МЕЙЕР (US)
Гленн Алан МЕЙЕР
Стивен А. ФОНТАНА (US)
Стивен А. Фонтана
Original Assignee
ааиФАРМА ИНК.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/519,976 external-priority patent/US6262085B1/en
Application filed by ааиФАРМА ИНК. filed Critical ааиФАРМА ИНК.
Publication of RU2002107421A publication Critical patent/RU2002107421A/ru
Application granted granted Critical
Publication of RU2263673C2 publication Critical patent/RU2263673C2/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2002107421/04A 1999-08-26 2000-08-25 Алкоксизамещенные бензимидазольные соединения, содержащие их фармацевтические препараты и способ их применения RU2263673C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15087899P 1999-08-26 1999-08-26
US60/150,878 1999-08-26
US09/519,976 2000-03-07
US09/519,976 US6262085B1 (en) 1999-08-26 2000-03-07 Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same

Publications (2)

Publication Number Publication Date
RU2002107421A RU2002107421A (ru) 2003-10-10
RU2263673C2 true RU2263673C2 (ru) 2005-11-10

Family

ID=26848119

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002107421/04A RU2263673C2 (ru) 1999-08-26 2000-08-25 Алкоксизамещенные бензимидазольные соединения, содержащие их фармацевтические препараты и способ их применения

Country Status (16)

Country Link
EP (1) EP1206466B1 (enExample)
JP (1) JP4312405B2 (enExample)
KR (1) KR100712039B1 (enExample)
CN (2) CN1183127C (enExample)
AT (1) ATE306483T1 (enExample)
AU (2) AU777667B2 (enExample)
BR (1) BR0014145A (enExample)
CA (1) CA2382867A1 (enExample)
DE (1) DE60023154T2 (enExample)
HR (1) HRP20020174A2 (enExample)
MX (1) MXPA02002007A (enExample)
NO (1) NO326849B1 (enExample)
RO (1) RO122491B1 (enExample)
RU (1) RU2263673C2 (enExample)
SI (1) SI20974A (enExample)
SK (1) SK286903B6 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2376231A (en) * 2001-06-06 2002-12-11 Cipla Ltd Benzimidazole-cyclodextrin inclusion complex
JP5457632B2 (ja) * 2004-06-24 2014-04-02 アストラゼネカ・アクチエボラーグ エソメプラゾールのナトリウム塩の製造に使用するための結晶の改変型の作成方法
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
CN103524491A (zh) * 2013-10-16 2014-01-22 江南大学 埃索美拉唑镁盐四水合物的三种晶型及其制备方法
US12366506B2 (en) * 2020-03-09 2025-07-22 Idexx Laboratories, Inc. Method for removing interfering components of a liquid sample prior to dispensing same on a chemical reagent test slide
CN114558004B (zh) * 2022-03-29 2023-08-11 奎马特里克斯有限公司 Qtx125药物制剂
CN116082247B (zh) * 2023-01-19 2025-08-01 浙江工业大学 一种苯并咪唑类衍生物及其应用
CN118225938B (zh) * 2024-04-02 2024-08-30 江苏海洋大学 一种中药复方五神汤的质量检测方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US895292A (en) * 1904-07-22 1908-08-04 Marvin A Neeland Blowing-engine inlet-valve.
SU795476A3 (ru) * 1974-02-18 1981-01-07 Аб Хессле (Фирма) Способ получени производныхбЕНзиМидАзОлА или иХ СОлЕй
US5039806A (en) * 1983-02-11 1991-08-13 Ab Hassle Novel pharmacologically active compound pyridyl methylsulfinyl benzimidazole
US5693818A (en) * 1993-05-28 1997-12-02 Astra Aktiebolag Process for preparing pure salts of pyridinylmethyl-sulfinyl-1H-benzimidazole

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US895292A (en) * 1904-07-22 1908-08-04 Marvin A Neeland Blowing-engine inlet-valve.
SU795476A3 (ru) * 1974-02-18 1981-01-07 Аб Хессле (Фирма) Способ получени производныхбЕНзиМидАзОлА или иХ СОлЕй
US5039806A (en) * 1983-02-11 1991-08-13 Ab Hassle Novel pharmacologically active compound pyridyl methylsulfinyl benzimidazole
US5693818A (en) * 1993-05-28 1997-12-02 Astra Aktiebolag Process for preparing pure salts of pyridinylmethyl-sulfinyl-1H-benzimidazole

Also Published As

Publication number Publication date
DE60023154D1 (de) 2006-02-23
SK286903B6 (sk) 2009-07-06
NO20020914D0 (no) 2002-02-25
AU2005200203B2 (en) 2008-01-10
SI20974A (sl) 2003-02-28
MXPA02002007A (es) 2003-08-20
AU2005200203A1 (en) 2005-02-10
CA2382867A1 (en) 2001-03-01
JP2003507475A (ja) 2003-02-25
KR20020035861A (ko) 2002-05-15
HRP20020174A2 (en) 2005-12-31
DE60023154T2 (de) 2006-06-22
SK2812002A3 (en) 2002-07-02
AU777667B2 (en) 2004-10-28
NO326849B1 (no) 2009-03-02
CN1384831A (zh) 2002-12-11
CN1636564A (zh) 2005-07-13
EP1206466A1 (en) 2002-05-22
KR100712039B1 (ko) 2007-04-27
JP4312405B2 (ja) 2009-08-12
AU7073700A (en) 2001-03-19
CN1183127C (zh) 2005-01-05
ATE306483T1 (de) 2005-10-15
NO20020914L (no) 2002-04-26
RO122491B1 (ro) 2009-07-30
BR0014145A (pt) 2002-05-14
EP1206466B1 (en) 2005-10-12

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Legal Events

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20100826