CN1183127C - 烷氧基取代的苯并咪唑化合物,含有它们的药物制剂及使用它们的方法 - Google Patents

烷氧基取代的苯并咪唑化合物,含有它们的药物制剂及使用它们的方法 Download PDF

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Publication number
CN1183127C
CN1183127C CNB008149232A CN00814923A CN1183127C CN 1183127 C CN1183127 C CN 1183127C CN B008149232 A CNB008149232 A CN B008149232A CN 00814923 A CN00814923 A CN 00814923A CN 1183127 C CN1183127 C CN 1183127C
Authority
CN
China
Prior art keywords
methoxy
formula
compound
methyl
pyridyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB008149232A
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English (en)
Chinese (zh)
Other versions
CN1384831A (zh
Inventor
R��R������
R·R·怀特勒
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F·D·桑茨利奥
ά
G·W·斯托维尔
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D·J·詹金斯
L·怀塔尔
��÷Ү��
G·A·梅耶
S·A·丰塔纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AAIPharma Inc
Original Assignee
Applied Analytical Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/519,976 external-priority patent/US6262085B1/en
Application filed by Applied Analytical Industries Inc filed Critical Applied Analytical Industries Inc
Publication of CN1384831A publication Critical patent/CN1384831A/zh
Application granted granted Critical
Publication of CN1183127C publication Critical patent/CN1183127C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNB008149232A 1999-08-26 2000-08-25 烷氧基取代的苯并咪唑化合物,含有它们的药物制剂及使用它们的方法 Expired - Fee Related CN1183127C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15087899P 1999-08-26 1999-08-26
US60/150,878 1999-08-26
US09/519,976 2000-03-07
US09/519,976 US6262085B1 (en) 1999-08-26 2000-03-07 Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2004100946486A Division CN1636564A (zh) 1999-08-26 2000-08-25 含烷氧基取代苯并咪唑化合物的组合物和药物制剂及其制法

Publications (2)

Publication Number Publication Date
CN1384831A CN1384831A (zh) 2002-12-11
CN1183127C true CN1183127C (zh) 2005-01-05

Family

ID=26848119

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB008149232A Expired - Fee Related CN1183127C (zh) 1999-08-26 2000-08-25 烷氧基取代的苯并咪唑化合物,含有它们的药物制剂及使用它们的方法
CNA2004100946486A Pending CN1636564A (zh) 1999-08-26 2000-08-25 含烷氧基取代苯并咪唑化合物的组合物和药物制剂及其制法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2004100946486A Pending CN1636564A (zh) 1999-08-26 2000-08-25 含烷氧基取代苯并咪唑化合物的组合物和药物制剂及其制法

Country Status (16)

Country Link
EP (1) EP1206466B1 (enExample)
JP (1) JP4312405B2 (enExample)
KR (1) KR100712039B1 (enExample)
CN (2) CN1183127C (enExample)
AT (1) ATE306483T1 (enExample)
AU (2) AU777667B2 (enExample)
BR (1) BR0014145A (enExample)
CA (1) CA2382867A1 (enExample)
DE (1) DE60023154T2 (enExample)
HR (1) HRP20020174A2 (enExample)
MX (1) MXPA02002007A (enExample)
NO (1) NO326849B1 (enExample)
RO (1) RO122491B1 (enExample)
RU (1) RU2263673C2 (enExample)
SI (1) SI20974A (enExample)
SK (1) SK286903B6 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2376231A (en) * 2001-06-06 2002-12-11 Cipla Ltd Benzimidazole-cyclodextrin inclusion complex
JP5457632B2 (ja) * 2004-06-24 2014-04-02 アストラゼネカ・アクチエボラーグ エソメプラゾールのナトリウム塩の製造に使用するための結晶の改変型の作成方法
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
CN103524491A (zh) * 2013-10-16 2014-01-22 江南大学 埃索美拉唑镁盐四水合物的三种晶型及其制备方法
US12366506B2 (en) * 2020-03-09 2025-07-22 Idexx Laboratories, Inc. Method for removing interfering components of a liquid sample prior to dispensing same on a chemical reagent test slide
CN114558004B (zh) * 2022-03-29 2023-08-11 奎马特里克斯有限公司 Qtx125药物制剂
CN116082247B (zh) * 2023-01-19 2025-08-01 浙江工业大学 一种苯并咪唑类衍生物及其应用
CN118225938B (zh) * 2024-04-02 2024-08-30 江苏海洋大学 一种中药复方五神汤的质量检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US895292A (en) * 1904-07-22 1908-08-04 Marvin A Neeland Blowing-engine inlet-valve.
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds

Also Published As

Publication number Publication date
RU2263673C2 (ru) 2005-11-10
DE60023154D1 (de) 2006-02-23
SK286903B6 (sk) 2009-07-06
NO20020914D0 (no) 2002-02-25
AU2005200203B2 (en) 2008-01-10
SI20974A (sl) 2003-02-28
MXPA02002007A (es) 2003-08-20
AU2005200203A1 (en) 2005-02-10
CA2382867A1 (en) 2001-03-01
JP2003507475A (ja) 2003-02-25
KR20020035861A (ko) 2002-05-15
HRP20020174A2 (en) 2005-12-31
DE60023154T2 (de) 2006-06-22
SK2812002A3 (en) 2002-07-02
AU777667B2 (en) 2004-10-28
NO326849B1 (no) 2009-03-02
CN1384831A (zh) 2002-12-11
CN1636564A (zh) 2005-07-13
EP1206466A1 (en) 2002-05-22
KR100712039B1 (ko) 2007-04-27
JP4312405B2 (ja) 2009-08-12
AU7073700A (en) 2001-03-19
ATE306483T1 (de) 2005-10-15
NO20020914L (no) 2002-04-26
RO122491B1 (ro) 2009-07-30
BR0014145A (pt) 2002-05-14
EP1206466B1 (en) 2005-10-12

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C06 Publication
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C10 Entry into substantive examination
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C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050105

Termination date: 20100825