RU2218159C2 - ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ - Google Patents

ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ Download PDF

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RU2218159C2
RU2218159C2 RU99124771/14A RU99124771A RU2218159C2 RU 2218159 C2 RU2218159 C2 RU 2218159C2 RU 99124771/14 A RU99124771/14 A RU 99124771/14A RU 99124771 A RU99124771 A RU 99124771A RU 2218159 C2 RU2218159 C2 RU 2218159C2
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Russia
Prior art keywords
melanin
tyrosine
pgf
methyl
tyrosinase
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RU99124771/14A
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English (en)
Russian (ru)
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RU99124771A (ru
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Филиппо Драго
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Фармациа Энд Апджон Аб
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU99124771/14A 1997-04-22 1998-04-21 ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ RU2218159C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI97A000939 1997-04-22
IT97MI000939A IT1291633B1 (it) 1997-04-22 1997-04-22 Uso dell'alfa-metil-p-tirosina per inibire la produzione di melanina nei melanociti dell'iride

Publications (2)

Publication Number Publication Date
RU99124771A RU99124771A (ru) 2001-09-20
RU2218159C2 true RU2218159C2 (ru) 2003-12-10

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RU99124771/14A RU2218159C2 (ru) 1997-04-22 1998-04-21 ПРИМЕНЕНИЕ α-МЕТИЛ-п-ТИРОЗИНА ДЛЯ ИНГИБИРОВАНИЯ ПРОДУЦИРОВАНИЯ МЕЛАНИНА В МЕЛАНОЦИТАХ РАДУЖНОЙ ОБОЛОЧКИ

Country Status (22)

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US (1) US6359001B1 (enExample)
EP (1) EP0977575B1 (enExample)
JP (1) JP2001521540A (enExample)
KR (1) KR20010020202A (enExample)
CN (1) CN1255064A (enExample)
AT (1) ATE227577T1 (enExample)
AU (1) AU732046B2 (enExample)
CA (1) CA2287887A1 (enExample)
DE (1) DE69809408T2 (enExample)
DK (1) DK0977575T3 (enExample)
ES (1) ES2187028T3 (enExample)
HU (1) HUP0002100A3 (enExample)
IL (1) IL132503A (enExample)
IT (1) IT1291633B1 (enExample)
NO (1) NO995122L (enExample)
NZ (1) NZ500435A (enExample)
PL (1) PL189304B1 (enExample)
PT (1) PT977575E (enExample)
RU (1) RU2218159C2 (enExample)
SI (1) SI0977575T1 (enExample)
SK (1) SK284255B6 (enExample)
WO (1) WO1998047515A1 (enExample)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
CZ20013174A3 (cs) 1999-03-05 2002-02-13 The Procter & Gamble Company C16 nenasycené FP-selektivní prostaglandinové analogy
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
WO2010087983A1 (en) * 2009-01-29 2010-08-05 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US9744237B2 (en) * 2009-01-29 2017-08-29 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US20120076848A1 (en) * 2009-07-22 2012-03-29 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
KR102172658B1 (ko) * 2012-01-17 2020-11-02 타임, 인크. 약학 조성물 및 방법
US10272068B2 (en) 2012-01-17 2019-04-30 Tyme, Inc. Pharmaceutical compositions and methods
US20130183263A1 (en) 2012-01-17 2013-07-18 Steven Hoffman Pharmaceutical compositions and methods
US10646552B2 (en) 2012-01-17 2020-05-12 Tyme, Inc. Pharmaceutical compositions and methods
US8481498B1 (en) 2012-01-17 2013-07-09 Steven Hoffman Pharmaceutical compositions and methods
US9763903B2 (en) 2013-10-22 2017-09-19 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
US9326962B2 (en) 2013-10-22 2016-05-03 Steven Hoffman Compositions and methods for treating intestinal hyperpermeability
US9585841B2 (en) 2013-10-22 2017-03-07 Tyme, Inc. Tyrosine derivatives and compositions comprising them
US10813901B2 (en) 2013-10-22 2020-10-27 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
US10751313B2 (en) 2013-10-22 2020-08-25 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
ES2738248B2 (es) * 2018-06-21 2023-03-10 Consejo Superior Investigacion Uso de inhibidores de la tirosina hidroxilasa para el tratamiento del aneurisma de aorta
WO2020018291A1 (en) 2018-07-19 2020-01-23 Yamo Pharmaceuticals Llc Compositions and methods for treating autism
WO2020232227A1 (en) 2019-05-14 2020-11-19 Tyme, Inc. Compositions and methods for treating cancer
CN116035151A (zh) * 2023-01-18 2023-05-02 云南贝泰妮生物科技集团股份有限公司 一种刺梨闪释粉及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04117313A (ja) * 1990-09-06 1992-04-17 Kanebo Ltd 美白化粧料

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
РЛС. Энциклопедия лекарств. - М., 2000, с.468. *

Also Published As

Publication number Publication date
JP2001521540A (ja) 2001-11-06
IL132503A0 (en) 2001-03-19
IL132503A (en) 2004-06-20
SI0977575T1 (en) 2003-04-30
NO995122D0 (no) 1999-10-21
DK0977575T3 (da) 2003-03-10
CN1255064A (zh) 2000-05-31
US6359001B1 (en) 2002-03-19
SK284255B6 (sk) 2004-12-01
DE69809408D1 (de) 2002-12-19
KR20010020202A (ko) 2001-03-15
IT1291633B1 (it) 1999-01-11
PL336386A1 (en) 2000-06-19
SK142499A3 (en) 2000-09-12
EP0977575B1 (en) 2002-11-13
WO1998047515A1 (en) 1998-10-29
AU732046B2 (en) 2001-04-12
PT977575E (pt) 2003-03-31
HUP0002100A2 (hu) 2000-11-28
HUP0002100A3 (en) 2003-05-28
AU7646298A (en) 1998-11-13
DE69809408T2 (de) 2003-07-10
NO995122L (no) 1999-12-21
ES2187028T3 (es) 2003-05-16
CA2287887A1 (en) 1998-10-29
ITMI970939A1 (it) 1998-10-22
ATE227577T1 (de) 2002-11-15
NZ500435A (en) 2001-09-28
ITMI970939A0 (enExample) 1997-04-22
EP0977575A1 (en) 2000-02-09
PL189304B1 (pl) 2005-07-29

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20060422