RU2123841C1 - Способ получения фармацевтической композиции, фармацевтическая композиция, фармацевтический препарат, способ получения фармацевтического препарата - Google Patents

Способ получения фармацевтической композиции, фармацевтическая композиция, фармацевтический препарат, способ получения фармацевтического препарата Download PDF

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Publication number
RU2123841C1
RU2123841C1 RU94019417/14A RU94019417A RU2123841C1 RU 2123841 C1 RU2123841 C1 RU 2123841C1 RU 94019417/14 A RU94019417/14 A RU 94019417/14A RU 94019417 A RU94019417 A RU 94019417A RU 2123841 C1 RU2123841 C1 RU 2123841C1
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RU
Russia
Prior art keywords
propionic acid
agglomerates
isobutylphenyl
starch
ibuprofen
Prior art date
Application number
RU94019417/14A
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English (en)
Russian (ru)
Other versions
RU94019417A (ru
Inventor
Джон Эткин Грэхем (GB)
Джон Эткин Грэхем
Дрю Питер (GB)
Дрю Питер
Лесли Тернер Джон (GB)
Лесли Тернер Джон
Original Assignee
Дзе Бутс Компани ПЛС
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дзе Бутс Компани ПЛС filed Critical Дзе Бутс Компани ПЛС
Publication of RU94019417A publication Critical patent/RU94019417A/ru
Application granted granted Critical
Publication of RU2123841C1 publication Critical patent/RU2123841C1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU94019417/14A 1991-09-06 1992-08-25 Способ получения фармацевтической композиции, фармацевтическая композиция, фармацевтический препарат, способ получения фармацевтического препарата RU2123841C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9119052.0 1991-09-06
GB919119052A GB9119052D0 (en) 1991-09-06 1991-09-06 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
RU94019417A RU94019417A (ru) 1995-11-10
RU2123841C1 true RU2123841C1 (ru) 1998-12-27

Family

ID=10700981

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94019417/14A RU2123841C1 (ru) 1991-09-06 1992-08-25 Способ получения фармацевтической композиции, фармацевтическая композиция, фармацевтический препарат, способ получения фармацевтического препарата

Country Status (16)

Country Link
US (1) US5512302A (enExample)
EP (1) EP0602112B1 (enExample)
JP (1) JP3444597B2 (enExample)
KR (1) KR100253046B1 (enExample)
AT (1) ATE353213T1 (enExample)
AU (1) AU655673B2 (enExample)
CA (1) CA2116956C (enExample)
CZ (1) CZ282271B6 (enExample)
DE (1) DE69233678T2 (enExample)
FI (1) FI107878B (enExample)
GB (1) GB9119052D0 (enExample)
IL (1) IL103005A (enExample)
IN (1) IN174169B (enExample)
RU (1) RU2123841C1 (enExample)
WO (1) WO1993004676A1 (enExample)
ZA (1) ZA926709B (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2164796C1 (ru) * 2000-05-25 2001-04-10 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Противогистаминное средство и способ его получения
RU2216318C2 (ru) * 1998-03-31 2003-11-20 Виатрис Гмбх Унд Ко. Кг. Твердая быстроразрушающаяся шипучая композиция цетиризина для перорального введения
RU2221553C2 (ru) * 1999-01-18 2004-01-20 Грюненталь Гмбх Способ изготовления округлых гранул
RU2254854C2 (ru) * 2003-09-08 2005-06-27 Открытое акционерное общество "Акционерное курганское общество медицинских препаратов и изделий "Синтез" Анальгезирующий, жаропонижающий, противовоспалительный препарат и способ его получения
RU2300368C2 (ru) * 2000-01-28 2007-06-10 Басф Акциенгезельшафт Содержащая ибупрофен композиция
RU2354374C2 (ru) * 2003-05-30 2009-05-10 РЕКИТТ БЕНКАЙЗЕР ХЭЛТКЭА (Ю Кей) ЛИМИТЕД Применение соединения для лечения нарушений сна

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101039B (fi) * 1992-10-09 1998-04-15 Eeva Kristoffersson Menetelmä lääkepellettien valmistamiseksi
HUP0104606A3 (en) * 1998-12-18 2003-01-28 Basf Ag A pharmaceutical mixture comprising a profen
US6726929B1 (en) 1998-12-18 2004-04-27 Basf Aktiengesellschaft Pharmaceutical mixture comprising a profen
US6251945B1 (en) * 1999-01-14 2001-06-26 Knoll Aktiengesellschaft Pharmaceutical mixture comprising a combination of a profen and other active compounds
US6962715B2 (en) * 2001-10-24 2005-11-08 Hewlett-Packard Development Company, L.P. Method and dosage form for dispensing a bioactive substance
US20040173147A1 (en) * 2001-06-07 2004-09-09 Figueroa Iddys D. Application of a bioactive agent to a delivery substrate
US20040173146A1 (en) * 2001-06-07 2004-09-09 Figueroa Iddys D. Application of a bioactive agent to a delivery substrate
DE10153934A1 (de) * 2001-11-06 2003-05-22 Basf Ag Verfahren zur Kristallisation von Profenen
US20050203482A1 (en) * 2004-03-15 2005-09-15 Chinea Vanessa I. Pharmaceutical dispensing apparatus and method
US20050202051A1 (en) * 2004-03-15 2005-09-15 Chinea Vanessa I. Pharmaceutical vehicle
JP2008266270A (ja) * 2007-04-25 2008-11-06 Kowa Co イブプロフェン、トラネキサム酸及び糖アルコールを含有する固形製剤
MX383484B (es) 2014-11-17 2025-03-11 Epizyme Inc Método para tratar el cáncer.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0298666A3 (en) * 1987-07-08 1989-05-17 American Home Products Corporation Spray dried ibuprofen compositions
WO1990008542A1 (en) * 1989-02-02 1990-08-09 Mallinckrodt, Inc. High ibuprofen content granulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240712A (en) * 1987-07-17 1993-08-31 The Boots Company Plc Therapeutic agents
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
US5266723A (en) * 1989-05-16 1993-11-30 Medice, Ltd., Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids
US5087454A (en) * 1990-07-30 1992-02-11 American Home Products Corporation Ibuprofen tablet
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations
US5332834A (en) * 1992-12-02 1994-07-26 Hoechst Celanese Corporation Racemization of an enantomerically enriched α-aryl carboxylic acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0298666A3 (en) * 1987-07-08 1989-05-17 American Home Products Corporation Spray dried ibuprofen compositions
WO1990008542A1 (en) * 1989-02-02 1990-08-09 Mallinckrodt, Inc. High ibuprofen content granulations

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2216318C2 (ru) * 1998-03-31 2003-11-20 Виатрис Гмбх Унд Ко. Кг. Твердая быстроразрушающаяся шипучая композиция цетиризина для перорального введения
RU2221553C2 (ru) * 1999-01-18 2004-01-20 Грюненталь Гмбх Способ изготовления округлых гранул
RU2300368C2 (ru) * 2000-01-28 2007-06-10 Басф Акциенгезельшафт Содержащая ибупрофен композиция
RU2164796C1 (ru) * 2000-05-25 2001-04-10 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Противогистаминное средство и способ его получения
RU2354374C2 (ru) * 2003-05-30 2009-05-10 РЕКИТТ БЕНКАЙЗЕР ХЭЛТКЭА (Ю Кей) ЛИМИТЕД Применение соединения для лечения нарушений сна
RU2254854C2 (ru) * 2003-09-08 2005-06-27 Открытое акционерное общество "Акционерное курганское общество медицинских препаратов и изделий "Синтез" Анальгезирующий, жаропонижающий, противовоспалительный препарат и способ его получения

Also Published As

Publication number Publication date
ZA926709B (en) 1993-04-28
AU2487092A (en) 1993-04-05
EP0602112B1 (en) 2007-02-07
CZ49994A3 (en) 1994-07-13
DE69233678T2 (de) 2008-01-24
IL103005A (en) 1996-01-19
WO1993004676A1 (en) 1993-03-18
CA2116956C (en) 2002-07-16
FI941046A0 (fi) 1994-03-04
AU655673B2 (en) 1995-01-05
JP3444597B2 (ja) 2003-09-08
GB9119052D0 (en) 1991-10-23
FI107878B (fi) 2001-10-31
KR100253046B1 (ko) 2000-05-01
ATE353213T1 (de) 2007-02-15
FI941046A7 (fi) 1994-03-04
US5512302A (en) 1996-04-30
EP0602112A1 (en) 1994-06-22
IN174169B (enExample) 1994-10-01
IL103005A0 (en) 1993-01-31
JPH06510532A (ja) 1994-11-24
CA2116956A1 (en) 1993-03-18
CZ282271B6 (cs) 1997-06-11
DE69233678D1 (de) 2007-03-22

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20040826