RU2114120C1 - Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция - Google Patents

Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция Download PDF

Info

Publication number
RU2114120C1
RU2114120C1 RU93058185A RU93058185A RU2114120C1 RU 2114120 C1 RU2114120 C1 RU 2114120C1 RU 93058185 A RU93058185 A RU 93058185A RU 93058185 A RU93058185 A RU 93058185A RU 2114120 C1 RU2114120 C1 RU 2114120C1
Authority
RU
Russia
Prior art keywords
igf
bsifr
protein
bsif
bone
Prior art date
Application number
RU93058185A
Other languages
English (en)
Russian (ru)
Other versions
RU93058185A (ru
Inventor
Мохан Суббураман
Дж.Бэйлинк Дэвид
Original Assignee
Берингер Маннхайм ГмбХ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Берингер Маннхайм ГмбХ filed Critical Берингер Маннхайм ГмбХ
Publication of RU93058185A publication Critical patent/RU93058185A/ru
Application granted granted Critical
Publication of RU2114120C1 publication Critical patent/RU2114120C1/ru

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU93058185A 1991-04-19 1992-04-15 Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция RU2114120C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68835391A 1991-04-19 1991-04-19
US688353 1991-04-19
US688,353 1991-04-19

Publications (2)

Publication Number Publication Date
RU93058185A RU93058185A (ru) 1996-11-10
RU2114120C1 true RU2114120C1 (ru) 1998-06-27

Family

ID=24764088

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93058185A RU2114120C1 (ru) 1991-04-19 1992-04-15 Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция

Country Status (11)

Country Link
EP (1) EP0580752A4 (fi)
JP (1) JP2527896B2 (fi)
KR (1) KR0129864B1 (fi)
AU (1) AU658187B2 (fi)
CA (1) CA2107475A1 (fi)
CZ (1) CZ283601B6 (fi)
FI (1) FI934588A (fi)
HU (1) HUT70297A (fi)
NO (1) NO933742L (fi)
RU (1) RU2114120C1 (fi)
WO (1) WO1992018154A1 (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8642037B2 (en) 2001-01-05 2014-02-04 Amgen Fremont Inc. Antibodies to insulin-like growth factor I receptor

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69233155T2 (de) 1991-01-08 2004-06-03 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Insulinartigen wachstumsfaktor bindendes protein
US5407913A (en) * 1992-12-03 1995-04-18 Celtrix Pharmaceuticals, Inc. Method and composition for systemic treatment of tissue injury
US5643867A (en) * 1992-08-26 1997-07-01 Celtrix Pharmaceuticals, Inc. Method for treating catabolic conditions
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
AU713275B2 (en) * 1994-07-20 1999-11-25 Celtrix Pharmaceuticals, Inc. IGF/IGFBP complex for promoting bone formation and for regulating bone remodeling
DK1486565T3 (da) 1995-10-11 2008-03-10 Novartis Vaccines & Diagnostic Kombination af PDGF, KGF, IGF og IGFBP til sårheling
WO2017117236A1 (en) * 2015-12-31 2017-07-06 Siemens Healthcare Diagnostics Inc. Non-recombinant human insulin-like growth factor binding protein concentrate
JP7077229B2 (ja) * 2015-12-31 2022-05-30 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 非組み換えヒトインスリン様成長因子結合タンパク質の濃縮物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7907958A (nl) * 1979-10-30 1981-06-01 Wijn Adriaan Jacques De Kar of onderstel voorzien van opklapbare wielen.
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
ES2063033T3 (es) * 1987-04-28 1995-01-01 Boehringer Mannheim Gmbh Empleo de igf-ii en el tratamiento de la enfermedades de los huesos.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Proc. Natl. Acad. Sci., USA, v. 86, p. 8338 - 8342, 1989. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8642037B2 (en) 2001-01-05 2014-02-04 Amgen Fremont Inc. Antibodies to insulin-like growth factor I receptor
US9234041B2 (en) 2001-01-05 2016-01-12 Pfizer Inc. Antibodies to insulin-like growth factor I receptor

Also Published As

Publication number Publication date
EP0580752A1 (en) 1994-02-02
NO933742L (no) 1993-10-18
CA2107475A1 (en) 1992-10-20
EP0580752A4 (en) 1994-08-24
AU658187B2 (en) 1995-04-06
CZ283601B6 (cs) 1998-05-13
JP2527896B2 (ja) 1996-08-28
HUT70297A (en) 1995-09-28
HU9302942D0 (en) 1994-01-28
KR0129864B1 (en) 1998-04-09
WO1992018154A1 (en) 1992-10-29
FI934588A0 (fi) 1993-10-18
AU1784492A (en) 1992-11-17
FI934588A (fi) 1993-10-18
CZ219093A3 (en) 1994-12-15
JPH06501270A (ja) 1994-02-10

Similar Documents

Publication Publication Date Title
Wolf et al. Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model.
AU670770B2 (en) Inhibiting transforming growth factor beta to prevent accumulation of extracellular matrix
EP0494264B1 (en) Inhibiting transforming growth factor to prevent accumulation of extracellular matrix
JP3053116B2 (ja) 医薬組成物
EP0559769B1 (en) Heparin binding mitogen with homology to epidermal growth factor (egf)
EP0369943B1 (en) Binding protein for insulin-like growth factors
JP2648951B2 (ja) 人体のソマトメジン担体蛋白質サブユニットとこれらの製法
JPH05506030A (ja) 哺乳動物に組織修復促進の傾向を与える方法
KR19990066981A (ko) 치료용 맥관형성억제 조성물 및 방법
US7795215B2 (en) MNTF peptides and compositions and methods of use
RU2114120C1 (ru) Белок, связывающий инсулин-подобный фактор роста, фармацевтическая композиция
Phillips et al. Nutrition and somatomedin. XI. Studies of somatomedin inhibitors in rats with streptozotocin-induced diabetes
WO1998004245A1 (en) Use of transglutaminase modulators to promote wound healing
Eisenstein et al. Growth inhibitory activities in avascular tissues are recognized by anti-transforming growth factor β antibodies
EP0384731A2 (en) Osteogenic growth polypeptides identified from regenerating bone marrow
WO1999049894A1 (en) Antagonists to growth arrest specific gene 6 to treat insulin-resistant disorders
US5693754A (en) Inhibitory binding protein for insulin-like growth factors
CA1295940C (en) Therapeutic treatment of abnormal cell growth with follicle regulatoryprotein
US20060153830A1 (en) Proteases from Carica having mitogenic activity and their methods of use
CA2191321A1 (en) Gene coding for modified bone morphogenic protein receptor
US20030223984A1 (en) Proteases from carica having mitogenic activity and their methods of use
AU2079900A (en) Inhibiting transforming growth factor beta to prevent accumulation of extracellular matrix
WO1992013888A1 (en) Epithelial cell wound healing compositions and method