RU2075481C1 - Производные борсодержащих пептидов и фармацевтическая композиция, обладающая ингибирующей активностью к трипсинподобным сериновым протеазам - Google Patents

Производные борсодержащих пептидов и фармацевтическая композиция, обладающая ингибирующей активностью к трипсинподобным сериновым протеазам Download PDF

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Publication number
RU2075481C1
RU2075481C1 SU915001319A SU5001319A RU2075481C1 RU 2075481 C1 RU2075481 C1 RU 2075481C1 SU 915001319 A SU915001319 A SU 915001319A SU 5001319 A SU5001319 A SU 5001319A RU 2075481 C1 RU2075481 C1 RU 2075481C1
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Russia
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pro
mmol
formula
group
tmsal
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SU915001319A
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Russian (ru)
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Меттерних Райнер
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Сандос АГ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SU915001319A 1990-08-13 1991-08-12 Производные борсодержащих пептидов и фармацевтическая композиция, обладающая ингибирующей активностью к трипсинподобным сериновым протеазам RU2075481C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9017694 1990-08-13
GB909017694A GB9017694D0 (en) 1990-08-13 1990-08-13 Improvements in or relating to organic chemistry

Publications (1)

Publication Number Publication Date
RU2075481C1 true RU2075481C1 (ru) 1997-03-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
SU915001319A RU2075481C1 (ru) 1990-08-13 1991-08-12 Производные борсодержащих пептидов и фармацевтическая композиция, обладающая ингибирующей активностью к трипсинподобным сериновым протеазам

Country Status (18)

Country Link
EP (1) EP0471651A3 (enExample)
JP (1) JP2539965B2 (enExample)
KR (1) KR920004416A (enExample)
AU (1) AU643312B2 (enExample)
CA (1) CA2048953A1 (enExample)
CS (1) CS248491A3 (enExample)
FI (1) FI913788A7 (enExample)
GB (1) GB9017694D0 (enExample)
HU (1) HUT59161A (enExample)
IE (1) IE912841A1 (enExample)
IL (1) IL99163A (enExample)
MX (1) MX9100628A (enExample)
MY (1) MY106529A (enExample)
NZ (1) NZ239359A (enExample)
PT (1) PT98638B (enExample)
RU (1) RU2075481C1 (enExample)
TW (1) TW275634B (enExample)
ZA (1) ZA916393B (enExample)

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US5462964A (en) * 1993-10-20 1995-10-31 The Du Pont Merck Pharmaceutical Company Dipeptide boronic acid inhibitors of trypsin-like enzymes
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US5693617A (en) * 1994-03-15 1997-12-02 Proscript, Inc. Inhibitors of the 26s proteolytic complex and the 20s proteasome contained therein
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US5510369A (en) * 1994-07-22 1996-04-23 Merck & Co., Inc. Pyrrolidine thrombin inhibitors
US6083903A (en) 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
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US5629324A (en) * 1995-04-10 1997-05-13 Merck & Co., Inc. Thrombin inhibitors
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US5965532A (en) 1996-06-28 1999-10-12 Trustees Of Tufts College Multivalent compounds for crosslinking receptors and uses thereof
US6004955A (en) * 1996-08-15 1999-12-21 Dupont Pharmaceuticals Company Cyclic carbamates and isoxazolidines as IIb/IIIa antagonists
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
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US6100234A (en) 1997-05-07 2000-08-08 Tufts University Treatment of HIV
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Also Published As

Publication number Publication date
PT98638B (pt) 1999-01-29
GB9017694D0 (en) 1990-09-26
PT98638A (pt) 1992-06-30
HU912541D0 (en) 1992-01-28
IL99163A (en) 1996-01-19
FI913788A0 (fi) 1991-08-09
AU643312B2 (en) 1993-11-11
IE912841A1 (en) 1992-02-26
FI913788L (fi) 1992-02-14
JPH04330094A (ja) 1992-11-18
AU8179291A (en) 1992-02-20
TW275634B (enExample) 1996-05-11
MY106529A (en) 1995-06-30
EP0471651A2 (en) 1992-02-19
HUT59161A (en) 1992-04-28
FI913788A7 (fi) 1992-02-14
IL99163A0 (en) 1992-07-15
JP2539965B2 (ja) 1996-10-02
EP0471651A3 (en) 1993-02-10
CA2048953A1 (en) 1992-02-14
CS248491A3 (en) 1992-02-19
ZA916393B (en) 1993-04-28
KR920004416A (ko) 1992-03-27
NZ239359A (en) 1993-09-27
MX9100628A (es) 1994-02-28

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