RU2019141996A - Клеточная система и способ хранения клеток - Google Patents
Клеточная система и способ хранения клеток Download PDFInfo
- Publication number
- RU2019141996A RU2019141996A RU2019141996A RU2019141996A RU2019141996A RU 2019141996 A RU2019141996 A RU 2019141996A RU 2019141996 A RU2019141996 A RU 2019141996A RU 2019141996 A RU2019141996 A RU 2019141996A RU 2019141996 A RU2019141996 A RU 2019141996A
- Authority
- RU
- Russia
- Prior art keywords
- cells
- cell system
- paragraphs
- nanofibrillar cellulose
- cell
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 6
- 210000004027 cell Anatomy 0.000 claims 26
- 239000001913 cellulose Substances 0.000 claims 12
- 229920002678 cellulose Polymers 0.000 claims 12
- 239000000017 hydrogel Substances 0.000 claims 6
- 239000002609 medium Substances 0.000 claims 5
- 210000003527 eukaryotic cell Anatomy 0.000 claims 4
- 238000002560 therapeutic procedure Methods 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- 230000001413 cellular effect Effects 0.000 claims 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 2
- 238000003776 cleavage reaction Methods 0.000 claims 2
- 230000002255 enzymatic effect Effects 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 2
- 230000007017 scission Effects 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 claims 1
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 102000005575 Cellulases Human genes 0.000 claims 1
- 108010084185 Cellulases Proteins 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000006172 buffering agent Substances 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000002357 osmotic agent Substances 0.000 claims 1
- 230000003204 osmotic effect Effects 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 210000001912 transporting cell Anatomy 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/128—Chemically defined matrices for immobilising, holding or storing living parts, e.g. alginate gels; Chemically altering living parts, e.g. by cross-linking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/78—Cellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Dispersion Chemistry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18397536.6A EP3669651B1 (en) | 2018-12-21 | 2018-12-21 | Cell system and method for storing cells |
| EP18397536.6 | 2018-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2019141996A true RU2019141996A (ru) | 2021-06-18 |
Family
ID=65010529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019141996A RU2019141996A (ru) | 2018-12-21 | 2019-12-18 | Клеточная система и способ хранения клеток |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11332714B2 (https=) |
| EP (1) | EP3669651B1 (https=) |
| JP (1) | JP7285767B2 (https=) |
| CN (1) | CN111345281B (https=) |
| CA (1) | CA3062871C (https=) |
| RU (1) | RU2019141996A (https=) |
| SG (1) | SG10201912442SA (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114026223A (zh) * | 2019-06-24 | 2022-02-08 | 芬欧汇川集团 | 包含位于纳米原纤纤维素水凝胶中的真核细胞的可移植细胞组合物、其制备方法和纳米原纤纤维素的用途 |
| CN113133445B (zh) * | 2021-04-28 | 2022-09-06 | 河南省人民医院 | 一种间充质干细胞的保存方法、运输方法及其处理方法 |
| FI131311B1 (en) * | 2021-09-13 | 2025-02-07 | Upm Kymmene Corp | Method for preparing microbeads, microbeads, a cell culture and cell storage system consisting of microbeads, and use of chemically anionically modified nanofibrillated cellulose |
| EP4227401A1 (en) * | 2022-02-11 | 2023-08-16 | UPM-Kymmene Corporation | An ex vivo tumour immune microenvironment model, a method for preserving a tumour-specific immune cell profile in an ex vivo tumour immune microenvironment model and use of nanofibrillar cellulose |
| WO2023190797A1 (ja) * | 2022-03-30 | 2023-10-05 | 味の素株式会社 | 筋質改善用組成物 |
| KR20250127298A (ko) * | 2022-12-21 | 2025-08-26 | 셀레베이트 에이비 | 세포 배양용 나노섬유 스캐폴드 |
| FI20236033A1 (en) * | 2023-09-18 | 2025-03-19 | 2 Fresh Finland Oy | Method for freezing a mixture consisting of biological material |
| FI20236062A1 (en) * | 2023-09-26 | 2025-03-27 | Upm Kymmene Corp | CONTROLLED RELEASE NANOCELLULOSE COMPOSITIONS AND METHOD FOR MANUFACTURING THEREOF |
| WO2025259876A1 (en) * | 2024-06-12 | 2025-12-18 | Likarda, Inc. | Temporary protective polymer-based matrices for cold chain transportation and recovery of biological materials |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2192103C (en) * | 1994-06-06 | 2002-02-05 | Arnold I. Caplan | Biomatrix for tissue regeneration |
| US8926933B2 (en) * | 2004-11-09 | 2015-01-06 | The Board Of Regents Of The University Of Texas System | Fabrication of twisted and non-twisted nanofiber yarns |
| ES2343721B1 (es) * | 2008-12-19 | 2011-06-06 | Histocell, S.L. | Sistema de transporte de celulas. |
| FI126398B (en) * | 2014-12-18 | 2016-11-15 | Upm Kymmene Corp | Method for chemical testing |
| CA2984598C (en) * | 2015-05-04 | 2022-06-14 | Upm-Kymmene Corporation | Nanofibrillar cellulose product |
| FI127765B (en) | 2015-05-13 | 2019-02-15 | Upm Kymmene Corp | WATER PURIFICATION |
| EP3335695B1 (en) | 2016-12-15 | 2020-02-05 | UPM-Kymmene Corporation | A method for freeze-drying hydrogel comprising nanofibrillar cellulose, a freeze-dried medical hydrogel comprising nanofibrillar cellulose, and a hydrogel comprising nanofibrillar cellulose |
| EP3335740B1 (en) * | 2016-12-15 | 2024-07-24 | UPM-Kymmene Corporation | Medical hydrogel |
| EP3418377B1 (en) | 2017-06-22 | 2024-04-17 | UPM-Kymmene Corporation | Supportive nanofibrillar cellulose scaffold for expanding cells |
| EP3581591A1 (en) | 2018-06-13 | 2019-12-18 | UPM-Kymmene Corporation | A nanofibrillar cellulose product and a method for manufacturing thereof |
-
2018
- 2018-12-21 EP EP18397536.6A patent/EP3669651B1/en active Active
-
2019
- 2019-11-27 CA CA3062871A patent/CA3062871C/en active Active
- 2019-12-13 JP JP2019225414A patent/JP7285767B2/ja active Active
- 2019-12-17 SG SG10201912442SA patent/SG10201912442SA/en unknown
- 2019-12-18 RU RU2019141996A patent/RU2019141996A/ru unknown
- 2019-12-18 US US16/718,284 patent/US11332714B2/en active Active
- 2019-12-20 CN CN201911325498.8A patent/CN111345281B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7285767B2 (ja) | 2023-06-02 |
| CN111345281B (zh) | 2022-10-28 |
| US11332714B2 (en) | 2022-05-17 |
| JP2020103281A (ja) | 2020-07-09 |
| CA3062871A1 (en) | 2020-06-21 |
| SG10201912442SA (en) | 2020-07-29 |
| US20200199536A1 (en) | 2020-06-25 |
| EP3669651C0 (en) | 2023-07-05 |
| CA3062871C (en) | 2024-02-20 |
| EP3669651B1 (en) | 2023-07-05 |
| CN111345281A (zh) | 2020-06-30 |
| EP3669651A1 (en) | 2020-06-24 |
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