JP2019514442A5 - - Google Patents
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- Publication number
- JP2019514442A5 JP2019514442A5 JP2019512183A JP2019512183A JP2019514442A5 JP 2019514442 A5 JP2019514442 A5 JP 2019514442A5 JP 2019512183 A JP2019512183 A JP 2019512183A JP 2019512183 A JP2019512183 A JP 2019512183A JP 2019514442 A5 JP2019514442 A5 JP 2019514442A5
- Authority
- JP
- Japan
- Prior art keywords
- medium
- cells
- macromolecule
- polymer
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002609 medium Substances 0.000 claims 23
- 210000004027 cell Anatomy 0.000 claims 17
- 229920002521 macromolecule Polymers 0.000 claims 11
- 239000007788 liquid Substances 0.000 claims 8
- 238000007710 freezing Methods 0.000 claims 7
- 230000008014 freezing Effects 0.000 claims 7
- 229920000642 polymer Polymers 0.000 claims 7
- 239000006285 cell suspension Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 102000034238 globular proteins Human genes 0.000 claims 4
- 108091005896 globular proteins Proteins 0.000 claims 4
- 238000001816 cooling Methods 0.000 claims 3
- 239000002577 cryoprotective agent Substances 0.000 claims 3
- 210000004962 mammalian cell Anatomy 0.000 claims 3
- 239000000725 suspension Substances 0.000 claims 3
- 238000010257 thawing Methods 0.000 claims 3
- 230000003833 cell viability Effects 0.000 claims 2
- 238000004108 freeze drying Methods 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 231100000252 nontoxic Toxicity 0.000 claims 2
- 230000003000 nontoxic effect Effects 0.000 claims 2
- 229920000858 Cyclodextrin Polymers 0.000 claims 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 102000003839 Human Proteins Human genes 0.000 claims 1
- 108090000144 Human Proteins Proteins 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- 235000021120 animal protein Nutrition 0.000 claims 1
- 239000007798 antifreeze agent Substances 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 238000005056 compaction Methods 0.000 claims 1
- 238000007334 copolymerization reaction Methods 0.000 claims 1
- 230000000959 cryoprotective effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 150000002482 oligosaccharides Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 238000001953 recrystallisation Methods 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000001082 somatic cell Anatomy 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 238000000859 sublimation Methods 0.000 claims 1
- 230000008022 sublimation Effects 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 230000035899 viability Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662336142P | 2016-05-13 | 2016-05-13 | |
| US62/336,142 | 2016-05-13 | ||
| PCT/US2017/032606 WO2017197379A1 (en) | 2016-05-13 | 2017-05-15 | Cryopreservation medium and method to prevent recrystallization |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019514442A JP2019514442A (ja) | 2019-06-06 |
| JP2019514442A5 true JP2019514442A5 (https=) | 2020-06-25 |
Family
ID=60267661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019512183A Pending JP2019514442A (ja) | 2016-05-13 | 2017-05-15 | 凍結防止培地及び再結晶防止方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20190313632A1 (https=) |
| EP (1) | EP3454653A4 (https=) |
| JP (1) | JP2019514442A (https=) |
| CN (1) | CN109414008A (https=) |
| WO (1) | WO2017197379A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201716729D0 (en) * | 2017-10-12 | 2017-11-29 | Asymptote Ltd | Cryopreservation method and apparatus |
| JP7391528B2 (ja) * | 2019-02-15 | 2023-12-05 | イビデン株式会社 | 凍結保存用高分子水溶液 |
| WO2020198693A1 (en) * | 2019-03-27 | 2020-10-01 | EMULATE, Inc. | Microfluidic devices for tattoo pigment safety |
| WO2021159073A1 (en) | 2020-02-06 | 2021-08-12 | The George Washington University | Methods and compositions for cryopreservation of cell therapies |
| US12426594B2 (en) | 2020-09-24 | 2025-09-30 | Everest Medical Innovation GmbH | Cryoprotective compositions and methods for protection of a surgical site during cryosurgery |
| US12453805B2 (en) | 2020-09-24 | 2025-10-28 | Everest Medical Innovation GmbH | Cryoprotective compositions, surgical kits, and methods for protection of a surgical site during cryosurgery |
| CN112293411B (zh) * | 2020-11-27 | 2021-09-28 | 大连海洋大学 | 中间球海胆精子的低温保存液及保存方法 |
| CN117177663A (zh) * | 2021-04-05 | 2023-12-05 | 库瑞欧库瑞特有限公司 | 消除了对细胞渗透性防冻剂的需要的高效生物相容性冷冻保存培养基 |
| CN113491267A (zh) * | 2021-07-22 | 2021-10-12 | 南昌市生殖医院 | 一种微量精子冷冻保存载体及相应的冷冻和解冻方法 |
| WO2025019400A1 (en) * | 2023-07-14 | 2025-01-23 | Cryocrate Llc | Efficient cryopreservation medium that preserves tissue ultra-structures and eliminates tissue cells |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4362756A (en) * | 1981-12-28 | 1982-12-07 | Borden, Inc. | Brown sugar sweetened condensed milk and process for preparation thereof |
| US5171661A (en) * | 1988-05-18 | 1992-12-15 | Cryopharm Corporation | Medium for lyophilization of erythrocytes |
| US5629145A (en) * | 1995-03-24 | 1997-05-13 | Organ, Inc. | Cryopreservation of cell suspensions |
| US20020051963A1 (en) * | 1999-03-05 | 2002-05-02 | Victor Bronshtein | Shelf preservation of cells, tissues, organs and organisms by vitrification |
| US20060051731A1 (en) * | 2004-08-12 | 2006-03-09 | David Ho | Processes for preparing lyophilized platelets |
| JP5553332B2 (ja) * | 2009-08-12 | 2014-07-16 | 独立行政法人理化学研究所 | 生物材料用ガラス化液、ガラス化キット、及びその利用 |
| WO2013096659A1 (en) * | 2011-12-20 | 2013-06-27 | Cook General Biotechnology Llc | Methods and compositions for storage of animal cells |
| CN103184189A (zh) * | 2011-12-29 | 2013-07-03 | 北京富通华生物科技有限公司 | 一种杂交和牛的培育方法 |
| CN102657152B (zh) * | 2012-05-04 | 2014-06-25 | 南京林业大学 | 一种胚性材料的超低温冷冻保存方法 |
| CN104988115A (zh) * | 2015-07-14 | 2015-10-21 | 中国科学院过程工程研究所 | 喹啉或异喹啉类小分子化合物在人多能干细胞培养及冷冻保存中的应用 |
-
2017
- 2017-05-15 US US16/300,970 patent/US20190313632A1/en not_active Abandoned
- 2017-05-15 WO PCT/US2017/032606 patent/WO2017197379A1/en not_active Ceased
- 2017-05-15 EP EP17797016.7A patent/EP3454653A4/en not_active Withdrawn
- 2017-05-15 CN CN201780028522.4A patent/CN109414008A/zh active Pending
- 2017-05-15 JP JP2019512183A patent/JP2019514442A/ja active Pending
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