RU2017129236A3 - - Google Patents

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Publication number
RU2017129236A3
RU2017129236A3 RU2017129236A RU2017129236A RU2017129236A3 RU 2017129236 A3 RU2017129236 A3 RU 2017129236A3 RU 2017129236 A RU2017129236 A RU 2017129236A RU 2017129236 A RU2017129236 A RU 2017129236A RU 2017129236 A3 RU2017129236 A3 RU 2017129236A3
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RU
Russia
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RU2017129236A
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Russian (ru)
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RU2017129236A (ru
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Publication of RU2017129236A3 publication Critical patent/RU2017129236A3/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/35Valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2017129236A 2015-01-26 2015-05-29 Мультивалентные молекулы, содержащие dr5-связывающие домены RU2017129236A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562107871P 2015-01-26 2015-01-26
US62/107,871 2015-01-26
US201562149139P 2015-04-17 2015-04-17
US62/149,139 2015-04-17
PCT/US2015/033099 WO2016122702A1 (en) 2015-01-26 2015-05-29 Multivalent molecules comprising dr5-binding domains

Publications (2)

Publication Number Publication Date
RU2017129236A RU2017129236A (ru) 2019-03-07
RU2017129236A3 true RU2017129236A3 (enExample) 2019-03-07

Family

ID=56544108

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017129236A RU2017129236A (ru) 2015-01-26 2015-05-29 Мультивалентные молекулы, содержащие dr5-связывающие домены

Country Status (13)

Country Link
US (1) US10501552B2 (enExample)
EP (1) EP3250601A4 (enExample)
JP (1) JP6602875B2 (enExample)
KR (1) KR20170105622A (enExample)
CN (1) CN107250161A (enExample)
AU (1) AU2015380455A1 (enExample)
CA (1) CA2974807A1 (enExample)
HK (1) HK1247215A1 (enExample)
IL (1) IL253668A0 (enExample)
RU (1) RU2017129236A (enExample)
SG (1) SG11201706024YA (enExample)
TW (1) TWI688572B (enExample)
WO (1) WO2016122702A1 (enExample)

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KR102194026B1 (ko) * 2017-12-15 2020-12-22 경북대학교 산학협력단 Trail 수용체에 결합하는 펩타이드 및 이의 용도
CN112243444A (zh) * 2018-06-08 2021-01-19 豪夫迈·罗氏有限公司 具有减少的翻译后修饰的肽接头
WO2020027330A1 (ja) * 2018-08-03 2020-02-06 中外製薬株式会社 互いに連結された2つの抗原結合ドメインを含む抗原結合分子
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
US20230312737A1 (en) * 2020-03-04 2023-10-05 Regents Of The University Of Minnesota Anti-dr5 polypeptides and methods of use thereof
EP4337699A4 (en) * 2021-05-12 2025-07-23 Biolegend Inc ANTI-CCR8 ANTIBODIES, ANTIGEN-BINDING FRAGMENTS THEREOF, AND AGENTS AND COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
WO2024149381A1 (en) * 2023-01-13 2024-07-18 Shanghai Kaijin Biotechnology, Ltd Multi-specific polypeptide complexes
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JP2018507188A (ja) 2018-03-15
CA2974807A1 (en) 2016-08-04
RU2017129236A (ru) 2019-03-07
IL253668A0 (en) 2017-09-28
HK1247215A1 (zh) 2018-09-21
KR20170105622A (ko) 2017-09-19
US20180016344A1 (en) 2018-01-18
AU2015380455A1 (en) 2017-08-03
WO2016122702A1 (en) 2016-08-04
TWI688572B (zh) 2020-03-21
SG11201706024YA (en) 2017-08-30
CN107250161A (zh) 2017-10-13
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