RU2016141088A - 5-замещённые индазол-3-карбоксамиды и их получение и применение - Google Patents

5-замещённые индазол-3-карбоксамиды и их получение и применение Download PDF

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RU2016141088A
RU2016141088A RU2016141088A RU2016141088A RU2016141088A RU 2016141088 A RU2016141088 A RU 2016141088A RU 2016141088 A RU2016141088 A RU 2016141088A RU 2016141088 A RU2016141088 A RU 2016141088A RU 2016141088 A RU2016141088 A RU 2016141088A
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pyridin
carboxamide
indazole
ylmethyl
piperidin
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RU2016141088A
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Russian (ru)
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RU2016141088A3 (cg-RX-API-DMAC7.html
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Джон ХУД
Сунил Кумар КС
Дэвид Марк УОЛЛЭЙС
Гопи Кумар МИТТАПАЛЛИ
Брайн Джозеф ХОФИЛЕНА
Чи Чин МАК
Венкатаях Боллу
Брайан Истман
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СЭМЬЮМЕД, ЭлЭлСи
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Publication of RU2016141088A publication Critical patent/RU2016141088A/ru
Publication of RU2016141088A3 publication Critical patent/RU2016141088A3/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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RU2016141088A 2014-03-20 2015-03-20 5-замещённые индазол-3-карбоксамиды и их получение и применение RU2016141088A (ru)

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Application Number Priority Date Filing Date Title
US201461968350P 2014-03-20 2014-03-20
US61/968,350 2014-03-20
PCT/US2015/021847 WO2015143380A1 (en) 2014-03-20 2015-03-20 5-substituted indazole-3-carboxamides and preparation and use thereof

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RU2016141088A true RU2016141088A (ru) 2018-04-25
RU2016141088A3 RU2016141088A3 (cg-RX-API-DMAC7.html) 2018-11-20

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US (2) US9745271B2 (cg-RX-API-DMAC7.html)
EP (1) EP3119393A4 (cg-RX-API-DMAC7.html)
JP (1) JP6586104B2 (cg-RX-API-DMAC7.html)
KR (1) KR20160135283A (cg-RX-API-DMAC7.html)
CN (1) CN106535890A (cg-RX-API-DMAC7.html)
BR (1) BR112016021626A2 (cg-RX-API-DMAC7.html)
CA (1) CA2942687A1 (cg-RX-API-DMAC7.html)
CL (1) CL2016002364A1 (cg-RX-API-DMAC7.html)
IL (1) IL247713A0 (cg-RX-API-DMAC7.html)
MA (1) MA39763A (cg-RX-API-DMAC7.html)
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PE (1) PE20170127A1 (cg-RX-API-DMAC7.html)
PH (1) PH12016501835A1 (cg-RX-API-DMAC7.html)
RU (1) RU2016141088A (cg-RX-API-DMAC7.html)
SG (2) SG10201914111XA (cg-RX-API-DMAC7.html)
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CN105120862A (zh) 2013-01-08 2015-12-02 萨穆梅德有限公司 Wnt信号途径的3-(苯并咪唑-2-基)-吲唑抑制剂及其治疗应用
US9745271B2 (en) 2014-03-20 2017-08-29 Samumed, Llc 5-substituted indazole-3-carboxamides and preparation and use thereof
WO2016040185A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040190A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040180A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
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US10463651B2 (en) 2015-08-03 2019-11-05 Samumed, Llc 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-indazoles and therapeutic uses thereof
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WO2017023972A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10226453B2 (en) 2015-08-03 2019-03-12 Samumed, Llc 3-(1H-indol-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
US10350199B2 (en) 2015-08-03 2019-07-16 Samumed, Llc 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
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