RU2015131480A - Композиции и способы для биологического получения изопрена - Google Patents
Композиции и способы для биологического получения изопрена Download PDFInfo
- Publication number
- RU2015131480A RU2015131480A RU2015131480A RU2015131480A RU2015131480A RU 2015131480 A RU2015131480 A RU 2015131480A RU 2015131480 A RU2015131480 A RU 2015131480A RU 2015131480 A RU2015131480 A RU 2015131480A RU 2015131480 A RU2015131480 A RU 2015131480A
- Authority
- RU
- Russia
- Prior art keywords
- isoprene
- nucleic acid
- methanotrophic
- methanotrophic bacterium
- exogenous nucleic
- Prior art date
Links
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 title claims 64
- 238000000034 method Methods 0.000 title claims 36
- 239000000203 mixture Substances 0.000 title claims 7
- 241000994220 methanotrophic bacterium Species 0.000 claims 42
- 150000007523 nucleic acids Chemical class 0.000 claims 37
- 108020004707 nucleic acids Proteins 0.000 claims 36
- 102000039446 nucleic acids Human genes 0.000 claims 36
- 230000037361 pathway Effects 0.000 claims 33
- 102000004190 Enzymes Human genes 0.000 claims 31
- 108090000790 Enzymes Proteins 0.000 claims 31
- 241000894006 Bacteria Species 0.000 claims 12
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims 12
- 230000001450 methanotrophic effect Effects 0.000 claims 12
- 108010007508 Farnesyltranstransferase Proteins 0.000 claims 7
- 102100039291 Geranylgeranyl pyrophosphate synthase Human genes 0.000 claims 7
- 229910052799 carbon Inorganic materials 0.000 claims 7
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 6
- KJTLQQUUPVSXIM-ZCFIWIBFSA-M (R)-mevalonate Chemical compound OCC[C@](O)(C)CC([O-])=O KJTLQQUUPVSXIM-ZCFIWIBFSA-M 0.000 claims 5
- KJTLQQUUPVSXIM-UHFFFAOYSA-N DL-mevalonic acid Natural products OCCC(O)(C)CC(O)=O KJTLQQUUPVSXIM-UHFFFAOYSA-N 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 4
- 241000589966 Methylocystis Species 0.000 claims 4
- 241000589348 Methylomonas methanica Species 0.000 claims 4
- 241000168036 Populus alba Species 0.000 claims 4
- 229930195733 hydrocarbon Natural products 0.000 claims 4
- 150000002430 hydrocarbons Chemical class 0.000 claims 4
- 108010075483 isoprene synthase Proteins 0.000 claims 4
- 239000003345 natural gas Substances 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108020004705 Codon Proteins 0.000 claims 3
- 150000001413 amino acids Chemical group 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 230000019612 pigmentation Effects 0.000 claims 3
- 101100453077 Botryococcus braunii HDR gene Proteins 0.000 claims 2
- 239000004215 Carbon black (E152) Substances 0.000 claims 2
- 102100031515 D-ribitol-5-phosphate cytidylyltransferase Human genes 0.000 claims 2
- 101710088194 Dehydrogenase Proteins 0.000 claims 2
- 101000994204 Homo sapiens D-ribitol-5-phosphate cytidylyltransferase Proteins 0.000 claims 2
- 241000267306 Methylacidiphilum fumariolicum Species 0.000 claims 2
- 241000672512 Methylacidiphilum infernorum Species 0.000 claims 2
- 241001512042 Methylibium petroleiphilum Species 0.000 claims 2
- 241000922210 Methyloacida Species 0.000 claims 2
- 241000589350 Methylobacter Species 0.000 claims 2
- 241000589207 Methylobacter capsulatus Species 0.000 claims 2
- 241000589339 Methylobacterium organophilum Species 0.000 claims 2
- 241001085182 Methylocapsa Species 0.000 claims 2
- 241000566791 Methylocapsa aurea Species 0.000 claims 2
- 241000514364 Methylocella Species 0.000 claims 2
- 241001609650 Methylocella palustris Species 0.000 claims 2
- 241001533549 Methylocella silvestris Species 0.000 claims 2
- 241000314903 Methylocella tundrae Species 0.000 claims 2
- 241000589345 Methylococcus Species 0.000 claims 2
- 241000589346 Methylococcus capsulatus Species 0.000 claims 2
- 241000213422 Methylocystis bryophila Species 0.000 claims 2
- 241001533203 Methylomicrobium Species 0.000 claims 2
- 241001533199 Methylomicrobium album Species 0.000 claims 2
- 241000409693 Methylomicrobium alcaliphilum Species 0.000 claims 2
- 241000589344 Methylomonas Species 0.000 claims 2
- 241000589354 Methylosinus Species 0.000 claims 2
- 241000589349 Methylosinus sporium Species 0.000 claims 2
- 241000322541 Methylosinus trichosporium OB3b Species 0.000 claims 2
- 241000220435 Papilionoideae Species 0.000 claims 2
- 241001483078 Phyto Species 0.000 claims 2
- 101100397457 Plasmodium falciparum (isolate 3D7) LytB gene Proteins 0.000 claims 2
- 241000219000 Populus Species 0.000 claims 2
- 241000218982 Populus nigra Species 0.000 claims 2
- 241000183024 Populus tremula Species 0.000 claims 2
- 240000004923 Populus tremuloides Species 0.000 claims 2
- 235000011263 Populus tremuloides Nutrition 0.000 claims 2
- 241000218976 Populus trichocarpa Species 0.000 claims 2
- 235000010575 Pueraria lobata Nutrition 0.000 claims 2
- 241000913776 Pueraria montana Species 0.000 claims 2
- 241000219781 Pueraria montana var. lobata Species 0.000 claims 2
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 claims 2
- 241001278109 Salix discolor Species 0.000 claims 2
- 241001014730 Salix glabra Species 0.000 claims 2
- 241001278077 Salix pentandra Species 0.000 claims 2
- 241001299688 Salix serpyllifolia Species 0.000 claims 2
- 108010048916 alcohol dehydrogenase (acceptor) Proteins 0.000 claims 2
- 238000000855 fermentation Methods 0.000 claims 2
- 230000004151 fermentation Effects 0.000 claims 2
- 108010025743 hexose phosphate synthetase Proteins 0.000 claims 2
- 101150018742 ispF gene Proteins 0.000 claims 2
- 239000007011 methylocapsa aurea Substances 0.000 claims 2
- 239000003471 mutagenic agent Substances 0.000 claims 2
- 231100000707 mutagenic chemical Toxicity 0.000 claims 2
- 230000003505 mutagenic effect Effects 0.000 claims 2
- 210000002706 plastid Anatomy 0.000 claims 2
- 239000002243 precursor Substances 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- CABVTRNMFUVUDM-VRHQGPGLSA-N (3S)-3-hydroxy-3-methylglutaryl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C[C@@](O)(CC(O)=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 CABVTRNMFUVUDM-VRHQGPGLSA-N 0.000 claims 1
- 108030003618 3,4-dihydroxy-2-butanone-4-phosphate synthases Proteins 0.000 claims 1
- 102000005345 Acetyl-CoA C-acetyltransferase Human genes 0.000 claims 1
- 108010006229 Acetyl-CoA C-acetyltransferase Proteins 0.000 claims 1
- 102000057412 Diphosphomevalonate decarboxylases Human genes 0.000 claims 1
- 108090000895 Hydroxymethylglutaryl CoA Reductases Proteins 0.000 claims 1
- 102000004286 Hydroxymethylglutaryl CoA Reductases Human genes 0.000 claims 1
- 241000589964 Methylocystis parvus Species 0.000 claims 1
- 241000589342 Methylomonas sp. Species 0.000 claims 1
- 108700040132 Mevalonate kinases Proteins 0.000 claims 1
- 101000958834 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) Diphosphomevalonate decarboxylase mvd1 Proteins 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 101000958925 Panax ginseng Diphosphomevalonate decarboxylase 1 Proteins 0.000 claims 1
- 108091000041 Phosphoenolpyruvate Carboxylase Proteins 0.000 claims 1
- 102100024279 Phosphomevalonate kinase Human genes 0.000 claims 1
- 241000219492 Quercus Species 0.000 claims 1
- 240000009089 Quercus robur Species 0.000 claims 1
- 235000011471 Quercus robur Nutrition 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 108090000340 Transaminases Proteins 0.000 claims 1
- 102000003929 Transaminases Human genes 0.000 claims 1
- 150000001335 aliphatic alkanes Chemical class 0.000 claims 1
- 230000006696 biosynthetic metabolic pathway Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000007789 gas Substances 0.000 claims 1
- 238000005984 hydrogenation reaction Methods 0.000 claims 1
- -1 isopentenyl Chemical group 0.000 claims 1
- 102000002678 mevalonate kinase Human genes 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 108091000116 phosphomevalonate kinase Proteins 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 238000002708 random mutagenesis Methods 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 238000002741 site-directed mutagenesis Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 150000003505 terpenes Chemical class 0.000 claims 1
- 230000009466 transformation Effects 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C11/00—Aliphatic unsaturated hydrocarbons
- C07C11/02—Alkenes
- C07C11/10—Alkenes with five carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0093—Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01267—1-Deoxy-D-xylulose-5-phosphate reductoisomerase (1.1.1.267)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
- C12Y117/01—Oxidoreductases acting on CH or CH2 groups (1.17) with NAD+ or NADP+ as acceptor (1.17.1)
- C12Y117/01002—4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (1.17.1.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
- C12Y117/07—Oxidoreductases acting on CH or CH2 groups (1.17) with an iron-sulfur protein as acceptor (1.17.7)
- C12Y117/07001—(E)-4-Hydroxy-3-methylbut-2-enyl-diphosphate synthase (1.17.7.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01148—4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (2.7.1.148)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/0706—2-C-Methyl-D-erythritol 4-phosphate cytidylyltransferase (2.7.7.60)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03027—Isoprene synthase (4.2.3.27)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y406/00—Phosphorus-oxygen lyases (4.6)
- C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
- C12Y406/01012—2-C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (4.6.1.12)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361774342P | 2013-03-07 | 2013-03-07 | |
| US61/774,342 | 2013-03-07 | ||
| US201461928333P | 2014-01-16 | 2014-01-16 | |
| US61/928,333 | 2014-01-16 | ||
| PCT/US2014/021258 WO2014138419A1 (en) | 2013-03-07 | 2014-03-06 | Compositions and methods for biological production of isoprene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015131480A true RU2015131480A (ru) | 2017-04-12 |
Family
ID=51491962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015131480A RU2015131480A (ru) | 2013-03-07 | 2014-03-06 | Композиции и способы для биологического получения изопрена |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20160017374A1 (enExample) |
| EP (1) | EP2964748A4 (enExample) |
| JP (1) | JP2016508737A (enExample) |
| KR (1) | KR20150125653A (enExample) |
| CN (1) | CN105008514A (enExample) |
| AU (1) | AU2014225631A1 (enExample) |
| BR (1) | BR112015021003A2 (enExample) |
| CA (1) | CA2901588A1 (enExample) |
| RU (1) | RU2015131480A (enExample) |
| WO (1) | WO2014138419A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9695447B2 (en) * | 2012-12-27 | 2017-07-04 | Sekisui Chemical Co., Ltd. | Recombinant cell and method for producing isoprene |
| CA2914641A1 (en) | 2013-06-18 | 2014-12-24 | Calysta, Inc. | Compositions and methods for biological production of lactate from c1 compounds using lactate dehydrogenase transformants |
| JP2017504329A (ja) | 2014-01-16 | 2017-02-09 | キャリスタ， インコーポレイテッド | アミノ酸の増強された産生のための微生物および関連する方法 |
| DK3158065T3 (en) | 2014-06-18 | 2019-04-08 | Calysta Inc | NUCLEIC ACIDS AND VECTORS FOR USE WITH METHANOTROPHIC BACTERIES |
| JP2016059313A (ja) * | 2014-09-17 | 2016-04-25 | 積水化学工業株式会社 | 組換え細胞、並びに、イソプレン又は環式イソプレノイドの生産方法 |
| DE102015103608A1 (de) * | 2015-03-11 | 2016-09-15 | Basf Se | Verfahren zur mikrobiellen de novo Synthese von Terpenen |
| EP3292208B1 (en) | 2015-05-06 | 2020-08-19 | Trelys, Inc. | Compositions and methods for biological production of methionine |
| EP3294758A1 (en) | 2015-05-13 | 2018-03-21 | Calysta, Inc. | Proline auxotrophs |
| US20170145441A1 (en) * | 2015-08-17 | 2017-05-25 | INVISTA North America S.à.r.l. | Methods, hosts, and reagents related thereto for production of unsaturated pentahydrocarbons, derivatives and intermediates thereof |
| US10533192B2 (en) | 2015-12-22 | 2020-01-14 | Nutech Ventures | Production of isoprene by methane-producing archaea |
| KR102546640B1 (ko) * | 2016-01-26 | 2023-06-22 | 에스케이이노베이션 주식회사 | 재조합 호염성 메탄균주를 이용한 이소프렌의 제조방법 |
| JP2018014960A (ja) * | 2016-07-29 | 2018-02-01 | 横浜ゴム株式会社 | 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド |
| CN109689857A (zh) * | 2016-10-28 | 2019-04-26 | 积水化学工业株式会社 | 重组细胞、以及异戊二烯或萜的生产方法 |
| WO2019006257A1 (en) * | 2017-06-30 | 2019-01-03 | Invista North America .S.A.R.L. | METHODS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS |
| US11634733B2 (en) | 2017-06-30 | 2023-04-25 | Inv Nylon Chemicals Americas, Llc | Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof |
| US11505809B2 (en) | 2017-09-28 | 2022-11-22 | Inv Nylon Chemicals Americas Llc | Organisms and biosynthetic processes for hydrocarbon synthesis |
| US11180707B2 (en) * | 2018-08-03 | 2021-11-23 | Faramaz Fred Faramarzi | System and method for duplicating flammable gas |
| CN109943493B (zh) * | 2019-04-17 | 2021-05-18 | 天津大学 | 实现通用酶催化功能多样性的突变体菌株及其构建方法 |
| JP7754406B2 (ja) * | 2021-03-26 | 2025-10-15 | 三菱ケミカル株式会社 | イソプレン産生能を有する遺伝子改変微生物およびこれを用いたイソプレン製造方法 |
| CN119736218A (zh) * | 2023-09-19 | 2025-04-01 | 西安卓虹超源生物科技有限公司 | 一种萜类化合物的生产及菌株 |
| KR20250113943A (ko) * | 2024-01-18 | 2025-07-28 | 한국생명공학연구원 | 메탄으로부터 이소프렌 생산능을 갖는 형질전환체 |
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| US6818424B2 (en) * | 2000-09-01 | 2004-11-16 | E. I. Du Pont De Nemours And Company | Production of cyclic terpenoids |
| ATE384119T1 (de) * | 2000-09-29 | 2008-02-15 | Cargill Inc | Isoprenoidproduktion |
| US7947478B2 (en) * | 2006-06-29 | 2011-05-24 | The Regents Of The University Of California | Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria |
| BRPI0823506A8 (pt) * | 2007-12-13 | 2018-05-15 | Danisco Us Inc Genencor Div | composições e métodos para a produção de isoprene |
| CA2737223A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
| TW201412988A (zh) * | 2009-06-17 | 2014-04-01 | Danisco Us Inc | 使用ｄｘｐ及ｍｖａ途徑之改良之異戊二烯製造 |
| DE102012012913A1 (de) * | 2012-06-27 | 2014-01-02 | Beatrice Saier | Vorrichtung und Verfahren zur schaltbaren Förderung wenigstens eines Mediums |
| BR112015014843A2 (pt) * | 2012-12-21 | 2017-10-10 | Danisco Us Inc | produção de isopreno, isoprenoide, e precursores de isoprenoide usando uma via de mevalonato inferior alternativa |
| US9695447B2 (en) * | 2012-12-27 | 2017-07-04 | Sekisui Chemical Co., Ltd. | Recombinant cell and method for producing isoprene |
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2014
- 2014-03-06 BR BR112015021003A patent/BR112015021003A2/pt not_active IP Right Cessation
- 2014-03-06 US US14/773,118 patent/US20160017374A1/en not_active Abandoned
- 2014-03-06 WO PCT/US2014/021258 patent/WO2014138419A1/en not_active Ceased
- 2014-03-06 AU AU2014225631A patent/AU2014225631A1/en not_active Abandoned
- 2014-03-06 EP EP14760094.4A patent/EP2964748A4/en not_active Withdrawn
- 2014-03-06 RU RU2015131480A patent/RU2015131480A/ru not_active Application Discontinuation
- 2014-03-06 KR KR1020157023131A patent/KR20150125653A/ko not_active Withdrawn
- 2014-03-06 CN CN201480012326.4A patent/CN105008514A/zh active Pending
- 2014-03-06 JP JP2015561662A patent/JP2016508737A/ja active Pending
- 2014-03-06 CA CA2901588A patent/CA2901588A1/en not_active Abandoned
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| AU2014225631A1 (en) | 2015-08-13 |
| WO2014138419A1 (en) | 2014-09-12 |
| CN105008514A (zh) | 2015-10-28 |
| BR112015021003A2 (pt) | 2017-07-18 |
| JP2016508737A (ja) | 2016-03-24 |
| CA2901588A1 (en) | 2014-09-12 |
| KR20150125653A (ko) | 2015-11-09 |
| EP2964748A4 (en) | 2016-11-02 |
| EP2964748A1 (en) | 2016-01-13 |
| US20160017374A1 (en) | 2016-01-21 |
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| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
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