JP2016508737A - イソプレンの生物学的産生のための組成物および方法 - Google Patents

イソプレンの生物学的産生のための組成物および方法 Download PDF

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JP2016508737A
JP2016508737A JP2015561662A JP2015561662A JP2016508737A JP 2016508737 A JP2016508737 A JP 2016508737A JP 2015561662 A JP2015561662 A JP 2015561662A JP 2015561662 A JP2015561662 A JP 2015561662A JP 2016508737 A JP2016508737 A JP 2016508737A
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methane
isoprene
nucleic acid
bacterium
utilizing
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JP2016508737A5 (enExample
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エッフェンディ レオナルド，
エッフェンディ レオナルド，
ジェレミー ミンシュル，
ジェレミー ミンシュル，
ジョン ネス，
ジョン ネス，
トーマス ジョセフ パーセル，
トーマス ジョセフ パーセル，
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キャリスタ， インコーポレイテッド
キャリスタ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C11/00—Aliphatic unsaturated hydrocarbons
    • C07C11/02—Alkenes
    • C07C11/10—Alkenes with five carbon atoms
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    • C12N15/09—Recombinant DNA-technology
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    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0093—Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
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    • C12N9/88—Lyases (4.)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01267—1-Deoxy-D-xylulose-5-phosphate reductoisomerase (1.1.1.267)
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    • C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
    • C12Y117/01—Oxidoreductases acting on CH or CH2 groups (1.17) with NAD+ or NADP+ as acceptor (1.17.1)
    • C12Y117/01002—4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (1.17.1.2)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
    • C12Y117/07—Oxidoreductases acting on CH or CH2 groups (1.17) with an iron-sulfur protein as acceptor (1.17.7)
    • C12Y117/07001—(E)-4-Hydroxy-3-methylbut-2-enyl-diphosphate synthase (1.17.7.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01148—4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (2.7.1.148)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/0706—2-C-Methyl-D-erythritol 4-phosphate cytidylyltransferase (2.7.7.60)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027—Isoprene synthase (4.2.3.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Y406/00—Phosphorus-oxygen lyases (4.6)
    • C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
    • C12Y406/01012—2-C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (4.6.1.12)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

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  • Genetics & Genomics (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
JP2015561662A 2013-03-07 2014-03-06 イソプレンの生物学的産生のための組成物および方法 Pending JP2016508737A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361774342P 2013-03-07 2013-03-07
US61/774,342 2013-03-07
US201461928333P 2014-01-16 2014-01-16
US61/928,333 2014-01-16
PCT/US2014/021258 WO2014138419A1 (en) 2013-03-07 2014-03-06 Compositions and methods for biological production of isoprene

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JP2016508737A true JP2016508737A (ja) 2016-03-24
JP2016508737A5 JP2016508737A5 (enExample) 2017-04-06

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US (1) US20160017374A1 (enExample)
EP (1) EP2964748A4 (enExample)
JP (1) JP2016508737A (enExample)
KR (1) KR20150125653A (enExample)
CN (1) CN105008514A (enExample)
AU (1) AU2014225631A1 (enExample)
BR (1) BR112015021003A2 (enExample)
CA (1) CA2901588A1 (enExample)
RU (1) RU2015131480A (enExample)
WO (1) WO2014138419A1 (enExample)

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JP2018014960A (ja) * 2016-07-29 2018-02-01 横浜ゴム株式会社 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド

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US9695447B2 (en) * 2012-12-27 2017-07-04 Sekisui Chemical Co., Ltd. Recombinant cell and method for producing isoprene
ES2757913T3 (es) 2013-06-18 2020-04-30 Calysta Inc Composiciones y métodos para la producción biológica de lactato a partir de compuestos de C1 mediante el uso de transformantes de deshidrogenasa láctica
WO2015109265A1 (en) 2014-01-16 2015-07-23 Calysta, Inc. Microorganisms for the enhanced production of amino acids and related methods
US10443060B2 (en) 2014-06-18 2019-10-15 Calysta, Inc. Nucleic acids and vectors for use with methanotrophic bacteria
JP2016059313A (ja) * 2014-09-17 2016-04-25 積水化学工業株式会社 組換え細胞、並びに、イソプレン又は環式イソプレノイドの生産方法
DE102015103608A1 (de) * 2015-03-11 2016-09-15 Basf Se Verfahren zur mikrobiellen de novo Synthese von Terpenen
JP2018516552A (ja) 2015-05-06 2018-06-28 トレリス， インコーポレイテッド メチオニンの生物学的産生のための組成物及び方法
CA2984135A1 (en) 2015-05-13 2016-11-17 Calysta, Inc. Proline auxotrophs
US20180291401A1 (en) * 2015-08-17 2018-10-11 Invista North America S.A.R.L. Methods, hosts, and reagents related thereto for production of unsaturated pentahydrocarbons, derivatives and intermediates thereof
US10533192B2 (en) 2015-12-22 2020-01-14 Nutech Ventures Production of isoprene by methane-producing archaea
KR102546640B1 (ko) 2016-01-26 2023-06-22 에스케이이노베이션 주식회사 재조합 호염성 메탄균주를 이용한 이소프렌의 제조방법
JPWO2018079619A1 (ja) * 2016-10-28 2019-09-19 積水化学工業株式会社 組換え細胞、並びに、イソプレン又はテルペンの生産方法
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
US11180707B2 (en) * 2018-08-03 2021-11-23 Faramaz Fred Faramarzi System and method for duplicating flammable gas
CN109943493B (zh) * 2019-04-17 2021-05-18 天津大学 实现通用酶催化功能多样性的突变体菌株及其构建方法
JP7754406B2 (ja) * 2021-03-26 2025-10-15 三菱ケミカル株式会社 イソプレン産生能を有する遺伝子改変微生物およびこれを用いたイソプレン製造方法
CN119736218A (zh) * 2023-09-19 2025-04-01 西安卓虹超源生物科技有限公司 一种萜类化合物的生产及菌株
WO2025155137A1 (ko) * 2024-01-18 2025-07-24 한국생명공학연구원 메탄으로부터 이소프렌 생산능을 갖는 형질전환체
WO2026010860A1 (en) 2024-07-02 2026-01-08 Bp Corporation North America Inc. Recombinant microorganisms for isoprene production
US20260055330A1 (en) * 2024-07-26 2026-02-26 Visolis, Inc. High energy density rocket fuel compositions
WO2026122827A2 (en) 2024-12-05 2026-06-11 Bp Corporation North America Inc. Ppi-dependent kdg kinases and uses thereof
WO2026122843A2 (en) 2024-12-05 2026-06-11 Bp Corporation North America Inc. Recombinant microorganisms for βeta-myrcene and nerol production

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WO2010148150A1 (en) * 2009-06-17 2010-12-23 Danisco Us Inc. Improved isoprene production using the dxp and mva pathway

Cited By (1)

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Publication number Priority date Publication date Assignee Title
JP2018014960A (ja) * 2016-07-29 2018-02-01 横浜ゴム株式会社 発現ベクター、形質転換された藻類、形質転換された珪藻、及び、ポリヌクレオチド

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CA2901588A1 (en) 2014-09-12
US20160017374A1 (en) 2016-01-21
KR20150125653A (ko) 2015-11-09
CN105008514A (zh) 2015-10-28
EP2964748A4 (en) 2016-11-02
RU2015131480A (ru) 2017-04-12
WO2014138419A1 (en) 2014-09-12
EP2964748A1 (en) 2016-01-13
AU2014225631A1 (en) 2015-08-13
BR112015021003A2 (pt) 2017-07-18

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